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Mian, QN; Pichler, G; Binder, C; O'Reilly, M; Aziz, K; Urlesberger, B; Cheung, PY; Schmölzer, GM.
Tidal volumes in spontaneously breathing preterm infants supported with continuous positive airway pressure.
J Pediatr. 2014; 165(4):702-706 Doi: 10.1016/j.jpeds.2014.06.047
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Co-Autor*innen der Med Uni Graz
Binder-Heschl Corinna
Pichler Gerhard
Schmölzer Georg
Urlesberger Berndt

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To describe changes in tidal volume (VT) and their correlation to changes in oxygen saturation and heart rate in spontaneously breathing preterm infants immediately after birth. In this prospective observational, 2-center study, a flow sensor was attached to the facemask of spontaneously breathing infants born at <37 weeks' gestational age who received continuous positive airway pressure (CPAP) immediately after birth. Respiratory function, heart rate, and oxygen saturation were continuously recorded during spontaneous breathing. Fifty-five infants (mean [SD] gestational age 31 [26-36] weeks and birth weight 1647 [500] g) received mask CPAP in the delivery room. CPAP was started at a median (IQR) 90 (60-118) seconds after birth and was delivered for 720 (300-900) seconds. Median VT ranged between 4.2 and 5.8 mL/kg with the individual VT varied between 0.9 and 19.8 mL/kg. Overall, VT increased over the first few minutes after birth and decreased thereafter. The increase in saturation after birth lagged behind the published normal ranges for spontaneously breathing preterm infants without CPAP. The 50th percentile for spontaneous VT in preterm infants during mask CPAP ranged from 4.2 to 5.8 mL/kg, with wide individual variation observed in the first minutes after birth. Preterm infants requiring CPAP after birth may take longer to achieve so-called "normal" saturation targets. Copyright © 2014 Elsevier Inc. All rights reserved.
Find related publications in this database (using NLM MeSH Indexing)
Continuous Positive Airway Pressure - methods
Female -
Heart Rate -
Humans -
Infant -
Infant, Newborn -
Infant, Premature -
Male -
Masks -
Monitoring, Physiologic -
Oxygen - blood
Oxygen - therapeutic use
Prospective Studies -
Respiration -
Tidal Volume - physiology
Time Factors -
Treatment Outcome -

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