Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
SHR Neuro Krebs Kardio Lipid Stoffw Microb
Smolle, M; Uranitsch, S; Gerger, A; Pichler, M; Haybaeck, J.
Current status of long non-coding RNAs in human cancer with specific focus on colorectal cancer.
Int J Mol Sci. 2014; 15(8):13993-14013
Doi: 10.3390/ijms150813993
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- Führende Autor*innen der Med Uni Graz
- Haybäck Johannes
- Smolle Maria Anna
- Co-Autor*innen der Med Uni Graz
- Gerger Armin
- Pichler Martin
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- Abstract:
- The latest investigations of long non-coding RNAs (lncRNAs) have revealed their important role in human cancers. LncRNAs are larger than 200 nucleotides in length and fulfill their cellular purpose without being translated into proteins. Though the molecular functions of some lncRNAs have been elucidated, there is still a high number of lncRNAs with unknown or controversial functions. In this review, we provide an overview of different lncRNAs and their role in human cancers. In particular, we emphasize their importance in tumorigenesis of colorectal cancer, the third most common cancer worldwide.
- Find related publications in this database (using NLM MeSH Indexing)
- Biomarkers, Tumor - metabolism
- Carcinoembryonic Antigen - metabolism
- Colorectal Neoplasms - drug therapy
- Humans -
- Neoplasm Staging -
- Neoplasms - genetics
- RNA, Long Noncoding - metabolism
- Find related publications in this database (Keywords)
- colorectal cancer
- lncRNA
- cancer
- molecular tumor pathogenesis