Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

Logo MUG-Forschungsportal

Gewählte Publikation:

SHR Neuro Krebs Kardio Lipid Stoffw Microb

Smith, EE; Biessels, GJ; De Guio, F; de Leeuw, FE; Duchesne, S; Düring, M; Frayne, R; Ikram, MA; Jouvent, E; MacIntosh, BJ; Thrippleton, MJ; Vernooij, MW; Adams, H; Backes, WH; Ballerini, L; Black, SE; Chen, C; Corriveau, R; DeCarli, C; Greenberg, SM; Gurol, ME; Ingrisch, M; Job, D; Lam, BYK; Launer, LJ; Linn, J; McCreary, CR; Mok, VCT; Pantoni, L; Pike, GB; Ramirez, J; Reijmer, YD; Romero, JR; Ropele, S; Rost, NS; Sachdev, PS; Scott, CJM; Seshadri, S; Sharma, M; Sourbron, S; Steketee, RME; Swartz, RH; van Oostenbrugge, R; van Osch, M; van Rooden, S; Viswanathan, A; Werring, D; Dichgans, M; Wardlaw, JM.
Harmonizing brain magnetic resonance imaging methods for vascular contributions to neurodegeneration.
Alzheimers Dement (Amst). 2019; 11(4): 191-204. Doi: 10.1016/j.dadm.2019.01.002 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG


Co-Autor*innen der Med Uni Graz
Ropele Stefan

Dimensions Citations:

Plum Analytics:

Scite (citation analytics):

Many consequences of cerebrovascular disease are identifiable by magnetic resonance imaging (MRI), but variation in methods limits multicenter studies and pooling of data. The European Union Joint Program on Neurodegenerative Diseases (EU JPND) funded the HARmoNizing Brain Imaging MEthodS for VaScular Contributions to Neurodegeneration (HARNESS) initiative, with a focus on cerebral small vessel disease. Surveys, teleconferences, and an in-person workshop were used to identify gaps in knowledge and to develop tools for harmonizing imaging and analysis. A framework for neuroimaging biomarker development was developed based on validating repeatability and reproducibility, biological principles, and feasibility of implementation. The status of current MRI biomarkers was reviewed. A website was created at with acquisition protocols, a software database, rating scales and case report forms, and a deidentified MRI repository. The HARNESS initiative provides resources to reduce variability in measurement in MRI studies of cerebral small vessel disease.

Find related publications in this database (Keywords)
Cerebrovascular disease
Magnetic resonance imaging
© Med Uni Graz Impressum