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SHR Neuro Krebs Kardio Lipid Stoffw Microb

Wallner, M; Eaton, DM; von Lewinski, D; Sourij, H.
Revisiting the Diabetes-Heart Failure Connection.
Curr Diab Rep. 2018; 18(12):134-134 Doi: 10.1007/s11892-018-1116-z [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG


Führende Autor*innen der Med Uni Graz
Sourij Harald
Wallner Markus
Co-Autor*innen der Med Uni Graz
von Lewinski Dirk

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To summarize current clinical data investigating the link between diabetes and heart failure pathophysiology, the association of glucose control with heart failure, and the impact of current antihyperglycemic drugs on heart failure. Although heart failure is one of the most prevalent outcomes occurring in real life and cardiovascular outcome trials, insufficient attention was given to this condition in diabetes research over the last decades. With both beneficial and detrimental findings for heart failure hospitalization in the health authority-mandated outcome trials for new antihyperglycemic agents, research on heart failure and its interplay with diabetes mellitus gained momentum. Diabetes mellitus and heart failure are both prevalent and intertwined conditions. While currently available heart failure therapies have a similar degree of effectiveness in patients with and without diabetes, the choice of glucose-lowering agents can substantially affect heart failure-related outcome.

Find related publications in this database (Keywords)
Antihyperglycemic drug
SGLT-2 inhibitors
Incretin-based therapy
Heart failure
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