Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Gewählte Publikation:

Rosen, AC; Sevelda, P; Klein, M; Graf, AH; Lahousen, M; Reiner, A; Auerbach, L; Vavra, N; Rosen, HR.
A comparative analysis of management and prognosis in stage I and II fallopian tube carcinoma and epithelial ovarian cancer.
Br J Cancer. 1994; 69(3):577-579 [OPEN ACCESS]
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Autor/innen der Med Uni Graz:
Lahousen Manfred
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Abstract:
Staging and surgical as well as post-operative treatment of primary Fallopian tube carcinoma (FTC) followed the lines established for primary ovarian cancer (OC). In a nationwide retrospective analysis we were able to find a distinct difference between these two tumours. A total of 262 patients, 68 with FTC and 194 with OC, in stage I and II were included into this study. A univariate as well as a multivariate analysis for survival was performed, including factors such as age, histological type, grading and surgical and adjuvant treatment. A significantly poorer outcome (P = 0.0002) for FTC patients with a 5-year survival of 50.8% compared with 77.5% for OC patients was observed. This finding was persistent and independent of any investigated factor, in univariate as well as multivariate analyses. Therefore, we feel that a more aggressive therapeutic approach to the treatment of FTC even in early stages can be recommended. On the other hand, the retrospective character of our study has to be taken into account.
Find related publications in this database (using NLM MeSH Indexing)
Age Factors -
Analysis of Variance -
Fallopian Tube Neoplasms - mortality
Female - mortality
Follow-Up Studies - mortality
Humans - mortality
Multivariate Analysis - mortality
Neoplasm Staging - mortality
Ovarian Neoplasms - mortality
Probability - mortality
Prognosis - mortality
Regression Analysis - mortality
Retrospective Studies - mortality
Survival Analysis - mortality
Survival Rate - mortality
Time Factors - mortality
Treatment Outcome - mortality

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