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SHR Neuro Krebs Kardio Lipid

Tschandl, P; Gambardella, A; Boespflug, A; Deinlein, T; de Giorgi, V; Kittler, H; Lallas, A; Malvehy, J; Moscarella, E; Puig, S; Scalvenzi, M; Thomas, L; Zalaudek, I; Alfano, R; Argenziano, G.
Seven Non-melanoma Features to Rule Out Facial Melanoma.
Acta Derm Venereol. 2017; 97(10):1219-1224 [OPEN ACCESS]
Web of Science PubMed FullText FullText_MUG

 

Autor/innen der Med Uni Graz:
Deinlein Teresa Maria
Zalaudek Iris
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Abstract:
Facial melanoma is difficult to diagnose and dermatoscopic features are often subtle. Dermatoscopic non-melanoma patterns may have a comparable diagnostic value. In this pilot study, facial lesions were collected retrospectively, resulting in a case set of 339 melanomas and 308 non-melanomas. Lesions were evaluated for the prevalence (> 50% of lesional surface) of 7 dermatoscopic non-melanoma features: scales, white follicles, erythema/reticular vessels, reticular and/or curved lines/fingerprints, structureless brown colour, sharp demarcation, and classic criteria of seborrhoeic keratosis. Melanomas had a lower number of non-melanoma patterns (p< 0.001). Scoring a lesion suspicious when no prevalent non-melanoma pattern is found resulted in a sensitivity of 88.5% and a specificity of 66.9% for the diagnosis of melanoma. Specificity was higher for solar lentigo (78.8%) and seborrhoeic keratosis (74.3%) and lower for actinic keratosis (61.4%) and lichenoid keratosis (25.6%). Evaluation of prevalent non-melanoma patterns can provide slightly lower sensitivity and higher specificity in detecting facial melanoma compared with already known malignant features.

Find related publications in this database (Keywords)
dermatoscopy
dermoscopy
face
melanoma
lentigo maligna
diagnosis
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