Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
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SHR Neuro Krebs Kardio Lipid Stoffw Microb
Verheyen, ND; Kienreich, K; Gaksch, M; van, Ballegooijen, AJ; Grübler, MR; Hartaigh, BÓ; Schmid, J; Fahrleitner-Pammer, A; Kraigher-Krainer, E; Colantonio, C; Belyavskiy, E; Treiber, G; Catena, C; Brussee, H; Pieske, B; März, W; Tomaschitz, A; Pilz, S.
Plasma Parathyroid Hormone Is Independently Related to Nocturnal Blood Pressure in Hypertensive Patients: The Styrian Hypertension Study.
J Clin Hypertens (Greenwich). 2016; 18(6):543-50
Doi: 10.1111/jch.12710
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- Führende Autor*innen der Med Uni Graz
- Kienreich Katharina
- Verheyen Nicolas Dominik
- Co-Autor*innen der Med Uni Graz
- Belyavskiy Evgeny
- Brussee Helmut
- Colantonio Caterina
- Fahrleitner-Pammer Astrid
- Grübler Martin
- Keppel Martin
- Kraigher-Krainer Elisabeth
- März Winfried
- Pieske Burkert Mathias
- Pilz Stefan
- Schmid Johannes
- Tomaschitz Andreas
- Treiber Gerlies
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- Abstract:
- High parathyroid hormone (PTH) has been linked with high blood pressure (BP), but the relationship with 24-hour ambulatory blood pressure monitoring is largely unknown. The authors therefore analyzed cross-sectional data of 292 hypertensive patients participating in the Styrian Hypertension Study (mean age, 61±11 years; 53% women). Median plasma PTH (interquartile range) determined after an overnight fast was 49 pg/mL (39-61), mean daytime BP was 131/80±12/9 mm Hg, and mean nocturnal BP was 115/67±14/9 mm Hg. In multivariate regression analyses adjusted for BP and PTH-modifying parameters, PTH was significantly related to nocturnal systolic and diastolic BP (adjusted β-coefficient 0.140 [P=.03] and 0.175 [P<.01], respectively). PTH was not correlated with daytime BP readings. These data suggest a direct interrelationship between PTH and nocturnal BP regulation. Whether lowering high PTH concentrations reduces the burden of high nocturnal BP remains to be shown in future studies.
- Find related publications in this database (using NLM MeSH Indexing)
- Aged - administration & dosage
- Blood Pressure - physiology
- Blood Pressure Monitoring, Ambulatory - administration & dosage
- Circadian Rhythm - physiology
- Cross-Sectional Studies - administration & dosage
- Female - administration & dosage
- Humans - administration & dosage
- Hypertension - blood, physiopathology
- Male - administration & dosage
- Middle Aged - administration & dosage
- Parathyroid Hormone - blood
- Regression Analysis - administration & dosage
- Risk Factors - administration & dosage