Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Wattjes, MP; Rovira, À; Miller, D; Yousry, TA; Sormani, MP; de Stefano, MP; Tintoré, M; Auger, C; Tur, C; Filippi, M; Rocca, MA; Fazekas, F; Kappos, L; Polman, C; Frederik Barkhof, C; Xavier Montalban, C; MAGNIMS study group.
Evidence-based guidelines: MAGNIMS consensus guidelines on the use of MRI in multiple sclerosis--establishing disease prognosis and monitoring patients.
Nat Rev Neurol. 2015; 11(10):597-606
Doi: 10.1038/nrneurol.2015.157
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- Co-Autor*innen der Med Uni Graz
- Fazekas Franz
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- Abstract:
- The role of MRI in the assessment of multiple sclerosis (MS) goes far beyond the diagnostic process. MRI techniques can be used as regular monitoring to help stage patients with MS and measure disease progression. MRI can also be used to measure lesion burden, thus providing useful information for the prediction of long-term disability. With the introduction of a new generation of immunomodulatory and/or immunosuppressive drugs for the treatment of MS, MRI also makes an important contribution to the monitoring of treatment, and can be used to determine baseline tissue damage and detect subsequent repair. This use of MRI can help predict treatment response and assess the efficacy and safety of new therapies. In the second part of the MAGNIMS (Magnetic Resonance Imaging in MS) network's guidelines on the use of MRI in MS, we focus on the implementation of this technique in prognostic and monitoring tasks. We present recommendations on how and when to use MRI for disease monitoring, and discuss some promising MRI approaches that may be introduced into clinical practice in the near future.
- Find related publications in this database (using NLM MeSH Indexing)
- Brain - drug effects
- Brain - pathology
- Consensus -
- Disease Progression -
- Evidence-Based Medicine -
- Humans -
- Immunotherapy - methods
- Magnetic Resonance Imaging - methods
- Multiple Sclerosis - diagnosis
- Multiple Sclerosis - drug therapy
- Multiple Sclerosis - pathology
- Prognosis -