Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

Logo MUG-Forschungsportal

Gewählte Publikation:

SHR Neuro Krebs Kardio Lipid Stoffw Microb

Kahn, J; Rehak, P; Schweiger, M; Wasler, A; Wascher, T; Tscheliessnigg, KH; Müller, H.
The impact of overweight on the development of diabetes after heart transplantation.
Clin Transplant. 2006; 20(1):62-66 Doi: 10.1111/j.1399-0012.2005.00441.x
Web of Science PubMed FullText FullText_MUG Google Scholar


Führende Autor*innen der Med Uni Graz
Kahn Judith
Co-Autor*innen der Med Uni Graz
Müller Helmut
Rehak Peter
Schweiger Martin
Tscheliessnigg Karlheinz
Wascher Thomas
Wasler Andrae

Dimensions Citations:

Plum Analytics:

Scite (citation analytics):

Background: Overweight is defined with a body mass index (BMI) > 25. A BMI > 25 is known as an independent risk factor for increased morbidity and mortality. The influence of an increased BMI on the development of diabetes and on survival after heart transplantation (HTX) was investigated. Methods: A total of 137 patients (116 men, 21 women), who underwent HTX at our Department from 1986 to 2002, were included in the study. For group stratification, the pre-operative BMI values were taken (group I: BMI <= 25; group II: BMI > 25). Groups were compared for primary disease, age and sex, development of renal failure, development of diabetes, and survival. The probability of survival and the freedom-from-diabetes interval were calculated by the use of Kaplan-Meier method. Results: No significant differences between groups I and II were found concerning primary disease, age and sex, and occurrence of renal failure. There was a tendency towards increased survival (p = 0.18) in group I. Patients of group II developed diabetes after HTX more frequently than those of group I (p < 0.001). Cox regression revealed that pre-operative BMI > 25 is a highly significant independent risk factor for post-operative development of diabetes mellitus (DM) (p < 0.001). Conclusion: Overweight prior to HTX appears to negatively influence long-term survival after HTX, although this difference did not reach statistical significance. Pre-operative overweight is a significant and independent risk factor for the development of post-transplant diabetes.
Find related publications in this database (using NLM MeSH Indexing)
Adult -
Body Mass Index -
Body Weight -
Diabetes Mellitus - epidemiology
Diabetic Angiopathies - epidemiology
Female -
Heart Transplantation - mortality
Humans -
Male -
Middle Aged -
Postoperative Complications - epidemiology
Risk Factors -
Survival Analysis -

Find related publications in this database (Keywords)
body mass index
diabetes mellitus
heart transplantation
© Med Uni Graz Impressum