Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Knoflach, M; Lang, W; Seyfang, L; Fertl, E; Oberndorfer, S; Daniel, G; Seifert-Held, T; Brainin, M; Krebs, S; Matosevic, B; Töll, T; Kiechl, S; Willeit, J; Ferrari, J; Austrian Stroke Unit Collaborators.
Predictive value of ABCD2 and ABCD3-I scores in TIA and minor stroke in the stroke unit setting.
Neurology. 2016; 87(9):861-869
Doi: 10.1212/WNL.0000000000003033
Web of Science
PubMed
FullText
FullText_MUG
- Co-Autor*innen der Med Uni Graz
- Seifert-Held Thomas
- Study Group Mitglieder der Med Uni Graz:
- Fazekas Franz
- Gattringer Thomas
- Niederkorn Kurt
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- Abstract:
- It is not clear whether risk scores for early stroke recurrence after TIA that have been mainly established in outpatient and emergency department settings are valid on the background of highly specialized stroke unit care. ABCD2 and ABCD3-I scores have been prospectively documented in a cohort of patients admitted to Austrian stroke units within 24 hours of symptom onset with TIA or minor stroke (NIH Stroke Scale score <4). A total of 5,237 TIA and minor stroke patients met inclusion criteria, with 3-month follow-up data available on 2,457. Early and 3-month stroke were observed in 2.4% and 4.2% of the study population. The probability of early stroke during the stroke unit stay (median 2 [interquartile range 1-3] days) steadily increased from 0% to 4.8% and 0% to 16.7% with increasing ABCD2 and ABCD3-I score points, respectively. On 3-month follow-up, stroke risk increased from 0% to 8.0% and 0% to 23.8% with increasing ABCD2 and ABCD3-I score points, respectively. Of the individual score components, age, blood pressure, and diabetes were not related to early or 3-month stroke, whereas clinical presentation (C), symptom duration (D), and cerebral as well as carotid imaging (I) were and accounted for the information provided by the full scores. Standard ABCD2 and ABCD3-I scores are useful instruments to estimate the probability of early and 3-month stroke in TIA and minor stroke patients treated at specialized stroke units, with C, D, and I being the most important score components in this setting. © 2016 American Academy of Neurology.
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- Aged -
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