Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Reininghaus, B; Bengesser, SA; Reininghaus, E; Lackner, N; Kapfhammer, HP; Birner, A.
[Rapid cycling--finally stable but obese--target acquired?].
Fortschr Neurol Psychiatr. 2014; 82(12):701-705
Doi: 10.1055/s-0034-1385566
(- Case Report)
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- Führende Autor*innen der Med Uni Graz
- Birner Armin
- Reininghaus Bernd
- Co-Autor*innen der Med Uni Graz
- Bengesser Susanne
- Dalkner Nina
- Kapfhammer Hans-Peter
- Reininghaus Eva
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- Abstract:
- Overweight and obesity are common in patients with bipolar disorder. Rates of up to 70% are described in scientific publications. There is sufficient evidence that these conditions are associated with a worse course of the disease (more episodes, higher suicide and hospitality rates, worse response to lithium, somatic comorbidities). Most of the mood stabilisers lead to weight gain. This is also true for clozapine, which can be effective in therapy-refractory courses of bipolar disorder. This case report demonstrates the complexity of the treatment of bipolar disorder. A young patient in depressive stupor following a severe suicide attempt after 5 months of hospital treatment was sent to our department to perform ECT. This was not possible because of the severity of his injuries. We were able to cure the acute condition and interrupt the course of rapid cycling with a combination of clomipramine, lithium and clozapine. A stable course of four years under this medication and psychoeducation has been achieved. In this period the patient was able to lower his body mass index from 38 to 26 because of a consequent lifestyle modification. © Georg Thieme Verlag KG Stuttgart · New York.
- Find related publications in this database (using NLM MeSH Indexing)
- Antimanic Agents - adverse effects
- Antimanic Agents - therapeutic use
- Antipsychotic Agents - adverse effects
- Antipsychotic Agents - therapeutic use
- Bipolar Disorder - complications
- Bipolar Disorder - drug therapy
- Bipolar Disorder - therapy
- Clozapine - adverse effects
- Clozapine - therapeutic use
- Humans -
- Male -
- Obesity - complications
- Obesity - therapy
- Overweight - complications
- Overweight - therapy
- Suicide, Attempted -
- Young Adult -
- Find related publications in this database (Keywords)
- bipolar disorder
- obesity
- therapy-refractory
- lifestyle
- clozapine