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SHR Neuro Krebs Kardio Lipid Stoffw Microb

Urlesberger, B; Grossauer, K; Pocivalnik, M; Avian, A; Müller, W; Pichler, G.
Regional oxygen saturation of the brain and peripheral tissue during birth transition of term infants.
J Pediatr. 2010; 157(5): 740-744. Doi: 10.1016/j.jpeds.2010.05.013
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Führende Autor*innen der Med Uni Graz
Urlesberger Berndt
Co-Autor*innen der Med Uni Graz
Avian Alexander
Großauer Karin
Müller Wilhelm
Pichler Gerhard
Ribitsch Mirjam

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Objective To evaluate regional tissue oxygenation of the brain and preductal and postductal peripheral (muscle) tissue during immediate transition after birth, and to correlate with peripheral preductal and postductal arterial oxygen saturation. Study design We conducted a prospective observational study. With near-infrared spectroscopy (NIRS), changes in regional oxygen saturation of the brain (rSO2brain), peripheral preductal tissue (rSO2pre), and peripheral postductal tissue (rSO2post) were measured during the first 10 minutes of life in 59 healthy term infants after elective caesarean delivery. Fractional tissue oxygen extraction was calculated for all 3 regions. Results Mean rSO2brain increased rapidly from 44% (3 minutes) to 76% (7 minutes); thereafter no significant change occurred. Mean rSO2pre and rSO2post increased constantly from minute 3 to minute 10, from 36%(pre)/27%(post) to 66%(pre)/58%(post). Fractional tissue oxygen extraction decreased in all 3 regions during the first minutes of life. Fractional tissue oxygen extraction of the brain did not change significantly after 5 minutes, and preductal and postductal fractional tissue oxygen extraction did not change significantly after 8 minutes. Conclusions During transition, the brain had the highest saturation levels, indicating a preference of oxygen delivery to the brain. Fractional tissue oxygen extraction of the brain reached a plateau earlier compared with peripheral tissue. (J Pediatr 2010; 157:740-4).
Find related publications in this database (using NLM MeSH Indexing)
Brain - metabolism
Female -
Humans -
Infant, Newborn -
Male -
Muscles - metabolism
Oxygen - metabolism
Prospective Studies -
Term Birth -

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