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Stiegler, P; Bausys, A; Leber, B; Strupas, K; Schemmer, P.
Impact of Melatonin in Solid Organ Transplantation-Is It Time for Clinical Trials? A Comprehensive Review.
Int J Mol Sci. 2018; 19(11): Doi: 10.3390/ijms19113509 [OPEN ACCESS]
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Führende Autor*innen der Med Uni Graz
Schemmer Peter
Stiegler Philipp
Co-Autor*innen der Med Uni Graz
Leber Bettina

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Solid organ transplantation is the "gold standard" for patients with end-stage organ disease. However, the supply of donor organs is critical, with an increased organ shortage over the last few years resulting in a significant mortality of patients on waiting lists. New strategies to overcome the shortage of organs are urgently needed. Some experimental studies focus on melatonin to improve the donor pool and to protect the graft; however, current research has not reached the clinical level. Therefore, this review provides a comprehensive overview of the data available, indicating that clinical evaluation is warranted.
Find related publications in this database (using NLM MeSH Indexing)
Graft Rejection - drug therapy
Graft Rejection - pathology
Humans -
Melatonin - therapeutic use
Organ Transplantation - trends
Time Factors -
Tissue Donors -
Tissue and Organ Procurement - trends
Waiting Lists -

Find related publications in this database (Keywords)
heart transplantation
lung transplantation
liver transplantation
kidney transplantation
pancreas transplantation
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