Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Gewählte Publikation:

Rosen, AC; Ausch, C; Hafner, E; Klein, M; Lahousen, M; Graf, AH; Reiner, A.
A 15-year overview of management and prognosis in primary fallopian tube carcinoma. Austrian Cooperative Study Group for Fallopian Tube Carcinoma.
Eur J Cancer. 1998; 34(11):1725-1729
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Autor/innen der Med Uni Graz:
Lahousen Manfred
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Abstract:
143 women treated in 28 departments from 1980 to 1995 were retrospectively analysed to study the impact of prognostic factors in primary carcinoma of the fallopian tube. The mean age of the patients was 62.5 years. Sixty (42%) tumours were FIGO stage I, 28 (20%) stage II, 38 (27%) stage III, 17 (12%) stage IV. Complete radical resection was achieved in 102 (71%) patients. In 122 (85%) women, surgery involved removal of the uterus, the adnexa, and/or the omentum or lymph nodes. Postoperative therapy consisted of either irradiation (n = 40; 28%) or chemotherapy (n = 70; 49%); 33 women (23%) did not receive any treatment after surgery. The 5-year survival rate for all cases was 43%. The 5-year survival rate was 59% for stages I and II and 19% for stages III and IV (P < 0.00001). FIGO stage, histological grade and presence of residual tumour had an independent prognostic impact in multivariate analysis. In order to investigate the role of p53 in primary fallopian tube carcinomas, we analysed the immunohistochemical expression of p53 protein regarding survival and FIGO stage in 63 patients (44%). No statistical significance was observed.
Find related publications in this database (using NLM MeSH Indexing)
Adult -
Aged -
Aged, 80 and over -
Combined Modality Therapy -
Fallopian Tube Neoplasms - drug therapy
Female - drug therapy
Gynecologic Surgical Procedures - statistics and numerical data
Humans - statistics and numerical data
Middle Aged - statistics and numerical data
Neoplasm Staging - statistics and numerical data
Postoperative Care - statistics and numerical data
Prognosis - statistics and numerical data
Retrospective Studies - statistics and numerical data
Survival Analysis - statistics and numerical data
Treatment Outcome - statistics and numerical data
Tumor Suppressor Protein p53 - metabolism

Find related publications in this database (Keywords)
Primary Fallopian Tube Carcinoma
Prognostic Factors
Postoperative Therapy
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