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Perl, S; Niederl, E; Kos, C; Mrak, P; Ederer, H; Rakovac, I; Beck, P; Kraler, E; Stoff, I; Klima, G; Pieske, BM; Pieber, TR; Zweiker, R.
Randomized Evaluation of the Effectiveness of a Structured Educational Program for Patients With Essential Hypertension.
Am J Hypertens. 2016; 29(7):866-872 Doi: 10.1093/ajh/hpv186 [OPEN ACCESS]
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Führende Autor*innen der Med Uni Graz
Perl Sabine
Co-Autor*innen der Med Uni Graz
Kos Cornelia
Niederl Ella
Pieber Thomas
Pieske Burkert Mathias
Zweiker Robert

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Adherence to medication and lifestyle interventions are essential keys for the management of hypertension. In this respect, a structured educational program for hypertensive patients has got remarkable merits (herz.leben). In order to determine the isolated effect of participation in the educational program, neglecting the possible impact of more intense care, this prospective multicenter randomized controlled study was designed (NCT00453037). A total of 256 patients in 13 centers were enrolled and randomly assigned to 2 groups (G). G-I (n = 137) underwent the educational program immediately (T-0), G-II (n = 119) after 6 months (T-6). Follow-up visits were done after 6 (T-6) and 12 (T-12) months. Primary endpoint was a difference in office blood pressure (BP) at T-6, when only G-I had undergone the educational program. Patients' baseline characteristics were comparable. At T-6, systolic office and home BP were significantly lower in G-I compared to G-II: office BP systolic 139 (134-150) mm Hg vs. 150 (135-165) mm Hg (P < 0.01); diastolic 80 (76-85) mm Hg vs. 84 (75-90) mm Hg (ns); home BP systolic 133 (130-140) mm Hg vs. 142 (132-150) mm Hg (P < 0.01); diastolic 80 (75-85) mm Hg vs. 80 (76-89) mm Hg (ns)). At T-12, when all patients had undergone the educational program differences in BP disappeared. The results of this multicenter randomized controlled study provide significant evidence for benefit by participation in a structured educational program. Positive effects seem to be mediated by better adherence and life style changes due to higher levels of information and patient empowerment. Therefore, educational strategies should be considered as standard of care for hypertensive patients. © American Journal of Hypertension, Ltd 2015. All rights reserved. For Permissions, please email:
Find related publications in this database (using NLM MeSH Indexing)
Aged -
Disease Management -
Essential Hypertension - therapy
Female -
Humans -
Male -
Middle Aged -
Patient Education as Topic - methods
Program Evaluation -

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cardiovascular risk
educational program
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