Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Parente, JN; Talhari, C; Ginter-Hanselmayer, G; Schettini, AP; Eiras, Jda C; de Souza, JV; Tavares, R; Buzina, W; Brunasso, AM; Massone, C.
Subcutaneous phaeohyphomycosis in immunocompetent patients: two new cases caused by Exophiala jeanselmei and Cladophialophora carrionii.
Mycoses. 2011; 54(3):265-269
Doi: 10.1111/j.1439-0507.2009.01795.x
(- Case Report)
Web of Science
PubMed
FullText
FullText_MUG
- Führende Autor*innen der Med Uni Graz
- Massone Cesare
- Co-Autor*innen der Med Uni Graz
- Brunasso Vernetti Alexandra Maria
- Buzina Walter
- Ginter-Hanselmayer Gabriele
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- Abstract:
- Phaeohyphomycosis is a distinct mycotic infection of the skin or internal organs caused by darkly pigmented (dematiaceous) fungi, which are widely distributed in the environment. Phaeohyphomycosis is most frequently an opportunistic infection in immunosuppressed patients (HIV, corticotherapy, transplant patients) or is frequently associated with chronic diseases and diabetes. The spectrum of the disease is broad and includes superficial infections, onychomycosis, subcutaneous infections, keratitis, allergic disease, pneumonia, brain abscesses and disseminated disease. Rarely, immunocompetent patients may be affected. We describe two new cases of subcutaneous phaeohyphomycosis in immunocompetent patients: in the first patient, the causative agent was Exophiala jeanselmei, a common cause of phaeohyphomycosis; and in the second, Cladophialophora carrionii, which could be identified by culture. Cladophialophora carrionii is mainly the aetiological agent of chromoblastomycosis and only rarely the cause of phaeohyphomycosis. The first patient was treated with surgical excision and oral itraconazole, and the second patient responded to oral itraconazole only. Lesions improved in both patients and no recurrence was observed at follow-up visits. © 2009 Blackwell Verlag GmbH.
- Find related publications in this database (using NLM MeSH Indexing)
- Antifungal Agents - administration & dosage
- Ascomycota - isolation & purification
- Debridement -
- Dermatomycoses - diagnosis Dermatomycoses - drug therapy Dermatomycoses - pathology Dermatomycoses - surgery
- Exophiala - isolation & purification
- Histocytochemistry -
- Humans -
- Itraconazole - administration & dosage
- Male -
- Microscopy -
- Middle Aged -
- Soft Tissue Infections - diagnosis Soft Tissue Infections - drug therapy Soft Tissue Infections - pathology Soft Tissue Infections - surgery
- Subcutaneous Tissue - microbiology Subcutaneous Tissue - pathology Subcutaneous Tissue - surgery