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SHR Neuro Krebs Kardio Lipid Stoffw Microb

Reininghaus, EZ; Zelzer, S; Reininghaus, B; Lackner, N; Birner, A; Bengesser, SA; Fellendorf, FT; Kapfhammer, HP; Mangge, H.
[Oxidative stress in bipolar affective disorder].
Nervenarzt. 2014; 85(9):1099-1107 Doi: 10.1007/s00115-013-3962-x
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Führende Autor*innen der Med Uni Graz
Reininghaus Eva
Co-Autor*innen der Med Uni Graz
Bengesser Susanne
Birner Armin
Dalkner Nina
Fellendorf Frederike
Kapfhammer Hans-Peter
Mangge Harald
Reininghaus Bernd
Zelzer Sieglinde

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The results of mortality studies have indicated that medical conditions, such as cardiovascular disease, obesity and diabetes are the most important causes of mortality among patients with bipolar disorder. The reasons for the increased incidence and mortality are not fully understood. Oxidative stress and an inadequate antioxidative system might be one missing link and could also help to further elucidate the pathophysiological basis of bipolar disorder. This article provides a comprehensive review of oxidative stress in general and about the existing data for bipolar disorder. In addition information is given about possible therapeutic strategies to reduce oxidative stress and the use in bipolar disorder.
Find related publications in this database (using NLM MeSH Indexing)
Bipolar Disorder - immunology
Cytokines - immunology
Humans -
Models, Immunological -
Oxidative Stress - immunology
Reactive Oxygen Species - immunology

Find related publications in this database (Keywords)
Oxidative stress
Bipolar affective disorder
Antioxidant system
Reactive oxygen species
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