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Wöll, E; Eisterer, W; Gerger, A; Kühr, T; Prager, GW; Rumpold, H; Ulrich-Pur, H; Vogl, U; Winder, T; Weiss, L; Greil, R.
Treatment Algorithm for Patients With Gastric Adenocarcinoma: An Austrian Consensus on Systemic Therapy.
Anticancer Res. 2019; 39(9): 4589-4596. Doi: 10.21873/anticanres.13638 [OPEN ACCESS]
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Co-Autor*innen der Med Uni Graz

Gerger Armin

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Abstract:

Despite recent advances in the treatment of gastric cancer, mortality related to this disease is still substantial. Surgery and chemotherapy represent the cornerstones of patient management. Targeted treatments that include anti-angiogenic agents and the advent of immunotherapies can contribute to improved patient prognosis. Herein, we present an Austrian consensus on the systemic treatment of patients with gastric adenocarcinoma and lower gastroesophageal junction, including those with human epidermal growth factor receptor 2 (HER2)-positive disease. The consensus considers the curative setting, as well as first-line to late-line systemic treatment options in the palliative setting. For HER2-positive disease, first-line and second-line therapies are discussed, as well as HER2 testing. Potential future therapies are also listed, with a focus on anti-angiogenic treatments and checkpoint inhibition, that might provide a further step forward in the management of patients with gastric cancer. Copyright© 2019, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

Find related publications in this database (using NLM MeSH Indexing)

Adenocarcinoma - diagnosis

Adenocarcinoma - etiology

Adenocarcinoma - therapy

Algorithms -

Algorithms -

Combined Modality Therapy -

Consensus -

Disease Management -

Humans -

Stomach Neoplasms - diagnosis

Stomach Neoplasms - etiology

Stomach Neoplasms - therapy

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Gastric cancer

adenocarcinoma

stomach

lower gastroesophageal junction

treatment algorithm

review

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