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SHR Neuro Krebs Kardio Lipid Stoffw Microb

Reininghaus, B; Dalkner, N; Schörkhuber, C; Fleischmann, E; Fellendorf, FT; Ratzenhofer, M; Maget, A; Platzer, M; Bengesser, SA; Tmava-Berisha, A; Lenger, M; Queissner, R; Schönthaler, EMD; Reininghaus, EZ.
Nutrition, Overweight, and Cognition in Euthymic Bipolar Individuals Compared to Healthy Controls.
Nutrients. 2022; 14(6): Doi: 10.3390/nu14061176 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG


Führende Autor*innen der Med Uni Graz
Dalkner Nina
Reininghaus Bernd
Co-Autor*innen der Med Uni Graz
Bengesser Susanne
Fellendorf Frederike
Fleischmann Eva
Lenger Melanie
Maget Alexander
Platzer Martina
Queissner Robert
Reininghaus Eva
Schönthaler Elena
Tmava-Berisha Adelina

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Bipolar disorder (BD) is associated with impairments in cognitive functions, in which metabolic factors, e.g., overweight, seem to play a significant role. The aim of this study was to investigate the association between nutritional factors and cognitive performance in euthymic individuals with BD. A study cohort of 56 euthymic individuals with BD was compared to a sample of 53 mentally healthy controls. To assess cognitive function, the following tests were applied: California Verbal Learning Test, Trail Making Test A/B, d2 Test of Attention-Revised, and Stroop's Color-Word Interference Test. Furthermore, a 4-day food record was processed to evaluate dietary intake of macronutrients, specific micronutrients, and food diversity. Body mass index and waist to height ratio were calculated to assess overweight and central obesity. Results showed no nutritional differences between individuals with BD and controls. Individuals with BD performed worse in the d2 test than controls. Hierarchical regression analyses yielded no association between cognitive and nutritional parameters. However, waist to height ratio was negatively correlated with almost all cognitive tests. Central obesity seems to affect cognitive functioning in BD, while the lack of finding differences in nutritional data might be due to problems when collecting data and the small sample size. Consequently, further studies focusing on objectively measuring food intake with adequate sample size are needed.

Find related publications in this database (Keywords)
bipolar disorder
cognitive function
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