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Schwaberger, B; Pichler, G; Binder, C; Avian, A; Pocivalnik, M; Urlesberger, B.
Even mild respiratory distress alters tissue oxygenation significantly in preterm infants during neonatal transition.
Physiol Meas. 2014; 35(10):2085-2099 Doi: 10.1088/0967-3334/35/10/2085
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Führende Autor*innen der Med Uni Graz
Schwaberger Bernhard Christian
Co-Autor*innen der Med Uni Graz
Avian Alexander
Binder-Heschl Corinna
Pichler Gerhard
Ribitsch Mirjam
Urlesberger Berndt

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Near-infrared spectroscopy (NIRS) enables continuous non-invasive measurements of regional oxygen saturation (rSO2). The aim was to evaluate the dynamics of rSO2 of the brain, preductal and postductal tissues during postnatal transition in preterm infants with and without respiratory support (RS). This single-centre study was designed as an exploratory prospective observational study. Fifty one preterm infants (≥ 30 + 0 and < 37 + 0 weeks) delivered by caesarean section were included. RS using a T-Piece-Resuscitator and supplemental oxygen were given according to guidelines. NIRS measurements were carried out by using Invos Monitor (Covidien; USA) for the first 15 min of life. Three NIRS transducers were attached on the forehead (rSO2brain), the right forearm (rSO2arm) and the left lower leg (rSO2leg). Two groups were compared based on need for RS: normal transition (NT) and RS group. In NT group rSO2brain increased over time and was significantly higher than rSO2arm, whereas in RS group rSO2brain and rSO2arm increased without significant differences. Courses of rSO2arm and rSO2leg increased over time and showed a converging pattern with initially lower values of rSO2leg in NT group and a diverging pattern with lower levels of rSO2leg in RS group. Overall, rSO2 levels were higher in NT compared to RS group. Our findings indicate that the decreased rSO2 levels in RS group compared to NT group are not only caused by lower arterial oxygen saturation levels, but also by a compromised perfusion even in infants with only mild respiratory distress.
Find related publications in this database (using NLM MeSH Indexing)
Brain - metabolism
Ductus Arteriosus - metabolism
Dyspnea - metabolism
Dyspnea - physiopathology
Female -
Heart Rate -
Humans -
Infant, Newborn -
Infant, Premature - metabolism
Infant, Premature - physiology
Male -
Muscles - metabolism
Oxygen - metabolism
Respiration -
Spectroscopy, Near-Infrared -

Find related publications in this database (Keywords)
near-infrared spectroscopy
cerebral regional oxygen saturation
preductal oxygen saturation
postductal regional oxygen saturation
respiratory support
transition period
postnatal transition
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