Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

Integrative Strukturelle Charakterisierung von Biopharmazeutika mittels Röntgenkleinwinkelstreuung (SAXS)

Projektleitung:

Madl Tobias

Laufzeit:

01.03.2018-31.07.2021

Programm:

FFG BRIDGE

Art der Forschung

Grundlagenforschung

Mitarbeiter*innen

Madl T., Projektleiter*in

Beteiligte MUG-Organisationseinheiten

Lehrstuhl für Molekularbiologie und Biochemie

Gefördert durch

Anton Paar GmbH, Anton-Paar-Straße 20, 8054 Graz, Österreich

Boehringer Ingelheim Austria GmbH, Dr. Boehringer-Gasse 5-11, 1121 Wien, Österreich

Österreichische Forschungsförderungsgesellschaft mbH (FFG) -Förderungen mit peer review , Sensengasse 1, 1090 Wien, Österreich

Publizierte Projektergebnisse

> Multiple regulatory intrinsically disordered motif... CELL REP. 2021; 36(4): 109446

> Imbalances in the eye lens proteome are linked to ... NAT STRUCT MOL BIOL. 2021; 28(2): 143-151.

> ATP regulates RNA-driven cold inducible RNA bindin... PROTEIN SCI. 2021; 30(7): 1438-1453.

> Guidelines for the use and interpretation of assay... AUTOPHAGY. 2021; 17(1): 1-382.

> Metabolic, Phenotypic, and Neuropathological Chara... J ALZHEIMERS DIS. 2021; 80(3): 1151-1168.

> Growing Human Hepatocellular Tumors Undergo a Glob... Cancers (Basel). 2021; 13(8):

> Lysophosphatidic Acid Induces Aerobic Glycolysis, ... Int J Mol Sci. 2021; 22(4):

> Tissue-Specific Landscape of Metabolic Dysregulati... Biomolecules. 2021; 11(2):

> Wide-Range, Rapid, and Specific Identification of ... ACS SENSORS. 2021; 6(8): 2911-2919.

> Metabolomics in der Transplantationsmedizin... Austrotransplant; OCT 20-22, 2021; Spielberg, AUSTRIA. 2021.

> Global analysis of protein arginine methylation... Protein Arginine Methylation: recent advances in basic and translational studies; MAY 11-12, 2021; Smithville, TX, USA. 2021.

> β-catenin regulates FOXP2 transcriptional activity... FEBS J. 2021; 288(10):3261-3284

> Dietary spermidine improves cognitive function.... Cell Rep. 2021; 35(2):108985-108985

> Structural and DNA-binding properties of the cytop... J Biol Chem. 2021; 297(4): 101167

> XIAP restrains TNF-driven intestinal inflammation ... Sci Immunol. 2021; 6(65): eabf7235

> Activation of efficient DNA repair mechanisms afte... Sci Rep. 2021; 11(1): 24116

> Integration of NMR, SAXS, and complementary techni... 17th EUROMAR; JUL 5-8, 2021; Portoroz, SLOVENIA. 2021.

> NMR-based metabolomics: what can it provide in pha... Lecture Series Pharma and Food; OCT 7, 2021; Vienna, AUSTRIA. 2021.

> Phosphorylation Regulates CIRBP Arginine Methylati... FRONT MOL BIOSCI. 2021; 8: 689687

> p53 Transactivation Domain Mediates Binding and Ph... Int J Mol Sci. 2021; 22(21):

> Intracellular drug binding affinities by NMR... ACTA CRYSTALLOGR D. 2021; 77: 1216-1217.

> Metabolic profiling links cardiovascular risk and ... ATHEROSCLEROSIS. 2021; 331: 45-53.

> Revealing the role of arginine methylation as key ... Emerging Topics in Biomolecular Magnetic Resonance; AUG 5, 2021; Göttingen, GERMANY. 2021.

> Reduced B12 uptake and increased gastrointestinal ... Microbiome. 2021; 9(1):193

> Branched-Chain Amino Acids Can Predict Mortality i... Nutrients. 2021; 13(9):

> Endothelial Lipase Modulates Paraoxonase 1 Content... Int J Mol Sci. 2021; 22(2):

> NLRP3 as a sensor of metabolism gone awry.... CURR OPIN BIOTECH. 2021; 68: 300-309.

> Nuclear Import Receptors Directly Bind to Arginine... Cell Rep. 2020; 33(12):108538-108538

> Metabolic reprogramming of donor T cells enhances ... Sci Transl Med. 2020; 12(567):

> Human Milk Oligosaccharides Modulate the Risk for ... mSystems. 2020; 5(3):

> Transgene integration causes RARB downregulation i... Sci Rep. 2020; 10(1): 6377-6377.

> Nonclassical nuclear localization signals mediate ... Proc Natl Acad Sci U S A. 2020; 117(15): 8503-8514.

> A small molecule chaperone rescues the stability a... FEBS Lett. 2020; 594(3):424-438

> Dipeptidyl peptidase 3 modulates the renin-angiote... J Biol Chem. 2020; 295(40):13711-13723

> Alternate Day Fasting Improves Physiological and M... Cell Metab. 2020; 31(4):878-881

> Probing Surfaces in Dynamic Protein Interactions.... J Mol Biol. 2020; 432(9):2949-2972

> RGG-mediated regulation of subcellular localizati... 12th NMR Winter Retreat of Protein-RNA Interactions; JAN 14-18, 2018; Parpan, SWITZERLAND. 2018.

> Calculating molecular structuresfrom NMR data.... NMR Summer School.; SEP 9-14, 2018; Niederöblarn, AUSTRIA. 2018.

> Structure determination of biomolecules using surf... XXVIII ICMRBS; AUG 19-24, 2018; Dublin, IRELAND. 2018.

> CRISPR-Cas9 – Ein Weg zum optimierten Menschen?... Science Lunch; OCT 18, 2018; Graz, AUSTRIA. 2018.

> Metabolomics - Hype oder Zukunftsmethode?... ; MAR 14, 2018; Munich, GERMANY. 2018.

> De novo structure prediction of biomolecules using... 26th Annual Meeting of the DGK ; MAR 5-8, 2018; Essen, GERMANY. 2018.

> Unravelling the role of FOXO proteins in ageing a... Central European Users´ Meeting 2018; SEP 5-6, 2018; Vienna, AUSTRIA . 2018.

> Bringing order to protein disorder: Deciphering th... Current Topics in Molecular Systems Biology; MAR 14-15, 2018; Munich, GERMANY. 2018.

> Unravelling the role of FOXO proteins in ageing a... The FEBS Congress 2018; Prague, CZECH REPUBLIC. 2018.