Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Janek, E; Edl, D; Taflinski, A; Talakic, E; Adelsmayr, G; Janisch, M; Igrec, J; Quehenberger, F; Fuchsjäger, M; Schöllnast, H.
Contrast media dose adjustment to allometric parameters of body mass in multiphasic CT of the liver: A comparison of different metrics.
Eur J Radiol. 2021; 141:109778
Doi: 10.1016/j.ejrad.2021.109778
Web of Science
PubMed
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FullText_MUG
- Führende Autor*innen der Med Uni Graz
- Fuchsjäger Michael
- Janek Elmar
- Co-Autor*innen der Med Uni Graz
- Adelsmayr Gabriel
- Igrec Jasminka
- Janisch Michael August Johann
- Quehenberger Franz
- Schoellnast Helmut
- Talakic Emina
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- Abstract:
- PURPOSE: To assess correlations of lean body weight (LBW) calculated with various formulas, total body weight (TBW), body height (BH), body mass index (BMI), body surface area (BSA) and fat-free mass (FFM) with vascular and parenchymal enhancement in multiphasic CT of the liver. METHOD: Thirty consecutive patients underwent multiphasic CT of the liver using constant iodine dose and flow rate. Contrast enhancement of aorta, portal vein and liver was calculated by measuring mean vascular and parenchymal attenuation in pre-contrast and post-contrast phases. Correlations of TBW, BH, BMI, BSA, FFM, and LBW (calculated with formulas of Boer, Hume, James and Green&Duffull) with enhancement were tested using Spearman's correlation coefficient. The method of Fieller et al. was used to calculate 95 % confidence intervals. A p-value ≤ 0.05 was considered statistically significant. RESULTS: Aortal enhancement correlated strongly with TBW, BSA, LBWBoer and LBWHume and moderately with BH, BMI, FFM, LBWJames and LBWGreen&Duffull. Liver enhancement in the late arterial phase correlated moderately with TBW, FFM, LBWBoer, LBWHume and LBWGreen&Duffull and weakly with BSA. Liver enhancement in the portal venous phase correlated strongly with TBW, BSA, FFM, LBWBoer, LBWHume and LBWGreen&Duffull, whereby overlap of the 95 % CI graphs demonstrated that the differences in the correlation coefficients were not statistically significant. Liver enhancement in the delayed phase correlated moderately with BH but did not correlate significantly with any other parameter. CONCLUSION: Regardless of the form used for calculation, LBW did not correlate statistically significantly stronger than TBW with vascular or parenchymal enhancement of the liver.
- Find related publications in this database (using NLM MeSH Indexing)
- Benchmarking - administration & dosage
- Body Weight - administration & dosage
- Contrast Media - administration & dosage
- Humans - administration & dosage
- Liver - diagnostic imaging
- Tomography, X-Ray Computed - administration & dosage
- Find related publications in this database (Keywords)
- Computed tomography
- CT
- Liver
- Allometry
- Contrast material