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SHR Neuro Krebs Kardio Lipid Stoffw Microb

Jahn, S; Zollner, G; Lackner, C; Stauber, RE.
Severe toxic hepatitis associated with dronedarone.
Curr Drug Saf. 2013; 8(3):201-202 Doi: 10.2174/15748863113089990031 (- Case Report)
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Führende Autor*innen der Med Uni Graz
Jahn Stephan
Stauber Rudolf
Co-Autor*innen der Med Uni Graz
Lackner Karoline
Zollner Gernot

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Dronedarone was introduced in 2009 as a new antiarrhythmic agent and since then has been increasingly prescribed in atrial fibrillation or flutter. To date, two cases of severe toxic hepatitis have been reported in patients treated with dronedarone, both requiring emergency liver transplantation, and the FDA as well as the EMA have issued warnings about possible severe hepatotoxicity of dronedarone. Here we report an additional case of toxic hepatitis associated with dronedarone presenting with acute liver failure, followed by spontaneous recovery, in a 69-year old woman.
Find related publications in this database (using NLM MeSH Indexing)
Aged -
Amiodarone - adverse effects Amiodarone - analogs & derivatives Amiodarone - therapeutic use
Anti-Arrhythmia Agents - adverse effects Anti-Arrhythmia Agents - therapeutic use
Atrial Fibrillation - drug therapy
Drug-Induced Liver Injury, Chronic - etiology Drug-Induced Liver Injury, Chronic - physiopathology
Female -
Humans -
Severity of Illness Index -

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