Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

Logo MUG-Forschungsportal

Gewählte Publikation:

Haller, EM; Langmann, G; Langmann, A; Lerchner, H.
Persistence of Chlamydia trachomatis in patients with chronic therapy refractory conjunctivitis
Fortschr Ophthalmol. 1991; 88(3): 248-251. (- Case Report)
PubMed Google Scholar


Führende Autor*innen der Med Uni Graz
Haller-Schober Eva-Maria
Co-Autor*innen der Med Uni Graz
Langmann Andrea
Langmann Gerald

Dimensions Citations:

Plum Analytics:
We report three patients with recurrent Chlamydia-associated conjunctivitis. The clinical course of the Chlamydial infection was documented by positive conjunctival smears (direct immunofluorescence staining) and the evaluation of the IgA-titer in the sera (immunoperoxidase assay). The recovery of the ocular symptoms after therapy onset correlated well with the negative results of the conjunctival smears and the decrease in IgA level in the sera. The recurrence of the conjunctivitis was accompanied by an increase in the IgA titer in the sera of all three patients and the presence of Chlamydial elementary bodies in the conjunctival scrapings in two cases. Three patients showed immunologic pecularities: two had an allergic diathesis; the third patient developed Wegener disease 3 months after the onset of ocular inflammation. Inclusion bodies or Chlamydial DNA can persist in conjunctival cells. Anderson suggested that a recurrence of active Chlamydial infection may be induced by external causes, which lead to reconstitution of elementary bodies from the persisting DNA. The extraordinary immune situation of our patients might be one cause of the recurrent conjunctivitis.
Find related publications in this database (using NLM MeSH Indexing)
Adult -
Chlamydia trachomatis - drug effects
Conjunctiva - microbiology
Conjunctivitis, Inclusion - drug therapy
Drug Therapy, Combination - therapeutic use
English Abstract - therapeutic use
Erythromycin - administration and dosage
Female - administration and dosage
Follow-Up Studies - administration and dosage
Humans - administration and dosage
Infant, Newborn - administration and dosage
Male - administration and dosage
Middle Aged - administration and dosage
Recurrence - administration and dosage
Tetracycline - administration and dosage

© Med Uni Graz Impressum