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SHR Neuro Krebs Kardio Lipid

Czermak, C; Wallner, SJ; Kresse, A; Schauer, S; Aigner, R; Hoefler, G; Lehofer, M; Liebmann, PM.
Baseline plasma epinephrine levels predict Wisconsin Card Sorting Test scores in healthy volunteers.
Psychoneuroendocrinology. 2009; 34(4):625-628
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Autor/innen der Med Uni Graz:
Aigner Reingard
Hoefler Gerald
Holasek Sandra Johanna
Kresse Adelheid
Schauer Silvia
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Abstract:
The present study was undertaken to further explore the potential neuropsychological information associated with baseline plasma levels of catecholamines and dopamine D3 receptor (DRD3) mRNA expression in peripheral blood lymphocytes (PBL). Baseline plasma norepinephrine and epinephrine levels and PBL DRD3 mRNA expression were compared with performance in the Wisconsin Card Sorting Test (WCST) in n=79 healthy volunteers (mean+/-S.D. age: 24.1+/-3.2 years, 34 males). After correction for multiple testing, we found that baseline plasma epinephrine levels predicted WCST total number of errors (Spearman's rho=-0.36, p<0.05), number of perseverative responses (Spearman's rho=-0.36, p<0.05) and percent conceptual level responses (Spearman's rho=0.37, p<0.05). Plasma norepinephrine levels and PBL DRD3 mRNA expression did not predict WCST scores, but PBL DRD3 mRNA expression correlated negatively with plasma epinephrine levels (Spearman's rho=-0.45, p<0.001). Further studies should be undertaken to explore possible neurophysiological links between plasma epinephrine levels and the neurobiology underlying cognitive performance.
Find related publications in this database (using NLM MeSH Indexing)
Adult -
Cognition - physiology
Discrimination (Psychology) - physiology
Epinephrine - blood
Female -
Games, Experimental -
Humans -
Lymphocytes - metabolism
Male -
Norepinephrine - blood
Personality - genetics Personality - physiology
Psychometrics -
RNA, Messenger - analysis
Reaction Time - physiology
Receptors, Dopamine D3 - genetics Receptors, Dopamine D3 - metabolism
Reference Values -
Young Adult -

Find related publications in this database (Keywords)
Plasma
Epinephrine
Norepinephrine
Lymphocytes
Dopamine D3 receptor
Wisconsin Card Sorting Test
Healthy humans
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