Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Gewählte Publikation:

Kenner, L; Schwarzl, F; Moshammer, H; Haas, F; Hoefler, G; Pierer, G.
Venous thrombosis in a replanted finger with underlying factor V Leiden mutation.
Br J Plast Surg. 1998; 51(1):57-58 (- Case Report)
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Autor/innen der Med Uni Graz:
Haas Franz
Hoefler Gerald
Kenner Lukas
Schwarzl Franz
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Abstract:
Resistance to activated protein C (APC resistance) was described recently as a cause for thrombophilia. APC inactivates coagulation co-factors Va and VIIIa. A single base-pair mutation changing Arg506 to Gln at the APC cleavage site of the factor V gene leads to a factor V Leiden variant, which is the most frequent cause of APC resistance. Recently, its role in peripheral venous thrombosis during pregnancy was described. We here report a case with thrombosis of the venous anastomoses after finger replantation with resistance to activated protein C associated with factor V Leiden mutation.
Find related publications in this database (using NLM MeSH Indexing)
Adult -
Factor V - genetics
Finger Injuries - surgery
Humans -
Male -
Mutation -
Postoperative Complications -
Protein C - physiology
Replantation -
Thrombophlebitis - genetics

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