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Graier Wolfgang |

** = Publications listed in SCI/SSCI/Pubmed

2019

Full papers/articles (Journal)

** Burgstaller, S; Bischof, H; Gensch, T; Stryeck, S; Gottschalk, B; Ramadani-Muja, J; Eroglu, E; Rost, R; Balfanz, S; Baumann, A; Waldeck-Weiermair, M; Hay, JC; Madl, T; Graier, WF; Malli, R pH-Lemon, a Fluorescent Protein-Based pH Reporter for Acidic Compartments.
ACS Sens. 2019; 4(4): 883-891. [OPEN ACCESS]
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** Depaoli, MR; Hay, JC; Graier, WF; Malli, R The enigmatic ATP supply of the endoplasmic reticulum.
Biol Rev Camb Philos Soc. 2019; 94(2):610-628 [OPEN ACCESS]
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** Huber, K; Hofer, DC; Trefely, S; Pelzmann, HJ; Madreiter-Sokolowski, C; Duta-Mare, M; Schlager, S; Trausinger, G; Stryeck, S; Graier, WF; Kolb, D; Magnes, C; Snyder, NW; Prokesch, A; Kratky, D; Madl, T; Wellen, KE; Bogner-Strauss, JG N-acetylaspartate pathway is nutrient responsive and coordinates lipid and energy metabolism in brown adipocytes.
Biochim Biophys Acta Mol Cell Res. 2019; 1866(3): 337-348. [OPEN ACCESS]
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** Klec, C; Madreiter-Sokolowski, CT; Stryeck, S; Sachdev, V; Duta-Mare, M; Gottschalk, B; Depaoli, MR; Rost, R; Hay, J; Waldeck-Weiermair, M; Kratky, D; Madl, T; Malli, R; Graier, WF Glycogen Synthase Kinase 3 Beta Controls Presenilin-1-Mediated Endoplasmic Reticulum Ca²⁺ Leak Directed to Mitochondria in Pancreatic Islets and β-Cells.
Cell Physiol Biochem. 2019; 52(1): 57-75. [OPEN ACCESS]
PubMed PUBMED Central FullText FullText_MUG

 

** Madreiter-Sokolowski, CT; Waldeck-Weiermair, M; Bourguignon, MP; Villeneuve, N; Gottschalk, B; Klec, C; Stryeck, S; Radulovic, S; Parichatikanond, W; Frank, S; Madl, T; Malli, R; Graier, WF Enhanced inter-compartmental Ca2+ flux modulates mitochondrial metabolism and apoptotic threshold during aging.
Redox Biol. 2019; 20:458-466 [OPEN ACCESS]
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** Malli, R; Graier, WF IRE1α modulates ER and mitochondria crosstalk.
Nat Cell Biol. 2019; 21(6):667-668
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** Tiapko, O; Shrestha, N; Lindinger, S; de la Cruz, GG; Graziani, A; Klec, C; Butorac, C; Graier, WF; Kubista, H; Freichel, M; Birnbaumer, L; Romanin, C; Glasnov, T; Groschner, K Lipid-independent control of endothelial and neuronal TRPC3 channels by light
CHEM SCI. 2019; 10(9): 2837-2842.
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Reviews

** Bischof, H; Burgstaller, S; Waldeck-Weiermair, M; Rauter, T; Schinagl, M; Ramadani-Muja, J; Graier, WF; Malli, R Live-Cell Imaging of Physiologically Relevant Metal Ions Using Genetically Encoded FRET-Based Probes.
Cells. 2019; 8(5): [OPEN ACCESS]
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** Depaoli, MR; Bischof, H; Eroglu, E; Burgstaller, S; Ramadani-Muja, J; Rauter, T; Schinagl, M; Waldeck-Weiermair, M; Hay, JC; Graier, WF; Malli, R Live cell imaging of signaling and metabolic activities.
Pharmacol Ther. 2019; [OPEN ACCESS]
PubMed FullText FullText_MUG

 

Abstracts (Journal)

** Wallner, M; Eaton, D; Berretta, R; Bordag, N; Wu, JC; Jeong, M; Lin, Y; Borghetti, G; Zhao, HQ; Rainer, P; von Lewinski, D; Mohsin, S; Zugner, E; Blass, S; Graier, W; Zirlik, A; McKinsey, T; Wolfson, M; Houser, S HDAC inhibition improves myofibrillar relaxation and metabolism in a feline model of HFpEF
WIEN KLIN WOCHENSCHR. 2019; 131: 254-255.
Web of Science

 

2018

Full papers/articles (Journal)

** Alkan, HF; Walter, KE; Luengo, A; Madreiter-Sokolowski, CT; Stryeck, S; Lau, AN; Al-Zoughbi, W; Lewis, CA; Thomas, CJ; Hoefler, G; Graier, WF; Madl, T; Vander Heiden, MG; Bogner-Strauss, JG Cytosolic Aspartate Availability Determines Cell Survival When Glutamine Is Limiting.
Cell Metab. 2018; 28(5):706-720 [OPEN ACCESS]
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** Bernhart, E; Kogelnik, N; Prasch, J; Gottschalk, B; Goeritzer, M; Depaoli, MR; Reicher, H; Nusshold, C; Plastira, I; Hammer, A; Fauler, G; Malli, R; Graier, WF; Malle, E; Sattler, W 2-Chlorohexadecanoic acid induces ER stress and mitochondrial dysfunction in brain microvascular endothelial cells.
Redox Biol. 2018; 15:441-451 [OPEN ACCESS]
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** Deak, AT; Gottschalk, B; Eroglu, E; Rost, R; Waldeck-Weiermair, M; Graier, WF; Malli, R High-Resolution Imaging of STIM/Orai Subcellular Localization Using Array Confocal Laser Scanning Microscopy.
Methods Mol Biol. 2018; 1843(2):175-187
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** Depaoli, MR; Karsten, F; Madreiter-Sokolowski, CT; Klec, C; Gottschalk, B; Bischof, H; Eroglu, E; Waldeck-Weiermair, M; Simmen, T; Graier, WF; Malli, R Real-Time Imaging of Mitochondrial ATP Dynamics Reveals the Metabolic Setting of Single Cells.
Cell Rep. 2018; 25(2):501-512 [OPEN ACCESS]
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** Duta-Mare, M; Sachdev, V; Leopold, C; Kolb, D; Vujic, N; Korbelius, M; Hofer, DC; Xia, W; Huber, K; Auer, M; Gottschalk, B; Magnes, C; Graier, WF; Prokesch, A; Radovic, B; Bogner-Strauss, JG; Kratky, D Lysosomal acid lipase regulates fatty acid channeling in brown adipose tissue to maintain thermogenesis.
Biochim Biophys Acta. 2018; 1863(4):467-478 [OPEN ACCESS]
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** Eroglu, E; Bischof, H; Charoensin, S; Waldeck-Weiermaier, M; Graier, WF; Malli, R Real-Time Imaging of Nitric Oxide Signals in Individual Cells Using geNOps.
Methods Mol Biol. 2018; 1747: 23-34.
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** Gottschalk, B; Klec, C; Waldeck-Weiermair, M; Malli, R; Graier, WF Intracellular Ca2+ release decelerates mitochondrial cristae dynamics within the junctions to the endoplasmic reticulum.
Pflugers Arch. 2018; 470(8):1193-1203 [OPEN ACCESS]
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** Jain, M; Mann, TD; Stulić, M; Rao, SP; Kirsch, A; Pullirsch, D; Strobl, X; Rath, C; Reissig, L; Moreth, K; Klein-Rodewald, T; Bekeredjian, R; Gailus-Durner, V; Fuchs, H; Hrabě de Angelis, M; Pablik, E; Cimatti, L; Martin, D; Zinnanti, J; Graier, WF; Sibilia, M; Frank, S; Levanon, EY; Jantsch, MF RNA editing of Filamin A pre-mRNA regulates vascular contraction and diastolic blood pressure.
EMBO J. 2018; [OPEN ACCESS]
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** Opelt, M; Wölkart, G; Eroglu, E; Waldeck-Weiermair, M; Malli, R; Graier, WF; Kollau, A; Fassett, JT; Schrammel, A; Mayer, B; Gorren, ACF Sustained Formation of Nitroglycerin-Derived Nitric Oxide by Aldehyde Dehydrogenase-2 in Vascular Smooth Muscle without Added Reductants: Implications for the Development of Nitrate Tolerance.
Mol Pharmacol. 2018; 93(4):335-343 [OPEN ACCESS]
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** Rockenfeller, P; Smolnig, M; Diessl, J; Bashir, M; Schmiedhofer, V; Knittelfelder, O; Ring, J; Franz, J; Foessl, I; Khan, MJ; Rost, R; Graier, WF; Kroemer, G; Zimmermann, A; Carmona-Gutierrez, D; Eisenberg, T; Büttner, S; Sigrist, SJ; Kühnlein, RP; Kohlwein, SD; Gourlay, CW; Madeo, F Diacylglycerol triggers Rim101 pathway-dependent necrosis in yeast: a model for lipotoxicity.
Cell Death Differ. 2018; 25(4):765-781 [OPEN ACCESS]
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** Yiallouris, A; Patrikios, I; Johnson, EO; Sereti, E; Dimas, K; De Ford, C; Fedosova, NU; Graier, WF; Sokratous, K; Kyriakou, K; Stephanou, A Annonacin promotes selective cancer cell death via NKA-dependent and SERCA-dependent pathways.
Cell Death Dis. 2018; 9(7): 764-764. [OPEN ACCESS]
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Reviews

** Eroglu, E; Charoensin, S; Bischof, H; Ramadani, J; Gottschalk, B; Depaoli, MR; Waldeck-Weiermair, M; Graier, WF; Malli, R Genetic biosensors for imaging nitric oxide in single cells.
Free Radic Biol Med. 2018; [OPEN ACCESS]
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** Madreiter-Sokolowski, CT; Sokolowski, AA; Waldeck-Weiermair, M; Malli, R; Graier, WF Targeting Mitochondria to Counteract Age-Related Cellular Dysfunction.
Genes (Basel). 2018; 9(3): [OPEN ACCESS]
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Abstracts (Journal)

** Deak, A; Gottschalk, B; Ketszeri, M; Rost, R; Malli, R; Graier, W; Bork, T; Huber, T; Eller, K; Rosenkranz, A IMPAIRED MITOCHONDRIALCALCIUM UPTAKE AND DAMAGED MITOCHONDRIAL STRUCTURE IN PODOCYTES EXPOSED TO HIGH-GLUCOSE
NEPHROL DIAL TRANSPL. 2018; 33: -55th ERA-EDTA Congress; MAY 24-27, 2018; Copenhagen, DENMARK. [Poster]
Web of Science

 

2017

Full papers/articles (Journal)

** Baker, D; Pryce, G; Visintin, C; Sisay, S; Bondarenko, AI; Vanessa Ho, WS; Jackson, SJ; Williams, TE; Al-Izki, S; Sevastou, I; Okuyama, M; Graier, WF; Stevenson, LA; Tanner, C; Ross, R; Pertwee, RG; Henstridge, CM; Irving, AJ; Schulman, J; Powell, K; Baker, MD; Giovannoni, G; Selwood, DL Big conductance calcium-activated potassium channel openers control spasticity without sedation.
Br J Pharmacol. 2017; 174(16):2662-2681 [OPEN ACCESS]
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** Bärnthaler, T; Maric, J; Platzer, W; Konya, V; Theiler, A; Hasenöhrl, C; Gottschalk, B; Trautmann, S; Schreiber, Y; Graier, WF; Schicho, R; Marsche, G; Olschewski, A; Thomas, D; Schuligoi, R; Heinemann, A The Role of PGE2 in Alveolar Epithelial and Lung Microvascular Endothelial Crosstalk.
Sci Rep. 2017; 7(1): 7923-7923. [OPEN ACCESS]
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** Bischof, H; Rehberg, M; Stryeck, S; Artinger, K; Eroglu, E; Waldeck-Weiermair, M; Gottschalk, B; Rost, R; Deak, AT; Niedrist, T; Vujic, N; Lindermuth, H; Prassl, R; Pelzmann, B; Groschner, K; Kratky, D; Eller, K; Rosenkranz, AR; Madl, T; Plesnila, N; Graier, WF; Malli, R Novel genetically encoded fluorescent probes enable real-time detection of potassium in vitro and in vivo.
Nat Commun. 2017; 8(1):1422-1422 [OPEN ACCESS]
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** Charoensin, S; Eroglu, E; Opelt, M; Bischof, H; Madreiter-Sokolowski, CT; Kirsch, A; Depaoli, MR; Frank, S; Schrammel, A; Mayer, B; Waldeck-Weiermair, M; Graier, WF; Malli, R Intact mitochondrial Ca2+ uniport is essential for agonist-induced activation of endothelial nitric oxide synthase (eNOS).
Free Radic Biol Med. 2017; 102(1):248-259 [OPEN ACCESS]
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** Eroglu, E; Hallström, S; Bischof, H; Opelt, M; Schmidt, K; Mayer, B; Waldeck-Weiermair, M; Graier, WF; Malli, R Real-time visualization of distinct nitric oxide generation of nitric oxide synthase isoforms in single cells.
Nitric Oxide. 2017; 70(31):59-67 [OPEN ACCESS]
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** Eroglu, E; Rost, R; Bischof, H; Blass, S; Schreilechner, A; Gottschalk, B; Depaoli, MR; Klec, C; Charoensin, S; Madreiter-Sokolowski, CT; Ramadani, J; Waldeck-Weiermair, M; Graier, WF; Malli, R Application of Genetically Encoded Fluorescent Nitric Oxide (NO•) Probes, the geNOps, for Real-time Imaging of NO• Signals in Single Cells.
J Vis Exp. 2017; 5(121): [OPEN ACCESS]
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** Hofer, DC; Pessentheiner, AR; Pelzmann, HJ; Schlager, S; Madreiter-Sokolowski, CT; Kolb, D; Eichmann, TO; Rechberger, G; Bilban, M; Graier, WF; Kratky, D; Bogner-Strauss, JG Critical role of the peroxisomal protein PEX16 in white adipocyte development and lipid homeostasis.
Biochim Biophys Acta Mol Cell Biol Lipids. 2017; 1862(3):358-368 [OPEN ACCESS]
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** Madreiter-Sokolowski, CT; Győrffy, B; Klec, C; Sokolowski, AA; Rost, R; Waldeck-Weiermair, M; Malli, R; Graier, WF UCP2 and PRMT1 are key prognostic markers for lung carcinoma patients.
Oncotarget. 2017; 8(46):80278-80285 [OPEN ACCESS]
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** Plastira, I; Bernhart, E; Goeritzer, M; DeVaney, T; Reicher, H; Hammer, A; Lohberger, B; Wintersperger, A; Zucol, B; Graier, WF; Kratky, D; Malle, E; Sattler, W Lysophosphatidic acid via LPA-receptor 5/protein kinase D-dependent pathways induces a motile and pro-inflammatory microglial phenotype.
J Neuroinflammation. 2017; 14(1):253-253 [OPEN ACCESS]
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Reviews

** Madreiter-Sokolowski, CT; Sokolowski, AA; Graier, WF Dosis Facit Sanitatem-Concentration-Dependent Effects of Resveratrol on Mitochondria.
Nutrients. 2017; 9(10): [OPEN ACCESS]
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** Malli, R; Graier, WF The Role of Mitochondria in the Activation/Maintenance of SOCE: The Contribution of Mitochondrial Ca2+ Uptake, Mitochondrial Motility, and Location to Store-Operated Ca2+ Entry.
Adv Exp Med Biol. 2017; 993(14-15):297-319
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Editorials

** Graier, WF; Malli, R Mitochondrial calcium: a crucial hub for cancer cell metabolism?
TRANSL CANCER RES. 2017; 6: S124-S127.
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** Groschner, K; Graier, WF; Romanin, C Store-Operated Ca2+ Entry (SOCE) Pathways Emerging Signaling Concepts in Human (Patho)physiology Second Edition Preface
ADV EXP MED BIOL. 2017; 993: V-V.
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Abstracts (Journal)

** Plastira, J; Bernhart, E; Zucol, B; Graier, W; Sattler, W Lysophosphatidic acid (LPA) controls the migratory and inflammatory response of microglia via the LPAR5-PKDs axis
GLIA. 2017; 65: E480-E480.-13th European Meeting on Glial Cells in Health and Disease; JUL 08-11, 2017; Edinburgh, SCOTLAND. [Poster]
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2016

Full papers/articles (Journal)

** Eroglu, E; Gottschalk, B; Charoensin, S; Blass, S; Bischof, H; Rost, R; Madreiter-Sokolowski, CT; Pelzmann, B; Bernhart, E; Sattler, W; Hallström, S; Malinski, T; Waldeck-Weiermair, M; Graier, WF; Malli, R Development of novel FP-based probes for live-cell imaging of nitric oxide dynamics.
Nat Commun. 2016; 7(3):10623-10623 [OPEN ACCESS]
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** Madreiter-Sokolowski, CT; Gottschalk, B; Parichatikanond, W; Eroglu, E; Klec, C; Waldeck-Weiermair, M; Malli, R; Graier, WF Resveratrol Specifically Kills Cancer Cells by a Devastating Increase in the Ca2+ Coupling Between the Greatly Tethered Endoplasmic Reticulum and Mitochondria.
Cell Physiol Biochem. 2016; 39(4):1404-1420 [OPEN ACCESS]
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** Madreiter-Sokolowski, CT; Klec, C; Parichatikanond, W; Stryeck, S; Gottschalk, B; Pulido, S; Rost, R; Eroglu, E; Hofmann, NA; Bondarenko, AI; Madl, T; Waldeck-Weiermair, M; Malli, R; Graier, WF PRMT1-mediated methylation of MICU1 determines the UCP2/3 dependency of mitochondrial Ca(2+) uptake in immortalized cells.
Nat Commun. 2016; 7(4):12897-12897 [OPEN ACCESS]
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** Malli, R; Eroglu, E; Waldeck-Weiermair, M; Graier, WF Filling a GAP-An Optimized Probe for ER Ca(2+) Imaging In Vivo.
Cell Chem Biol. 2016; 23(6):641-643 [OPEN ACCESS]
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** Opelt, M; Eroglu, E; Waldeck-Weiermair, M; Russwurm, M; Koesling, D; Malli, R; Graier, WF; Fassett, JT; Schrammel, A; Mayer, B Formation of Nitric Oxide by Aldehyde Dehydrogenase-2 Is Necessary and Sufficient for Vascular Bioactivation of Nitroglycerin.
J Biol Chem. 2016; 291(46):24076-24084 [OPEN ACCESS]
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** Prokesch, A; Pelzmann, HJ; Pessentheiner, AR; Huber, K; Madreiter-Sokolowski, CT; Drougard, A; Schittmayer, M; Kolb, D; Magnes, C; Trausinger, G; Graier, WF; Birner-Gruenberger, R; Pospisilik, JA; Bogner-Strauss, JG N-acetylaspartate catabolism determines cytosolic acetyl-CoA levels and histone acetylation in brown adipocytes.
Sci Rep. 2016; 6(5):23723-23723 [OPEN ACCESS]
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** Radović, B; Vujić, N; Leopold, C; Schlager, S; Goeritzer, M; Patankar, JV; Korbelius, M; Kolb, D; Reindl, J; Wegscheider, M; Tomin, T; Birner-Gruenberger, R; Schittmayer, M; Groschner, L; Magnes, C; Diwoky, C; Frank, S; Steyrer, E; Du, H; Graier, WF; Madl, T; Kratky, D Lysosomal acid lipase regulates VLDL synthesis and insulin sensitivity in mice.
Diabetologia. 2016; 59(8):1743-1752 [OPEN ACCESS]
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** Vinod, M; Patankar, JV; Sachdev, V; Frank, S; Graier, WF; Kratky, D; Kostner, GM MiR-206 is expressed in pancreatic islets and regulates glucokinase activity.
Am J Physiol Endocrinol Metab. 2016; 311(1):E175-E185 [OPEN ACCESS]
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** Vujic, N; Schlager, S; Eichmann, TO; Madreiter-Sokolowski, CT; Goeritzer, M; Rainer, S; Schauer, S; Rosenberger, A; Woelfler, A; Doddapattar, P; Zimmermann, R; Hoefler, G; Lass, A; Graier, WF; Radovic, B; Kratky, D Monoglyceride lipase deficiency modulates endocannabinoid signaling and improves plaque stability in ApoE-knockout mice.
Atherosclerosis. 2016; 244(3):9-21 [OPEN ACCESS]
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Abstracts (Journal)

** Baker, D; Pryce, G; Visintin, C; Bondarenko, AI; Ho, WSV; Williams, TE; Sevastou, I; Graier, WF; Baker, MD; Giovannoni, G; Selwood, DL Big conductance calcium-activated potassium channel activation is a novel way to control spasticity without sedation
MULT SCLER J. 2016; 22: 380-381.-32nd Congress of the European-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis (ECTRIMS); SEP 14-17, 2016; London, ENGLAND. [Poster]
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** Eroglu, E; Waldeck-Weiermair, M; Graier, WF; Malli, R Development of novel fluorescent protein-based probes for live-cell imaging of nitric oxide dynamics
FREE RADICAL BIO MED. 2016; 96: S18-S18.-Conference of the Society-for-Free-Radical-Research-Europe (SFRR-E); JUN 08-11, 2016; Budapest, HUNGARY. [Oral Communication]
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** Malli, R; Eroglu, E; Waldeck-Weiermair, M; Graier, WF Ca2+-triggered nitric oxide production in endothelial cells is under the control of mitochondrial Ca2+ uptake
FREE RADICAL BIO MED. 2016; 96: S25-S25.-Conference of the Society-for-Free-Radical-Research-Europe (SFRR-E); JUN 08-11, 2016; Budapest, HUNGARY. [Oral Communication]
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** Malli, R; Eroglu, E; Waldeck-Weiermair, M; Graier, WF Ca2+-Triggered Nitric Oxide Production in Endothelial Cells is Under the Control of Mitochondrial Ca2+Uptake
J VASC RES. 2016; 53: 24-24.-12th International Symposium on Mechanisms of Vasodilatation; NOV 06-09, 2016; Rochester, NY. [Poster]
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** Vujic, N; Schlager, S; Eichmann, TO; Goeritzer, M; Madreiter-Sokolowski, CT; Schauer, S; Lass, A; Zimmermann, R; Hoefler, G; Graier, WF; Radovic, B; Kratky, D MONOGLYCERIDE LIPASE REGULATES ENDOCANNABINOID TONE AND ATHEROSCLEROTIC PLAQUE STRUCTURE IN APOLIPOPROTEIN E-DEFICIENT MICE
ATHEROSCLEROSIS. 2016; 252: E259-E259.-Congress of the European-Atherosclerosis-Society (EAS); MAY 29-JUN 01, 2016; Innsbruck, AUSTRIA. [Oral Communication]
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2015

Full papers/articles (Journal)

** Bondarenko, AI; Parichatikanond, W; Madreiter, CT; Rost, R; Waldeck-Weiermair, M; Malli, R; Graier, WF UCP2 modulates single-channel properties of a MCU-dependent Ca(2+) inward current in mitochondria.
Pflugers Arch. 2015; 467(12):2509-2518 [OPEN ACCESS]
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** Deak, AT; Jean-Quartier, C; Bondarenko, AI; Groschner, LN; Malli, R; Graier, WF; Waldeck-Weiermair, M Assessment of mitochondrial Ca²⁺ uptake.
Methods Mol Biol. 2015; 1264(12):421-439
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** Goeritzer, M; Vujic, N; Schlager, S; Chandak, PG; Korbelius, M; Gottschalk, B; Leopold, C; Obrowsky, S; Rainer, S; Doddapattar, P; Aflaki, E; Wegscheider, M; Sachdev, V; Graier, WF; Kolb, D; Radovic, B; Kratky, D Active autophagy but not lipophagy in macrophages with defective lipolysis.
Biochim Biophys Acta. 2015; 1851(10):1304-1316 [OPEN ACCESS]
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** Hofmann, NA; Yang, J; Trauger, SA; Nakayama, H; Huang, L; Strunk, D; Moses, MA; Klagsbrun, M; Bischoff, J; Graier, WF The GPR 55 agonist, L-α-lysophosphatidylinositol, mediates ovarian carcinoma cell-induced angiogenesis.
Br J Pharmacol. 2015; 172(16):4107-4118 [OPEN ACCESS]
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** Waldeck-Weiermair, M; Bischof, H; Blass, S; Deak, AT; Klec, C; Graier, T; Roller, C; Rost, R; Eroglu, E; Gottschalk, B; Hofmann, NA; Graier, WF; Malli, R Generation of Red-Shifted Cameleons for Imaging Ca²⁺ Dynamics of the Endoplasmic Reticulum.
Sensors (Basel). 2015; 15(6):13052-13068 [OPEN ACCESS]
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** Waldeck-Weiermair, M; Malli, R; Parichatikanond, W; Gottschalk, B; Madreiter-Sokolowski, CT; Klec, C; Rost, R; Graier, WF Rearrangement of MICU1 multimers for activation of MCU is solely controlled by cytosolic Ca(2.).
Sci Rep. 2015; 5(50):15602-15602 [OPEN ACCESS]
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Abstracts (Journal)

** Vinod, M; Patankar, JV; Sachdev, V; Al-Zoughbi, WAEL; Hofler, G; Frank, SASA; Graier, WF; Kratky, D; Kostner, GM MICRO-RNA 206 AFFECTS GLUCOSE INDUCED INSULIN SECRETION UNDER HIGH-FAT DIET
ATHEROSCLEROSIS. 2015; 241(1):E83-E83.-83rd Congress of the European-Atherosclerosis-Society (EAS); MAR 22-25, 2015; Glasgow, SCOTLAND. [Poster]
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2014

Full papers/articles (Journal)

** Bondarenko, AI; Jean-Quartier, C; Parichatikanond, W; Alam, MR; Waldeck-Weiermair, M; Malli, R; Graier, WF Mitochondrial Ca(2+) uniporter (MCU)-dependent and MCU-independent Ca(2+) channels coexist in the inner mitochondrial membrane.
Pflugers Arch. 2014; 466(7):1411-1420 [OPEN ACCESS]
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** Deak, AT; Blass, S; Khan, MJ; Groschner, LN; Waldeck-Weiermair, M; Hallström, S; Graier, WF; Malli, R IP3-mediated STIM1 oligomerization requires intact mitochondrial Ca2+ uptake.
J Cell Sci. 2014; 127(Pt 13):2944-2955 [OPEN ACCESS]
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** Goeritzer, M; Schlager, S; Radovic, B; Madreiter, CT; Rainer, S; Thomas, G; Lord, CC; Sacks, J; Brown, AL; Vujic, N; Obrowsky, S; Sachdev, V; Kolb, D; Chandak, PG; Graier, WF; Sattler, W; Brown, JM; Kratky, D Deletion of CGI-58 or adipose triglyceride lipase differently affects macrophage function and atherosclerosis.
J Lipid Res. 2014; 55(12):2562-2575 [OPEN ACCESS]
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** Hofmann, NA; Barth, S; Waldeck-Weiermair, M; Klec, C; Strunk, D; Malli, R; Graier, WF TRPV1 mediates cellular uptake of anandamide and thus promotes endothelial cell proliferation and network-formation.
Biol Open. 2014; 3(12):1164-1172 [OPEN ACCESS]
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** Kennedy, BE; Madreiter, CT; Vishnu, N; Malli, R; Graier, WF; Karten, B Adaptations of energy metabolism associated with increased levels of mitochondrial cholesterol in Niemann-Pick type C1-deficient cells.
J Biol Chem. 2014; 289(23):16278-16289 [OPEN ACCESS]
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** Kozina, A; Opresnik, S; Wong, MS; Hallström, S; Graier, WF; Malli, R; Schröder, K; Schmidt, K; Frank, S Oleoyl-lysophosphatidylcholine limits endothelial nitric oxide bioavailability by induction of reactive oxygen species.
PLoS One. 2014; 9(11):e113443-e113443 [OPEN ACCESS]
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** Rossmann, C; Windpassinger, C; Brunner, D; Kovacevic, A; Schweighofer, N; Malli, R; Schuligoi, R; Prokesch, A; Kluve-Beckerman, B; Graier, WF; Kratky, D; Sattler, W; Malle, E Characterization of rat serum amyloid A4 (SAA4): a novel member of the SAA superfamily.
Biochem Biophys Res Commun. 2014; 450(4):1643-1649 [OPEN ACCESS]
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** Vinod, M; Chennamsetty, I; Colin, S; Belloy, L; De Paoli, F; Schaider, H; Graier, WF; Frank, S; Kratky, D; Staels, B; Chinetti-Gbaguidi, G; Kostner, GM miR-206 controls LXRα expression and promotes LXR-mediated cholesterol efflux in macrophages.
Biochim Biophys Acta. 2014; 1841(6):827-835 [OPEN ACCESS]
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** Vishnu, N; Jadoon Khan, M; Karsten, F; Groschner, LN; Waldeck-Weiermair, M; Rost, R; Hallström, S; Imamura, H; Graier, WF; Malli, R ATP increases within the lumen of the endoplasmic reticulum upon intracellular Ca2+ release.
Mol Biol Cell. 2014; 25(3):368-379 [OPEN ACCESS]
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Reviews

** Groschner, LN; Alam, MR; Graier, WF Metabolism-secretion coupling and mitochondrial calcium activities in clonal pancreatic β-cells.
Vitam Horm. 2014; 95(3):63-86
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Abstracts (Journal)

** Kozina, A; Opresnik, S; Hallstrom, S; Schmidt, K; Malli, R; Graier, WF; Frank, S ACYL CHAIN-DEPENDENT EFFECT OF LYSOPHOSPHATIDYLCHOLINE ON ENDOTHELIAL NITRIC OXIDE SYNTHASE AND NO BIOAVAILABILITY IN ENDOTHELIAL CELLS
ATHEROSCLEROSIS. 2014; 235(2): E120-E120. [Poster]
Web of Science

 

** Vinod, M; Chennamsetty, I; Colin, S; Belloy, L; De Paoli, F; Schaider, H; Graier, W; Frank, S; Kratky, D; Staels, B; Chinetti-Gbaguidi, G; Kostner, G MIR-206 CONTROLS LXR-ALPHA EXPRESSION AND PROMOTES LXR-MEDIATED CHOLESTEROL EFFLUX IN MACROPHAGES
ATHEROSCLEROSIS. 2014; 235(2):E39-E39.-82nd Congress of the European-Atherosclerosis-Society (EAS); MAY 31-JUN 03, 2014; Madrid, SPAIN. [Poster]
Web of Science

 

2013

Full papers/articles (Journal)

** Bondarenko, AI; Drachuk, K; Panasiuk, O; Sagach, V; Deak, AT; Malli, R; Graier, WF N-Arachidonoyl glycine suppresses Na⁺/Ca²⁺ exchanger-mediated Ca²⁺ entry into endothelial cells and activates BK(Ca) channels independently of GPCRs.
Br J Pharmacol. 2013; 169(4):933-948 [OPEN ACCESS]
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** Bondarenko, AI; Jean-Quartier, C; Malli, R; Graier, WF Characterization of distinct single-channel properties of Ca²⁺ inward currents in mitochondria.
Pflugers Arch. 2013; 465(7):997-1010 [OPEN ACCESS]
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** Deak, AT; Groschner, LN; Alam, MR; Seles, E; Bondarenko, AI; Graier, WF; Malli, R The endocannabinoid N-arachidonoyl glycine (NAGly) inhibits store-operated Ca2+ entry by preventing STIM1-Orai1 interaction.
J Cell Sci. 2013; 126(Pt 4):879-888 [OPEN ACCESS]
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** Pessentheiner, AR; Pelzmann, HJ; Walenta, E; Schweiger, M; Groschner, LN; Graier, WF; Kolb, D; Uno, K; Miyazaki, T; Nitta, A; Rieder, D; Prokesch, A; Bogner-Strauss, JG NAT8L (N-acetyltransferase 8-like) accelerates lipid turnover and increases energy expenditure in brown adipocytes.
J Biol Chem. 2013; 288(50):36040-36051 [OPEN ACCESS]
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** Rao, SP; Riederer, M; Lechleitner, M; Hermansson, M; Desoye, G; Hallström, S; Graier, WF; Frank, S Acyl chain-dependent effect of lysophosphatidylcholine on endothelium-dependent vasorelaxation.
PLoS One. 2013; 8(5):e65155-e65155 [OPEN ACCESS]
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** Schernthaner, M; Leitinger, G; Wolinski, H; Kohlwein, SD; Reisinger, B; Barb, RA; Graier, WF; Heitz, J; Groschner, K; Enhanced Ca2+ Entry and Tyrosine Phosphorylation Mediate Nanostructure-Induced Endothelial Proliferation.
J NANOMATER. 2013; 251063 [OPEN ACCESS]
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** Waldeck-Weiermair, M; Deak, AT; Groschner, LN; Alam, MR; Jean-Quartier, C; Malli, R; Graier, WF Molecularly distinct routes of mitochondrial Ca2+ uptake are activated depending on the activity of the sarco/endoplasmic reticulum Ca2+ ATPase (SERCA).
J Biol Chem. 2013; 288(21):15367-15379 [OPEN ACCESS]
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2012

Full papers/articles (Journal)

** Aflaki, E; Doddapattar, P; Radovic, B; Povoden, S; Kolb, D; Vujic, N; Wegscheider, M; Koefeler, H; Hornemann, T; Graier, WF; Malli, R; Madeo, F; Kratky, D C16 ceramide is crucial for triacylglycerol-induced apoptosis in macrophages.
Cell Death Dis. 2012; 3(6):e280-e280 [OPEN ACCESS]
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** Alam, MR; Groschner, LN; Parichatikanond, W; Kuo, L; Bondarenko, AI; Rost, R; Waldeck-Weiermair, M; Malli, R; Graier, WF Mitochondrial Ca2+ uptake 1 (MICU1) and mitochondrial ca2+ uniporter (MCU) contribute to metabolism-secretion coupling in clonal pancreatic β-cells.
J Biol Chem. 2012; 287(41):34445-34454 [OPEN ACCESS]
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** Brkić, L; Riederer, M; Graier, WF; Malli, R; Frank, S Acyl chain-dependent effect of lysophosphatidylcholine on cyclooxygenase (COX)-2 expression in endothelial cells.
Atherosclerosis. 2012; 224(2):348-354 [OPEN ACCESS]
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** Crnkovic, S; Riederer, M; Lechleitner, M; Hallström, S; Malli, R; Graier, WF; Lindenmann, J; Popper, H; Olschewski, H; Olschewski, A; Frank, S Docosahexaenoic acid-induced unfolded protein response, cell cycle arrest, and apoptosis in vascular smooth muscle cells are triggered by Ca²⁺-dependent induction of oxidative stress.
Free Radic Biol Med. 2012; 52(9):1786-1795 [OPEN ACCESS]
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** Jean-Quartier, C; Bondarenko, AI; Alam, MR; Trenker, M; Waldeck-Weiermair, M; Malli, R; Graier, WF Studying mitochondrial Ca(2+) uptake - a revisit.
Mol Cell Endocrinol. 2012; 353(1-2):114-127 [OPEN ACCESS]
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** Khan, MJ; Alam, MR; Waldeck-Weiermair, M; Karsten, F; Groschner, L; Riederer, M; Hallstroem, S; Rockenfeller, P; Konya, V; Heinemann, A; Madeo, F; Graier, WF; Malli, R Inhibition of autophagy rescues palmitic acid induced necroptosis of endothelial cells.
J Biol Chem. 2012; 287(25):21110-21120 [OPEN ACCESS]
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** Waldeck-Weiermair, M; Alam, MR; Khan, MJ; Deak, AT; Vishnu, N; Karsten, F; Imamura, H; Graier, WF; Malli, R Spatiotemporal Correlations between Cytosolic and Mitochondrial Ca(2+) Signals Using a Novel Red-Shifted Mitochondrial Targeted Cameleon.
PLoS One. 2012; 7(9):e45917-e45917 [OPEN ACCESS]
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** Willer, EA; Malli, R; Bondarenko, AI; Zahler, S; Vollmar, AM; Graier, WF; Fürst, R The vascular barrier-protecting hawthorn extract WS® 1442 raises endothelial calcium levels by inhibition of SERCA and activation of the IP3 pathway.
J Mol Cell Cardiol. 2012; 53(4):567-577
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Reviews

** Groschner, LN; Waldeck-Weiermair, M; Malli, R; Graier, WF Endothelial mitochondria--less respiration, more integration.
Pflugers Arch. 2012; 464(1):63-76 [OPEN ACCESS]
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2011

Full papers/articles (Journal)

** Aflaki, E; Radovic, B; Chandak, PG; Kolb, D; Eisenberg, T; Ring, J; Fertschai, I; Uellen, A; Wolinski, H; Kohlwein, SD; Zechner, R; Levak-Frank, S; Sattler, W; Graier, WF; Malli, R; Madeo, F; Kratky, D Triacylglycerol accumulation activates the mitochondrial apoptosis pathway in macrophages.
J Biol Chem. 2011; 286(9): 7418-7428. [OPEN ACCESS]
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** Bondarenko, AI; Malli, R; Graier, WF The GPR55 agonist lysophosphatidylinositol directly activates intermediate-conductance Ca2+ -activated K+ channels.
Pflugers Arch. 2011; 462(2):245-255 [OPEN ACCESS]
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** Bondarenko, AI; Malli, R; Graier, WF The GPR55 agonist lysophosphatidylinositol acts as an intracellular messenger and bidirectionally modulates Ca2+ -activated large-conductance K+ channels in endothelial cells.
Pflugers Arch. 2011; 461(1):177-189 [OPEN ACCESS]
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** Waldeck-Weiermair, M; Jean-Quartier, C; Rost, R; Khan, MJ; Vishnu, N; Bondarenko, AI; Imamura, H; Malli, R; Graier, WF Leucine Zipper EF Hand-containing Transmembrane Protein 1 (Letm1) and Uncoupling Proteins 2 and 3 (UCP2/3) Contribute to Two Distinct Mitochondrial Ca2+ Uptake Pathways.
J Biol Chem. 2011; 286(32):28444-28455 [OPEN ACCESS]
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Corrections

** Riederer, M; Ojala, PJ; Hrzenjak, A; Graier, WF; Malli, R; Tritscher, M; Hermansson, M; Watzer, B; Schweer, H; Desoye, G; Heinemann, A; Frank, S Acyl chain-dependent effect of lysophosphatidylcholine on endothelial prostacyclin production (vol 51, pg 2957, 2010)
J LIPID RES. 2011; 52(1): 185-185.
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Abstracts (Journal)

** Brkic, L; Riederer, M; Malli, R; Graier, W; Frank, S ACYL CHAIN-DEPENDENT EFFECT OF LYSOPHOSPHATIDYLCHOLINES ON COX-2 EXPRESSION IN VASCULAR ENDOTHELIAL CELLS
ATHEROSCLEROSIS SUPP. 2011; 12(1):10-10.-79th Congress of the European-Atherosclerosis-Society (EAS); JUN 26-29, 2011; Gothenburg, SWEDEN. [Oral Communication]
Web of Science

 

** Duvigneau, J; Muellebner, A; Paier-Pourani, J; Pagavathiethu, J; Kehrer, I; Malli, R; Graier, W; Redl, H; Kozlov, AV INFLAMMATORY MEDIATORS CAUSE HEPATOCYTE DYSFUNCTION VIA ENDOPLASMIC RETICULUM FAILURE
SHOCK. 2011; 36: 15-15.-Shock; [Poster]
Web of Science

 

** Paier-Pourani, J; Kehrer, I; Malli, R; Kozlov, AV; Graier, W; Redl, H THE IMPACT OF MITOCHONDRIAL ROS ON CELLULAR DYSFUNCTION INDUCED BY INFLAMMATORY MEDIATORS
SHOCK. 2011; 36: 27-27. [Poster]
Web of Science

 

** Willer, E; Malli, R; Zahler, S; Vollmar, AM; Graier, W; Frust, R Insights into the Ca2+-regulating molecular mechanisms of the hawthorn extract WS (R) 1442 in endothelial cells
NAUNYN-SCHMIED ARCH PHARMACOL. 2011; 383: 42-43. [Poster]
Web of Science

 

** Willer, E; Malli, R; Zahler, S; Vollmar, AM; Graier, W; Furst, R Mechanistic insights into the rise of cytosolic Ca(2+) levels during endothelial barrier protection induced by the hawthorn extract WS (R) 1442
J VASC RES. 2011; 48: 241-241.-Joint Meeting of the European-Society-for-Microcirculation (ESM)/Society-of-Microcirculation-and-Vascular-Biology (GfMVB); OCT 13-16, 2011; Munich, GERMANY. [Oral Communication]
Web of Science

 

2010

Full papers/articles (Journal)

** Bentley, M; Nycz, DC; Joglekar, A; Fertschai, I; Malli, R; Graier, WF; Hay, JC Vesicular calcium regulates coat retention, fusogenicity, and size of pre-Golgi intermediates.
Mol Biol Cell. 2010; 21(6):1033-1046 [OPEN ACCESS]
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** Bernhart, E; Kollroser, M; Rechberger, G; Reicher, H; Heinemann, A; Schratl, P; Hallström, S; Wintersperger, A; Nusshold, C; Devaney, T; Zorn-Pauly, K; Malli, R; Graier, W; Malle, E; Sattler, W Lysophosphatidic acid receptor activation affects the C13NJ microglia cell line proteome leading to alterations in glycolysis, motility, and cytoskeletal architecture.
Proteomics. 2010; 10(1): 141-158. [OPEN ACCESS]
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** Bondarenko, A; Waldeck-Weiermair, M; Naghdi, S; Poteser, M; Malli, R; Graier, WF GPR55-dependent and -independent ion signalling in response to lysophosphatidylinositol in endothelial cells.
Br J Pharmacol. 2010; 161(2): 308-320. [OPEN ACCESS]
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** Malli, R; Graier, WF Mitochondrial Ca2+ channels: Great unknowns with important functions.
FEBS Lett. 2010; 584(10): 1942-1947. [OPEN ACCESS]
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** Naghdi, S; Waideck-Weiermair, M; Fertschai, I; Poteser, M; Graier, WF; Malli, R Mitochondrial Ca2+ uptake and not mitochondrial motility is required for STIM1-Orai1-dependent store-operated Ca2+ entry.
J CELL SCI. 2010; 123(Pt 15): 2553-2564. [OPEN ACCESS]
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** Riederer, M; Ojala, PJ; Hrzenjak, A; Graier, WF; Malli, R; Tritscher, M; Hermansson, M; Watzer, B; Schweer, H; Desoye, G; Heinemann, A; Frank, S Acyl chain-dependent effect of lysophosphatidylcholine on endothelial prostacyclin production.
J Lipid Res. 2010; 51(10):2957-2966 [OPEN ACCESS]
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** Schmidt, K; Martens-Lobenhoffer, J; Meinitzer, A; Graier, WF; Torres, CM; Venema, RC; Mayer, B Activation of endothelial nitric oxide synthase by the pro-apoptotic drug embelin: Striking discrepancy between nitric oxide-mediated cyclic GMP accumulation and L-citrulline formation.
Nitric Oxide. 2010; 22(4): 281-289. [OPEN ACCESS]
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** Waldeck-Weiermair, M; Duan, X; Naghdi, S; Khan, MJ; Trenker, M; Malli, R; Graier, WF Uncoupling protein 3 adjusts mitochondrial Ca(2+) uptake to high and low Ca(2+) signals.
Cell Calcium. 2010; 48(5): 288-301. [OPEN ACCESS]
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** Waldeck-Weiermair, M; Malli, R; Naghdi, S; Trenker, M; Kahn, MJ; Graier, WF The contribution of UCP2 and UCP3 to mitochondrial Ca(2+) uptake is differentially determined by the source of supplied Ca(2+).
Cell Calcium. 2010; 47(5): 433-440.
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Abstracts (Journal)

** Aflaki, E; Malli, R; Radovic, B; Eisenberg, T; Ring, J; Chandak, PG; Graier, W; Madeo, F; Kratky, D ADIPOSE TRIGLYCERIDE LIPASE DEFICIENCY RESULTS IN MACROPHAGE APOPTOSIS
ATHEROSCLER SUPPL. 2010; 11(2):211--Gordon Research Conference; August 2010; MA, USA. [Oral Communication]
Web of Science

 

2009

Full papers/articles (Journal)

** Graier, WF; Malli, R; Kostner, GM Mitochondrial protein phosphorylation: instigator or target of lipotoxicity?
Trends Endocrinol Metab. 2009; 20(4): 186-193. [OPEN ACCESS]
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Corrections

** Jousset, H; Malli, R; Girardin, N; Graier, WF; Demaurex, N; Frieden, M Evidence for a receptor-activated Ca2+ entry pathway independent from Ca2+ store depletion in endothelial cells (vol 43, pg 83, 2008)
CELL CALCIUM. 2009; 45(1): 98-98.
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Abstracts (Journal)

** Bálint, Z; Zabini, D; Konya, V; Graier, WF; Preissner, KT; Heinemann, A; Olschewski, H; Olschewski, A Alteration of temporal calcium signalling in human pulmonary artery endothelial cells by double-stranded RNA
WIEN KLIN WOCHENSCHR. 2009; 121(17-18):A45-A46.-ÖGP; JUN 11-13, 2009; Salzburg, AUSTRIA. [Oral Communication]
Web of Science

 

** Zabini, D; Bálint, Z; Graier, WF; Hrzenjak, A; Olschewski, H; Olschewski, A Double-stranded RNA affects the TRPC channel expression in human pulmonary artery endothelial cells
WIEN KLIN WOCHENSCHR. 2009; 121(17-18):A57-A58.-ÖGP; JUN 11-13, 2009; Salzburg, AUSTRIA. [Oral Communication]
Web of Science

 

2008

Full papers/articles (Journal)

** Graier, WF; Trenker, M; Malli, R Mitochondrial Ca2+, the secret behind the function of uncoupling proteins 2 and 3?
Cell Calcium. 2008; 44(1): 36-50. [OPEN ACCESS]
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** Jousset, H; Malli, R; Girardin, N; Graier, WF; Demaurex, N; Frieden, M Evidence for a receptor-activated Ca2+ entry pathway independent from Ca2) store depletion in endothelial cells.
Cell Calcium. 2008; 43(1): 83-94.
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** Malli, R; Naghdi, S; Romanin, C; Graier, WF Cytosolic Ca2+ prevents the subplasmalemmal clustering of STIM1: an intrinsic mechanism to avoid Ca2+ overload.
J Cell Sci. 2008; 121(Pt 19): 3133-3139. [OPEN ACCESS]
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** Schweiger, M; Schoiswohl, G; Lass, A; Radner, FP; Haemmerle, G; Malli, R; Graier, W; Cornaciu, I; Oberer, M; Salvayre, R; Fischer, J; Zechner, R; Zimmermann, R The C-terminal region of human adipose triglyceride lipase affects enzyme activity and lipid droplet binding.
J Biol Chem. 2008; 283(25): 17211-17220. [OPEN ACCESS]
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** Trenker, M; Fertschai, I; Malli, R; Graier, WF UCP2/3 - likely to be fundamental for mitochondrial Ca(2+) uniport.
Nat Cell Biol. 2008; 10(11): 1237-1240.
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** Waldeck-Weiermair, M; Zoratti, C; Osibow, K; Balenga, N; Goessnitzer, E; Waldhoer, M; Malli, R; Graier, WF Integrin clustering enables anandamide-induced Ca2+ signaling in endothelial cells via GPR55 by protection against CB1-receptor-triggered repression.
J Cell Sci. 2008; 121(Pt 10): 1704-1717. [OPEN ACCESS]
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Comments

** Graier, WF; Hecker, M Endothelial H2O2: a bad guy turning good?
Arterioscler Thromb Vasc Biol. 2008; 28(10): 1691-1693. [OPEN ACCESS]
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2007

Full papers/articles (Journal)

** Graier, WF; Frieden, M; Malli, R Mitochondria and Ca(2+) signaling: old guests, new functions.
Pflugers Arch. 2007; 455(3): 375-396. [OPEN ACCESS]
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** Malli, R; Frieden, M; Hunkova, M; Trenker, M; Graier, WF Ca2+ refilling of the endoplasmic reticulum is largely preserved albeit reduced Ca2+ entry in endothelial cells.
Cell Calcium. 2007; 41(1): 63-76. [OPEN ACCESS]
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** Trenker, M; Malli, R; Fertschai, I; Levak-Frank, S; Graier, WF Uncoupling proteins 2 and 3 are fundamental for mitochondrial Ca2+ uniport.
Nat Cell Biol. 2007; 9(4): 445-452. [OPEN ACCESS]
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** Wiesenberger, G; Steinleitner, K; Malli, R; Graier, WF; Vormann, J; Schweyen, RJ; Stadler, JA Mg2+ deprivation elicits rapid Ca2+ uptake and activates Ca2+/calcineurin signaling in Saccharomyces cerevisiae.
Eukaryot Cell. 2007; 6(4): 592-599. [OPEN ACCESS]
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2006

Full papers/articles (Journal)

** Osibow, K; Frank, S; Malli, R; Zechner, R; Graier, WF Mitochondria maintain maturation and secretion of lipoprotein lipase in the endoplasmic reticulum.
Biochem J. 2006; 396(1): 173-182. [OPEN ACCESS]
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** Osibow, K; Malli, R; Kostner, GM; Graier, WF A new type of non-Ca2+-buffering Apo(a)-based fluorescent indicator for intraluminal Ca2+ in the endoplasmic reticulum.
J BIOL CHEM. 2006; 281(8): 5017-5025. [OPEN ACCESS]
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Abstracts (Journal)

** Kipmen-Korgun, D; Osibow, K; Zoratti, C; Greilberger, J; Kostner, GM; Juergens, G; Graier, WF T-cadherin mediates low-density lipoprotein-initiated mitogenic signalling
FEBS J. 2006; 273: 94-94. [Poster]
Web of Science

 

2005

Full papers/articles (Journal)

** Kipmen-Korgun, D; Osibow, K; Zoratti, C; Schraml, E; Greilberger, J; Kostner, GM; Jürgens, G; Graier, WF T-cadherin mediates low-density lipoprotein-initiated cell proliferation via the Ca(2+)-tyrosine kinase-Erk1/2 pathway.
J CARDIOVASC PHARMACOL. 2005; 45(5): 418-430. [OPEN ACCESS]
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** Malli, R; Frieden, M; Trenker, M; Graier, WF The role of mitochondria for Ca2+ refilling of the endoplasmic reticulum.
J BIOL CHEM. 2005; 280(13): 12114-12122. [OPEN ACCESS]
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Reviews

** Knot, HJ; Laher, I; Sobie, EA; Guatimosim, S; Gomez-Viquez, L; Hartmann, H; Song, LS; Lederer, WJ; Graier, WF; Malli, R; Frieden, M; Petersen, OH Twenty years of calcium imaging: cell physiology to dye for.
MOL INTERV. 2005; 5(2): 112-127. [OPEN ACCESS]
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2004

Full papers/articles (Journal)

** Bilban, M; Ghaffari-Tabrizi, N; Hintermann, E; Bauer, S; Molzer, S; Zoratti, C; Malli, R; Sharabi, A; Hiden, U; Graier, W; Knöfler, M; Andreae, F; Wagner, O; Quaranta, V; Desoye, G Kisspeptin-10, a KiSS-1/metastin-derived decapeptide, is a physiological invasion inhibitor of primary human trophoblasts.
J CELL SCI. 2004; 117(Pt 8): 1319-1328. [OPEN ACCESS]
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** Graziani, A; Bricko, V; Carmignani, M; Graier, WF; Groschner, K Cholesterol- and caveolin-rich membrane domains are essential for phospholipase A2-dependent EDHF formation.
CARDIOVASC RES. 2004; 64(2): 234-242. [OPEN ACCESS]
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** Marsche, G; Heller, R; Fauler, G; Kovacevic, A; Nuszkowski, A; Graier, W; Sattler, W; Malle, E 2-chlorohexadecanal derived from hypochlorite-modified high-density lipoprotein-associated plasmalogen is a natural inhibitor of endothelial nitric oxide biosynthesis.
ARTERIOSCLER THROMB VASC BIOL. 2004; 24(12): 2302-2306. [OPEN ACCESS]
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** Paltauf-Doburzynska, J; Malli, R; Graier, WF Hyperglycemic conditions affect shape and Ca2+ homeostasis of mitochondria in endothelial cells.
J CARDIOVASC PHARMACOL. 2004; 44(4): 423-436. [OPEN ACCESS]
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Abstracts (Journal)

** Graier, WF Ca2+ regulation of signal transduction in the endothelial cells
J VASC RES 2004 41: 91-91.
Web of Science

 

** Graziani, A; Bricko, V; Graier, WF; Groschner, K Cholesterol- and caveolin-rich membrane domains are essential for phospholipase A(2)-mediated EDHF signaling
NAUNYN-SCHMIED ARCH PHARMACOL 2004 369: R36-R36.
Web of Science

 

2003

Full papers/articles (Journal)

** Artwohl, M; Graier, WF; Roden, M; Bischof, M; Freudenthaler, A; Waldhäusl, W; Baumgartner-Parzer, SM Diabetic LDL triggers apoptosis in vascular endothelial cells.
Diabetes. 2003; 52(5):1240-1247 [OPEN ACCESS]
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** Esenabhalu, VE; Schaeffer, G; Graier, WF Free fatty acid overload attenuates Ca2+ signaling and NO production in endothelial cells.
Antioxid Redox Signal. 2003; 5(2):147-153
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** Malli, R; Frieden, M; Osibow, K; Graier, WF Mitochondria efficiently buffer subplasmalemmal Ca2+ elevation during agonist stimulation.
J Biol Chem. 2003; 278(12):10807-10815 [OPEN ACCESS]
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** Malli, R; Frieden, M; Osibow, K; Zoratti, C; Mayer, M; Demaurex, N; Graier, WF Sustained Ca2+ transfer across mitochondria is Essential for mitochondrial Ca2+ buffering, sore-operated Ca2+ entry, and Ca2+ store refilling.
J Biol Chem. 2003; 278(45):44769-44779 [OPEN ACCESS]
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** Schaeffer, G; Levak-Frank, S; Spitaler, MM; Fleischhacker, E; Esenabhalu, VE; Wagner, AH; Hecker, M; Graier, WF Intercellular signalling within vascular cells under high D-glucose involves free radical-triggered tyrosine kinase activation.
Diabetologia. 2003; 46(6):773-783 [OPEN ACCESS]
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** Zoratti, C; Kipmen-Korgun, D; Osibow, K; Malli, R; Graier, WF Anandamide initiates Ca(2+) signaling via CB2 receptor linked to phospholipase C in calf pulmonary endothelial cells.
Br J Pharmacol. 2003; 140(8):1351-1362 [OPEN ACCESS]
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Abstracts (Journal)

** Artwohl, M; Graier, WF; Roden, M; Bischof, M; Freudenthaler, A; Waldhausl, WK; Baumgartner-Parzer, SM Diabetic low-density lipoprotein triggers apoptosis in vascular endothelial cells.
DIABETOLOGIA 2003 46: 1166-1166.
Web of Science

 

** Graier, W Ca2+ regulation of signal transduction in the endothelium
ATHEROSCLER SUPPL 2003 4: 266-267.
Web of Science

 

2002

Full papers/articles (Journal)

** Bochkov, VN; Mechtcheriakova, D; Lucerna, M; Huber, J; Malli, R; Graier, WF; Hofer, E; Binder, BR; Leitinger, N Oxidized phospholipids stimulate tissue factor expression in human endothelial cells via activation of ERK/EGR-1 and Ca(++)/NFAT.
Blood. 2002; 99(1):199-206 [OPEN ACCESS]
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** Esenabhalu, VE; Cerimagic, M; Malli, R; Osibow, K; Levak-Frank, S; Frieden, M; Sattler, W; Kostner, GM; Zechner, R; Graier, WF Tissue-specific expression of human lipoprotein lipase in the vascular system affects vascular reactivity in transgenic mice.
Br J Pharmacol. 2002; 135(1):143-154 [OPEN ACCESS]
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** Frieden, M; Malli, R; Samardzija, M; Demaurex, N; Graier, WF Subplasmalemmal endoplasmic reticulum controls K(Ca) channel activity upon stimulation with a moderate histamine concentration in a human umbilical vein endothelial cell line.
J Physiol. 2002; 540(Pt 1):73-84 [OPEN ACCESS]
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** Spitaler, MM; Hammer, A; Malli, R; Graier, WF Functional analysis of histamine receptor subtypes involved in endothelium-mediated relaxation of the human uterine artery.
Clin Exp Pharmacol Physiol. 2002; 29(8):711-716
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** Thyagarajan, B; Malli, R; Schmidt, K; Graier, WF; Groschner, K Nitric oxide inhibits capacitative Ca2+ entry by suppression of mitochondrial Ca2+ handling.
Br J Pharmacol. 2002; 137(6):821-830 [OPEN ACCESS]
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** Tiran, A; Gruber, HJ; Graier, WF; Wagner, AH; Van Leeuwen, EB; Tiran, B Aspirin inhibits Chlamydia pneumoniae-induced nuclear factor-kappa B activation, cytokine expression, and bacterial development in human endothelial cells.
Arterioscler Thromb Vasc Biol. 2002; 22(7):1075-1080 [OPEN ACCESS]
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Reviews

** Spitaler, MM; Graier, WF Vascular targets of redox signalling in diabetes mellitus.
Diabetologia. 2002; 45(4):476-494 [OPEN ACCESS]
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2001

Full papers/articles (Journal)

** Bowles, DK; Graier, WF; Sturek, M Hydrogen peroxide activates Na(+)-dependent Ca(2+) influx in coronary endothelial cells.
Biochem Biophys Res Commun. 2001; 287(5):1134-1139
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** Schulter, V; Koolwijk, P; Peters, E; Frank, S; Hrzenjak, A; Graier, WF; van Hinsbergh, VW; Kostner, GM Impact of apolipoprotein(a) on in vitro angiogenesis.
Arterioscler Thromb Vasc Biol. 2001; 21(3):433-438 [OPEN ACCESS]
Web of Science PubMed FullText

 

** Ugdyzhekova, DS; Bernatskaya, NA; Stefano, JB; Graier, VF; Tam, SW; Mekhoulam, R Endogenous cannabinoid anandamide increases heart resistance to arrhythmogenic effects of epinephrine: role of CB(1) and CB(2) receptors.
Bull Exp Biol Med. 2001; 131(3):251-253
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** Zimmermann, R; Panzenböck, U; Wintersperger, A; Levak-Frank, S; Graier, W; Glatter, O; Fritz, G; Kostner, GM; Zechner, R Lipoprotein lipase mediates the uptake of glycated LDL in fibroblasts, endothelial cells, and macrophages.
DIABETES 2001 50: 1643-1653. [OPEN ACCESS]
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Abstracts (Journal)

** Bernhart, E; Fleischhacker, E; Schaffer, P; Pelzmann, B; Skrabal, F; Graier, W; Koidl, B Function of the human vascular smooth muscle cell in hypertension
EUR HEART J 2001 22: 98-98.
Web of Science

 

** Bochkov, VN; Mechtcheriakova, D; Lucerna, M; Huber, J; Malli, R; Graier, WF; Binder, BR; Leitinger, N Oxidized 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine (OxPAPC) stimulates expression of tissue factor in human endothelial cells through activation of ERK/EGR-1 and Ca2+/NFAT
ARTERIOSCLER THROMB VASC BIOL 2001 21: 694-694.
Web of Science FullText FullText_MUG

 

Proceedings Papers

** Paltauf-Doburzynska, J; Kohlwein, SD; Graier, WF Digital imaging of diabetic endothelial cells
P SOC PHOTO-OPT INSTRUM ENG. 2001; 2(17): 1-6.
Web of Science

 

2000

Full papers/articles (Journal)

** Fleischhacker, E; Esenabhalu, VE; Holzmann, S; Skrabal, F; Koidl, B; Kostner, GM; Graier, WF In human hypercholesterolemia increased reactivity of vascular smooth muscle cells is due to altered subcellular Ca(2+) distribution.
Atherosclerosis. 2000; 149(1):33-42
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** Frieden, M; Graier, WF Subplasmalemmal ryanodine-sensitive Ca2+ release contributes to Ca2+-dependent K+ channel activation in a human umbilical vein endothelial cell line.
J Physiol. 2000; 524 Pt 3(1):715-724 [OPEN ACCESS]
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** Lintschinger, B; Balzer-Geldsetzer, M; Baskaran, T; Graier, WF; Romanin, C; Zhu, MX; Groschner, K Coassembly of Trp1 and Trp3 proteins generates diacylglycerol- and Ca2+-sensitive cation channels.
J Biol Chem. 2000; 275(36):27799-27805 [OPEN ACCESS]
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** Paltauf-Doburzynska, J; Frieden, M; Spitaler, M; Graier, WF Histamine-induced Ca2+ oscillations in a human endothelial cell line depend on transmembrane ion flux, ryanodine receptors and endoplasmic reticulum Ca2+-ATPase.
J PHYSIOL-LONDON. 2000; 524 Pt 3(6): 701-713. [OPEN ACCESS]
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** Prattes, S; Hörl, G; Hammer, A; Blaschitz, A; Graier, WF; Sattler, W; Zechner, R; Steyrer, E Intracellular distribution and mobilization of unesterified cholesterol in adipocytes: triglyceride droplets are surrounded by cholesterol-rich ER-like surface layer structures.
J CELL SCI 2000 113: 2977-2989. [OPEN ACCESS]
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Abstracts (Journal)

** Artwohl, M; Graier, W; Roden, M; Ludwig, C; Bischof, M; Baumgartner-Parzer, S Modulation by glycated LDL of apoptosis, proliferation and associated protein expression in vascular endothelial cells
DIABETES 2000 49: A265-A265.
Web of Science

 

** Prattes, S; Horl, G; Hammer, A; Blaschitz, A; Graier, WF; Sattler, W; Zechner, R; Steyrer, E Intracellular distribution and mobilization of unesterified cholesterol in adipocytes.
MOL BIOL CELL 2000 11: 109A-110A.
Web of Science

 

1999

Full papers/articles (Journal)

** Artwohl, M; Graier, W; Roden, M; Waldhausl, W; Baumgartner-Parzer, S Fourth Annual Meeting of the Austrian Society for Endocrinology and Metabolism St. Wolfgang - April 21-24, 1999
WIEN KLIN WOCHENSCHR 1999 111: S2-S20.
Web of Science

 

** Fleischhacker, E; Esenabhalu, VE; Spitaler, M; Holzmann, S; Skrabal, F; Koidl, B; Kostner, GM; Graier, WF Human diabetes is associated with hyperreactivity of vascular smooth muscle cells due to altered subcellular Ca2+ distribution.
Diabetes. 1999; 48(6):1323-1330 [OPEN ACCESS]
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** Graier, WF; Posch, K; Fleischhacker, E; Wascher, TC; Kostner, GM Increased superoxide anion formation in endothelial cells during hyperglycemia: an adaptive response or initial step of vascular dysfunction?
Diabetes Res Clin Pract. 1999; 45(2-3):153-160
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** Mombouli, JV; Holzmann, S; Kostner, GM; Graier, WF Potentiation of Ca2+ signaling in endothelial cells by 11,12-epoxyeicosatrienoic acid.
J Cardiovasc Pharmacol. 1999; 33(5):779-784
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** Mombouli, JV; Schaeffer, G; Holzmann, S; Kostner, GM; Graier, WF Anandamide-induced mobilization of cytosolic Ca2+ in endothelial cells.
Br J Pharmacol. 1999; 126(7):1593-1600 [OPEN ACCESS]
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** Paltauf-Doburzynska, J; Frieden, M; Graier, WF Mechanisms of Ca2+ store depletion in single endothelial cells in a Ca(2+)-free environment.
Cell Calcium. 1999; 25(5):345-353
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** Posch, K; Schmidt, K; Graier, WF Selective stimulation of L-arginine uptake contributes to shear stress-induced formation of nitric oxide.
Life Sci. 1999; 64(8):663-670
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** Posch, K; Simecek, S; Wascher, TC; Jürgens, G; Baumgartner-Parzer, S; Kostner, GM; Graier, WF Glycated low-density lipoprotein attenuates shear stress-induced nitric oxide synthesis by inhibition of shear stress-activated L-arginine uptake in endothelial cells.
Diabetes. 1999; 48(6):1331-1337 [OPEN ACCESS]
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** Schaeffer, G; Wascher, TC; Kostner, GM; Graier, WF Alterations in platelet Ca2+ signalling in diabetic patients is due to increased formation of superoxide anions and reduced nitric oxide production.
Diabetologia. 1999; 42(2):167-176
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Abstracts (Journal)

** Baumgartner-Parzer, S; Artwohl, M; Graier, W; Ludwig, C; Roden, M; Waldhausl, W Lipoproteinlipase modulates glycated LDL induced effects in cultured vascular endothelial cells.
DIABETOLOGIA 1999 42: A326-A326.
Web of Science

 

** Prattes, S; Horl, G; Sattler, W; Graier, WF; Zechner, R; Steyrer, E Triglyceride droplets within adipocytes are surrounded by ER-like, FC-with structures.
MOL BIOL CELL 1999 10: 106A-106A.
Web of Science

 

** Zimmermann, R; Graier, W; Kostner, GM; Zechner, R Lipoprotein lipase stimulates the selective uptake of LDL-cholesteryl esters in endothelial cells
CIRCULATION 1999 100: 256-256.
Web of Science

 

Proceedings Papers

** Graier, WF; Hoebel, BG; Frank, S; Kostner, GM Intracellular action of epoxyeicosatrienoic acids in endothelial cells
ENDOTHELIUM-DEPENDENT HYPERPOLARIZATIONS. 1999; 69-75.
Web of Science

 

** Mombouli, JV; Zeldin, D; Scott-Burden, T; Holzmann, S; Kostner, GM; Graier, WF Epoxyeicosatrienoic acids potentiate Ca2+ signaling in both endothelial and vascular smooth muscle cells
. 1999; 77-83.
Web of Science

 

1998

Full papers/articles (Journal)

** Graier, WF; Hoebel, BG; Paltauf-Doburzynska, J; Kostner, GM Effects of superoxide anions on endothelial Ca2+ signaling pathways.
Arterioscler Thromb Vasc Biol. 1998; 18(9):1470-1479 [OPEN ACCESS]
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** Graier, WF; Paltauf-Doburzynska, J; Hill, BJ; Fleischhacker, E; Hoebel, BG; Kostner, GM; Sturek, M Submaximal stimulation of porcine endothelial cells causes focal Ca2+ elevation beneath the cell membrane.
J Physiol. 1998; 506 ( Pt 1)(4):109-125 [OPEN ACCESS]
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** Hoebel, BG; Graier, WF 11,12-Epoxyeicosatrienoic acid stimulates tyrosine kinase activity in porcine aortic endothelial cells.
Eur J Pharmacol. 1998; 346(1):115-117
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** Hoebel, BG; Steyrer, E; Graier, WF Origin and function of epoxyeicosatrienoic acids in vascular endothelial cells: more than just endothelium-derived hyperpolarizing factor?
CLIN EXP PHARMACOL PHYSIOL 1998 25: 826-830.
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** Paltauf-Doburzynska, J; Posch, K; Paltauf, G; Graier, WF Stealth ryanodine-sensitive Ca2+ release contributes to activity of capacitative Ca2+ entry and nitric oxide synthase in bovine endothelial cells.
J Physiol. 1998; 513 ( Pt 2)(2):369-379 [OPEN ACCESS]
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Abstracts (Journal)

** Fleischhacker, E; Skrabal, F; Holzmann, S; Koidl, B; Graier, WF Hypercholesterolemia and diabetes mellitus in humans are associated with increased smooth muscle contractility due to enhanced formation of superoxide anions resulting in changes in subcellular Ca2+ distribution
CIRCULATION 1998 98: 110-110.
Web of Science

 

** Graier, WF; Paltauf-Doburzynska, J; Posch, K Stealth Ca2+-induced Ca2+ release in the subplasmalemmal area contributes to activation of nitric oxide synthase upon autacoids in human endothelial cells
CIRCULATION 1998 98: 667-667.
Web of Science

 

** Graier, WF; Posch, K; Kostner, GM Glycated LDL attenuates shear stress-induced nitric oxide synthesis by inhibition of shear stress activated L-arginine uptake in endothelial cells
CIRCULATION 1998 98: 37-38.
Web of Science

 

** Prattes, S; Graier, WF; Sattler, W; Zechner, R; Steyrer, E Cholesterol metabolism of adipocytes: Efflux of free cholesterol.
MOL BIOL CELL 1998 9: 92A-92A.
Web of Science

 

1997

Full papers/articles (Journal)

** Graier, WF; Posch, K; Wascher, TC; Kostner, GM Role of superoxide anions in changes of endothelial vasoactive response during acute hyperglycemia.
Horm Metab Res. 1997; 29(12):622-626
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** Graier, WF; Simecek, S; Hoebel, BG; Wascher, TC; Dittrich, P; Kostner, GM Antioxidants prevent high-D-glucose-enhanced endothelial Ca2+/cGMP response by scavenging superoxide anions.
Eur J Pharmacol. 1997; 322(1):113-122
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** Hoebel, BG; Kostner, GM; Graier, WF Activation of microsomal cytochrome P450 mono-oxygenase by Ca2+ store depletion and its contribution to Ca2+ entry in porcine aortic endothelial cells.
Br J Pharmacol. 1997; 121(8):1579-1588 [OPEN ACCESS]
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** Paltauf-Doburzynska, J; Graier, WF Temperature dependence of agonist-stimulated Ca2+ signaling in cultured endothelial cells.
Cell Calcium. 1997; 21(1):43-51
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** Wascher, TC; Graier, WF; Dittrich, P; Hussain, MA; Bahadori, B; Wallner, S; Toplak, H Effects of low-dose L-arginine on insulin-mediated vasodilatation and insulin sensitivity.
Eur J Clin Invest. 1997; 27(8):690-695
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** Wascher, TC; Posch, K; Wallner, S; Hermetter, A; Kostner, GM; Graier, WF Vascular effects of L-arginine: anything beyond a substrate for the NO-synthase?
Biochem Biophys Res Commun. 1997; 234(1):35-38
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Editorials

** Graier, WF; Kostner, GM Glycated low-density lipoprotein and atherogenesis: the missing link between diabetes mellitus and hypercholesterolaemia?
Eur J Clin Invest. 1997; 27(6):457-459
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Abstracts (Journal)

** Graier, WF; Posch, K; Kostner, GM Effect of Glycated LDL on endothelial free radical release and its relevance for vascular dysfunction
ATHEROSCLEROSIS 1997 130: 4-4.
Web of Science

 

** SchirgiDegen, A; Graier, W; Beubler, E Involvement of nitric oxide in intestinal absorption induced by morphine and loperamide.
NAUNYN-SCHMIED ARCH PHARMACOL 1997 355: 394-394.
Web of Science

 

1996

Full papers/articles (Journal)

** Graier, WF; Holzmann, S; Hoebel, BG; Kukovetz, WR; Kostner, GM Mechanisms of L-NG nitroarginine/indomethacin-resistant relaxation in bovine and porcine coronary arteries.
Br J Pharmacol. 1996; 119(6):1177-1186 [OPEN ACCESS]
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** Graier, WF; Simecek, S; Kukovetz, WR; Kostner, GM High D-glucose-induced changes in endothelial Ca2+/EDRF signaling are due to generation of superoxide anions.
Diabetes. 1996; 45(10):1386-1395 [OPEN ACCESS]
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** He, GW; Yang, CQ; Graier, WF; Yang, JA Hyperkalemia alters EDHF-mediated hyperpolarization and relaxation in coronary arteries.
AMER J PHYSIOL-HEART CIRC PHY. 1996; 271(2 Pt 2): H760-H767. [OPEN ACCESS]
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** Wascher, TC; Bachernegg, M; Kickenweiz, A; Stark, G; Stark, U; Toplak, H; Graier, WF Involvement of the L-arginine-nitric oxide pathway in hyperglycaemia-induced coronary artery dysfunction of isolated guinea pig hearts.
Eur J Clin Invest. 1996; 26(8):707-712
Web of Science PubMed FullText

 

Abstracts (Journal)

** Beubler, E; SchirgiDegen, A; Hammer, S; Graier, W Nitric oxide mediates the proabsorptive effect of morphine in the rat jejunum.
GASTROENTEROLOGY 1996 110: A312-A312.
Web of Science

 

** Graier, WF; Simecek, S; Hoebel, HG; Wascher, TC; Kostner, GM High-D-glucose-induced changes in endothelial Ca2+/EDRF signaling is due to generation of superoxide anions
DIABETOLOGIA 1996 39: 526-526.
Web of Science

 

** HabersackWallner, S; Kreuz, E; Graier, WF; Bahadori, B; Toplak, H; Wascher, TC Superoxide scavenging effects of free aminoacids
DIABETOLOGIA 1996 39: 855-855.
Web of Science

 

** Wascher, TC; Graier, WF; Bahadori, B; Toplak, H Effects of L-arginine on insulin-mediated vasodilation and insulin sensitivity in NIDDM and obesity.
DIABETOLOGIA 1996 39: 575-575.
Web of Science

 

1995

Full papers/articles (Journal)

** Brunner, F; Stessel, H; Graier, WF The effects of intracellular Ca2+ concentration and hypoxia on basal endothelin-1 secretion by cultured porcine aortic endothelial cells.
Agents Actions Suppl. 1995; 45:269-273
PubMed Google Scholar

 

** Graier, WF; Grubenthal, I; Dittrich, P; Wascher, TC; Kostner, GM Intracellular mechanism of high D-glucose-induced modulation of vascular cell proliferation.
Eur J Pharmacol. 1995; 294(1):221-229
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** Graier, WF; Simecek, S; Sturek, M Cytochrome P450 mono-oxygenase-regulated signalling of Ca2+ entry in human and bovine endothelial cells.
J Physiol. 1995; 482 ( Pt 2)(3):259-274 [OPEN ACCESS]
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** Wascher, TC; Bachernegg, M; Kickenweiz, E; Stark, G; Stark, U; Toplak, H; Graier, WF; Krejs, GJ Elevation of D-glucose impairs coronary artery autoregulation after slight reduction of coronary flow.
Eur J Clin Invest. 1995; 25(8):590-594
Web of Science PubMed

 

Letters

** Toplak, H; Graier, W; Dittrich, P; Wiesmann, UN; Wascher, TC Insulin resistance and membrane abnormalities.
LANCET . 1995; 345(8955): 995; author reply 995-995; author reply 996.
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Abstracts (Journal)

** GRAIER, WF; HOLZMANN, S; HOEBEL, BG; KUKOVETZ, WR L(OMEGA)N-NITRO-ARGININE RESISTANT VESSEL RELAXATION IS MEDIATED VIA A PERTUSSIS-TOXIN-SENSITIVE PATHWAY BUT NOT VIA A CYTOCHROME-P450 MONOOXYGENASE IN BOVINE CORONARY-ARTERIES
CIRCULATION 1995 92: 3610-3610.
Web of Science

 

** GRAIER, WF; SIMECEK, S; WASCHER, TC; HOLZMANN, S; KUKOVETZ, WR; KOSTNER, GM THE ALDOSE-REDUCTASE INHIBITOR, ZOPOLRESTAT, AMPLIFIES BLOOD-VESSEL RELAXATION BY INHIBITION OF CGMP-SPECIFIC PHOSPHODIESTERASE
DIABETOLOGIA 1995 38: A262-A262.
Web of Science

 

** WASCHER, TC; GRAIER, WF; BAHADORI, B; TOPLAK, H L-ARGININE IMPROVES INSULIN-RESISTANCE IN OBESE PATIENTS WITH NON-INSULIN-DEPENDENT DIABETES-MELLITUS
DIABETOLOGIA 1995 38: A158-A158.
Web of Science

 

1994

Full papers/articles (Journal)

** Brunner, F; Stessel, H; Simecek, S; Graier, W; Kukovetz, WR Effect of intracellular Ca2+ concentration on endothelin-1 secretion.
FEBS Lett. 1994; 350(1):33-36
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** Graier, WF; Myers, PR; Rubin, LJ; Adams, HR; Parker, JL Escherichia coli endotoxin inhibits agonist-mediated cytosolic Ca2+ mobilization and nitric oxide biosynthesis in cultured endothelial cells.
Circ Res. 1994; 75(4):659-668 [OPEN ACCESS]
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** GRAIER, WF; SIMECEK, S; BOWLES, DK; STUREK, M HETEROGENEITY OF CAFFEINE-SENSITIVE AND BRADYKININ-SENSITIVE CA2+ STORES IN VASCULAR ENDOTHELIAL-CELLS
BIOCHEM J. 1994; 300: 637-641. [OPEN ACCESS]
Web of Science PubMed PUBMED Central

 

** Groschner, K; Graier, WF; Kukovetz, WR Histamine induces K+, Ca2+, and Cl- currents in human vascular endothelial cells. Role of ionic currents in stimulation of nitric oxide biosynthesis.
Circ Res. 1994; 75(2):304-314 [OPEN ACCESS]
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** Holzmann, S; Kukovetz, WR; Windischhofer, W; Paschke, E; Graier, WF Pharmacologic differentiation between endothelium-dependent relaxations sensitive and resistant to nitro-L-arginine in coronary arteries.
J Cardiovasc Pharmacol. 1994; 23(5):747-756
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** Wascher, TC; Toplak, H; Krejs, GJ; Simecek, S; Kukovetz, WR; Graier, WF Intracellular mechanisms involved in D-glucose-mediated amplification of agonist-induced Ca2+ response and EDRF formation in vascular endothelial cells.
Diabetes. 1994; 43(8):984-991
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Letters

** Wascher, TC; Dittrich, P; Toplak, H; Graier, WG Endothelial dysfunction in hypertension.
Lancet. 1994; 344(8921):549-550
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** Wascher, TC; Graier, WF; Bahadori, B; Toplak, H Time course of endothelial dysfunction in diabetes mellitus.
Circulation. 1994; 90(2):1109-1110 [OPEN ACCESS]
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Abstracts (Journal)

** GRAIER, WF; SIMECEK, S; WASCHER, TC; KUKOVETZ, WR; KOSTNER, GM BIDIRECTIONAL EFFECTS OF GLYCATED LDL ON ENDOTHELIAL VASCULAR FUNCTION
CIRCULATION. 1994; 90(4): 29-29.
Web of Science

 

** GRAIER, WF; STUREK, M REGULATION OF ENDOTHELIAL-CELL CA2+ INFLUX BY CYTOCHROME-P450 MECHANISMS
BIOPHYS J. 1994; 66(2): A50-A50.
Web of Science

 

** TOPLAK, H; WASCHER, TC; GRUBENTHAL, I; DITTRICH, P; GRAIER, WF; KREJS, GJ AMINOGUANIDINE REESTABLISHES VASCULAR ENDOTHELIAL-CELL REPARATIVE POTENCY UNDER HYPERGLYCEMIC CONDITIONS
DIABETOLOGIA. 1994; 37: A54-A54.
Web of Science

 

** WASCHER, TC; BACHERNEGG, M; STARK, G; TOPLAK, H; DITTRICH, P; GRAIER, WF; KREJS, GJ VASODILATION INDUCED BY SLIGHT HYPOXIA UNDER HYPERGLYCEMIC CONDITIONS DEPENDS ON THE AVAILABILITY OF L-ARGININE
DIABETOLOGIA. 1994; 37: A23-A23.
Web of Science

 

1993

Full papers/articles (Journal)

** Graier, WF; Kukovetz, WR; Groschner, K Cyclic AMP enhances agonist-induced Ca2+ entry into endothelial cells by activation of potassium channels and membrane hyperpolarization.
Biochem J. 1993; 291 ( Pt 1)(6):263-267 [OPEN ACCESS]
Web of Science PubMed PUBMED Central Google Scholar

 

** Graier, WF; Wascher, TC; Lackner, L; Toplak, H; Krejs, GJ; Kukovetz, WR Exposure to elevated D-glucose concentrations modulates vascular endothelial cell vasodilatory response.
Diabetes. 1993; 42(10):1497-1505
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Abstracts (Journal)

** WASCHER, TC; LACKNER, L; TOPLAK, H; GRAIER, WF MECHANISMS OF GLUCOSE-MEDIATED INCREASES IN THE FORMATION OF ENDOTHELIUM-DERIVED-RELAXING-FACTOR
DIABETOLOGIA. 1993; 36: A12-A12.
Web of Science

 

1992

Full papers/articles (Journal)

** Graier, WF; Groschner, K; Schmidt, K; Kukovetz, WR Increases in endothelial cyclic AMP levels amplify agonist-induced formation of endothelium-derived relaxing factor (EDRF).
Biochem J. 1992; 288 ( Pt 2)(6):345-349 [OPEN ACCESS]
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** Graier, WF; Groschner, K; Schmidt, K; Kukovetz, WR SK&F 96365 inhibits histamine-induced formation of endothelium-derived relaxing factor in human endothelial cells.
Biochem Biophys Res Commun. 1992; 186(3):1539-1545
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** Graier, WF; Schmidt, K; Kukovetz, WR Is the bradykinin-induced Ca2+ influx and the formation of endothelium-derived relaxing factor mediated by a G protein?
Eur J Pharmacol. 1992; 225(1):43-49
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** Groschner, K; Graier, WF; Kukovetz, WR Activation of a small-conductance Ca(2+)-dependent K+ channel contributes to bradykinin-induced stimulation of nitric oxide synthesis in pig aortic endothelial cells.
Biochim Biophys Acta. 1992; 1137(2):162-170
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** Kukovetz, WR; Graier, WF; Groschner, K Contribution of agonist-induced hyperpolarization to Ca2+ influx and formation of EDRF in vascular endothelial cells.
Jpn J Pharmacol. 1992; 58 Suppl 2:213P-2219
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** Schmidt, K; Klatt, P; Graier, WF; Kostner, GM; Kukovetz, WR High-density lipoprotein antagonizes the inhibitory effects of oxidized low-density lipoprotein and lysolecithin on soluble guanylyl cyclase.
Biochem Biophys Res Commun. 1992; 182(1):302-308
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1991

Full papers/articles (Journal)

** Graier, WF; Schmidt, K; Kukovetz, WR Bradykinin-induced Ca(2+)-influx into cultured aortic endothelial cells is not regulated by inositol 1,4,5-trisphosphate or inositol 1,3,4,5-tetrakisphosphate.
Second Messengers Phosphoproteins. 1991; 13(4):187-197
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** GRAIER, WF; SCHMIDT, K; KUKOVETZ, WR ACTIVATION OF G-PROTEIN EVOKES CA2+ INFLUX IN ENDOTHELIAL-CELLS WITHOUT CORRELATION TO INOSITOL PHOSPHATES
J CARDIOVASC PHARMACOL. 1991; 17: S71-S78.
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** Schmidt, K; Graier, WF; Kostner, GM; Mayer, B; Bohme, E; Kukovetz, WR Stimulation of Soluble Guanylate-Cyclase by Endothelium-Derived Relaxing Factor Is Antagonized by Oxidized Low-Density-Lipoprotein
J CARDIOVASC PHARMACOL 1991 17: S83-S88.
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** Schmidt, K; Graier, WF; Kostner, GM; Mayer, B; Böhme, E; Kukovetz, WR Oxidized low-density lipoprotein antagonizes the activation of purified soluble guanylate cyclase by endothelium-derived relaxing factor but does not interfere with its biosynthesis.
Cell Signal. 1991; 3(4):361-367
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1990

Full papers/articles (Journal)

** Graier, WF; Schmidt, K; Kukovetz, WR Effect of sodium fluoride on cytosolic free Ca2(+)-concentrations and cGMP-levels in endothelial cells.
Cell Signal. 1990; 2(4):369-375
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** Schmidt, K; Graier, WF; Kostner, GM; Mayer, B; Kukovetz, WR Activation of soluble guanylate cyclase by nitrovasodilators is inhibited by oxidized low-density lipoprotein.
Biochem Biophys Res Commun. 1990; 172(2):614-619
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** SCHMIDT, K; GRAIER, WF; KUKOVETZ, WR EDRF-formation increases cGMP-levels in cultured endothelial cells.
Adv Second Messenger Phosphoprotein Res. 1990; 24(1):455-460
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