Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Gewählte Publikation:

Dobnig, H; Silly, H; Ohlinger, W; Neubauer, M; Leb, G; Krejs, GJ.
Successful treatment of primary adrenal insufficiency due to malignant non-Hodgkin's lymphoma.
Clin Investig. 1992; 70(10):938-941 (- Case Report)
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Autor/innen der Med Uni Graz:
Dobnig Harald
Krejs Günter Josef
Leb Georg
Sill Heinz
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Abstract:
Although the adrenal glands are frequently the site of tumor metastases, adrenal insufficiency is exceedingly rare. We report on a patient with high-grade B-cell centroblastic lymphoma who initially presented with right axillary lymphadenopathy and bilateral adrenal masses. Four months after axillary lymphadenectomy the patient developed overt signs of Addison's disease. He recovered promptly after initiation of hormone replacement therapy and bilateral adrenalectomy. At present, 16 months after additional chemo- and radiation therapy the patient is considered free of tumor. To our knowledge this is the first report on a patient who presented with adrenal insufficiency in the course of non-Hodgkin's lymphoma and who was successfully treated. Demonstrating this case, we would also like to stress that the development of adrenal insufficiency does not necessarily indicate widespread tumor manifestation in patients with non-Hodgkin's lymphoma.
Find related publications in this database (using NLM MeSH Indexing)
Adrenal Cortex Hormones - therapeutic use
Adrenal Insufficiency - etiology Adrenal Insufficiency - therapy
Adrenalectomy -
Combined Modality Therapy -
Humans -
Lymphatic Diseases - etiology
Lymphoma, B-Cell - complications
Male -
Middle Aged -

Find related publications in this database (Keywords)
Adrenal Insufficiency
Non-Hodgkins Lymphoma
Bilateral Adrenal Masses
Cortisol Replacement Therapy
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