Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Seles, M; Hutterer, GC; Kiesslich, T; Pummer, K; Berindan-Neagoe, I; Perakis, S; Schwarzenbacher, D; Stotz, M; Gerger, A; Pichler, M.
Current Insights into Long Non-Coding RNAs in Renal Cell Carcinoma.
Int J Mol Sci. 2016; 17(4):573-573
Doi: 10.3390/ijms17040573
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- Führende Autor*innen der Med Uni Graz
- Hutterer Georg
- Seles Maximilian
- Co-Autor*innen der Med Uni Graz
- Gerger Armin
- Hasenleithner Samantha
- Ninaus Daniela
- Pichler Martin
- Pummer Karl
- Stotz Michael
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- Abstract:
- Renal cell carcinoma (RCC) represents a deadly disease with rising mortality despite intensive therapeutic efforts. It comprises several subtypes in terms of distinct histopathological features and different clinical presentations. Long non-coding RNAs (lncRNAs) are non-protein-coding transcripts in the genome which vary in expression levels and length and perform diverse functions. They are involved in the inititation, evolution and progression of primary cancer, as well as in the development and spread of metastases. Recently, several lncRNAs were described in RCC. This review emphasises the rising importance of lncRNAs in RCC. Moreover, it provides an outlook on their therapeutic potential in the future.
- Find related publications in this database (using NLM MeSH Indexing)
- Animals -
- Carcinoma, Renal Cell - genetics
- Carcinoma, Renal Cell - pathology
- Gene Expression Regulation, Neoplastic -
- Humans -
- Kidney - pathology
- Kidney Neoplasms - genetics
- Kidney Neoplasms - pathology
- Neoplasm Metastasis - genetics
- Neoplasm Metastasis - pathology
- RNA, Long Noncoding - genetics
- Find related publications in this database (Keywords)
- renal cell cancer-carcinoma
- long non-coding RNAs
- metastases