Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Bos, AF; Dibiasi, J; Tiessen, AH; Bergman, KA.
Treating preterm infants at risk for chronic lung disease with dexamethasone leads to an impaired quality of general movements.
Biol Neonate. 2002; 82(3):155-158
Doi: 10.1159/000063612
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- Co-Autor*innen der Med Uni Graz
- Pansy Jasmin
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- Abstract:
- Mortality rates do not decline markedly after postnatal corticosteroid therapy and concern has been raised about its neurological sequelae. We studied 37 preterm infants with Prechtl's method for the qualitative assessment of general movements before, during and after dexamethasone therapy and found that the quality of general movements was impaired in 9 of 13 initially normal infants (p = 0.004, McNemar test). The quality of fidgety movements at 3 months was abnormal in the majority of the infants and correlated strongly with neurological abnormalities at 2 years (Spearman r = 0.785, p < 0.001). Prechtl's method may prove useful for the early neurological evaluation of alternative corticosteroid treatment strategies for the treatment of chronic lung disease.
- Find related publications in this database (using NLM MeSH Indexing)
- Chronic Disease -
- Dexamethasone - adverse effects
- Echoencephalography - adverse effects
- Glucocorticoids - adverse effects
- Humans - adverse effects
- Infant, Newborn - adverse effects
- Infant, Premature - adverse effects
- Lung Diseases - prevention and control
- Movement Disorders - etiology
- Risk Factors - etiology
- Find related publications in this database (Keywords)
- corticosteroids
- infant
- preterm
- development
- general movements