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Gewählte Publikation:

SHR Neuro Krebs Kardio Lipid Stoffw Microb

Absenger, G; Szkandera, J; Stotz, M; Postlmayr, U; Pichler, M; Ress, AL; Schaberl-Moser, R; Loibner, H; Samonigg, H; Gerger, A.
Preoperative neutrophil-to-lymphocyte ratio predicts clinical outcome in patients with stage II and III colon cancer.
Anticancer Res. 2013; 33(10):4591-4594
Web of Science PubMed


Führende Autor*innen der Med Uni Graz
Absenger Gudrun
Gerger Armin
Co-Autor*innen der Med Uni Graz
Lembeck Anna Lena
Pichler Martin
Samonigg Hellmut
Schaberl-Moser Renate
Stotz Michael
Szkandera Joanna

Dimensions Citations:

Plum Analytics:
Aim/Background: The neutrophil-to-lymphocyte ratio (NLR), a combined indicator of inflammation and immunology, is as yet unidentified regarding the clinical outcome of stage II and III colon cancer patients. We evaluated the effect of NLR on time-to-recurrence (TTR) and overall survival (OS) in selected patients. Patients and Methods: A total of 504 patients with stage II and III colon cancer were included in this retrospective study. Preoperative NLR with a cut-off level of 4 was associated with TTR and OS. Results: In univariate analysis, elevated NLR was significantly associated with decreased TTR (p=0.001) and remained significant in multivariate analysis (p=0.006). Patients with NLR >4 showed a median TTR of 62.2 months. In contrast, patients with NLR <= 4 had a median TTR of 92.6 months. Conclusion: This study suggests that preoperative NLR may be an independent prognostic marker for TTR in stage II and III colon cancer patients.
Find related publications in this database (using NLM MeSH Indexing)
Adult -
Aged -
Aged, 80 and over -
Colonic Neoplasms - immunology Colonic Neoplasms - mortality Colonic Neoplasms - pathology
Disease-Free Survival -
Female -
Humans -
Kaplan-Meier Estimate -
Lymphocyte Count -
Lymphocytes - immunology
Male -
Middle Aged -
Multivariate Analysis -
Neoplasm Staging -
Neutrophils - immunology
Preoperative Period -
Prognosis -
Proportional Hazards Models -
Retrospective Studies -
Treatment Outcome -

Find related publications in this database (Keywords)
Neutrophil-to-lymphocyte ratio
colon cancer
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