Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Gewählte Publikation:

Freigassner, P; Ardjomand, N; Radner, H; El-Shabrawi, Y.
Coinfection of the retina by Epstein-Barr virus and cytomegalovirus in an AIDS patient.
Am J Ophthalmol. 2002; 134(2):275-277 (- Case Report)
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Autor/innen der Med Uni Graz:
Ardjomand Navid
El-Shabrawi Yosuf
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Abstract:
PURPOSE: To report an immunohistochemically proven case of a coinfection of the retina by Epstein-Barr virus and cytomegalovirus in a patient with acquired immunodeficiency syndrome (AIDS). DESIGN: Interventional case report. METHODS: Postmortem evaluation of retinal tissue of a 45-year-old female AIDS patient with atypical fibrinous iridocyclitis and vitritis in course of a cytomegalovirus retinitis in the left eye was performed for evidence of dual infection with cytomegalovirus and other herpes group viruses. Immunohistochemical examination with double-staining techniques and antibodies against Epstein-Barr virus and cytomegalovirus was used. RESULTS: In the retina of the left eye, cells reacting with antibodies against cytomegalovirus and cells stained with antibodies against Epstein-Barr virus were detected in the layer of ganglionic cells and the inner granular cell layer. CONCLUSION: Epstein-Barr virus coinfection should be taken into consideration in unusual cases of necrotizing cytomegalovirus retinitis in AIDS patients.
Find related publications in this database (using NLM MeSH Indexing)
AIDS-Related Opportunistic Infections - complications
Antibodies, Viral - diagnostic use
Cytomegalovirus - immunology
Cytomegalovirus Retinitis - complications
Epstein-Barr Virus Infections - complications
Fatal Outcome - complications
Female - complications
Herpesvirus 4, Human - immunology
Humans - immunology
Immunoenzyme Techniques - immunology
Middle Aged - immunology
Retina - virology

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