Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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SHR Neuro Krebs Kardio Lipid

Zalaudek, I; Conforti, C; Guarneri, F; Vezzoni, R; Deinlein, T; Hofmann-Wellenhof, R; Caterina Longo, R; Moscarella, E; Harald Kittler, E; Giuseppe Argenziano, E; Giuffrida, R.
Clinical and dermoscopic characteristics of congenital and non-congenital nevus-associated melanomas.
J Am Acad Dermatol. 2020;
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Autor/innen der Med Uni Graz:
Deinlein Teresa Maria
Hofmann-Wellenhof Rainer
Zalaudek Iris
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Abstract:
No specific features of nevus-associated melanoma (NAM) are currently defined. To identify clinical/dermoscopic features of NAM. Retrospective evaluation of histopathologically diagnosed NAM. 80/165 NAMs had a clinically recognizable nevus component, often raised or nodular, most frequently characterized by different morphologic clones and/or colors. In 111/165 NAMs, dermoscopy revealed a nevus component, prevalently characterized by regular dots/clods and structureless brown areas. Clinically, the melanoma component was eccentric/peripheral in 45/80 cases, central in 35/80; dermoscopically, the figures were 59/111 and 52/111, respectively. Melanomas associated with congenital nevi (C-NAMs) occur at younger age and have a thicker Breslow than melanomas associated with acquired nevi (NC-NAMs). Dermoscopically regular dots/globules characterize C-NAMs, hypopigmented structureless areas characterize NC-NAMs. Retrospective analysis. C-NAMs are oftener central to congenital nevus, with clod/globular or structureless brown pattern, typical of young patients. NC-NAMs are frequently hypopigmented nodules/plaques, eccentric/peripheral, with hypopigmented structureless areas, typical of elders. Copyright © 2020. Published by Elsevier Inc.

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