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SHR Neuro Krebs Kardio Lipid Stoffw Microb

Zollner-Schwetz, I; Auner, HW; Paulitsch, A; Buzina, W; Staber, PB; Ofner-Kopeinig, P; Reisinger, EC; Olschewski, H; Krause, R.
Oral and intestinal Candida colonization in patients undergoing hematopoietic stem-cell transplantation.
J Infect Dis. 2008; 198(1): 150-153. Doi: 10.1086/588827 [OPEN ACCESS]
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Führende Autor*innen der Med Uni Graz
Krause Robert
Zollner-Schwetz Ines
Co-Autor*innen der Med Uni Graz
Buzina Walter
Ofner-Kopeinig Petra
Olschewski Horst
Paulitsch-Fuchs Astrid Helga
Staber Philipp

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We investigated (1) the prevalence and quantity of, as well as risk factors for, orointestinal Candida colonization in patients undergoing hematopoietic stem-cell transplantation (HSCT) and (2) the genetic relatedness of colonizing C. albicans strains. Mouth-wash and stool samples were collected from 77 patients before they underwent HSCT and on days 1, 8, and 15 and were quantitatively cultured. C. albicans isolates were genotyped by microsatellite-marker analysis. The prevalence and quantity of orointestinal Candida colonization varied over time. In 48% (13/27) of multicolonized patients, the same Candida genotype was present in oral and intestinal samples. Oral colonization and decontamination of the gut by vancomycin and paromomycin were risk factors for intestinal Candida colonization.
Find related publications in this database (using NLM MeSH Indexing)
Adult -
Aged -
Anti-Bacterial Agents - adverse effects
Candida albicans - isolation and purification
Candidiasis - epidemiology Candidiasis - etiology Candidiasis - microbiology
Carrier State -
Female -
Hematopoietic Stem Cell Transplantation - adverse effects
Humans -
Immunocompromised Host -
Intestines - microbiology
Male -
Middle Aged -
Mouth - microbiology
Paromomycin - adverse effects
Prevalence -
Risk Factors -
Vancomycin - adverse effects

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