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SHR Neuro Krebs Kardio Lipid Stoffw Microb

Tatzber, F; Zelzer, S; Obermayer-Pietsch, B; Rinnerhofer, S; Kundi, M; Cvirn, G; Wultsch, G; Herrmann, M; Mangge, H; Niedrist, T; Wonisch, W.
Occupational Health Aspects with Special Focus on Physiological Differences between Office and Metalworkers.
Antioxidants (Basel). 2022; 11(4): Doi: 10.3390/antiox11040633 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG


Führende Autor*innen der Med Uni Graz
Tatzber Franz
Wonisch Willibald
Co-Autor*innen der Med Uni Graz
Cvirn Gerhard
Herrmann Markus
Mangge Harald
Niedrist Tobias
Obermayer-Pietsch Barbara
Wultsch Georg
Zelzer Sieglinde

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Physical workload adversely impacts inflammation, oxidative stress and mood in heavy workers. We compared these risk parameters between metalworkers (n = 20) and office workers (n = 30), including gender differences. Blood samples were analyzed with thirty parameters to overview endocrinology, inflammation, and psychological and oxidative stress. Despite an adequate antioxidative supply, oxidative stress occurred in metalworkers, as indicated by significantly increased peroxide and homocysteine (Hcy) levels. Moreover, increased concentrations were observed in this group regarding psychological stress and diet-related parameters. Sex-specific differences were determined for physical dimensions, dehydroepiandrosterone sulfate (DHEAS), Hcy, uric acid, triglycerides, osmolality, anti-Mullerian hormone (AMH) and testosterone. Age-associated differences were observed for DHEAS, glycosylated hemoglobin, adrenaline, AMH and testosterone. In male office workers, the body mass index was associated with increased LDL-HDL, cholesterol-HDL and homeostatic model assessment of insulin resistance (HOMA-IR). In conclusion, these results indicate increased oxidative stress and psychological stress in heavy workers independently of adequate antioxidant sustenance. The sedentary occupation of office workers, in turn, favored diseases of affluence. This might be particularly relevant for long-term occupied persons and older workers due to a hormonal shift coming along, given the risk for oxidative stress-related diseases such as cardiovascular disease, particularly in the case of males, based on their lifestyle habits.

Find related publications in this database (Keywords)
oxidative stress
sex-specific differences
taxing work
white-collar worker
blue-collar worker
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