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Pichler, G; Avian, A; Binder, C; Zotter, H; Schmölzer, GM; Morris, N; Müller, W; Urlesberger, B.
aEEG and NIRS during transition and resuscitation after birth: promising additional tools; an observational study.
Resuscitation. 2013; 84(7):974-978 Doi: 10.1016/j.resuscitation.2012.12.025
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Führende Autor*innen der Med Uni Graz
Pichler Gerhard
Co-Autor*innen der Med Uni Graz
Avian Alexander
Binder-Heschl Corinna
Morris Nicholas Mark
Müller Wilhelm
Schmölzer Georg
Urlesberger Berndt
Zotter Heinz

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Aim of the study: During resuscitation no routine cerebral monitoring is available. We aimed at monitoring cerebral activity and oxygenation continuously during neonatal transition and resuscitation. Methods: Neonates >= 34 weeks of gestation born via cesarean section were included. Cerebral activity was continuously measured with amplitude-integrated-EEG (aEEG) and cerebral oxygenation (rSO(2)) with near-infrared-spectroscopy (NIRS) during the first 10 min after birth. For quantitative analysis of aEEG every minute the mean minimum amplitude (V-min) and maximum amplitude (V-max) was determined. Uncompromised neonates were compared to neonates in need of resuscitation. Results: Out of 224 eligible neonates 31 uncompromised and 15 in need of respiratory support were included. Uncompromised neonates showed higher values for V-min in the third minute and higher values for V-max in the third and fourth minute compared to the tenth minute post-partum. In uncompromised neonates rSO(2) values during the first 6 min after birth were lower compared to minute ten. Neonates in need of respiratory support had lower rSO(2) values over the first 8 min after birth compared to minute ten. Conclusions: This is the first study demonstrating that monitoring of aEEG and NIRS to measure cerebral activity and oxygenation during immediate postpartum transition is feasible. During transition compromised neonates requiring resuscitation showed a different cerebral activity pattern compared to uncompromised neonates. (C) 2013 Elsevier Ireland Ltd. All rights reserved.
Find related publications in this database (using NLM MeSH Indexing)
Brain - blood supply
Cerebrovascular Circulation - physiology
Cesarean Section -
Electroencephalography -
Female -
Humans -
Infant, Newborn -
Male -
Monitoring, Physiologic - methods
Oxygen - blood
Oxygen Inhalation Therapy -
Prospective Studies -
Respiratory Distress Syndrome, Newborn - therapy
Spectroscopy, Near-Infrared -

Find related publications in this database (Keywords)
Amplitude integrated electroencephalography
Near infrared spectroscopy
Neonatal transition
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