Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Lindner, E; Weinberger, A; Kirschkamp, T; El-Shabrawi, Y; Barounig, A.
Near-Infrared Autofluorescence and Indocyanine Green Angiography in Central Serous Chorioretinopathy
OPHTHALMOLOGICA. 2012; 227(1): 34-38.
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Autor/innen der Med Uni Graz:
El-Shabrawi Yosuf
Lindner Ewald
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Abstract:
Purpose: To evaluate the diagnostic potential of near-infrared (NIR) autofluorescence (AF) in central serous chorioretinopathy (CSC) and to present a method to analyze NIR-AF findings quantitatively. Procedures: NIR-AF images, indocyanine green (ICG) angiograms, blue-light autofluorescence (BL-AF) images and fluorescein angiograms were recorded with the use of a confocal scanning laser ophthalmoscope in 19 eyes of 17 patients with CSC. Gray-value ratios were calculated to compare the methods. Results: Using NIR-AF, hypofluorescent spots were observed at the leakage site in 18 of 19 eyes (94.7%). The mean gray-value ratio (+/- SD) was 0.55 +/- 0.22 for the site of the leakage point with NIR-AF and 0.65 +/- 0.35 with BL-AF. ICG angiography showed a gray-value ratio of 2.37 +/- 2.07. Fluorescein angiography had the best contrast, with a gray-value ratio of 13.44 +/- 15.02. Conclusion: NIR-AF demonstrated CSC in 94.7% of the cases. NIR-AF may be a noninvasive alternative to detect CSC. Copyright (C) 2011 S. Karger AG, Basel

Find related publications in this database (Keywords)
Chronic serous chorioretinopathy
Near-infrared autofluorescence
Indocyanine green angiography
Blue-light autofluorescence
Fluorescein angiography
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