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Haas, AM; Ahmed, D; Stattin, M; Graf, A; Krepler, K; Ansari-Shahrezaei, S.
Comparison of macular neovascularization lesion size by the use of Spectral-Domain Optical Coherence Tomography Angiography and Swept-Source Optical Coherence Tomography Angiography versus Indocyanine Green Angiography
ACTA OPHTHALMOL. 2020;
Web of Science PubMed FullText FullText_MUG

 

Autor/innen der Med Uni Graz:
Ansari Shahrezaei Siamak
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Abstract:
Purpose To compare the lesion sizes of macular neovascularization (MNV) imaged with spectral-domain (SD) and swept-source (SS) optical coherence tomography angiography (OCTA) as well as indocyanine green angiography (ICGA). Methods In this prospective, observational case series, patients showing a secured diagnosis of MNV on ICGA or Fluorescein Angiography, were imaged by SD-OCTA and SS-OCTA on the same day. Lesion size was measured on 3 x 3-mm(2)and 6 x 6-mm(2)scans using the Maestro 2 SD-OCTA (Topcon Corporation, Tokyo Japan) and the Triton SS-OCTA device (Topcon Corporation, Tokyo Japan) and compared to ICGA (Spectralis HRA, Heidelberg, Germany). Results Twenty eyes from 20 patients (11 females, 55%) were enrolled. The neovascularization area measured on 6 x 6-mm(2)SD-OCTA was lower compared to that outlined on SS-OCTA, however, not reaching statistical significance (p = 0.094). Regarding 3 x 3-mm(2)measurements, the median lesion sizes between the two OCTA devices were comparable (p = 0.492). Indocyanine green angiography depicted a larger lesion area than both OCTA devices, however, not reaching statistical significance. Conclusion SD-OCTA tends to show smaller areas of MNV extension than SS-OCTA regarding 6 x 6 mm(2)scans. The lesion size of MNV can be very well compared between the different devices, emphasizing the use of OCTA for monitoring neovascular area. Lesion measurements on SS-OCTA correlate better with ICGA than SD-OCTA.

Find related publications in this database (Keywords)
age-related macular degeneration
indocyanine green angiography
macular neovascularization
optical coherence tomography angiography
spectral-domain
swept-source
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