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SHR Neuro Krebs Kardio Lipid

Moser, O; Pandis, M; Aberer, F; Kojzar, H; Hochfellner, D; Elsayed, H; Motschnig, M; Augustin, T; Kreuzer, P; Pieber, TR; Sourij, H; Mader, JK.
A head-to-head comparison of personal and professional continuous glucose monitoring systems in people with type 1 diabetes: hypoglycaemia remains the weak spot.
Diabetes Obes Metab. 2018;
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Autor/innen der Med Uni Graz:
Aberer Felix
Elsayed Hesham
Hochfellner Daniel
Kojzar Harald
Mader Julia
Moser Othmar
Motschnig Melanie
Pandis Marlene
Pieber Thomas
Sourij Harald
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Abstract:
To compare the performance of a professional (proCGM) and a personal continuous glucose monitoring (persCGM) system worn in parallel under standardised conditions in individuals with type 1 diabetes (T1D). Two CGM systems (iPro2 - proCGM; Minimed 640G - persCGM) worn in parallel using the same sensor (Enlite 2) were compared. Ten people with T1D were included in this single-centre, open-label study in which CGM performance was evaluated. The study consisted of a 24-hour inpatient phase (meals, exercise, glycaemic challenges) and a 4-day home phase. Analyses included fulfilment of ISO 15197:2013 criteria, mean absolute relative difference (MARD), Parkes Error Grid and Bland-Altman plots. During the inpatient stay ISO 15197:2013 criteria fulfilment was 58.4% (proCGM) and 57.8% (persCGM). At home the systems met ISO 15197:2013 criteria by 66.5% (proCGM) and 65.3% (persCGM). No difference of MARD in inpatient phase (19.1±16.7% vs. 19.0±19.6; p=0.83) and home-phase (18.6±26.8% vs. 17.4±21.3%, p=0.87) was observed. All sensors performed less accurate during hypoglycaemia. ProCGM and persCGM showed similar performance during day- and night-time for the inpatient and the home-phase. However, sensor performance was reduced during hypoglycaemia for both systems. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

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