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Reininghaus, EZ; Zelzer, S; Reininghaus, B; Lackner, N; Birner, A; Bengesser, SA; Fellendorf, FT; Kapfhammer, HP; Mangge, H.
[Oxidative stress in bipolar affective disorder].
Nervenarzt. 2014; 85(9):1099-1107
Doi: 10.1007/s00115-013-3962-x
Web of Science
PubMed
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- Führende Autor*innen der Med Uni Graz
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Reininghaus Eva
- Co-Autor*innen der Med Uni Graz
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Bengesser Susanne
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Birner Armin
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Dalkner Nina
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Fellendorf Frederike
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Kapfhammer Hans-Peter
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Mangge Harald
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Reininghaus Bernd
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Zelzer Sieglinde
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- Abstract:
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The results of mortality studies have indicated that medical conditions, such as cardiovascular disease, obesity and diabetes are the most important causes of mortality among patients with bipolar disorder. The reasons for the increased incidence and mortality are not fully understood. Oxidative stress and an inadequate antioxidative system might be one missing link and could also help to further elucidate the pathophysiological basis of bipolar disorder. This article provides a comprehensive review of oxidative stress in general and about the existing data for bipolar disorder. In addition information is given about possible therapeutic strategies to reduce oxidative stress and the use in bipolar disorder.
- Find related publications in this database (using NLM MeSH Indexing)
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Bipolar Disorder - immunology
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Cytokines - immunology
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Humans -
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Models, Immunological -
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Oxidative Stress - immunology
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Reactive Oxygen Species - immunology
- Find related publications in this database (Keywords)
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Oxidative stress
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Bipolar affective disorder
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Antioxidant system
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Reactive oxygen species
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Lifestyle