Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Oliveira, A; Arzberger, E; Massone, C; Fink-Puches, R; Zalaudek, I; Hofmann-Wellenhof, R.
Dermoscopy, reflectance confocal microscopy and immunohistochemical analysis in melanocytic lesions with Meyerson's phenomenon.
Dermatology. 2014; 229(4):297-305 (- Case Report)
Web of Science PubMed FullText FullText_MUG

 

Autor/innen der Med Uni Graz:
Arzberger Edith Johanna
Fink-Puches Regina
Hofmann-Wellenhof Rainer
Massone Cesare
Zalaudek Iris
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Abstract:
Meyerson's phenomenon is characterized by a symmetrical halo of erythema and scale around central, mostly melanocytic lesions. Our aim was to describe the dermoscopic and reflectance confocal microscopy (RCM) features of melanocytic tumors less frequently associated with Meyerson's phenomenon, with histopathology and immunohistochemistry correlation. Clinical, dermoscopic and RCM images of 4 histopathologically confirmed melanocytic tumors associated with Meyerson's phenomenon (3 dysplastic compound nevi and 1 melanoma) were retrospectively collected, with additional immunohistochemical analysis. RCM showed in vivo features of both melanocytic and spongiotic nature of the lesion associated with Meyerson's phenomenon, even in cases with absent halo. Our study also supported the involvement of immune-mediated CD4+ T lymphocyte mechanisms and Langerhans cells. Our case series supports the potential of RCM in the evaluation of tumoral and inflammatory skin diseases. RCM features of rare Meyerson's melanoma were also described for the first time. © 2014 S. Karger AG, Basel.
Find related publications in this database (using NLM MeSH Indexing)
Aged -
Antigens, CD1 - analysis
Antigens, CD20 - analysis
CD3 Complex - analysis
CD4 Lymphocyte Count -
CD4-Positive T-Lymphocytes -
CD8-Positive T-Lymphocytes -
Dermoscopy -
Female -
Humans -
Immunohistochemistry -
Langerhans Cells - chemistry
Lymphocytes - chemistry
Male -
Melanoma - immunology
Melanoma - pathology
Microscopy, Confocal -
Middle Aged -
Nevus, Pigmented - immunology
Nevus, Pigmented - pathology
Skin Neoplasms - immunology
Skin Neoplasms - pathology
Young Adult -

Find related publications in this database (Keywords)
Dermoscopy
Melanocytic nevi
Melanoma
Meyerson's phenomenon
Reflectance confocal microscopy
Skin cancer
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