Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Ivastinovic, D; Brandner, M; Georgi, T; Langmann, G; Wedrich, A; Velikay-Parel, M.
Übersicht über die Entwicklung des künstlichen Sehens an der Universitäts-Augenklinik Graz
Spektrum der Augenheilkunde. 2009; 23: 312-318.
Doi: 10.1007/s00717-009-0356-3
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- Führende Autor*innen der Med Uni Graz
- Ivastinovic Domagoj
- Velikay-Parel Michaela
- Co-Autor*innen der Med Uni Graz
- Brandner Martina Christine
- Georgi Thomas Patrick
- Langmann Gerald
- Wedrich Andreas
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- Abstract:
- Retinitis pigmentosa is a retinal disease leading to photoreceptor and ganglion cell loss. Despite of the significant cell loss in the end stage of the disease, high percentage of vital ganglion cells remain intact. This observation led to the development of retinal implants, which should improve the visual perception and orientation of patients with severe visual impairment or blindness. The stimulation of highly differentiated ganglion cells will lead to uncommon light perceptions, which will be transformed into a meaningful picture after a learning process. The feasibility and stability of a new fixation method for epiretinal implants was investigated in an animal trial at the University Eye Hospital. During the development of the implantation method special care was taken to the later option of safe explantation procedure. In this way the implant can be removed atraumatically, if required, or exchanged for a new implant with new technology. The tests used in ophthalmology are not suitable for evaluation of the progress after implantation of retinal prostheses. On the basis of grating acuity measurement in low vision, the Modified Grating test was developed and tested. To measure the orientation (task performance, functional vision) a maze with obstacles, the Graz Mobility test, was developed and investigated. This review gives an overview about the research done on this field at the University Eye Hospital Graz.
- Find related publications in this database (Keywords)
- Retinal implants
- retinitis pigmentosa
- visual acuity test
- mobility test
- artificial vision