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Gewählte Publikation:

SHR Neuro Krebs Kardio Lipid

Luecke, E; Ganzert, C; Vielhaber, S; Haybaeck, J; Jechorek, D; Mawrin, C; Schreiber, J.
Immune Checkpoint Inhibitor-induced Fatal Myositis in a Patient With Squamous Cell Carcinoma and a History of Thymoma.
Clin Lung Cancer. 2020; 21(4):e246-e249-e246-e249 (- Case Report)
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Autor/innen der Med Uni Graz:
Haybäck Johannes
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Abstract:
Immune checkpoint inhibitors (ICIs) substantially improve prognosis in patients with non-small-cell lung cancer. Myositis and myocarditis are very rare, but potentially life threatening, immune-related adverse events associated with ICI therapy. Patients with thymic epithelial tumors are at increased risk for these severe complications. A history of cured thymic epithelial tumors without recurrence seems to be a relevant risk for patients treated with ICIs irrespective of the indication. (C) 2020 Elsevier Inc. All rights reserved.

Find related publications in this database (Keywords)
Immune checkpoint inhibition
Immune-related adverse events
Myocarditis
T-cell receptor clones
Treatment of autoimmune toxicities
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