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Trauner Michael |

** = Publications listed in SCI/SSCI/Pubmed

2022

Full paper/article (Journal)

** Fuchs, CD; Dixon, ED; Hendrikx, T; Mlitz, V; Wahlstrom, A; Stahlman, M; Scharnagl, H; Stojakovic, T; Binder, CJ; Marschall, HU; Trauner, M Tetrahydroxylated bile acids improve cholestatic liver and bile duct injury in the Mdr2(-/-) mouse model of sclerosing cholangitis via immunomodulatory effects
HEPATOL COMMUN. 2022; Doi: 10.1002/hep4.1998 [OPEN ACCESS]
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** Fuchs, CD; Radun, R; Dixon, ED; Mlitz, V; Timelthaler, G; Halilbasic, E; Herac, M; Jonker, JW; Ronda, OAHO; Tardelli, M; Haemmerle, G; Zimmermann, R; Scharnagl, H; Stojakovic, T; Verkade, HJ; Trauner, M Hepatocyte-specific deletion of adipose triglyceride lipase (adipose triglyceride lipase/patatin-like phospholipase domain containing 2) ameliorates dietary induced steatohepatitis in mice.
Hepatology. 2022; 75(1):125-139 Doi: 10.1002/hep.32112
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** Hartl, L; Tatscher, E; Weiss, M; Balcar, L; Strassl, R; Jachs, M; Mandorfer, M; Soliman, T; Stadlbauer, V; Schemmer, P; Berlakovich, G; Tilg, H; Schneeberger, S; Trauner, M; Fickert, P; Reiberger, T; Graziadei, I The impact of COVID-19 on liver transplantation programs in Austria.
Wien Klin Wochenschr. 2022; 134(23-24):875-882 Doi: 10.1007/s00508-022-02105-z [OPEN ACCESS]
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** Remetic, J; Ghallab, A; Hobloss, Z; Brackhagen, L; Hassan, R; Myllys, M; Radun, R; Mlitz, V; Zhu, C; Baumgartner, M; Schrottmaier, WC; Mussbacher, M; Timelthaler, G; Scharnagl, H; Stojakovic, T; Assinger, A; Fuchs, CD; Hengstler, JG; Trauner, M Loss of bile salt export pump aggravates lipopolysaccharide-induced liver injury in mice due to impaired hepatic endotoxin clearance.
Hepatology. 2021; Doi: 10.1002/hep.32289 [OPEN ACCESS]
Web of Science PubMed FullText FullText_MUG

 

Abstract (Journal)

** Dixon, ED; Nardo, AD; Claudel, T; Fuchs, C; Mlitz, V; Stojakovic, T; Scharnagl, H; Grabner, G; Zimmermann, R; Trauner, M Chemical suppression of adipose triglyceride lipase improves non-alcoholic steatohepatitis in a diabetic and hyperlipidemic mouse model
J HEPATOL. 2022; 77: S688-S689. [Poster]
Web of Science

 

** Fuchs, C; Dixon, ED; Konigshofer, P; Mlitz, V; Scharnagl, H; Stojakovic, T; Reiberger, T; Trauner, M Loss of bile salt export pump (BSEP/ABCB11) protects mice from development of carbon tetrachloride (CCl4) induced hepatic fibrosis
J HEPATOL. 2022; 77: S469-S469. [Poster]
Web of Science

 

** Munda, P; Tulaeva, I; Stauber, RE; Gattringer, P; Trauner, M; Brunar, H; Valenta, R; Ferenci, P Induction of pre-s antobodies in HBeAg negative chronic hepatitis B patients by thereupatic vaccination with the pre-s based vaccine VVX001-interim analysis
J HEPATOL. 2022; 77: S854-S854.-EASL Annual Meeting; JUN 22-26, 2022; London, UK. [Poster]
Web of Science

 

** Staufer, K; Huber, H; Zessner-Spitzenberg, J; Stauber, RE; Finkenstedt, A; Bantel, H; Weiss, T; Huber, M; Starlinger, P; Grunberger, T; Reiberger, T; Sebens, S; McIntyre, G; Tabibiazar, R; Giaccia, A; Zoller, H; Trauner, M; Mikulits, W Large-scale multicenter study for the clinical utility of the non-invasive biomarkers Gas6 and soluble Axl in hepatocellular carcinoma, liver fibrosis and end-stage liver disease
J HEPATOL. 2022; 77: S470-S470.-EASL Annual Meeting; JUN 22-26, 2022; London, UK. [Poster]
Web of Science

 

2021

Full paper/article (Journal)

** Geier, A; Tiniakos, D; Denk, H; Trauner, M From the origin of NASH to the future of metabolic fatty liver disease
GUT. 2021; 70(8): 1570-1579. Doi: 10.1136/gutjnl-2020-323202 [OPEN ACCESS]
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** Herz, CT; Kulterer, OC; Prager, M; Langer, FB; Prager, G; Marculescu, R; Fauler, G; Hacker, M; Kautzky-Willer, A; Trauner, M; Haug, AR; Kiefer, FW Characterization of endogenous bile acid composition in individuals with cold-activated brown adipose tissue
MOL CELL ENDOCRINOL. 2021; 536: 111403 Doi: 10.1016/j.mce.2021.111403
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** Mózes, FE; Lee, JA; Selvaraj, EA; Jayaswal, ANA; Trauner, M; Boursier, J; Fournier, C; Staufer, K; Stauber, RE; Bugianesi, E; Younes, R; Gaia, S; Lupșor-Platon, M; Petta, S; Shima, T; Okanoue, T; Mahadeva, S; Chan, WK; Eddowes, PJ; Hirschfield, GM; Newsome, PN; Wong, VW; de, Ledinghen, V; Fan, J; Shen, F; Cobbold, JF; Sumida, Y; Okajima, A; Schattenberg, JM; Labenz, C; Kim, W; Lee, MS; Wiegand, J; Karlas, T; Yılmaz, Y; Aithal, GP; Palaniyappan, N; Cassinotto, C; Aggarwal, S; Garg, H; Ooi, GJ; Nakajima, A; Yoneda, M; Ziol, M; Barget, N; Geier, A; Tuthill, T; Brosnan, MJ; Anstee, QM; Neubauer, S; Harrison, SA; Bossuyt, PM; Pavlides, M, , LITMUS, Investigators Diagnostic accuracy of non-invasive tests for advanced fibrosis in patients with NAFLD: an individual patient data meta-analysis.
Gut. 2021; Doi: 10.1136/gutjnl-2021-324243 [OPEN ACCESS]
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** Reich, M; Spomer, L; Klindt, C; Fuchs, K; Stindt, J; Deutschmann, K; Höhne, J; Liaskou, E; Hov, JR; Karlsen, TH; Beuers, U; Verheij, J; Ferreira-Gonzalez, S; Hirschfield, G; Forbes, SJ; Schramm, C; Esposito, I; Nierhoff, D; Fickert, P; Fuchs, CD; Trauner, M; García-Beccaria, M; Gabernet, G; Nahnsen, S; Mallm, JP; Vogel, M; Schoonjans, K; Lautwein, T; Köhrer, K; Häussinger, D; Luedde, T; Heikenwalder, M; Keitel, V Downregulation of TGR5 (GPBAR1) in biliary epithelial cells contributes to the pathogenesis of sclerosing cholangitis.
J Hepatol. 2021; 75(3):634-646 Doi: 10.1016/j.jhep.2021.03.029
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** Schinagl, M; Tomin, T; Gindlhuber, J; Honeder, S; Pfleger, R; Schittmayer, M; Trauner, M; Birner-Gruenberger, R Proteomic Changes of Activated Hepatic Stellate Cells.
Int J Mol Sci. 2021; 22(23): Doi: 10.3390/ijms222312782 [OPEN ACCESS]
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** Skok, K; Stelzl, E; Trauner, M; Kessler, HH; Lax, SF Post-mortem viral dynamics and tropism in COVID-19 patients in correlation with organ damage.
VIRCHOWS ARCH. 2021; 478(2): 343-353. Doi: 10.1007/s00428-020-02903-8 [OPEN ACCESS]
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** Skok, K; Vander, K; Setaffy, L; Kessler, HH; Aberle, S; Bargfrieder, U; Trauner, M; Lax, SF COVID-19 autopsies: Procedure, technical aspects and cause of fatal course. Experiences from a single-center.
PATHOL RES PRACT. 2021; 217: 153305-153305. Doi: 10.1016/j.prp.2020.153305 [OPEN ACCESS]
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** Tardelli, M; Bruschi, FV; Fuchs, CD; Claudel, T; Auer, N; Kunczer, V; Ronda, OAHO; Verkade, HJ; Stojakovic, T; Scharnagl, H; Trauner, M Absence of Adiponutrin (PNPLA3) and Monoacylglycerol Lipase Synergistically Increases Weight Gain and Aggravates Steatohepatitis in Mice.
Int J Mol Sci. 2021; 22(4): Doi: 10.3390/ijms22042126 [OPEN ACCESS]
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** Traussnigg, S; Halilbasic, E; Hofer, H; Munda, P; Stojakovic, T; Fauler, G; Kashofer, K; Krssak, M; Wolzt, M; Trauner, M Open-label phase II study evaluating safety and efficacy of the non-steroidal farnesoid X receptor agonist PX-104 in non-alcoholic fatty liver disease.
Wien Klin Wochenschr. 2021; 133(9-10):441-451 Doi: 10.1007/s00508-020-01735-5 [OPEN ACCESS]
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** Zhu, C; Boucheron, N; Müller, AC; Májek, P; Claudel, T; Halilbasic, E; Baazim, H; Lercher, A; Viczenczova, C; Hainberger, D; Preglej, T; Sandner, L; Alteneder, M; Gülich, AF; Khan, M; Hamminger, P; Remetic, J; Ohradanova-Repic, A; Schatzlmaier, P; Donner, C; Fuchs, CD; Stojakovic, T; Scharnagl, H; Sakaguchi, S; Weichhart, T; Bergthaler, A; Stockinger, H; Ellmeier, W; Trauner, M 24-Norursodeoxycholic acid reshapes immunometabolism in CD8⁺ T cells and alleviates hepatic inflammation.
J Hepatol. 2021; 75(5):1164-1176 Doi: 10.1016/j.jhep.2021.06.036 [OPEN ACCESS]
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Review

** Lax, SF; Skok, K; Zechner, PM; Setaffy, L; Kessler, HH; Kaufmann, N; Vander, K; Cokić, N; Maierhofer, U; Bargfrieder, U; Trauner, M [Systemic consequences and clinical aspects of SARS-CoV-2 infection].
PATHOLOGE. 2021; 42(2): 155-163. Doi: 10.1007/s00292-021-00913-0 [OPEN ACCESS]
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** Nardo, AD; Schneeweiss-Gleixner, M; Bakail, M; Dixon, ED; Lax, SF; Trauner, M Pathophysiological mechanisms of liver injury in COVID-19.
Liver Int. 2021; 41(1):20-32 Doi: 10.1111/liv.14730 [OPEN ACCESS]
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Correspondence

** Lax, SF; Skok, K; Zechner, PM; Trauner, M Pulmonary Arterial Thrombosis in COVID-19 With Fatal Outcome.
Ann Intern Med. 2021; 174(1):139-140 Doi: 10.7326/L20-1276
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Correction

** Hofer, H; Willheim-Polli, C; Knoflach, P; Gabriel, C; Vogel, W; Trauner, M; Müller, T; Ferenci, P Correction: Identification of a novel Wilson disease gene mutation frequent in Upper Austria: a genetic and clinical study.
J Hum Genet. 2021; 66(12):1199 Doi: 10.1038/s10038-021-00918-w
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Abstract (Journal)

** Mozes, F; Lee, J; Selvaraj, E; Jayaswal, A; Trauner, M; Boursier, J; Fournier, C; Staufer, K; Stauber, R; Bugianesi, E; Younes, R; Gaia, S; Lupsor-Platon, M; Petta, S; Shima, T; Okanoue, T; Mahadeva, S; Chan, WK; Eddowes, P; Newsome, PN; Wong, VWS; de Ledinghen, V; Fan, JG; Shen, F; Cobbold, J; Sumida, Y; Okajima, A; Schattenberg, J; Labenz, C; Kim, W; Lee, MS; Wiegand, J; Karlas, T; Yilmaz, Y; Aithal, G; Palaniyappan, N; Cassinotto, C; Aggarwal, S; Harshit, G; Ooi, G; Nakajima, A; Yoneda, M; Ziol, M; Barget, N; Geier, A; Tunill, T; Brosnan, MJ; Anstee, Q; Neubauer, S; Harrison, S; Bossuyt, P; Pavlides, M Individual patient data meta-analysis of the diagnostic performance of single and sequentially combined non-invasive tests in detecting advanced fibrosis
J HEPATOL. ILC 2021 Abstracts. 2021; 75: S259-S260.-The International Liver Congress; JUN 23-26, 2021; Virtuell. [Poster]
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2020

Full paper/article (Journal)

** Fuchs, CD; Krivanec, S; Steinacher, D; Mlitz, V; Wahlström, A; Stahlman, M; Claudel, T; Scharnagl, H; Stojakovic, T; Marschall, HU; Trauner, M Absence of Bsep/Abcb11 attenuates MCD diet-induced hepatic steatosis but aggravates inflammation in mice.
Liver Int. 2020; 40(6):1366-1377 Doi: 10.1111/liv.14423 [OPEN ACCESS]
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** Nardo, AD; Grün, NG; Zeyda, M; Dumanic, M; Oberhuber, G; Rivelles, E; Helbich, TH; Markgraf, DF; Roden, M; Claudel, T; Trauner, M; Stulnig, TM Impact of osteopontin on the development of non-alcoholic liver disease and related hepatocellular carcinoma.
Liver Int. 2020; 40(7):1620-1633 Doi: 10.1111/liv.14464 [OPEN ACCESS]
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** Paternostro, R; Pfeiffenberger, J; Ferenci, P; Stättermayer, AF; Stauber, RE; Wrba, F; Longerich, T; Lackner, K; Trauner, M; Ferlitsch, A; Reiberger, T; Weiss, KH Non-invasive diagnosis of cirrhosis and long-term disease monitoring by transient elastography in patients with Wilson disease.
Liver Int. 2020; 40(4):894-904 Doi: 10.1111/liv.14368 [OPEN ACCESS]
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** Tardelli, M; Bruschi, FV; Fuchs, CD; Claudel, T; Auer, N; Kunczer, V; Baumgartner, M; Ronda, OAHO; Jan Verkade, H; Stojakovic, T; Scharnagl, H; Habib, A; Zimmermann, R; Lotersztajn, S; Trauner, M Monoacylglycerol lipase inhibition protects from liver injury in mouse models of sclerosing cholangitis.
Hepatology. 2020; Doi: 10.1002/hep.30929 [OPEN ACCESS]
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** Wagner, C; Hois, V; Pajed, L; Pusch, LM; Wolinski, H; Trauner, M; Zimmermann, R; Taschler, U; Lass, A Lysosomal acid lipase is the major acid retinyl ester hydrolase in cultured human hepatic stellate cells but not essential for retinyl ester degradation.
Biochim Biophys Acta Mol Cell Biol Lipids. 2020; 1865(8): 158730-158730. Doi: 10.1016/j.bbalip.2020.158730 [OPEN ACCESS]
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Abstract (Journal)

** Burbaum, B; Schneider, C; Hamesch, K; Fromme, M; Mandorfer, M; Reichert, M; Arslanow, A; Woditsch, V; Bals, R; Pereira, V; Carvao, J; Lammert, F; Trauner, M; Krag, A; Denk, H; Trautwein, C; Strnad, P European Study: Heterozygous Alpha-1-Antitrypsin Deficiency (Pi*MZ) genetic Risk Factor for Hepatopathy.
INTERNIST. Abstracts zum 126. Kongress der Deutschen Gesellschaft für Innere Medizin e.V.. 2020; 61(SUPPL 1):S5-S6.-126. Kongress der Deutschen Gesellschaft für Innere Medizin e.V.; APR 25-28, 2020; Wiesbaden, GERMANY. [Poster]
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2019

Full paper/article (Journal)

** Al-Dury, S; Wahlström, A; Panzitt, K; Thorell, A; Ståhlman, M; Trauner, M; Fickert, P; Bäckhed, F; Fändriks, L; Wagner, M; Marschall, HU Obeticholic acid may increase the risk of gallstone formation in susceptible patients.
J Hepatol. 2019; 71(5):986-991 Doi: 10.1016/j.jhep.2019.06.011
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** Ferenci, P; Pfeiffenberger, J; Stättermayer, AF; Stauber, RE; Willheim, C; Weiss, KH; Munda-Steindl, P; Trauner, M; Schilsky, M; Zoller, H HSD17B13 truncated variant is associated with a mild hepatic phenotype in Wilson's Disease.
JHEP Rep. 2019; 1(1): 2-8. Doi: 10.1016/j.jhepr.2019.02.007 [OPEN ACCESS]
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** Staufer, K; Halilbasic, E; Spindelboeck, W; Eilenberg, M; Prager, G; Stadlbauer, V; Posch, A; Munda, P; Marculescu, R; Obermayer-Pietsch, B; Stift, J; Lackner, C; Trauner, M; Stauber, RE Evaluation and comparison of six noninvasive tests for prediction of significant or advanced fibrosis in nonalcoholic fatty liver disease
UNITED EUR GASTROENT. 2019; UNSP 2050640619865133 Doi: 10.1177/2050640619865133 [OPEN ACCESS]
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** Traussnigg, S; Schattenberg, JM; Demir, M; Wiegand, J; Geier, A; Teuber, G; Hofmann, WP; Kremer, AE; Spreda, F; Kluwe, J; Petersen, J; Boettler, T; Rainer, F; Halilbasic, E; Greinwald, R; Pröls, M; Manns, MP; Fickert, P; Trauner, M; Austrian/German NAFLD-norUDCA study group Norursodeoxycholic acid versus placebo in the treatment of non-alcoholic fatty liver disease: a double-blind, randomised, placebo-controlled, phase 2 dose-finding trial.
Lancet Gastroenterol Hepatol. 2019; 4(10):781-793 Doi: 10.1016/S2468-1253(19)30184-0
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Abstract (Journal)

** Bruschi, F; Tardelli, M; Claudel, T; Zimmermann, R; Lotersztajn, S; Trauner, M Lack of monoacylglycerol lipase protects from MCD-induced hepatic inflammation and fibrosis
J HEPATOL. International Liver Congress / 54th Annual Meeting of the European-Association-for-the-Study-of-the-Liver (EASL). 2019; 70(1):E58-E58.-International Liver Congress / 54th Annual Meeting of the European-Association-for-the-Study-of-the-Liver (EASL); APR 10-14, 2019; Vienna, AUSTRIA. Doi: 10.1016/S0618-8278(19)30104-5 [Poster]
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** Fuchs, C; Mlitz, V; Tardelli, M; Remetic, J; Menz, M; Paumgartner, G; Wolfrum, S; Wahlstrom, A; Stahlman, M; Stojakovic, T; Wolfrum, C; Marschall, HU; Trauner, M Absence of BSEP (ABCB11) protects MDR2 (ABCB4) KO mice from cholestatic liver and bile duct injury through anti-inflammatory bile acid composition and signaling
J HEPATOL. 2019; 70: E163-E164. Doi: 10.1016/S0618-8278(19)30291-9 [Poster]
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** Menz, M; Hinterleitner, L; Konigshofer, P; Halilbasic, E; Kunczer, V; Stojakovic, T; Reiberger, T; Fuchs, C; Trauner, M Glucagon like peptide-2 treatment improves liver and bile duct injury in the Mdr2-/- mouse model of sclerosing cholangitis
J HEPATOL. 2019; 70: E167-E168. Doi: 10.1016/S0618-8278(19)30301-9 [Poster]
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** Remetic, J; Mlitz, V; Kunczer, V; Schargl, H; Stojakovic, T; Fuchs, C; Trauner, M Loss of bile salt export pump (Bsep/Abcb11) aggravates lipopolysaccharide induced hepatic inflammation in mice
J HEPATOL. 2019; 70: E169-E169. Doi: 10.1016/S0618-8278(19)30305-6 [Poster]
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** Tardelli, M; Bruschi, F; Claudel, T; Auer, N; Kunczer, V; Stojakovic, T; Herac, M; Lotersztajn, S; Trauner, M Monoacylglycerol lipase deletion protects against obesity-induced hepatic steatosis via PPARg regulation in adipose tissue and fatty acid malabsorption in the intestine
J HEPATOL. 2019; 70: E548-E548. Doi: 10.1016/S0618-8278(19)31087-4 [Poster]
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** Zhu, C; Boucheron, N; Muller, A; Majek, P; Fuchs, C; Baazim, H; Lercher, A; Halilbasic, E; Gulich, A; Sakaguchi, S; Sandner, L; Stojakovic, T; Scharnagl, H; Bergthaler, A; Ellmeier, W; Trauner, M 24-nor-ursodeoxycholic acid ameliorates inflammation by reshaping mTOR proteome and immunometabolism sensing programs in CD8 T cells
EUR J IMMUNOL. 2019; 49: 1282-1282.-17th International Congress of Immunology (IUIS); OCT 19-23, 2019; Beijing, PEOPLES R CHINA. [Poster]
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** Zhu, C; Boucheron, N; Muller, A; Majek, P; Fuchs, CD; Baazim, H; Halilbasic, E; Stojakovic, T; Bergthaler, A; Ellmeier, W; Trauner, M 24-nor-ursodeoxycholic acid ameliorates inflammation by reshaping mTOR proteome and immunometabolism sensing programs in CD8 T-cells
J HEPATOL. 2019; 70(1): E9-E10. Doi: 10.1016/S0618-8278(19)30016-7 [Poster]
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2018

Full paper/article (Journal)

** Beinhardt, S; Al-Zoairy, R; Kozbial, K; Stättermayer, AF; Maieron, A; Stauber, R; Strasser, M; Zoller, H; Graziadei, I; Rasoul-Rockenschaub, S; Trauner, M; Ferenci, P; Hofer, H Long-term follow-up of ribavirin-free DAA-based treatment in HCV recurrence after orthotopic liver transplantation.
Liver Int. 2018; 38(7):1188-1197 Doi: 10.1111/liv.13652 [OPEN ACCESS]
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** Fuchs, CD; Paumgartner, G; Mlitz, V; Kunczer, V; Halilbasic, E; Leditznig, N; Wahlström, A; Ståhlman, M; Thüringer, A; Kashofer, K; Stojakovic, T; Marschall, HU; Trauner, M Colesevelam attenuates cholestatic liver and bile duct injury in Mdr2^-/- mice by modulating composition, signalling and excretion of faecal bile acids.
Gut. 2018; 67(9):1683-1691 Doi: 10.1136/gutjnl-2017-314553 [OPEN ACCESS]
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** Peter, J; Fournier, C; Durdevic, M; Knoblich, L; Keip, B; Dejaco, C; Trauner, M; Moser, G A Microbial Signature of Psychological Distress in Irritable Bowel Syndrome.
Psychosom Med. 2018; 80(8):698-709 Doi: 10.1097/PSY.0000000000000630 [OPEN ACCESS]
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** Pollheimer, MJ; Racedo, S; Mikels-Vigdal, A; Marshall, D; Bowlus, C; Lackner, C; Madl, T; Karlsen, TH; Hov, JR; Lyman, SK; Adamkewicz, J; Smith, V; Moreau, E; Zollner, G; Eide, TJ; Stojakovic, T; Scharnagl, H; Gruber, HJ; Stauber, RE; Trauner, M; Fickert, P Lysyl oxidase-like protein 2 (LOXL2) modulates barrier function in cholangiocytes in cholestasis.
J Hepatol. 2018; 69(2):368-377 Doi: 10.1016/j.jhep.2018.04.009
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** Tang, Y; Blomenkamp, KS; Fickert, P; Trauner, M; Teckman, JH NorUDCA promotes degradation of α1-antitrypsin mutant Z protein by inducing autophagy through AMPK/ULK1 pathway.
PLoS One. 2018; 13(8):e0200897-e0200897 Doi: 10.1371/journal.pone.0200897 [OPEN ACCESS]
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Abstract (Journal)

** Fuchs, C; Paumgartner, G; Mlitz, V; Wolfrum, S; Wahlstrom, A; Stahlman, M; Stojakovic, T; Wolfrum, C; Marschall, HU; Trauner, M Loss of BSEP protects MDR2/ABCB4 KO mice from cholestatic liver injury by altering bile acid profile and signaling
J HEPATOL. 2018; 68: S449-S450. Doi: 10.1016/S0168-8278(18)31141-3
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** Kozbial, K; Al-Zoairy, R; Schaefer, B; Gschwantler, M; Stauber, RE; Hametner, S; Maieron, A; Laferl, H; Strasser, M; Hayat-Khayyati, A; Datz, C; Kramer, L; Graziadei, I; Stattermayer, A; Beinhardt, S; Munda, P; Zoller, H; Trauner, M; Hofer, H; Ferenci, P Real world experience of retreatment of chronic hepatitis C patients who failed IFN-free DAA therapy
J HEPATOL. 2018; 68: S279-S280.-International Liver Congress (ILC); APR 11-15, 2018; Paris, FRANCE. Doi: 10.1016/S0168-8278(18)30776-1 [Poster]
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** Pollheimer, M; Racedo, S; Mikels-Vigdal, A; Bowlus, C; Lackner, C; Karlsen, TH; Hov, JR; Lyman, SK; Adamkewicz, J; Smith, V; Moreau, E; Eide, TJ; Stojakovic, T; Stauber, RE; Trauner, M; Fickert, P Lysyl oxidase-like protein 2 in cholangiopathies
VIRCHOWS ARCH. 2018; 473: S6-S7.-30th European Congress of Pathology; 08-12.09, 2018 ; Bilbao. [Oral Communication]
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** Stauber, RE; Staufer, K; Stift, J; Marculescu, R; Obermayer-Pietsch, B; Trauner, M; Lackner, K Enhanced liver fibrosis (ELF) score accurately detects advanced fibrosis in nonalcoholic fatty liver disease (NAFLD)
J HEPATOL. 2018; 68: S563-S563.-International Liver Congress (ILC); APR 11-15, 2018; Paris, FRANCE. Doi: 10.1016/S0168-8278(18)31383-7 [Poster]
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2017

Full paper/article (Journal)

** Fickert, P; Hirschfield, GM; Denk, G; Marschall, HU; Altorjay, I; Färkkilä, M; Schramm, C; Spengler, U; Chapman, R; Bergquist, A; Schrumpf, E; Nevens, F; Trivedi, P; Reiter, FP; Tornai, I; Halilbasic, E; Greinwald, R; Pröls, M; Manns, MP; Trauner, M; European PSC norUDCA Study Group norUrsodeoxycholic acid improves cholestasis in primary sclerosing cholangitis.
J Hepatol. 2017; 67(3):549-558 Doi: 10.1016/j.jhep.2017.05.009 [OPEN ACCESS]
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** Fuchs, CD; Claudel, T; Scharnagl, H; Stojakovic, T; Trauner, M FXR controls CHOP expression in steatohepatitis.
FEBS Lett. 2017; 591(20):3360-3368 Doi: 10.1002/1873-3468.12845 [OPEN ACCESS]
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** Fuchs, CD; Paumgartner, G; Wahlström, A; Schwabl, P; Reiberger, T; Leditznig, N; Stojakovic, T; Rohr-Udilova, N; Chiba, P; Marschall, HU; Trauner, M Metabolic preconditioning protects BSEP/ABCB11^-/- mice against cholestatic liver injury.
J Hepatol. 2017; 66(1):95-101 Doi: 10.1016/j.jhep.2016.08.017 [OPEN ACCESS]
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** Horvatits, T; Drolz, A; Roedl, K; Rutter, K; Ferlitsch, A; Fauler, G; Trauner, M; Fuhrmann, V Serum bile acids as marker for acute decompensation and acute-on-chronic liver failure in patients with non-cholestatic cirrhosis.
Liver Int. 2017; 37(2):224-231 Doi: 10.1111/liv.13201
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** Horvatits, T; Drolz, A; Rutter, K; Roedl, K; Fauler, G; Müller, C; Kluge, S; Trauner, M; Schenk, P; Fuhrmann, V Serum bile acids in patients with hepatopulmonary syndrome.
Z GASTROENTEROL. 2017; 55(4): 361-367. Doi: 10.1055/s-0042-121268
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** Horvatits, T; Drolz, A; Rutter, K; Roedl, K; Langouche, L; Van den Berghe, G; Fauler, G; Meyer, B; Hülsmann, M; Heinz, G; Trauner, M; Fuhrmann, V Circulating bile acids predict outcome in critically ill patients.
ANN INTENSIVE CARE. 2017; 7(1): 48-48. Doi: 10.1186/s13613-017-0272-7 [OPEN ACCESS]
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** Krones, E; Eller, K; Pollheimer, MJ; Racedo, S; Kirsch, AH; Frauscher, B; Wahlström, A; Ståhlman, M; Trauner, M; Grahammer, F; Huber, TB; Wagner, K; Rosenkranz, AR; Marschall, HU; Fickert, P NorUrsodeoxycholic acid ameliorates cholemic nephropathy in bile duct ligated mice.
J Hepatol. 2017; 67(1):110-119 Doi: 10.1016/j.jhep.2017.02.019
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** Paternostro, R; Wagner, D; Reiberger, T; Mandorfer, M; Schwarzer, R; Ferlitsch, M; Trauner, M; Peck-Radosavljevic, M; Ferlitsch, A Low 25-OH-vitamin D levels reflect hepatic dysfunction and are associated with mortality in patients with liver cirrhosis.
Wien Klin Wochenschr. 2017; 129(1-2):8-15 Doi: 10.1007/s00508-016-1127-1 [OPEN ACCESS]
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Abstract (Journal)

** Dengler, M; Staufer, K; Huber, H; Stauber, R; Bantel, H; Weiss, KH; Starlinger, P; Pock, H; Kloters-Plachky, P; Gotthardt, DN; Rauch, P; Lackner, C; Stift, J; Brostjan, C; Gruenberger, T; Kumada, T; Toyoda, H; Tada, T; Weiss, TS; Trauner, M; Mikulits, W Soluble Axl identifies patients at higher risk for hepatocellular carcinoma development: results from a large scale multicenter analysis
J HEPATOL. 2017; 66(1):S626-S626.-International Liver Congress / 52nd Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 19-23, 2017; Amsterdam, NETHERLANDS. Doi: 10.1016/S0168-8278(17)31697-5 [Poster]
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** Fuchs, CD; Paumgartner, G; Halilbasic, E; Leditznig, N; Wahlstrom, A; Stahlman, M; Stojakovic, T; Marschall, HU; Trauner, M Colesevelam attenuates cholestatic liver and bile duct injury in Mdr2(-/-) mice by modulating fecal bile acid composition and signaling
J HEPATOL. .. 2017; 66(1):S364-S364.-International Liver Congress / 52nd Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 19-23, 2017; Amsterdam, NETHERLANDS. Doi: 10.1016/S0168-8278(17)31068-1 [Poster]
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** Moustafa, T; Zaufel, A; Eichmann, T; Kolb-Lenz, D; Trauner, M; Fickert, P Regulation of the mechanistic target of rapamycin complex 1 (mTORC1) - nuclear hormone receptor signaling by bile acids
J HEPATOL. 2017; 66(1):S111-S111.-International Liver Congress / 52nd Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 19-23, 2017; Amsterdam, NETHERLANDS. Doi: 10.1016/S0168-8278(17)30481-6 [Poster]
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** Steinacher, D; Claudel, T; Griessner, J; Einwallner, E; Ruhlemann, MC; Ronda, O; Heinsen, FA; Stojakovic, T; Scharnagl, H; Verkade, HJ; Haubensak, WE; Trauner, M NorUDCA improves liver injury and metabolic situation in mouse models of obesity and steatosis
J HEPATOL. 2017; 66(1):S168-S168.-International Liver Congress / 52nd Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 19-23, 2017; Amsterdam, NETHERLANDS. Doi: 10.1016/S0168-8278(17)30616-5 [Poster]
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Comment

** Lackner, C; Bataller, R; Burt, A; Miquel, R; Schuppan, D; Tiniakos, D; Trauner, M Fibrosis evaluation by transient elastography in alcoholic liver disease: Is the histological scoring system impacting cutoff values?
Hepatology. 2017; 65(5):1758-1761 Doi: 10.1002/hep.29075 [OPEN ACCESS]
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Guideline

** Reiberger, T; Püspök, A; Schoder, M; Baumann-Durchschein, F; Bucsics, T; Datz, C; Dolak, W; Ferlitsch, A; Finkenstedt, A; Graziadei, I; Hametner, S; Karnel, F; Krones, E; Maieron, A; Mandorfer, M; Peck-Radosavljevic, M; Rainer, F; Schwabl, P; Stadlbauer, V; Stauber, R; Tilg, H; Trauner, M; Zoller, H; Schöfl, R; Fickert, P Austrian consensus guidelines on the management and treatment of portal hypertension (Billroth III).
Wien Klin Wochenschr. 2017; 129(Suppl 3):135-158 Doi: 10.1007/s00508-017-1262-3 [OPEN ACCESS]
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2016

Full paper/article (Journal)

** Baghdasaryan, A; Fuchs, CD; Österreicher, CH; Lemberger, UJ; Halilbasic, E; Påhlman, I; Graffner, H; Krones, E; Fickert, P; Wahlström, A; Ståhlman, M; Paumgartner, G; Marschall, HU; Trauner, M Inhibition of intestinal bile acid absorption improves cholestatic liver and bile duct injury in a mouse model of sclerosing cholangitis.
J Hepatol. 2016; 64(3):674-681 Doi: 10.1016/j.jhep.2015.10.024 [OPEN ACCESS]
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** Beinhardt, S; Al Zoairy, R; Ferenci, P; Kozbial, K; Freissmuth, C; Stern, R; Stättermayer, AF; Stauber, R; Strasser, M; Zoller, H; Watschinger, B; Schmidt, A; Trauner, M; Hofer, H; Maieron, A DAA-based antiviral treatment of patients with chronic hepatitis C in the pre- and postkidney transplantation setting.
Transpl Int. 2016; 29(9):999-1007 Doi: 10.1111/tri.12799 [OPEN ACCESS]
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** Graziadei, I; Zoller, H; Fickert, P; Schneeberger, S; Finkenstedt, A; Peck-Radosavljevic, M; Müller, H; Kohl, C; Sperner-Unterweger, B; Eschertzhuber, S; Hofer, H; Öfner, D; Tilg, H; Vogel, W; Trauner, M; Berlakovich, G Indications for liver transplantation in adults : Recommendations of the Austrian Society for Gastroenterology and Hepatology (ÖGGH) in cooperation with the Austrian Society for Transplantation, Transfusion and Genetics (ATX).
Wien Klin Wochenschr. 2016; 128(19-20):679-690 Doi: 10.1007/s00508-016-1046-1 [OPEN ACCESS]
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** Hörl, G; Froehlich, H; Ferstl, U; Ledinski, G; Binder, J; Cvirn, G; Stojakovic, T; Trauner, M; Koidl, C; Tafeit, E; Amrein, K; Scharnagl, H; Jürgens, G; Hallström, S Simvastatin Efficiently Lowers Small LDL-IgG Immune Complex Levels: A Therapeutic Quality beyond the Lipid-Lowering Effect.
PLoS One. 2016; 11(2):e0148210-e0148210 Doi: 10.1371/journal.pone.0148210 [OPEN ACCESS]
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** Lemberger, UJ; Fuchs, CD; Karer, M; Haas, S; Stojakovic, T; Schöfer, C; Marschall, HU; Wrba, F; Taketo, MM; Egger, G; Trauner, M; Österreicher, CH Hepatocyte specific expression of an oncogenic variant of β-catenin results in cholestatic liver disease.
Oncotarget. 2016; 7(52):86985-86998 Doi: 10.18632/oncotarget.13521 [OPEN ACCESS]
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** Reiter, FP; Wimmer, R; Wottke, L; Artmann, R; Nagel, JM; Carranza, MO; Mayr, D; Rust, C; Fickert, P; Trauner, M; Gerbes, AL; Hohenester, S; Denk, GU Role of interleukin-1 and its antagonism of hepatic stellate cell proliferation and liver fibrosis in the Abcb4(-/-) mouse model.
World J Hepatol. 2016; 8(8):401-410 Doi: 10.4254/wjh.v8.i8.401 [OPEN ACCESS]
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** Tang, Y; Fickert, P; Trauner, M; Marcus, N; Blomenkamp, K; Teckman, J Autophagy induced by exogenous bile acids is therapeutic in a model of α-1-AT deficiency liver disease.
Am J Physiol Gastrointest Liver Physiol. 2016; 311(1):G156-G165 Doi: 10.1152/ajpgi.00143.2015 [OPEN ACCESS]
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Short report/Letter

** Kozbial, K; Moser, S; Schwarzer, R; Laferl, H; Al-Zoairy, R; Stauber, R; Stättermayer, AF; Beinhardt, S; Graziadei, I; Freissmuth, C; Maieron, A; Gschwantler, M; Strasser, M; Peck-Radosalvjevic, M; Trauner, M; Hofer, H; Ferenci, P Unexpected high incidence of hepatocellular carcinoma in cirrhotic patients with sustained virologic response following interferon-free direct-acting antiviral treatment.
J Hepatol. 2016; 65(4):856-858 Doi: 10.1016/j.jhep.2016.06.009 [OPEN ACCESS]
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Review

** Wagner, M; Trauner, M Recent advances in understanding and managing cholestasis.
F1000Res. 2016; 5(8): Doi: 10.12688/f1000research.8012.1 [OPEN ACCESS]
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Abstract (Journal)

** Beinhardt, S; Al-Zoairy, R; Freissmuth, C; Kozbial, K; Stern, R; Stattermayer, AF; Zoller, H; Maieron, A; Stauber, R; Staufer, K; Strasser, M; Vogel, W; Peck-Radosaljevic, M; Trauner, M; Ferenci, P; Hofer, H; SAFETY AND EFFICACY OF IFNANDRBV-FREE DAA-BASED REGIMENS IN HCV-RECURRENCE AFTER ORTHOTOPIC LIVER TRANSPLANTATION.
J HEPATOL. 2016; 64: S818-S818. Doi: 10.1016/S0168-8278(16)01599-3 [Poster]
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** Horvatits, T; Drolz, A; Roedl, K; Horvatits, K; Ferlitsch, A; Fauler, G; Trauner, M; Fuhrmann, V Bile acids as marker for acute decompensation and ACLF in patients with liver cirrhosis
MED KLIN-INTENSIVMED. 2016; 111(4):381-381. [Poster]
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** Lemberger, U; Fuchs, C; Karer, M; Stojakovic, T; Meier, S; Schofer, C; Egger, G; Wrba, F; Gerner, C; Taketo, M; Trauner, M; Oesterreicher, CH; HEPATOCYTE SPECIFIC EXPRESSION OF A DOMINANT STABLE FORM OF B-CATENIN RESULTS IN EARLY LETHALITY DUE TO DISTURBANCES IN LIPID AND GLUCOSE METABOLISM.
J HEPATOL. JOURNAL OF HEPATOLOGY64: S687-S687. AMSTERDAM: ELSEVIER SCIENCE BV; ( Presented at: EASL International Liver Congress, Barcelona, SPAIN, APR 13-17, 2016) Doi: 10.1016/S0168-8278(16)01309-X
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** Trauner, M; Fickert, P; Hirschfield, G; Reiter, F; Altorjay, I; Marschall, U; Farkkila, M; Schramm, C; Spengler, U; Chapman, R; Bergquist, A; Schrumpf, E; Nevens, F; Halilbasic, E; Greinwald, R; Proels, M; Manns, MP; NORURSODEOXYCHOLIC ACID IMPROVES CHOLESTASIS IN PRIMARY SCLEROSING CHOLANGITIS: RESULTS OF A PHASE II DOSE FINDING STUDY.
J HEPATOL. 2016; 64: S208-S209.-EASL International Liver Congress; APR 13-17, 2016; Barcelona, SPAIN. Doi: 10.1016/S0168-8278(16)00171-9 [Oral Communication]
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Comment

** Krones, E; Erwa, W; Trauner, M; Fickert, P Reply.
Hepatology. 2016; 63(1):346-347 Doi: 10.1002/hep.27873 [OPEN ACCESS]
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2015

Full paper/article (Journal)

** Bitter, A; Rümmele, P; Klein, K; Kandel, BA; Rieger, JK; Nüssler, AK; Zanger, UM; Trauner, M; Schwab, M; Burk, O Pregnane X receptor activation and silencing promote steatosis of human hepatic cells by distinct lipogenic mechanisms.
Arch Toxicol. 2015; 89(11):2089-2103 Doi: 10.1007/s00204-014-1348-x
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** Chmelík, M; Valkovič, L; Wolf, P; Bogner, W; Gajdošík, M; Halilbasic, E; Gruber, S; Trauner, M; Krebs, M; Trattnig, S; Krššák, M Phosphatidylcholine contributes to in vivo (31)P MRS signal from the human liver.
Eur Radiol. 2015; 25(7):2059-2066 Doi: 10.1007/s00330-014-3578-y
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** Hartig, SM; Bader, DA; Abadie, KV; Motamed, M; Hamilton, MP; Long, W; York, B; Mueller, M; Wagner, M; Trauner, M; Chan, L; Bajaj, M; Moore, DD; Mancini, MA; McGuire, SE Ubc9 Impairs Activation of the Brown Fat Energy Metabolism Program in Human White Adipocytes.
Mol Endocrinol. 2015; 29(9):1320-1333 Doi: 10.1210/me.2015-1084 [OPEN ACCESS]
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** Hirschfield, GM; Mason, A; Luketic, V; Lindor, K; Gordon, SC; Mayo, M; Kowdley, KV; Vincent, C; Bodhenheimer, HC; Parés, A; Trauner, M; Marschall, HU; Adorini, L; Sciacca, C; Beecher-Jones, T; Castelloe, E; Böhm, O; Shapiro, D Efficacy of obeticholic acid in patients with primary biliary cirrhosis and inadequate response to ursodeoxycholic acid.
Gastroenterology. 2015; 148(4):751-761 Doi: 10.1053/j.gastro.2014.12.005 [OPEN ACCESS]
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** Jahnel, J; Zöhrer, E; Alisi, A; Ferrari, F; Ceccarelli, S; De Vito, R; Scharnagl, H; Stojakovic, T; Fauler, G; Trauner, M; Nobili, V Serum Bile Acid Levels in Children With Nonalcoholic Fatty Liver Disease.
J Pediatr Gastroenterol Nutr. 2015; 61(1):85-90 Doi: 10.1097/MPG.0000000000000774
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** Jeschek, P; Ferlitsch, A; Salzl, P; Heinze, G; Györi, G; Reinhart, K; Waldmann, E; Britto-Arias, M; Trauner, M; Ferlitsch, M A greater proportion of liver transplant candidates have colorectal neoplasia than in the healthy screening population.
Clin Gastroenterol Hepatol. 2015; 13(5):956-962 Doi: 10.1016/j.cgh.2014.08.018
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** Kozbial, K; Reinhart, K; Heinze, G; Zwatz, C; Bannert, C; Salzl, P; Waldmann, E; Britto-Arias, M; Ferlitsch, A; Trauner, M; Weiss, W; Ferlitsch, M High quality of screening colonoscopy in Austria is not dependent on endoscopist specialty or setting.
Endoscopy. 2015; 47(3):207-216 Doi: 10.1055/s-0034-1390910
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** Mandorfer, M; Payer, BA; Schwabl, P; Steiner, S; Ferlitsch, A; Aichelburg, MC; Stättermayer, AF; Ferenci, P; Obermayer-Pietsch, B; Grabmeier-Pfistershammer, K; Trauner, M; Peck-Radosavljevic, M; Reiberger, T Revisiting liver disease progression in HIV/HCV-coinfected patients: the influence of vitamin D, insulin resistance, immune status, IL28B and PNPLA3.
Liver Int. 2015; 35(3):876-885 Doi: 10.1111/liv.12615
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** Mandorfer, M; Steiner, S; Schwabl, P; Payer, BA; Aichelburg, MC; Lang, G; Grabmeier-Pfistershammer, K; Trauner, M; Peck-Radosavljevic, M; Reiberger, T Response-guided boceprevir-based triple therapy in HIV/HCV-coinfected patients: the HIVCOBOC-RGT study.
J Infect Dis. 2015; 211(5):729-735 Doi: 10.1093/infdis/jiu516 [OPEN ACCESS]
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** Mueller, M; Thorell, A; Claudel, T; Jha, P; Koefeler, H; Lackner, C; Hoesel, B; Fauler, G; Stojakovic, T; Einarsson, C; Marschall, HU; Trauner, M Ursodeoxycholic acid exerts farnesoid X receptor-antagonistic effects on bile acid and lipid metabolism in morbid obesity.
J Hepatol. 2015; 62(6):1398-1404 Doi: 10.1016/j.jhep.2014.12.034 [OPEN ACCESS]
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** Reichl, P; Fang, M; Starlinger, P; Staufer, K; Nenutil, R; Muller, P; Greplova, K; Valik, D; Dooley, S; Brostjan, C; Gruenberger, T; Shen, J; Man, K; Trauner, M; Yu, J; Gao, CF; Mikulits, W Multicenter analysis of soluble Axl reveals diagnostic value for very early stage hepatocellular carcinoma.
Int J Cancer. 2015; 137(2):385-394 Doi: 10.1002/ijc.29394 [OPEN ACCESS]
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** Rutter, K; Stättermayer, AF; Beinhardt, S; Scherzer, TM; Steindl-Munda, P; Trauner, M; Ferenci, P; Hofer, H Successful anti-viral treatment improves survival of patients with advanced liver disease due to chronic hepatitis C.
Aliment Pharmacol Ther. 2015; 41(6):521-531 Doi: 10.1111/apt.13085 [OPEN ACCESS]
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** Schwabl, P; Bota, S; Salzl, P; Mandorfer, M; Payer, BA; Ferlitsch, A; Stift, J; Wrba, F; Trauner, M; Peck-Radosavljevic, M; Reiberger, T New reliability criteria for transient elastography increase the number of accurate measurements for screening of cirrhosis and portal hypertension.
Liver Int. 2015; 35(2):381-390 Doi: 10.1111/liv.12623
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** Schwabl, P; Bucsics, T; Soucek, K; Mandorfer, M; Bota, S; Blacky, A; Hirschl, AM; Ferlitsch, A; Trauner, M; Peck-Radosavljevic, M; Reiberger, T Risk factors for development of spontaneous bacterial peritonitis and subsequent mortality in cirrhotic patients with ascites.
Liver Int. 2015; 35(9):2121-2128 Doi: 10.1111/liv.12795
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** Sombetzki, M; Fuchs, CD; Fickert, P; Österreicher, CH; Mueller, M; Claudel, T; Loebermann, M; Engelmann, R; Langner, C; Sahin, E; Schwinge, D; Guenther, ND; Schramm, C; Mueller-Hilke, B; Reisinger, EC; Trauner, M 24-nor-ursodeoxycholic acid ameliorates inflammatory response and liver fibrosis in a murine model of hepatic schistosomiasis.
J Hepatol. 2015; 62(4):871-878 Doi: 10.1016/j.jhep.2014.11.020 [OPEN ACCESS]
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** Stättermayer, AF; Traussnigg, S; Dienes, HP; Aigner, E; Stauber, R; Lackner, K; Hofer, H; Stift, J; Wrba, F; Stadlmayr, A; Datz, C; Strasser, M; Maieron, A; Trauner, M; Ferenci, P Hepatic steatosis in Wilson disease--Role of copper and PNPLA3 mutations.
J Hepatol. 2015; 63(1):156-163 Doi: 10.1016/j.jhep.2015.01.034
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** Stiedl, P; McMahon, R; Blaas, L; Stanek, V; Svinka, J; Grabner, B; Zollner, G; Kessler, SM; Claudel, T; Müller, M; Mikulits, W; Bilban, M; Esterbauer, H; Eferl, R; Haybaeck, J; Trauner, M; Casanova, E Growth hormone resistance exacerbates cholestasis-induced murine liver fibrosis.
Hepatology. 2015; 61(2):613-626 Doi: 10.1002/hep.27408 [OPEN ACCESS]
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** Waldmann, E; Britto-Arias, M; Gessl, I; Heinze, G; Salzl, P; Sallinger, D; Trauner, M; Weiss, W; Ferlitsch, A; Ferlitsch, M Endoscopists with low adenoma detection rates benefit from high-definition endoscopy.
Surg Endosc. 2015; 29(2):466-473 Doi: 10.1007/s00464-014-3688-2
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Short report/Letter

** Krones, E; Erwa, W; Trauner, M; Fickert, P Serum alkaline phosphatase levels accurately reflect cholestasis in mice.
Hepatology. 2015; 62(3):981-983 Doi: 10.1002/hep.27622 [OPEN ACCESS]
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Review

** Krones, E; Wagner, M; Eller, K; Rosenkranz, AR; Trauner, M; Fickert, P Bile acid-induced cholemic nephropathy.
Dig Dis. 2015; 33(3):367-375 Doi: 10.1159/000371689
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** Trauner, M; Halilbasic, E; Claudel, T; Steinacher, D; Fuchs, C; Moustafa, T; Pollheimer, M; Krones, E; Kienbacher, C; Traussnigg, S; Kazemi-Shirazi, L; Munda, P; Hofer, H; Fickert, P; Paumgartner, G Potential of nor-Ursodeoxycholic Acid in Cholestatic and Metabolic Disorders.
Dig Dis. 2015; 33(3):433-439 Doi: 10.1159/000371904
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Abstract (Journal)

** Beinhardt, S; Al Zoairy, R; Freissmuth, C; Kozbial, K; Hametner, S; Stern, R; Stauber, RE; Maieron, A; Staufer, K; Strasser, MP; Zoller, HM; Graziadei, I; Vogel, W; Peck-Radosavljevic, M; Trauner, M; Ferenci, P; Hofer, H Efficacy and safety of IFN-free, DAA-based treatment-regimens in patients with HCV-recurrence after Liver Transplantation: Real-life experience from Austria
HEPATOLOGY. . 2015; 62: 746A-747A.-66th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD); NOV 13-17, 2015; San Francisco, CA. [Oral Communication]
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** Beinhardt, S; Freissmuth, C; Al-Zoairy, R; Kozbial, K; Hametner, S; Stern, R; Stauber, R; Maieron, A; Staufer, K; Strasser, M; Zoller, H; Graziadei, I; Vogel, W; Peck-Radosavljevic, M; Trauner, M; Ferenci, P; Hofer, H EFFICACY AND SAFETY OF IFN-FREE ANTIVIRAL THERAPY IN PATIENTS WITH HCV RECURRENCE AFTER LIVER TRANSPLANTATION: REAL-LIFE EXPERIENCE FROM AUSTRIA
J HEPATOL. 2015; 62: S282-S283.-50th International Liver Congress of the European-Association-for-the-Study-of-the-Liver; APR 22-26, 2015; Vienna, AUSTRIA. Doi: 10.1016/S0168-8278(15)30192-6 [Poster]
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** Beinhardt, S; Kozbial, K; Schmidt, A; Freissmuth, C; Mandorfer, M; Strassl, R; al Zoairy, R; Stauber, R; Strasser, M; Sunder-Plassmann, G; Trauner, M; Peck-Radosavljevic, M; Vogel, W; Hofer, H; Ferenci, P REAL LIFE EXPERIENCE WITH INTERFERON/RIBAVIRIN-FREE ANTIVIRAL TREATMENT IN RENAL TRANSPLANT RECIPIENTS AND ENDSTAGE RENAL DISEASE-PATIENTS ON DIALYSIS INFECTED WITH HEPATITIS C VIRUS
J HEPATOL. 2015; 62: S667-S667.-50th International Liver Congress of the European-Association-for-the-Study-of-the-Liver; APR 22-26, 2015; Vienna, AUSTRIA. Doi: 10.1016/S0168-8278(15)31073-4 [Poster]
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** Fuchs, CD; Claudel, T; Halilbasic, E; Jha, P; Spindelboeck, W; Stojakovic, T; Trauner, M ROLE OF FXR CONTROLLED Chop IN MEDIATING BILE ACID EFFECTS IN NAFLD.
J HEPATOL. 2015; 62(S2):S689-S689.-50th Annual Meeting of the European Association for the Study of the Liver (EASL); APR 22-26, 2015; Vienna, AUSTRIA. [Poster]
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** Kienbacher, C; Dolak, W; Traussnigg, S; Steindl-Munda, P; Oettl, K; Stadlbauer, V; Knapp, S; Vogelsang, H; Trauner, M METABOLIC DISTURBANCES AFTER FRUCTOSE OVERCONSUMPTION ARE NOT LINKED TO INTESTINAL PERMEABILITY IN HEALTHY YOUNG VOLUNTEERS
J HEPATOL. 2015; 62: S719-S719.-50th International Liver Congress of the European-Association-for-the-Study-of-the-Liver; APR 22-26, 2015; Vienna, AUSTRIA. Doi: 10.1016/S0168-8278(15)31193-4 [Poster]
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** Lemberger, UJ; Fuchs, C; Karer, M; Schöfer, C; Stojakovic, T; Wrba, F; Taketo, MM; Trauner, M; Österreicher, CH HEPATOCYTE SPECIFIC EXPRESSION OF A DOMINANT STABLE FORM OF BETA-CATENIN RESULTS IN CHOLESTATIC LIVER DISEASE.
J HEPATOL. 2015; 62(S2):S781-S781.-50th Annual Meeting of the European Association for the Study of the Liver (EASL); APR 22-26, 2015; Vienna, AUSTRIA. Doi: 10.1016/S0168-8278(15)31341-6 [Poster]
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** Panzitt, K; Marschall, HU; Trauner, M; Fickert, P; Wagner, M Effects of Ursodeoxycholic-acid and Rifampicin on autophagy in the liver
HEPATOLOGY. . 2015; 62: 538A-538A.-66th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD); NOV 13-17, 2015; San Francisco, CA. [Oral Communication]
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** Staufer, K; Stauber, R; Theek, C; von Darl, M; Traussnigg, S; Kienbacher, C; Lackner, C; Steindl-Munda, P; Schulz-Knappe, P; Trauner, M MINIMALLY INVASIVE DIAGNOSIS OF NAFLD AND DISCRIMINATION BETWEEN NAFL AND NASH BY AUTOANTIBODY SIGNATURES
J HEPATOL. 2015; 62: S746-S746.-50th International Liver Congress of the European-Association-for-the-Study-of-the-Liver; APR 22-26, 2015; Vienna, AUSTRIA. Doi: 10.1016/S0168-8278(15)31258-7 [Poster]
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** Steinacher, D; Claudel, T; Stojakovic, T; Trauner, M NorUDCA-Therapy leads to reduced Inflammation in Fat Tissue and the Liver, and improves Glucose-Tolerance in Ob/Ob Mouse Model of Obesity and Fatty Liver.
WIEN KLIN WOCHENSCHR. 2015; 127(17-18):738-738.-16. Jahrestagung der Österreichischen Adipositas Gesellschaft (ÖAG); OCT 23-24, 2015; Vienna, AUSTRIA. [Oral Communication]
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** Steinacher, D; Claudel, T; Stojakovic, T; Trauner, M NorUDCA reduces liver injury and improves glucose sensitivity in a mouse model of obesity and steatosis.
HEPATOLOGY. . 2015; 62: 689A-689A.-66th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD); NOV 13-17, 2015; San Francisco, CA. [Oral Communication]
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** Stiedl, P; McMahon, R; Blaas, L; Stanek, V; Svinka, J; Grabner, B; Zollner, G; Kressler, S; Claudel, T; Muller, M; Mikulits, W; Esterbauer, H; Eferl, R; Haybaeck, J; Trauner, M; Casanova, E THE ROLE OF GROWTH HORMONE RECEPTOR IN LIVER FIBROSIS AND CANCER
J HEPATOL. 2015; 62: S792-S792.-50th International Liver Congress of the European-Association-for-the-Study-of-the-Liver; APR 22-26, 2015; Vienna, AUSTRIA. Doi: 10.1016/S0168-8278(15)31366-0 [Poster]
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** Zöhrer, E; Jahnel, J; Fauler, G; Scharnagl, H; Stojakovic, T; Trauner, M; Nobili, V NONALCOHOLIC FATTY LIVER DISEASE: SERUM BILE ACID LEVELS IN CHILDREN AND ADOLESCENTS AS MARKER FOR PROGRESSION?
J HEPATOL. 2015; 62(S2):S717-S717.-50th Annual Meeting of the European Association for the Study of the Liver (EASL); APR 22-26, 2015; Vienna, AUSTRIA. [Poster]
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Comment

** Rupp, C; Stiehl, A; Trauner, M; Gotthardt, DN Editorial: further evidence for the role of serum alkaline phosphatase as a useful surrogate marker of prognosis in PSC - authors' reply.
Aliment Pharmacol Ther. 2015; 41(1): 151-152. Doi: 10.1111/apt.13020 [OPEN ACCESS]
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2014

Full paper/article (Journal)

** Aigner, E; Stadlmayr, A; Huber-Schönauer, U; Zwerina, J; Husar-Memmer, E; Niederseer, D; Trauner, M; Heuberger, A; Hohla, F; Schett, G; Patsch, W; Datz, C Gender- and site-specific differences of colorectal neoplasia relate to vitamin D.
Aliment Pharmacol Ther. 2014; 40(11-12):1341-1348 Doi: 10.1111/apt.12981 [OPEN ACCESS]
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** Bastati, N; Feier, D; Wibmer, A; Traussnigg, S; Balassy, C; Tamandl, D; Einspieler, H; Wrba, F; Trauner, M; Herold, C; Ba-Ssalamah, A Noninvasive differentiation of simple steatosis and steatohepatitis by using gadoxetic acid-enhanced MR imaging in patients with nonalcoholic fatty liver disease: a proof-of-concept study.
Radiology. 2014; 271(3): 739-747. Doi: 10.1148/radiol.14131890 [OPEN ACCESS]
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** Beinhardt, S; Leiss, W; Stättermayer, AF; Graziadei, I; Zoller, H; Stauber, R; Maieron, A; Datz, C; Steindl-Munda, P; Hofer, H; Vogel, W; Trauner, M; Ferenci, P Long-term outcomes of patients with Wilson disease in a large Austrian cohort.
Clin Gastroenterol Hepatol. 2014; 12(4):683-689 Doi: 10.1016/j.cgh.2013.09.025
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** Demetz, E; Schroll, A; Auer, K; Heim, C; Patsch, JR; Eller, P; Theurl, M; Theurl, I; Theurl, M; Seifert, M; Lener, D; Stanzl, U; Haschka, D; Asshoff, M; Dichtl, S; Nairz, M; Huber, E; Stadlinger, M; Moschen, AR; Li, X; Pallweber, P; Scharnagl, H; Stojakovic, T; März, W; Kleber, ME; Garlaschelli, K; Uboldi, P; Catapano, AL; Stellaard, F; Rudling, M; Kuba, K; Imai, Y; Arita, M; Schuetz, JD; Pramstaller, PP; Tietge, UJF; Trauner, M; Norata, GD; Claudel, T; Hicks, AA; Weiss, G; Tancevski, I The arachidonic acid metabolome serves as a conserved regulator of cholesterol metabolism.
Cell Metab. 2014; 20(5):787-798 Doi: 10.1016/j.cmet.2014.09.004 [OPEN ACCESS]
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** Dolak, W; Schreiber, F; Schwaighofer, H; Gschwantler, M; Plieschnegger, W; Ziachehabi, A; Mayer, A; Kramer, L; Kopecky, A; Schrutka-Kölbl, C; Wolkersdörfer, G; Madl, C; Berr, F; Trauner, M; Püspök, A, , Austrian, Biliary, RFA, Study, Group Endoscopic radiofrequency ablation for malignant biliary obstruction: a nationwide retrospective study of 84 consecutive applications.
Surg Endosc. 2014; 28(3):854-60 Doi: 10.1007/s00464-013-3232-9
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** Drolz, A; Horvatits, T; Michl, B; Roedl, K; Schellongowski, P; Holzinger, U; Zauner, C; Heinz, G; Madl, C; Trauner, M; Fuhrmann, V Statin therapy is associated with reduced incidence of hypoxic hepatitis in critically ill patients.
J Hepatol. 2014; 60(6):1187-1193 Doi: 10.1016/j.jhep.2014.01.019
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** Drolz, A; Wewalka, M; Horvatits, T; Fuhrmann, V; Schneeweiss, B; Trauner, M; Zauner, C Gender-specific differences in energy metabolism during the initial phase of critical illness.
Eur J Clin Nutr. 2014; 68(6):707-711 Doi: 10.1038/ejcn.2013.287
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** Ferlitsch, M; Heinze, G; Salzl, P; Britto-Arias, M; Waldmann, E; Reinhart, K; Bannert, C; Fasching, E; Knoflach, P; Weiss, W; Trauner, M; Ferlitsch, A Sex is a stronger predictor of colorectal adenoma and advanced adenoma than fecal occult blood test.
Med Oncol. 2014; 31(9):151-151 Doi: 10.1007/s12032-014-0151-0
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** García-Rodríguez, JL; Barbier-Torres, L; Fernández-Álvarez, S; Gutiérrez-de Juan, V; Monte, MJ; Halilbasic, E; Herranz, D; Álvarez, L; Aspichueta, P; Marín, JJ; Trauner, M; Mato, JM; Serrano, M; Beraza, N; Martínez-Chantar, ML SIRT1 controls liver regeneration by regulating bile acid metabolism through farnesoid X receptor and mammalian target of rapamycin signaling.
Hepatology. 2014; 59(5):1972-1983 Doi: 10.1002/hep.26971 [OPEN ACCESS]
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** Horvatits, T; Drolz, A; Roedl, K; Herkner, H; Ferlitsch, A; Perkmann, T; Müller, C; Trauner, M; Schenk, P; Fuhrmann, V Von Willebrand factor antigen for detection of hepatopulmonary syndrome in patients with cirrhosis.
J Hepatol. 2014; 61(3):544-549 Doi: 10.1016/j.jhep.2014.04.025
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** Hucke, F; Pinter, M; Graziadei, I; Bota, S; Vogel, W; Müller, C; Heinzl, H; Waneck, F; Trauner, M; Peck-Radosavljevic, M; Sieghart, W How to STATE suitability and START transarterial chemoembolization in patients with intermediate stage hepatocellular carcinoma.
J Hepatol. 2014; 61(6):1287-1296 Doi: 10.1016/j.jhep.2014.07.002
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** Hucke, F; Sieghart, W; Pinter, M; Graziadei, I; Vogel, W; Müller, C; Heinzl, H; Waneck, F; Trauner, M; Peck-Radosavljevic, M The ART-strategy: sequential assessment of the ART score predicts outcome of patients with hepatocellular carcinoma re-treated with TACE.
J Hepatol. 2014; 60(1):118-126 Doi: 10.1016/j.jhep.2013.08.022
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** Jahnel, J; Fickert, P; Hauer, AC; Högenauer, C; Avian, A; Trauner, M Inflammatory bowel disease alters intestinal bile acid transporter expression.
Drug Metab Dispos. 2014; 42(9):1423-1431 Doi: 10.1124/dmd.114.058065 [OPEN ACCESS]
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** Jha, P; Claudel, T; Baghdasaryan, A; Mueller, M; Halilbasic, E; Das, SK; Lass, A; Zimmermann, R; Zechner, R; Hoefler, G; Trauner, M Role of adipose triglyceride lipase (PNPLA2) in protection from hepatic inflammation in mouse models of steatohepatitis and endotoxemia.
Hepatology. 2014; 59(3):858-869 Doi: 10.1002/hep.26732 [OPEN ACCESS]
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** Jha, P; Knopf, A; Koefeler, H; Mueller, M; Lackner, C; Hoefler, G; Claudel, T; Trauner, M; Role of adipose tissue in methionine-choline-deficient model of non-alcoholic steatohepatitis (NASH).
BBA-MOL BASIS DIS. 2014; 1842(7): 959-970. Doi: 10.1016/j.bbadis.2014.02.012 [OPEN ACCESS]
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** Lanaya, H; Natarajan, A; Komposch, K; Li, L; Amberg, N; Chen, L; Wculek, SK; Hammer, M; Zenz, R; Peck-Radosavljevic, M; Sieghart, W; Trauner, M; Wang, H; Sibilia, M EGFR has a tumour-promoting role in liver macrophages during hepatocellular carcinoma formation.
Nat Cell Biol. 2014; 16(10): 1- 7. Doi: 10.1038/ncb3031 [OPEN ACCESS]
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** Maieron, A; Salzl, P; Peck-Radosavljevic, M; Trauner, M; Hametner, S; Schöfl, R; Ferenci, P; Ferlitsch, M Von Willebrand Factor as a new marker for non-invasive assessment of liver fibrosis and cirrhosis in patients with chronic hepatitis C.
Aliment Pharmacol Ther. 2014; 39(3):331-338 Doi: 10.1111/apt.12564 [OPEN ACCESS]
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** Mandorfer, M; Bota, S; Schwabl, P; Bucsics, T; Pfisterer, N; Kruzik, M; Hagmann, M; Blacky, A; Ferlitsch, A; Sieghart, W; Trauner, M; Peck-Radosavljevic, M; Reiberger, T Nonselective β blockers increase risk for hepatorenal syndrome and death in patients with cirrhosis and spontaneous bacterial peritonitis.
Gastroenterology. 2014; 146(7): 1680-1690. Doi: 10.1053/j.gastro.2014.03.005
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** Mandorfer, M; Bota, S; Schwabl, P; Bucsics, T; Pfisterer, N; Summereder, C; Hagmann, M; Blacky, A; Ferlitsch, A; Sieghart, W; Trauner, M; Peck-Radosavljevic, M; Reiberger, T Proton pump inhibitor intake neither predisposes to spontaneous bacterial peritonitis or other infections nor increases mortality in patients with cirrhosis and ascites.
PLoS One. 2014; 9(11):e110503-e110503 Doi: 10.1371/journal.pone.0110503 [OPEN ACCESS]
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** Mandorfer, M; Neukam, K; Rivero, A; Puoti, M; Boesecke, C; Baumgarten, A; Grzeszczuk, A; Zangerle, R; Ernst, D; Rockstroh, JK; Trauner, M; Pineda, JA; Peck-Radosavljevic, M; Reiberger, T Strategies for assignment of HIV-HCV genotype-1-coinfected patients to either dual-therapy or direct-acting antiviral agent-based triple-therapy.
Antivir Ther. 2014; 19(4):407-414 Doi: 10.3851/IMP2717
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** Mandorfer, M; Payer, BA; Niederecker, A; Lang, G; Aichelburg, MC; Strassl, R; Boesecke, C; Rieger, A; Trauner, M; Peck-Radosavljevic, M; Reiberger, T Therapeutic potential of and treatment with boceprevir/telaprevir-based triple-therapy in HIV/chronic hepatitis C co-infected patients in a real-world setting.
AIDS Patient Care STDS. 2014; 28(5): 221-227. Doi: 10.1089/apc.2013.0359
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** Mandorfer, M; Payer, BA; Scheiner, B; Breitenecker, F; Aichelburg, MC; Grabmeier-Pfistershammer, K; Rieger, A; Trauner, M; Peck-Radosavljevic, M; Reiberger, T Health-related quality of life and severity of fatigue in HIV/HCV co-infected patients before, during, and after antiviral therapy with pegylated interferon plus ribavirin.
Liver Int. 2014; 34(1): 69-77. Doi: 10.1111/liv.12253
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** Mandorfer, M; Reiberger, T; Payer, BA; Breitenecker, F; Aichelburg, MC; Obermayer-Pietsch, B; Rieger, A; Puoti, M; Zangerle, R; Trauner, M; Peck-Radosavljevic, M Revisiting predictors of virologic response to PEGIFN + RBV therapy in HIV-/HCV-coinfected patients: the role of metabolic factors and elevated GGT levels.
J Viral Hepat. 2014; 21(1):33-41 Doi: 10.1111/jvh.12118
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** Pandey, V; Sultan, M; Kashofer, K; Ralser, M; Amstislavskiy, V; Starmann, J; Osprian, I; Grimm, C; Hache, H; Yaspo, ML; Sültmann, H; Trauner, M; Denk, H; Zatloukal, K; Lehrach, H; Wierling, C Comparative analysis and modeling of the severity of steatohepatitis in DDC-treated mouse strains.
PLoS One. 2014; 9(10):e111006-e111006 Doi: 10.1371/journal.pone.0111006 [OPEN ACCESS]
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** Pinter, M; Hucke, F; Zielonke, N; Trauner, M; Sieghart, W; Peck-Radosavljevic, M Epidemiological trends of hepatocellular carcinoma in Austria.
Dig Dis. 2014; 32(6):664-669 Doi: 10.1159/000367983
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** Pinter, M; Hucke, F; Zielonke, N; Waldhör, T; Trauner, M; Peck-Radosavljevic, M; Sieghart, W Incidence and mortality trends for biliary tract cancers in Austria.
Liver Int. 2014; 34(7):1102-1108 Doi: 10.1111/liv.12325
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** Rupp, C; Rössler, A; Halibasic, E; Sauer, P; Weiss, KH; Friedrich, K; Wannhoff, A; Stiehl, A; Stremmel, W; Trauner, M; Gotthardt, DN Reduction in alkaline phosphatase is associated with longer survival in primary sclerosing cholangitis, independent of dominant stenosis.
Aliment Pharmacol Ther. 2014; 40(11-12): 1292-1301. Doi: 10.1111/apt.12979 [OPEN ACCESS]
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** Salzl, P; Reiberger, T; Ferlitsch, M; Payer, BA; Schwengerer, B; Trauner, M; Peck-Radosavljevic, M; Ferlitsch, A Evaluation of portal hypertension and varices by acoustic radiation force impulse imaging of the liver compared to transient elastography and AST to platelet ratio index.
Ultraschall Med. 2014; 35(6):528-533 Doi: 10.1055/s-0034-1366506
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** Schwabl, P; Payer, BA; Grahovac, J; Klein, S; Horvatits, T; Mitterhauser, M; Stift, J; Boucher, Y; Trebicka, J; Trauner, M; Angermayr, B; Fuhrmann, V; Reiberger, T; Peck-Radosavljevic, M Pioglitazone decreases portosystemic shunting by modulating inflammation and angiogenesis in cirrhotic and non-cirrhotic portal hypertensive rats.
J Hepatol. 2014; 60(6): 1135-1142. Doi: 10.1016/j.jhep.2014.01.025
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** Stättermayer, AF; Rutter, K; Beinhardt, S; Wrba, F; Scherzer, TM; Strasser, M; Hofer, H; Steindl-Munda, P; Trauner, M; Ferenci, P Role of FDFT1 polymorphism for fibrosis progression in patients with chronic hepatitis C.
Liver Int. 2014; 34(3): 388-395. Doi: 10.1111/liv.12269
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** Stättermayer, AF; Strassl, R; Maieron, A; Rutter, K; Stauber, R; Strasser, M; Beinhardt, S; Datz, C; Scherzer, TM; Steindl-Munda, P; Gschwantler, M; Trauner, M; Hofer, H; Ferenci, P Polymorphisms of interferon-λ4 and IL28B - effects on treatment response to interferon/ribavirin in patients with chronic hepatitis C.
Aliment Pharmacol Ther. 2014; 39(1):104-111 Doi: 10.1111/apt.12547 [OPEN ACCESS]
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** Valkovič, L; Gajdošík, M; Traussnigg, S; Wolf, P; Chmelík, M; Kienbacher, C; Bogner, W; Krebs, M; Trauner, M; Trattnig, S; Krššák, M Application of localized ³¹P MRS saturation transfer at 7 T for measurement of ATP metabolism in the liver: reproducibility and initial clinical application in patients with non-alcoholic fatty liver disease.
Eur Radiol. 2014; 24(7): 1602-1609. Doi: 10.1007/s00330-014-3141-x
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** Woolbright, BL; Li, F; Xie, Y; Farhood, A; Fickert, P; Trauner, M; Jaeschke, H Lithocholic acid feeding results in direct hepato-toxicity independent of neutrophil function in mice.
Toxicol Lett. 2014; 228(1):56-66 Doi: 10.1016/j.toxlet.2014.04.001 [OPEN ACCESS]
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** Wree, A; Schlattjan, M; Bechmann, LP; Claudel, T; Sowa, JP; Stojakovic, T; Scharnagl, H; Köfeler, H; Baba, HA; Gerken, G; Feldstein, AE; Trauner, M; Canbay, A Adipocyte cell size, free fatty acids and apolipoproteins are associated with non-alcoholic liver injury progression in severely obese patients.
Metabolism. 2014; 63(12):1542-1552 Doi: 10.1016/j.metabol.2014.09.001
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** Yang, M; Ramachandran, A; Yan, HM; Woolbright, BL; Copple, BL; Fickert, P; Trauner, M; Jaeschke, H Osteopontin is an initial mediator of inflammation and liver injury during obstructive cholestasis after bile duct ligation in mice.
Toxicol Lett. 2014; 224(2):186-195 Doi: 10.1016/j.toxlet.2013.10.030 [OPEN ACCESS]
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** Zollner, G; Thueringer, A; Lackner, C; Fickert, P; Trauner, M Alterations of canalicular ATP-binding cassette transporter expression in drug-induced liver injury.
Digestion. 2014; 90(2):81-88 Doi: 10.1159/000365003
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Review

** Baghdasaryan, A; Chiba, P; Trauner, M Clinical application of transcriptional activators of bile salt transporters.
Mol Aspects Med. 2014; 37:57-76 Doi: 10.1016/j.mam.2013.12.001 [OPEN ACCESS]
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** Cuperus, FJ; Claudel, T; Gautherot, J; Halilbasic, E; Trauner, M The role of canalicular ABC transporters in cholestasis.
Drug Metab Dispos. 2014; 42(4):546-560 Doi: 10.1124/dmd.113.056358 [OPEN ACCESS]
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** Cuperus, FJ; Halilbasic, E; Trauner, M Fibrate treatment for primary biliary cirrhosis.
Curr Opin Gastroenterol. 2014; 30(3): 279-286. Doi: 10.1097/MOG.0000000000000056
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** Fickert, P; Pollheimer, MJ; Beuers, U; Lackner, C; Hirschfield, G; Housset, C; Keitel, V; Schramm, C; Marschall, HU; Karlsen, TH; Melum, E; Kaser, A; Eksteen, B; Strazzabosco, M; Manns, M; Trauner, M; International PSC Study Group (IPSCSG) Characterization of animal models for primary sclerosing cholangitis (PSC).
J Hepatol. 2014; 60(6):1290-1303 Doi: 10.1016/j.jhep.2014.02.006 [OPEN ACCESS]
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** Fuchs, CD; Claudel, T; Trauner, M Role of metabolic lipases and lipolytic metabolites in the pathogenesis of NAFLD.
Trends Endocrinol Metab. 2014; 25(11):576-585 Doi: 10.1016/j.tem.2014.08.001
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** Rudashevskaya, EL; Stockner, T; Trauner, M; Freissmuth, M; Chiba, P Pharmacological correction of misfolding of ABC proteins.
Drug Discov Today Technol. 2014; 12(12):e87-e94 Doi: 10.1016/j.ddtec.2014.03.009 [OPEN ACCESS]
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** Schaap, FG; Trauner, M; Jansen, PL Bile acid receptors as targets for drug development.
Nat Rev Gastroenterol Hepatol. 2014; 11(1):55-67 Doi: 10.1038/nrgastro.2013.151 [OPEN ACCESS]
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** Staufer, K; Halilbasic, E; Trauner, M; Kazemi-Shirazi, L Cystic fibrosis related liver disease--another black box in hepatology.
Int J Mol Sci. 2014; 15(8):13529-13549 Doi: 10.3390/ijms150813529 [OPEN ACCESS]
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** Trauner, M; Halilbasic, E; Kazemi-Shirazi, L; Kienbacher, C; Staufer, K; Traussnigg, S; Hofer, H Therapeutic role of bile acids and nuclear receptor agonists in fibrosing cholangiopathies.
Dig Dis. 2014; 32(5):631-636 Doi: 10.1159/000360517
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Abstract (Journal)

** Fuchs, CD; Paumgartner, G; Wahlstrom, A; Chiba, P; Stojakovic, T; Claudel, T; Marschall, HU; Trauner, M Absence of BSEP/ABCB11 protects from cholestatic liver injury in mice.
HEPATOLOGY. 2014; 60: 405A-406A.-65th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD); NOV 07-11, 2014; Boston, USA. [Poster]
Web of Science

 

** Hofer, H; Zollner, G; Fickert, P; Graziadei, I; Trauner, M Clinical Course And Outcome Of Patients With Sclerosing Cholangitis In Critically Ill Patients (Sc-Cip): High Mortality Without Liver Transplantation
HEPATOLOGY. 2014; 60: 354A-354A.-65th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases; NOV 07-11, 2014; Boston, MA. [Poster]
Web of Science

 

** Krones, E; Glaenzer, D; Durchschein, F; Kirsch, A; Eller, K; Trauner, M; Rosenkranz, AR; Fickert, P Urinary NGAL Levels Reflect the Therapeutic Effects of norUDCA in Mice with Cholemic Nephropathy
HEPATOLOGY. 2014; 60: 329A-329A.-65th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases; NOV 07-11, 2014; Boston, MA. [Poster]
Web of Science

 

** Krones, E; Glanzer, D; Durchschein, F; Kirsch, A; Eller, K; Trauner, M; Rosenkranz, A; Fickert, P Urinary NGAL Levels reflect the therapeutic Effects of norUDCA in the Mouse Model of cholemic Nephropathy
WIEN KLIN WOCHENSCHR. 2014; 126(17-18):577-577.-65th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases; NOV 07-11, 2014; Boston, MA. [Poster]
Web of Science

 

** Rutter, K; Horvatits, T; Drolz, A; Fauler, G; Heinz, G; Hulsmann, M; Trauner, M; Fuhrmann, V IMPACT OF TOTAL SERUM BILE ACIDS IN CRITICALLY ILL PATIENTS
INTENS CARE MED. 2014; 40: S286-S286.-27th Annual Congress of the European-Society-of-Intensive-Care-Medicine (ESICM); SEP 27-OCT 01, 2014; Barcelona, SPAIN. [Poster]
Web of Science

 

Comment

** Stojakovic, T; Claudel, T; Trauner, M Editorial for 'randomized controlled trial assessing the effect of simvastatin in primary biliary cirrhosis'.
Liver Int. 2014; 34(3):328-329 Doi: 10.1111/liv.12359 [OPEN ACCESS]
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2013

Full paper/article (Journal)

** Acimovic, J; Lövgren-Sandblom, A; Olin, M; Ali, Z; Heverin, M; Schüle, R; Schöls, L; Fischler, B; Fickert, P; Trauner, M; Björkhem, I Sulphatation does not appear to be a protective mechanism to prevent oxysterol accumulation in humans and mice.
PLoS One. 2013; 8(7):e68031-e68031 Doi: 10.1371/journal.pone.0068031 [OPEN ACCESS]
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** Angelberger, S; Reinisch, W; Makristathis, A; Lichtenberger, C; Dejaco, C; Papay, P; Novacek, G; Trauner, M; Loy, A; Berry, D Temporal bacterial community dynamics vary among ulcerative colitis patients after fecal microbiota transplantation.
Am J Gastroenterol. 2013; 108(10):1620-1630 Doi: 10.1038/ajg.2013.257
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** Fickert, P; Krones, E; Pollheimer, MJ; Thueringer, A; Moustafa, T; Silbert, D; Halilbasic, E; Yang, M; Jaeschke, H; Stokman, G; Wells, RG; Eller, K; Rosenkranz, AR; Eggertsen, G; Wagner, CA; Langner, C; Denk, H; Trauner, M Bile acids trigger cholemic nephropathy in common bile-duct-ligated mice.
Hepatology. 2013; 58(6):2056-2069 Doi: 10.1002/hep.26599 [OPEN ACCESS]
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** Fickert, P; Pollheimer, MJ; Silbert, D; Moustafa, T; Halilbasic, E; Krones, E; Durchschein, F; Thüringer, A; Zollner, G; Denk, H; Trauner, M Differential effects of norUDCA and UDCA in obstructive cholestasis in mice.
J Hepatol. 2013; 58(6):1201-1208 Doi: 10.1016/j.jhep.2013.01.026 [OPEN ACCESS]
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** Huang, J; Das, SK; Jha, P; Al Zoughbi, W; Schauer, S; Claudel, T; Sexl, V; Vesely, P; Birner-Gruenberger, R; Kratky, D; Trauner, M; Hoefler, G The PPARα agonist fenofibrate suppresses B-cell lymphoma in mice by modulating lipid metabolism.
Biochim Biophys Acta. 2013; 1831(10):1555-1565 Doi: 10.1016/j.bbalip.2013.04.012 [OPEN ACCESS]
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** Mandorfer, M; Neukam, K; Reiberger, T; Payer, BA; Rivero, A; Puoti, M; Boesecke, C; Baumgarten, A; Grzeszczuk, A; Zangerle, R; Meyer-Olson, D; Rockstroh, JK; Trauner, M; Pineda, JA; Peck-Radosavljevic, M The impact of interleukin 28B rs12979860 single nucleotide polymorphism and liver fibrosis stage on response-guided therapy in HIV/HCV-coinfected patients.
AIDS. 2013; 27(17): 2707-2714. Doi: 10.1097/01.aids.0000432460.44593.ef
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** Mandorfer, M; Reiberger, T; Payer, BA; Ferlitsch, A; Breitenecker, F; Aichelburg, MC; Obermayer-Pietsch, B; Rieger, A; Trauner, M; Peck-Radosavljevic, M; Vienna HIV & Liver Study Group Low vitamin D levels are associated with impaired virologic response to PEGIFN + RBV therapy in HIV-hepatitis C virus coinfected patients.
AIDS. 2013; 27(2):227-232 Doi: 10.1097/QAD.0b013e32835aa161 [OPEN ACCESS]
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** Marzioni, M; Saccomanno, S; Agostinelli, L; Rychlicki, C; De Minicis, S; Pierantonelli, I; Trauner, M; Fickert, P; Müller, T; Shanmukhappa, K; Trozzi, L; Candelaresi, C; Baroni, GS; Benedetti, A PDX-1/Hes-1 interactions determine cholangiocyte proliferative response to injury in rodents: possible implications for sclerosing cholangitis.
J Hepatol. 2013; 58(4):750-756 Doi: 10.1016/j.jhep.2012.11.033
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** Peck-Radosavljevic, M; Angermayr, B; Datz, C; Ferlitsch, A; Ferlitsch, M; Fuhrmann, V; Häfner, M; Kramer, L; Maieron, A; Payer, B; Reiberger, T; Stauber, R; Steininger, R; Trauner, M; Thurnher, S; Ulbrich, G; Vogel, W; Zoller, H; Graziadei, I; Austrian Society of Gastroenterology and Hepatology Austrian consensus on the definition and treatment of portal hypertension and its complications (Billroth II).
Wien Klin Wochenschr. 2013; 125(7-8):200-219 Doi: 10.1007/s00508-013-0337-z
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** Pinter, M; Sieghart, W; Schmid, M; Dauser, B; Prager, G; Dienes, HP; Trauner, M; Peck-Radosavljevic, M Hedgehog inhibition reduces angiogenesis by downregulation of tumoral VEGF-A expression in hepatocellular carcinoma.
United European Gastroenterol J. 2013; 1(4):265-275 Doi: 10.1177/2050640613496605 [OPEN ACCESS]
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** Rainer, PP; Primessnig, U; Harenkamp, S; Doleschal, B; Wallner, M; Fauler, G; Stojakovic, T; Wachter, R; Yates, A; Groschner, K; Trauner, M; Pieske, BM; von Lewinski, D Bile acids induce arrhythmias in human atrial myocardium--implications for altered serum bile acid composition in patients with atrial fibrillation.
Heart. 2013; 99(22):1685-1692 Doi: 10.1136/heartjnl-2013-304163
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** Reinhart, K; Bannert, C; Dunkler, D; Salzl, P; Trauner, M; Renner, F; Knoflach, P; Ferlitsch, A; Weiss, W; Ferlitsch, M Prevalence of flat lesions in a large screening population and their role in colonoscopy quality improvement.
Endoscopy. 2013; 45(5):350-356 Doi: 10.1055/s-0032-1326348
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Review

** Fuchs, C; Claudel, T; Trauner, M Bile acid-mediated control of liver triglycerides.
Semin Liver Dis. 2013; 33(4):330-342 Doi: 10.1055/s-0033-1358520
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** Halilbasic, E; Baghdasaryan, A; Trauner, M Nuclear receptors as drug targets in cholestatic liver diseases.
Clin Liver Dis. 2013; 17(2):161-189 Doi: 10.1016/j.cld.2012.12.001 [OPEN ACCESS]
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Abstract (Journal)

** Bettermann, K; Mehta, AK; Lederer, E; Ernst, C; Kessler, SM; Chen, X; Hoshida, Y; Bardeesy, N; Fuchs, BC; Tanabe, KK; Müller, H; Svendova, V; Schimek, MG; Mach, M; Speicher, MR; Mahajan, V; Stumptner, C; Thueringer, A; Stojakovic, T; Longerich, T; Schirmacher, P; Magin, TM; Strnad, P; Fuchs, CD; Trauner, M; Spilka, R; Kiemer, AK; Teufel, A; Maass, T; Moriggl, R; Campbell, JS; Thorgeirsson, SS; Stauffer, J; Karin, M; Llovet, JM; Zatloukal, K; Lackner, C; Haybäck, J Steatohepatitis-associated Hepatocellular Carcinoma: Evidence of a Keratinopathy.
HEPATOLOGY. 2013; 58(S1):543A-543A.-64th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD); NOV 1-5, 2013; Washington, DC, USA. [Poster]
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** Fuchs, CD; Claudel, T; Halilbasic, E; Jha, P; Spindelboeck, W; Stojakovic, T; Trauner, M FXR controlled CHOP as novel key player in NAFLD progression.
HEPATOLOGY. 2013; 58(S1):542A-542A.-64th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD); NOV 1-5, 2013; Washington, DC, USA. [Poster]
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** Fuchs, CD; Claudel, T; Halilbasic, E; Stojakovic, T; Trauner, M INTRAHEPATIC CHANGES IN BILE ACID COMPOSITION PROTECTS BSEP (ABCB11) KO MICE FROM HEPATIC INFLAMMATION IN METHIONINE CHOLINE DEFICIENT DIET INDUCED NASH.
J HEPATOL. 2013; 58(S1):S32-S32.-48th Annual Meeting of the European Association for the Study of the Liver (EASL); APR 24-28, 2013; Amsterdam, THE NETHERLANDS. Doi: 10.1016/S0168-8278(13)60072-0 [Oral Communication]
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** Krones, E; Pollheimer, MJ; Deutschmann, A; Kinslechner, K; Durchschein, F; Eller, K; Rosenkranz, A; Trauner, M; Fickert, P norUDCA AMELIORATES CHOLEMIC NEPHROPATHY IN LONG-TERM COMMON BILE DUCT LIGATED MICE
J HEPATOL. 2013; 58: S43-S43. Doi: 10.1016/S0168-8278(13)60100-2 [Oral Communication]
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** Mandorfer, M; Reiberger, T; Payer, BA; Breitenecker, F; Aichelburg, MC; Obermayer-Pietsch, B; Rieger, A; Puoti, M; Zangerle, R; Trauner, M; Peck-Radosavljevic, M REVISTING PREDICTORS OF VIROLOGIC RESPONSE TO PEGIFN plus RBV THERAPY IN HIV/HCV COINFECTED PATIENTS: THE ROLE OF METABOLIC FACTORS AND ELEVATED GGT LEVELS
J HEPATOL. . 2013; 58: S352-S353.-International Liver Congress / 48th Annual Meeting of the European-Association-for-the-Study-of-the-Liver (EASL); APR 24-28, 2013; Amsterdam, NETHERLANDS. Doi: 10.1016/S0168-8278(13)60862-4 [Poster]
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** Mueller, M; Marschall, HU; Claudel, T; Wagner, M; Fickert, P; Lackner, C; Einarsson, C; Thorell, A; Trauner, M URSODEOXYCHOLIC ACID COUNTERACTS LIPOTOXICITY AND INDUCES UNFOLDED PROTEIN RESPONSE IN MORBIDLY OBESE PATIENTS
J HEPATOL. . 2013; 58: S517-S517.-International Liver Congress / 48th Annual Meeting of the European-Association-for-the-Study-of-the-Liver (EASL); APR 24-28, 2013; Amsterdam, NETHERLANDS. Doi: 10.1016/S0168-8278(13)61279-9 [Poster]
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** Pollheimer, MJ; Bowlus, C; Lackner, C; Karlsen, TH; Hov, JR; Lyman, S; Adamkewicz, J; Mikels-Vigdal, A; Marshall, D; Smith, V; Trauner, M; Fickert, P LYSYL OXIDASE-LIKE 2 (LOXL2) PROTEIN IS INDUCED IN HUMAN CHOLESTATIC LIVER DISEASE AND IN ANIMAL MODELS OF CHOLANGIOPATHIES
J HEPATOL. 2013; 58: S281-S282. Doi: 10.1016/S0168-8278(13)60696-0 [Poster]
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** Rutter, K; Ferlitsch, A; Maieron, A; Stattermayer, AF; Graziadei, I; Dulic, M; Gschwantler, M; Stauber, R; Hofer, H; Peck-Radosavljevic, M; Vogel, W; Trauner, M; Ferenci, P SAFETY OF TRIPLE THERAPY WITH TELAPREVIR OR BOCEPREVIR IN HEPATITIS C PATIENTS WITH ADVANCED LIVER DISEASE - PREDICTIVE FACTORS FOR SEPSIS
J HEPATOL. . 2013; 58: S30-S30.-International Liver Congress / 48th Annual Meeting of the European-Association-for-the-Study-of-the-Liver (EASL); APR 24-28, 2013; Amsterdam, NETHERLANDS. Doi: 10.1016/S0168-8278(13)60067-7 [Poster]
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** Teckman, J; Fickert, P; Trauner, M Autophagy is induced by the bile acid norUDCA, which may be a potential therapy for alpha-1-antitrypsin deficiency
HEPATOLOGY. .. 2013; 58: 257A-257A.-64th Annual Meeting and Postgraduate Course of the American-Association-for-the-Study-of-Liver-Diseases; NOV 01-05, 2013; Washington, DC. [Poster]
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Comment

** Trauner, M; Fickert, P; Tilg, H Bile acids as modulators of gut microbiota linking dietary habits and inflammatory bowel disease: a potentially dangerous liaison.
Gastroenterology. 2013; 144(4):844-846 Doi: 10.1053/j.gastro.2013.02.029
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2012

Full paper/article (Journal)

** Bernhardt, GA; Zollner, G; Cerwenka, H; Kornprat, P; Fickert, P; Bacher, H; Werkgartner, G; Müller, G; Zatloukal, K; Mischinger, HJ; Trauner, M Hepatobiliary transporter expression and post-operative jaundice in patients undergoing partial hepatectomy.
Liver Int. 2012; 32(1):119-127 Doi: 10.1111/j.1478-3231.2011.02625.x
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** Chennamsetty, I; Claudel, T; Kostner, KM; Trauner, M; Kostner, GM FGF19 signaling cascade suppresses APOA gene expression.
Arterioscler Thromb Vasc Biol. 2012; 32(5):1220-1227 Doi: 10.1161/ATVBAHA.111.243055 [OPEN ACCESS]
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** Chennamsetty, I; Kostner, KM; Claudel, T; Vinod, M; Frank, S; Weiss, TS; Trauner, M; Kostner, GM Nicotinic acid inhibits hepatic APOA gene expression: studies in humans and in transgenic mice.
J Lipid Res. 2012; 53(11):2405-2412 Doi: 10.1194/jlr.M029769 [OPEN ACCESS]
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** Fuchs, CD; Claudel, T; Kumari, P; Haemmerle, G; Pollheimer, MJ; Stojakovic, T; Scharnagl, H; Halilbasic, E; Gumhold, J; Silbert, D; Koefeler, H; Trauner, M Absence of adipose triglyceride lipase protects from hepatic endoplasmic reticulum stress in mice.
Hepatology. 2012; 56(1):270-280 Doi: 10.1002/hep.25601 [OPEN ACCESS]
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** Haybaeck, J; Stumptner, C; Thueringer, A; Kolbe, T; Magin, TM; Hesse, M; Fickert, P; Tsybrovskyy, O; Müller, H; Trauner, M; Zatloukal, K; Denk, H Genetic background effects of keratin 8 and 18 in a DDC-induced hepatotoxicity and Mallory-Denk body formation mouse model.
Lab Invest. 2012; 92(6):857-867 Doi: 10.1038/labinvest.2012.49 [OPEN ACCESS]
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** Lax, S; Schauer, G; Prein, K; Kapitan, M; Silbert, D; Berghold, A; Berger, A; Trauner, M Expression of the nuclear bile acid receptor/farnesoid X receptor is reduced in human colon carcinoma compared to nonneoplastic mucosa independent from site and may be associated with adverse prognosis.
Int J Cancer. 2012; 130(10): 2232-2239. Doi: 10.1002/ijc.26293 [OPEN ACCESS]
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** Marschall, HU; Wagner, M; Zollner, G; Fickert, P; Silbert, D; Gustafsson, U; Sahlin, S; Trauner, M Combined rifampicin and ursodeoxycholic acid treatment does not amplify rifampicin effects on hepatic detoxification and transport systems in humans.
Digestion. 2012; 86(3):244-249 Doi: 10.1159/000341420
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** Modica, S; Petruzzelli, M; Bellafante, E; Murzilli, S; Salvatore, L; Celli, N; Di Tullio, G; Palasciano, G; Moustafa, T; Halilbasic, E; Trauner, M; Moschetta, A Selective activation of nuclear bile acid receptor FXR in the intestine protects mice against cholestasis.
Gastroenterology. 2012; 142(2):355-65.e1-355-65.e4 Doi: 10.1053/j.gastro.2011.10.028 [OPEN ACCESS]
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** Moustafa, T; Fickert, P; Magnes, C; Guelly, C; Thueringer, A; Frank, S; Kratky, D; Sattler, W; Reicher, H; Sinner, F; Gumhold, J; Silbert, D; Fauler, G; Höfler, G; Lass, A; Zechner, R; Trauner, M Alterations in lipid metabolism mediate inflammation, fibrosis, and proliferation in a mouse model of chronic cholestatic liver injury.
Gastroenterology. 2012; 142(1):140-151 Doi: 10.1053/j.gastro.2011.09.051
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** Putz-Bankuti, C; Pilz, S; Stojakovic, T; Scharnagl, H; Pieber, TR; Trauner, M; Obermayer-Pietsch, B; Stauber, RE Association of 25-hydroxyvitamin D levels with liver dysfunction and mortality in chronic liver disease.
Liver Int. 2012; 32(5):845-851 Doi: 10.1111/j.1478-3231.2011.02735.x
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** Starmann, J; Fälth, M; Spindelböck, W; Lanz, KL; Lackner, C; Zatloukal, K; Trauner, M; Sültmann, H Gene expression profiling unravels cancer-related hepatic molecular signatures in steatohepatitis but not in steatosis.
PLoS One. 2012; 7(10):e46584-e46584 Doi: 10.1371/journal.pone.0046584 [OPEN ACCESS]
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** von Haehling, S; Schefold, JC; Jankowska, EA; Springer, J; Vazir, A; Kalra, PR; Sandek, A; Fauler, G; Stojakovic, T; Trauner, M; Ponikowski, P; Volk, HD; Doehner, W; Coats, AJ; Poole-Wilson, PA; Anker, SD Ursodeoxycholic acid in patients with chronic heart failure: a double-blind, randomized, placebo-controlled, crossover trial.
J Am Coll Cardiol. 2012; 59(6): 585-592. Doi: 10.1016/j.jacc.2011.10.880 [OPEN ACCESS]
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Review

** Bechmann, LP; Hannivoort, RA; Gerken, G; Hotamisligil, GS; Trauner, M; Canbay, A The interaction of hepatic lipid and glucose metabolism in liver diseases.
J Hepatol. 2012; 56(4):952-964 Doi: 10.1016/j.jhep.2011.08.025 [OPEN ACCESS]
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** Krones, E; Graziadei, I; Trauner, M; Fickert, P Evolving concepts in primary sclerosing cholangitis.
Liver Int. 2012; 32(3):352-369 Doi: 10.1111/j.1478-3231.2011.02607.x [OPEN ACCESS]
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** Trauner, M; Halilbasic, E; Baghdasaryan, A; Moustafa, T; Krones, E; Fickert, P; Hofer, H; Penner, E Primary sclerosing cholangitis: new approaches to diagnosis, surveillance and treatment.
Dig Dis. 2012; 30 Suppl 1(6):39-47 Doi: 10.1159/000341123
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Abstract (Journal)

** Durchschein, F; Pollheimer, MJ; Krones, E; Zollner, G; Trauner, M; Fickert, P Genetic Loss of Muscarine-3 Receptor Decreases Biliary Bicarbonate Secretion and Aggravates Cholestatic Liver Injury in Mice
HEPATOLOGY. 2012; 56: 334A-334A.-63rd Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD); NOV 09-13, 2012; Boston, MA.
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** Fuchs, C; Claudel, T; Kumari, P; Stojakovic, T; Halilbasic, E; Spindelboeck, W; Gonzalez, F; Trauner, M FXR IS A KEY PLAYER IN NAFLD DEVELOPMENT BY CONTROLLING CHOP EXPRESSION.
J HEPATOL. 2012; 56(S2):S490-S490.-47th Annual Meeting of the European Association for the Study of the Liver (EASL); APR 18-22, 2012; Barcelona, SPAIN. Doi: 10.1016/S0168-8278(12)61248-3 [Poster]
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** Fuchs, CD; Claudel, T; Stojakovic, T; Haemmerle, G; Trauner, M Changes in hepatic bile acid composition protect BSEP (ABCB11) KO mice from hepatic inflammation in methionine choline deficient (MCD)-diet induced NASH.
HEPATOLOGY. 2012; 56: 873A-874A.-63rd Annual Meeting of the American Association for the Study of Liver Diseases (AASLD); NOV 09-13, 2012; Boston, USA. [Poster]
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** Halilbasic, E; Claudel, T; Bachhofner, N; Kapusta, C; Fickert, P; Trauner, M Norursodeoxycholic Acid Counteracts Hepatic Acute Phase Response via Modulation of NF kappa B Signaling
HEPATOLOGY. 2012; 56: 539A-540A.-63rd Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD); NOV 09-13, 2012; Boston, MA.
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** Krones, E; Pollheimer, MJ; Durchschein, F; Trauner, M; Fickert, P The effects of bile acids on renal collecting duct epithelial cell death - are bile acids the culprits in cholemic nephropathy?
HEPATOLOGY. 2012; 56: 544A-545A.-63rd Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD); NOV 09-13, 2012; Boston, MA. [Poster]
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** Marschall, HU; Mueller, M; Wagner, M; Fickert, P; Zollner, G; Silbert, D; Lackner, C; Thorell, A; Trauner, M HIGH LEVELS OF URSODEOXYCHOLIC ACID ACT AS FXR ANTAGONIST AND DEPLETE LIVER CHOLESTEROL DUE TO INCREASED BILE ACID SYNTHESIS IN MORBIDLY OBESE PATIENTS
J HEPATOL. . 2012; 56: S515-S515.-47th Annual Meeting of the European-Association-for-the-Study-of-the-Liver (EASL); APR 18-22, 2012; Barcelona, SPAIN. Doi: 10.1016/S0168-8278(12)61319-1 [Poster]
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** Marzioni, M; Saccomanno, S; Agostinelli, L; Rychlicki, C; Pierantonelli, I; Trauner, M; Fickert, P; Mueller, T; Shanmukhappa, SK; Trozzi, L; De Minicis, S; Candelaresi, C; Svegliati-Baroni, G; Benedetti, A PDX-1/Hes-1 interaction is a determinant of cholangiocyte proliferative response in Sclerosing Cholangitis
HEPATOLOGY. 2012; 56: 207A-207A.-63rd Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD); NOV 09-13, 2012; Boston, MA.
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** Marzioni, M; Saccomanno, S; Agostinelli, L; Rychlicki, C; Pierantonelli, I; Trauner, M; Fickert, P; Muller, T; Shanmukhappa, K; Alpini, G; Trozzi, L; De Minicis, S; Candelaresi, C; Baroni, GS; Benedetti, A PDX-1/HES-1 INTERACTIONS DETERMINE CHOLANGIOCYTE PROLIFERATIVE RESPONSE TO INJURY: THE SIGNIFICANCE FOR SCLEROSING CHOLANGITIS
J HEPATOL. 2012; 56: S16-S16.-47th Annual Meeting of the European-Association-for-the-Study-of-the-Liver (EASL); APR 18-22, 2012; Barcelona, SPAIN. Doi: 10.1016/S0168-8278(12)60050-6
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** Putz-Bankuti, C; Pilz, S; Meinitzer, A; Maerz, W; Kienreich, K; Stojakovic, T; Trauner, M; Pieber, TR; Stauber, RE ASSOCIATION OF HOMOARGININE AND METHYLARGININES WITH LIVER DYSFUNCTION AND MORTALITY IN CIRRHOTIC PATIENTS.
J HEPATOL. 2012; 56(S2):S255-S255.-47th Annual Meeting of the European Association for the Study of the Liver (EASL); APR 18-22, 2012; Barcelona, SPAIN. Doi: 10.1016/S0168-8278(12)60656-4 [Poster]
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** Salzl, P; Wagner, D; Koenig, V; Heinisch, BB; Payer, BA; Ferlitsch, M; Reiberger, T; Schwarzer, R; Trauner, M; Peck-Radosavljevic, M; Ferlitsch, A Vitamin D3 levels predict survival but not portal hypertension in patients with liver cirrhosis
HEPATOLOGY. 2012; 56: 925A-925A.-63rd Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD); NOV 09-13, 2012; Boston, MA.
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** Stiedl, P; Blaas, L; Stanek, V; Musteanu, M; Zollner, G; Esterbauer, H; Eferl, R; Trauner, M; Casanova, E ROLE OF GROWTH HORMONE RECEPTOR IN LIVER FIBROSIS
J HEPATOL. 2012; 56: S147-S147.-47th Annual Meeting of the European-Association-for-the-Study-of-the-Liver (EASL); APR 18-22, 2012; Barcelona, SPAIN. Doi: 10.1016/S0168-8278(12)60376-6
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2011

Full paper/article (Journal)

** Baghdasaryan, A; Claudel, T; Gumhold, J; Silbert, D; Adorini, L; Roda, A; Vecchiotti, S; Gonzalez, FJ; Schoonjans, K; Strazzabosco, M; Fickert, P; Trauner, M Dual farnesoid X receptor/TGR5 agonist INT-767 reduces liver injury in the Mdr2-/- (Abcb4-/-) mouse cholangiopathy model by promoting biliary HCO⁻₃ output.
Hepatology. 2011; 54(4):1303-1312 Doi: 10.1002/hep.24537 [OPEN ACCESS]
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** Beraza, N; Ofner-Ziegenfuss, L; Ehedego, H; Boekschoten, M; Bischoff, SC; Mueller, M; Trauner, M; Trautwein, C Nor-ursodeoxycholic acid reverses hepatocyte-specific nemo-dependent steatohepatitis.
Gut. 2011; 60(3):387-396 Doi: 10.1136/gut.2010.223834
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** Chennamsetty, I; Claudel, T; Kostner, KM; Baghdasaryan, A; Kratky, D; Levak-Frank, S; Frank, S; Gonzalez, FJ; Trauner, M; Kostner, GM Farnesoid X receptor represses hepatic human APOA gene expression.
J Clin Invest. 2011; 121(9):3724-3734 Doi: 10.1172/JCI45277 [OPEN ACCESS]
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** Das, SK; Eder, S; Schauer, S; Diwoky, C; Temmel, H; Guertl, B; Gorkiewicz, G; Tamilarasan, KP; Kumari, P; Trauner, M; Zimmermann, R; Vesely, P; Haemmerle, G; Zechner, R; Hoefler, G Adipose triglyceride lipase contributes to cancer-associated cachexia.
Science. 2011; 333(6039):233-238 Doi: 10.1126/science.1198973 [OPEN ACCESS]
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** Ferlitsch, M; Reinhart, K; Pramhas, S; Wiener, C; Gal, O; Bannert, C; Hassler, M; Kozbial, K; Dunkler, D; Trauner, M; Weiss, W Sex-specific prevalence of adenomas, advanced adenomas, and colorectal cancer in individuals undergoing screening colonoscopy.
JAMA. 2011; 306(12):1352-1358 Doi: 10.1001/jama.2011.1362 [OPEN ACCESS]
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** Fiorotto, R; Scirpo, R; Trauner, M; Fabris, L; Hoque, R; Spirli, C; Strazzabosco, M Loss of CFTR affects biliary epithelium innate immunity and causes TLR4-NF-κB-mediated inflammatory response in mice.
Gastroenterology. 2011; 141(4): 1508.e1- 1508.e5 Doi: 10.1053/j.gastro.2011.06.052 [OPEN ACCESS]
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** Haemmerle, G; Moustafa, T; Woelkart, G; Büttner, S; Schmidt, A; van, de, Weijer, T; Hesselink, M; Jaeger, D; Kienesberger, PC; Zierler, K; Schreiber, R; Eichmann, T; Kolb, D; Kotzbeck, P; Schweiger, M; Kumari, M; Eder, S; Schoiswohl, G; Wongsiriroj, N; Pollak, NM; Radner, FP; Preiss-Landl, K; Kolbe, T; Rülicke, T; Pieske, B; Trauner, M; Lass, A; Zimmermann, R; Hoefler, G; Cinti, S; Kershaw, EE; Schrauwen, P; Madeo, F; Mayer, B; Zechner, R ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-α and PGC-1.
Nat Med. 2011; 17(9):1076-85 Doi: 10.1038/nm.2439 [OPEN ACCESS]
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** Marschall, HU; Wagner, M; Zollner, G; Fickert, P; Lackner, C; Thorell, A; Trauner, M Ursodeoxycholic acid for treatment of fatty liver disease and dyslipidemia in morbidly obese patients.
Dig Dis. 2011; 29(1):117-118 Doi: 10.1159/000324146
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** Reiberger, T; Rutter, K; Ferlitsch, A; Payer, BA; Hofer, H; Beinhardt, S; Kundi, M; Ferenci, P; Gangl, A; Trauner, M; Peck-Radosavljevic, M Portal pressure predicts outcome and safety of antiviral therapy in cirrhotic patients with hepatitis C virus infection.
Clin Gastroenterol Hepatol. 2011; 9(7):602-608 Doi: 10.1016/j.cgh.2011.03.002
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** Zhang, G; Chen, M; Graham, D; Subsin, B; McDougall, C; Gilady, S; Kneteman, M; Law, L; Swain, M; Trauner, M; Wrzesinski, S; Flavell, R; Wasilenko, S; Mason, A Mouse mammary tumor virus in anti-mitochondrial antibody producing mouse models.
J Hepatol. 2011; 55(4):876-884 Doi: 10.1016/j.jhep.2011.01.037
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Short report/Letter

** Kniepeiss, D; Wagner, D; Krause, R; Aigelsreiter, A; Iberer, F; Fickert, P; Tscheliessnigg, KH; Trauner, M Mycosis as a cause of secondary sclerosing cholangitis requiring liver retransplantation.
Transplantation. 2011; 91(2):e14-e16 Doi: 10.1097/TP.0b013e318200ba57 (- Case Report) [OPEN ACCESS]
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Review

** Claudel, T; Zollner, G; Wagner, M; Trauner, M Role of nuclear receptors for bile acid metabolism, bile secretion, cholestasis, and gallstone disease.
Biochim Biophys Acta. 2011; 1812(8):867-878 Doi: 10.1016/j.bbadis.2010.12.021 [OPEN ACCESS]
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** Fuhrmann, V; Drolz, A; Trauner, M Extracorporeal artificial liver support systems in the management of intractable cholestatic pruritus.
Liver Int. 2011; 31 Suppl 3(9):31-33 Doi: 10.1111/j.1478-3231.2011.02584.x
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** Penz-Österreicher, M; Österreicher, CH; Trauner, M Fibrosis in autoimmune and cholestatic liver disease.
Best Pract Res Clin Gastroenterol. 2011; 25(2):245-258 Doi: 10.1016/j.bpg.2011.02.001 [OPEN ACCESS]
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** Pollheimer, MJ; Halilbasic, E; Fickert, P; Trauner, M Pathogenesis of primary sclerosing cholangitis.
Best Pract Res Clin Gastroenterol. 2011; 25(6):727-739 Doi: 10.1016/j.bpg.2011.10.009 [OPEN ACCESS]
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** Pollheimer, MJ; Trauner, M; Fickert, P Will we ever model PSC? - "it's hard to be a PSC model!".
Clin Res Hepatol Gastroenterol. 2011; 35(12):792-804 Doi: 10.1016/j.clinre.2011.04.014
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** Tannapfel, A; Denk, H; Dienes, HP; Langner, C; Schirmacher, P; Trauner, M; Flott-Rahmel, B Histopathological diagnosis of non-alcoholic and alcoholic fatty liver disease.
Virchows Arch. 2011; 458(5): 511-523. Doi: 10.1007/s00428-011-1066-1 [OPEN ACCESS]
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** Trauner, M; Baghdasaryan, A; Claudel, T; Fickert, P; Halilbasic, E; Moustafa, T; Zollner, G Targeting nuclear bile acid receptors for liver disease.
Dig Dis. 2011; 29(1):98-102 Doi: 10.1159/000324141
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** Trauner, M; Halilbasic, E Nuclear receptors as new perspective for the management of liver diseases.
Gastroenterology. 2011; 140(4):1120-1125.e1-1120-1125.12 Doi: 10.1053/j.gastro.2011.02.044
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** Wagner, M; Zollner, G; Trauner, M Nuclear receptors in liver disease.
HEPATOLOGY. 2011; 53(3): 1023-1034. Doi: 10.1002/hep.24148 [OPEN ACCESS]
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Editorial

** Fuhrmann, V; Derfler, K; Trauner, M Extracorporeal artificial liver support in hepatic failure: pathfinder, bridge to recovery or dead end street?
Liver Int. 2011; 31 Suppl 3(9):iv-iv Doi: 10.1111/j.1478-3231.2011.02581.x
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Abstract (Journal)

** Baghdasaryan, A; Claudel, T; Gumhold, J; Silbert, D; Adorini, L; Gonzalez, F; Schoonjans, K; Fickert, P; Trauner, M FXR BUT NOT TGR5 ACTIVATION STIMULATES HCO3-RICH BILE SECRETION AND AMELIORATES LIVER DAMAGE IN MDR2-/- (ABCB4-/-) MOUSE MODEL OF CHRONIC LIVER INJURY
HEPATOLOGY. 2011; 54: 425A-425A.-62nd Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD); NOV 04-08, 2011; San Francisco, CA. [Oral Communication]
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** Fickert, P; Silbert, D; Moustafa, T; Halilbasic, E; Krones, E; Durchschein, F; Thueringer, A; Pollheimer, MJ; Zollner, G; Denk, H; Trauner, M DIFFERENTIAL EFFECTS OF NORUDCA AND UDCA IN OBSTRUCTIVE CHOLESTASIS IN MICE
HEPATOLOGY. 2011; 54: 775A-775A.-62nd Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD); NOV 04-08, 2011; San Francisco, CA. [Poster]
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** Fickert, P; Thueringer, A; Moustafa, T; Silbert, D; Yang, M; Jaeschke, H; Stokman, G; Wells, R; Eller, K; Rosenkranz, AR; Eggertsen, G; Denk, H; Trauner, M TUBULOINTERSTITIAL KIDNEY FIBROSIS AND CHRONIC RENAL FAILURE IN LONG-TERM COMMON BILE-DUCT-LIGATED MICE AS A RESULT OF COLLECTING DUCT INJURY: THE ROLE OF OSTEOPONTIN, FXR, AND CYP8B1
HEPATOLOGY. 2011; 54: 1250A-1251A.-62nd Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD); NOV 04-08, 2011; San Francisco, CA.
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** Fickert, P; Thueringer, A; Moustafa, T; Yang, M; Jaeschke, H; Wells, RG; Stokman, G; Denk, H; Trauner, M LONG-TERM COMMON BILE DUCT-LIGATION IN MICE INDUCES TUBULOINTERSTITIAL KIDNEY FIBROSIS AND CHRONIC RENAL FAILURE: ROLE OF BILE ACID NUCLEAR RECEPTOR FXR AND OSTEOPONTIN
J HEPATOL. 2011; 54: S244-S244.-46th Annual Meeting of the European-Association-for-the-Study-of-the-Liver (EASL); 2011; Berlin, GERMANY. Doi: 10.1016/S0168-8278(11)60602-8
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** Fuchs, CD; Claudel, T; Kumari, P; Stojakovic, T; Haemmerle, G; Halilbasic, E; Gumhold, J; Silbert, D; Koefeler, H; Zechner, R; Trauner, M ATGL (PNPLA2) KNOCKOUT MICE ARE PROTECTED FROM HEPATIC ER-STRESS VIA OLEIC ACID ACCUMULATION.
J HEPATOL. 2011; 54: S41-S42.-46th Annual Meeting of the European Association for the Study of the Liver (EASL); MAR 30-APR 3, 2011; Berlin, GERMANY. Doi: 10.1016/S0168-8278(11)60095-0 [Poster]
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** Fuchs, CD; Claudel, T; Stojakovic, T; Silbert, D; Maurer, B; Trauner, M BSEP (ABCB11) KO MICE ARE PROTECTED FROM HEPATIC INFLAMMATION IN METHIONINE CHOLINE DEFICIENT DIET INDUCED NASH.
HEPATOLOGY. 2011; 54: 1169A-1169A.-62nd Annual Meeting of the American Association for the Study of Liver Diseases (AASLD); NOV 04-08, 2011; San Francisco, USA. [Poster]
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** Grunhage, F; Hochrath, K; Krawczyk, M; Obermayer-Pietsch, B; Trauner, M; Lammert, F ASSOCIATION OF COMMON SNPS OF GENES REGULATING VITAMIN D HOMEOSTASIS WITH VITAMIN D LEVELS AND LIVER FIBROSIS IN A COHORT OF PATIENTS WITH CHRONIC LIVER DISEASE
ANTICANCER RES. 2011; 31(4):41-
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** Grunhage, F; Hochrath, K; Krawczyk, M; Obermayer-Pietsch, B; Trauner, M; Lammert, F ASSOCIATION OF GENES REGULATING VITAMIN D HOMEOSTASIS WITH VITAMIN D LEVELS AND LIVER FIBROSIS IN A COHORT OF PATIENTS WITH CHRONIC LIVER DISEASE
J HEPATOL. 2011; 54: S48-S49.-46th Annual Meeting of the European-Association-for-the-Study-of-the-Liver (EASL); 2011; Berlin, GERMANY.
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** Grunhage, F; Hochrath, K; Krawczyk, M; Obermayer-Pietsch, B; Trauner, M; Lammert, F GENETIC CONTROL OF VITAMIN D LEVELS AND LIVER FIBROSIS BY VARIANTS IN GENES REGULATING VITAMIN D HOMOEOSTASIS IN A COHORT OF PATIENTS WITH CHRONIC LIVER DISEASE
HEPATOLOGY. 2011; 54: 1217A-1218A.-62nd Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD); NOV 04-08, 2011; San Francisco, CA.
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** Hochrath, K; Krawczyk, M; Obermayer-Pietsch, B; Trauner, M; Lammert, F; Grunhage, F SERUM 25-HYDROXY-VITAMIN D-3 IN CHRONIC LIVER DISEASE: A TRANSIENT ELASTOGRAPHY-BASED STUDY
ANTICANCER RES. 2011; 31(4):43-
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** Kumari, P; Claudel, T; Kofeler, H; Schittmayer, M; Grunberger, RB; Baghdasaryan, A; Das, S; Zechner, R; Hofler, G; Trauner, M ADIPOSE TRIGLYCERIDE LIPASE (PNPLA2) IS A NOVEL KEY PLAYER IN PROTECTION FROM NASH
HEPATOLOGY. 2011; 54: 1154A-1154A.-62nd Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD); NOV 04-08, 2011; San Francisco, CA. [Poster]
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** Pollheimer, MJ; Fickert, P; Langner, C; Karlsen, TH; Trauner, M ADHESION MOLECULE EXPRESSION PATTERN IN PRIMARY SCLEROSING CHOLANGITIS AND DISEASE CONTROLS
J HEPATOL. 2011; 54: S516-S516. Doi: 10.1016/S0168-8278(11)61312-3 [Poster]
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2010

Full paper/article (Journal)

** Baghdasaryan, A; Claudel, T; Kosters, A; Gumhold, J; Silbert, D; Thüringer, A; Leski, K; Fickert, P; Karpen, SJ; Trauner, M Curcumin improves sclerosing cholangitis in Mdr2-/- mice by inhibition of cholangiocyte inflammatory response and portal myofibroblast proliferation.
Gut. 2010; 59(4):521-530 Doi: 10.1136/gut.2009.186528 [OPEN ACCESS]
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** Blaas, L; Kornfeld, JW; Schramek, D; Musteanu, M; Zollner, G; Gumhold, J; van Zijl, F; Schneller, D; Esterbauer, H; Egger, G; Mair, M; Kenner, L; Mikulits, W; Eferl, R; Moriggl, R; Penninger, J; Trauner, M; Casanova, E Disruption of the growth hormone--signal transducer and activator of transcription 5--insulinlike growth factor 1 axis severely aggravates liver fibrosis in a mouse model of cholestasis.
Hepatology. 2010; 51(4):1319-1326 Doi: 10.1002/hep.23469 [OPEN ACCESS]
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** Denk, GU; Maitz, S; Wimmer, R; Rust, C; Invernizzi, P; Ferdinandusse, S; Kulik, W; Fuchsbichler, A; Fickert, P; Trauner, M; Hofmann, AF; Beuers, U Conjugation is essential for the anticholestatic effect of NorUrsodeoxycholic acid in taurolithocholic acid-induced cholestasis in rat liver.
Hepatology. 2010; 52(5): 1758-1768. Doi: 10.1002/hep.23911 [OPEN ACCESS]
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** Fickert, P; Thueringer, A; Moustafa, T; Silbert, D; Gumhold, J; Tsybrovskyy, O; Lebofsky, M; Jaeschke, H; Denk, H; Trauner, M The role of osteopontin and tumor necrosis factor alpha receptor-1 in xenobiotic-induced cholangitis and biliary fibrosis in mice.
Lab Invest. 2010; 90(6):844-852 Doi: 10.1038/labinvest.2010.61 [OPEN ACCESS]
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** Mair, M; Zollner, G; Schneller, D; Musteanu, M; Fickert, P; Gumhold, J; Schuster, C; Fuchsbichler, A; Bilban, M; Tauber, S; Esterbauer, H; Kenner, L; Poli, V; Blaas, L; Kornfeld, JW; Casanova, E; Mikulits, W; Trauner, M; Eferl, R Signal transducer and activator of transcription 3 protects from liver injury and fibrosis in a mouse model of sclerosing cholangitis.
Gastroenterology. 2010; 138(7):2499-2508 Doi: 10.1053/j.gastro.2010.02.049
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** Morgan, RE; Trauner, M; van Staden, CJ; Lee, PH; Ramachandran, B; Eschenberg, M; Afshari, CA; Qualls, CW; Lightfoot-Dunn, R; Hamadeh, HK Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Toxicol Sci. 2010; 118(2):485-500 Doi: 10.1093/toxsci/kfq269 [OPEN ACCESS]
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** Stojakovic, T; Claudel, T; Putz-Bankuti, C; Fauler, G; Scharnagl, H; Wagner, M; Sourij, H; Stauber, RE; Winkler, K; März, W; Wascher, TC; Trauner, M Low-dose atorvastatin improves dyslipidemia and vascular function in patients with primary biliary cirrhosis after one year of treatment.
Atherosclerosis. 2010; 209(1): 178-183. Doi: 10.1016/j.atherosclerosis.2009.08.052
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** Stojakovic, T; Scharnagl, H; Trauner, M; Pieske, B; Wellnitz, B; Seelhorst, U; Schilling, D; Winkelmann, BR; Boehm, BO; März, W Serum gamma-glutamyl transferase and mortality in persons undergoing coronary angiography-The Ludwigshafen Risk and Cardiovascular Health Study.
Atherosclerosis. 2010; 208(2):564-571 Doi: 10.1016/j.atherosclerosis.2009.07.026
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** Tannapfel, A; Denk, H; Dienes, HP; Langner, C; Schirmacher, P; Trauner, M; Flott-Rahmel, B Histopathological diagnose of non-alcoholic and alcoholic fatty liver disease.
Z Gastroenterol. 2010; 48(4): 486-498. Doi: 10.1055/s-0029-1245278
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** Trottier, J; El Husseini, D; Perreault, M; Pâquet, S; Caron, P; Bourassa, S; Verreault, M; Inaba, TT; Poirier, GG; Bélanger, A; Guillemette, C; Trauner, M; Barbier, O The human UGT1A3 enzyme conjugates norursodeoxycholic acid into a C23-ester glucuronide in the liver.
J Biol Chem. 2010; 285(2):1113-1121 Doi: 10.1074/jbc.M109.073908 [OPEN ACCESS]
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Review

** Tannapfel, A; Denk, H; Dienes, HP; Langner, C; Schirmacher, P; Trauner, M; Flott-Rahmel, B Histopathological diagnosis of non-alcoholic and alcoholic fatty liver disease. Grade 2 consensus-based guidelines.
Pathologe. 2010; 31(3): 225-237. Doi: 10.1007/s00292-010-1274-5
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** Trauner, M; Arrese, M; Wagner, M Fatty liver and lipotoxicity.
Biochim Biophys Acta. 2010; 1801(3): 299-310. Doi: 10.1016/j.bbalip.2009.10.007 [OPEN ACCESS]
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** Trauner, M; Claudel, T; Fickert, P; Moustafa, T; Wagner, M Bile acids as regulators of hepatic lipid and glucose metabolism.
Dig Dis. 2010; 28(1):220-224 Doi: 10.1159/000282091
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** Trauner, M; Fickert, P; Baghdasaryan, A; Claudel, T; Halilbasic, E; Moustafa, T; Wagner, M; Zollner, G New insights into autoimmune cholangitis through animal models.
Dig Dis. 2010; 28(1):99-104 Doi: 10.1159/000282072
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** Wagner, M; Zollner, G; Trauner, M Nuclear receptor regulation of the adaptive response of bile acid transporters in cholestasis.
SEMIN LIVER DIS. 2010; 30(2): 160-177. Doi: 10.1055/s-0030-1253225 [OPEN ACCESS]
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** Zollner, G; Wagner, M; Trauner, M Nuclear receptors as drug targets in cholestasis and drug-induced hepatotoxicity.
Pharmacol Ther. 2010; 126(3):228-243 Doi: 10.1016/j.pharmthera.2010.03.005
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Abstract (Journal)

** Baghdasaryan, A; Claudel, T; Gumhold, J; Silbert, D; Halsegger, S; Adorini, L; Strazzabosco, M; Fickert, P; Trauner, M THERAPEUTIC TARGETING OF NUCLEAR AND MEMBRANE BILE ACID RECEPTORS IN A MOUSE MODEL OF CHRONIC CHOLESTASIS
HEPATOLOGY. 2010; 52(4):724--The 61st Annual Meeting of the Americal Association fro teh Study of liver Diseases; OCT 29-NOV 02, 2010; Boston, MA, USA. [Poster]
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** Baghdasaryan, A; Claudel, T; Gumhold, J; Silbert, D; Halsegger, S; Volkl, R; Adorini, L; Fickert, P; Trauner, M THERAPEUTIC EFFECTS OF FXR AND TGR5 ACTIVATION IN THE MDR2 (ABCB4)(-/-) MOUSE MODEL OF SCLEROSING CHOLANGITIS
J HEPATOL. 2010; 52: S354-S354.-45th Annual Meeting of the European Association for the Study of the Liver; APR 14 - 18,2010; Vienna, AUSTRIA. Doi: 10.1016/S0168-8278(10)60914-2 [Oral Communication]
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** Beraza, N; Ofner-Ziegenfuss, L; Ehedego, H; Boekschoten, M; Mueller, M; Trauner, M; Trautwein, C NOR-UDCA ATTENUATES PROGRESSION OF NASH
J HEPATOL. 2010; 52: S304-S304. Doi: 10.1016/S0168-8278(10)60783-0 [Poster]
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** Fiorotto, R; Scirpo, R; Spirli, C; Trauner, M; Strazzabosco, M LACK OF CFTR AFFECTS THE INNATE IMMUNITY OF THE BILIARY EPITHELIUM AND DETERMINES A TLR4/NF-kappa B-MEDIATED INFLAMMATORY RESPONSE
J HEPATOL. 2010; 52: S20-S20. Doi: 10.1016/S0168-8278(10)60047-5 [Poster]
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** Fiorotto, R; Scirpo, R; Spirli, C; Trauner, MH; Strazzabosco, M ALTERED REGULATION OF TLR4 IN THE BILIARY EPITHELIUM OF CFTR-DEFECTIVE MICE DETERMINES AN INFLAMMATORY PHENOTYPE AND CAUSES LIVER DAMAGE AFTER INDUCTION OF DSS COLITIS
HEPATOLOGY. 2010; 52(4): 196
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** Fuchs, CD; Moustafa, T; Haemmerle, G; Halilbasic, E; Gumhold, J; Silbert, D; Fickert, P; Zechner, R; Trauner, M ADIPOSE TRIGLYCERIDE LIPASE (ATGL) IS A NOVEL MODULATOR OF HEPATIC ER-STRESS
J HEPATOL. 2010; 52: S305-S305.-45th Annual Meeting of the European Association for the Study of the Liver; APR 14 - 18,2010; Vienna, AUSTRIA. Doi: 10.1016/S0168-8278(10)60787-8 [Oral Communication]
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** Halilbasic, E; Claudel, T; Gumhold, J; Halsegger, S; Silbert, D; Fickert, P; Trauner, M PREGNANCY RESOLVES LIVER FIBROSIS AND IMPROVES SCLEROSING CHOLANGITIS IN MDR2 (ABCB4) -/- MICE VIA DIRECT ANTI-INFLAMMATORY EFFECTS OF SEX HORMONES
J HEPATOL. 2010; 52: S24-S24.-45th Annual Meeting of the European Association for the Study of the Liver; APR 14 - 18,2010; Vienna, AUSTRIA. Doi: 10.1016/S0168-8278(10)60052-9 [Oral Communication]
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** Krones, E; Halilbasic, E; Grisold, A; Krause, R; Trauner, M; Fickert, P; Zollner, G Acute hepatitis species as a result of contamination of a food supplement with Cytotoxin-producing Bacillus species.
WIEN KLIN WOCHENSCHR. 2010; 122(17-18):A10-A11. [Poster]
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** Kumari, P; Claudel, T; Kofeler, H; Schittmayer, M; Grunberger, RB; Zechner, R; Hofler, G; Trauner, M ADIPOSE TRIGLYCERIDE LIPASE (ATGL) IS A NOVEL KEY PLAYER IN PROTECTION FROM ACUTE HEPATIC INFLAMMATION
J HEPATOL. 2010; 52: S19-S19.-International Liver Congress™ 2010 – the 45th annual meeting of the European Association for the Study of the Liver (EASL) ; APR 14 -18, 2010; Doi: 10.1016/S0168-8278(10)60045-1 [Oral Communication]
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** Marschall, HU; Luketic, VA; Mason, AL; Lindor, KD; Hirschfield, GM; Gordon, SC; Mayo, MJ; Kowdley, KV; Pares, A; Trauner, M; Eliot, L; Hofmann, AF; Sciacca, CI; Shapiro, DA THE FARNESOID X RECEPTOR (FXR) AGONIST OBETICHOLIC ACID (INT-747, 6 alpha-ETHYL CHENODEOXYCHOLIC ACID) IN COMBINATION WITH URSODEOXYCHOLIC ACID (UDCA) INCREASES PLASMA FGF-19 CONCENTRATIONS BUT NOT BILE ACID CONCENTRATION OR PROFILE IN PRIMARY BILIARY CIRRHOSIS (PBC)
HEPATOLOGY. 2010; 52(4): 73
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** Mason, A; Luketic, V; Lindor, K; Hirschfield, G; Gordon, S; Mayo, M; Kowdley, K; Pares, A; Trauner, M; Castelloe, E; Sciacca, C; Jones, TB; Bohm, O; Shapiro, D FARNESOID-X RECEPTOR AGONISTS: A NEW CLASS OF FOR THE TREATMENT OF PBC? AN INTERNATIONAL STUDY EVALUATING THE ADDITION OF INT-747 TO URSODEOXYCHOLIC ACID
J HEPATOL. 2010; 52: S1-S2. Doi: 10.1016/S0168-8278(10)60004-9 [Poster]
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** Mason, AL; Luketic, VA; Lindor, KD; Hirschfield, GM; Gordon, SC; Mayo, MJ; Kowdley, KV; Pares, A; Trauner, M; Sciacca, CI; Jones, TB; Pruzanski, M; Shapiro, DA FARNESOID-X RECEPTOR AGONISTS: A NEW CLASS OF DRUGS FOR THE TREATMENT OF PBC? AN INTERNATIONAL STUDY EVALUATING THE ADDITION OF OBETICHOLIC ACID (INT-747) TO URSODEOXYCHOLIC ACID
HEPATOLOGY. 2010; 52(4): 75
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** Moustafa, T; Fickert, P; Magnes, C; Frank, S; Kratky, D; Sinner, F; Gumhold, J; Silbert, D; Halsegger, S; Trauner M METABOLIC REPROGRAMMING OF LIPID METABOLISM BY THE SIDE-CHAIN MODIFIED BILE ACID, 24-NORURSODEOXYCHOLIC ACID, RESTORES INFLAMMATION-DRIVEN LIVER INJURY AND ABERRANT PROLIFERATION IN ABCB4-/- MICE
J HEPATOL. 2010; 52: S20-S21.-45th Annual Meeting of the European Association for the Study of the Liver; APR 14 - 18,2010; Vienna, AUSTRIA. Doi: 10.1016/S0168-8278(10)60049-9 [Oral Communication]
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** Putz-Bankuti, C; Stojakovic, T; Scharnagl, H; Bauer, B; Pock, H; Trauner, M; Stauber, R Reduction of serum leptin levels during antiviral treatment with peginterferon and ribavirin in patients with chronic hepatitis C
WIEN KLIN WOCHENSCHR. 2010; 122(17-18):A10-A10.-41. Jahrestagung der Österreichischen Gesellschaft für Innere Medizin (ÖGIM); SEP 29-OCT 2; Salzburg, AUSTRIA. [Poster]
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** Rainer, PP; Huber, MS; Edelmann, F; Stojakovic, T; Trantina-Yates, A; Trauner, M; Pieske, BM; Von Lewinski, D The primary bile-salt glycocholate induces arrhythmias in human atrial myocardium
CARDIOVASC RES. 2010; 87: S50-S50. [Poster]
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** Stojakovic, T; Claudel, T; Putz-Bankuti, C; Fauler, G; Scharnagl, H; Wagner, M; Sourij, H; Stauber, RE; Winkler, K; Marz, W; Wascher, TC; Trauner, M LOW-DOSE ATORVASTATIN IMPROVES DYSLIPIDEMIA AND VASCULAR FUNCTION IN PATIENTS WITH PRIMARY BILIARY CIRRHOSIS AFTER ONE YEAR OF TREATMENT.
J HEPATOL. 2010; 52: S431-S432.-45th Annual Meeting of the European Association for the Study of the Liver (EASL); APR 14-18, 2010; Vienna, AUSTRIA. Doi: 10.1016/S0168-8278(10)61118-X [Poster]
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** Stojakovic, T; Putz-Bankuti, C; Scharnagl, H; Bauer, B; Pock, H; Trauner, M; Stauber, RE EFFECTS OF ANTIVIRAL TREATMENT ON SERUM LEPTIN LEVELS AND LIPID PROFILE IN PATIENTS WITH CHRONIC HEPATITIS C
ATHEROSCLER SUPPL. 2010; 11(2): MS456-78th Congress of the European Atherosclerosis Society; JUN 20-23, 2010; Hamburg, GERMANY. Doi: 10.1016/S1567-5688(10)70957-0
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** Wagner, D; Dobnig, H; Kniepeiss, D; Iberer, F; Tscheliessnigg, K; Pieber, T; Obermayer, B; Trauner, M; Fahrleitner, A Vitamin D Deficiency, Hyperparathyroidism and Bone Turnover in Patients Listed for Liver Transplantation (LTX).
AM J TRANSPLANT. 2010; 10: 350-350.-Annual Meeting of the American Society of Transplantation; MAY 2-8; San Diego, California. [Oral Communication]
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** Zollner, G; Thueringer, A; Lackner, C; Fickert, P; Trauner, M ALTERATIONS OF CANALICULAR ATP-BINDING CASSETTE TRANSPORTERS IN PATIENTS WITH DRUG-INDUCED LIVER INJURY
J HEPATOL. 2010; 52: S449-S449.-45th Annual Meeting of the European Association for the Study of the Liver; APR 14 - 18,2010; Vienna, AUSTRIA. Doi: 10.1016/S0168-8278(10)61163-4 [Poster]
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Meeting Report

** Karpen, SJ; Trauner, M The new therapeutic frontier--nuclear receptors and the liver.
J Hepatol. 2010; 52(3):455-462 Doi: 10.1016/j.jhep.2009.12.002
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2009

Full paper/article (Journal)

** European Association for the Study of the Liver (with Trauner, M) EASL Clinical Practice Guidelines: management of cholestatic liver diseases.
J Hepatol. 2009; 51(2): 237-267. Doi: 10.1016/j.jhep.2009.04.009
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** Fickert, P; Fuchsbichler, A; Moustafa, T; Wagner, M; Zollner, G; Halilbasic, E; Stöger, U; Arrese, M; Pizarro, M; Solís, N; Carrasco, G; Caligiuri, A; Sombetzki, M; Reisinger, E; Tsybrovskyy, O; Zatloukal, K; Denk, H; Jaeschke, H; Pinzani, M; Trauner, M Farnesoid X receptor critically determines the fibrotic response in mice but is expressed to a low extent in human hepatic stellate cells and periductal myofibroblasts.
Am J Pathol. 2009; 175(6):2392-2405 Doi: 10.2353/ajpath.2009.090114 [OPEN ACCESS]
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** Fickert, P; Fuchsbichler, A; Wagner, M; Silbert, D; Zatloukal, K; Denk, H; Trauner, M The role of the hepatocyte cytokeratin network in bile formation and resistance to bile acid challenge and cholestasis in mice.
Hepatology. 2009; 50(3):893-899 Doi: 10.1002/hep.23068 [OPEN ACCESS]
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** Halilbasic, E; Fiorotto, R; Fickert, P; Marschall, HU; Moustafa, T; Spirli, C; Fuchsbichler, A; Gumhold, J; Silbert, D; Zatloukal, K; Langner, C; Maitra, U; Denk, H; Hofmann, AF; Strazzabosco, M; Trauner, M Side chain structure determines unique physiologic and therapeutic properties of norursodeoxycholic acid in Mdr2-/- mice.
Hepatology. 2009; 49(6):1972-1981 Doi: 10.1002/hep.22891 [OPEN ACCESS]
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** Jahnel, J; Fickert, P; Langner, C; Högenauer, C; Silbert, D; Gumhold, J; Fuchsbichler, A; Trauner, M Impact of experimental colitis on hepatobiliary transporter expression and bile duct injury in mice.
Liver Int. 2009; 29(9):1316-1325 Doi: 10.1111/j.1478-3231.2009.02044.x
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** Klein, K; Kullak-Ublick, GA; Wagner, M; Trauner, M; Eloranta, JJ Hepatocyte nuclear factor-4alpha and bile acids regulate human concentrative nucleoside transporter-1 gene expression.
Am J Physiol Gastrointest Liver Physiol. 2009; 296(4): G936-G947. Doi: 10.1152/ajpgi.90678.2008 [OPEN ACCESS]
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** Kratzer, A; Buchebner, M; Pfeifer, T; Becker, TM; Uray, G; Miyazaki, M; Miyazaki-Anzai, S; Ebner, B; Chandak, PG; Kadam, RS; Calayir, E; Rathke, N; Ahammer, H; Radovic, B; Trauner, M; Hoefler, G; Kompella, UB; Fauler, G; Levi, M; Levak-Frank, S; Kostner, GM; Kratky, D Synthetic LXR agonist attenuates plaque formation in apoE-/- mice without inducing liver steatosis and hypertriglyceridemia.
J Lipid Res. 2009; 50(2): 312-326. Doi: 10.1194/jlr.M800376-JLR200 [OPEN ACCESS]
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** Loebermann, M; Sombetzki, M; Langner, C; Fuchsbichler, A; Gumhold, J; Silbert, D; Riebold, D; Holtfreter, M; Fickert, P; Nizze, H; Trauner, M; Reisinger, EC Imbalance of pro- and antifibrogenic genes and bile duct injury in murine Schistosoma mansoni infection-induced liver fibrosis.
Trop Med Int Health. 2009; 14(11):1418-1425 Doi: 10.1111/j.1365-3156.2009.02387.x [OPEN ACCESS]
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** Stauber, RE; Wagner, D; Stadlbauer, V; Palma, S; Gurakuqi, G; Kniepeiss, D; Iberer, F; Smolle, KH; Haas, J; Trauner, M Evaluation of indocyanine green clearance and model for end-stage liver disease for estimation of short-term prognosis in decompensated cirrhosis.
Liver Int. 2009; 29(10):1516-1520 Doi: 10.1111/j.1478-3231.2009.02104.x
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Review

** Sturm, E; Wagner, M; Trauner, M Nuclear receptor ligands in therapy of cholestatic liver disease.
Front Biosci. 2009; 14(6):4299-4325 Doi: 10.2741/3529
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** Wagner, M; Zollner, G; Trauner, M New molecular insights into the mechanisms of cholestasis.
J Hepatol. 2009; 51(3): 565-580. Doi: 10.1016/j.jhep.2009.05.012 [OPEN ACCESS]
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** Zollner, G; Trauner, M Nuclear receptors as therapeutic targets in cholestatic liver diseases.
Br J Pharmacol. 2009; 156(1):7-27 Doi: 10.1111/j.1476-5381.2008.00030.x [OPEN ACCESS]
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Abstract (Journal)

** Beraza, N; Ofner-Ziegenfuss, L; Ehedego, H; Boekschoten, MV; Muller, M; Trauner, M; Trautwein, C THERAPEUTIC EFFECT OF A NOR-UDCA BASED DIET ON NASH PROGRESSION IN THE CHRONIC DISEASE MODEL OF HEPATOCYTE-SPECIFIC NEMO DELETION
HEPATOLOGY. 2009; 50(4):1920- [Oral Communication]
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** Blaas, L; Kornfield, JW; Zollner, G; Schramek, D; Esterbauer, H; Trauner, M; Casanova, E ROLE OF STAT5 IN LIVER FIBROSIS
J HEPATOL. 2009; 50: 277- Doi: 10.1016/S0168-8278(09)60279-8 [Poster]
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** Jahnel, J; Claudel, T; Baghdasaryan, A; Langner, C; Fickert, P; Trauner, M; Hauer, AC; Silbert, A; Gumhold, J; Fuchsbichler, A PHOSPHOLIPIDS AND COLITIS: IMPACT OF NUTRITIONAL AND BILIARY LACK OF PHOSPHOLIPIDS IN A COLITIS MOUSE MODEL
ACTA PAEDIAT. 2009; 98: 29-30.-50th Annual Meeting of the European Society for Paediatric Research ; October 9-12, 2009 ; Hamburg, Germany. [Oral Communication]
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** Jahnel, J; Raicht, A; Fuchsbichler, A; Schwinger, W; Trauner, M LYMPHOCYTE SUBTYPES IN MDR2 (ABCB4) KNOCKOUT MICE AS MODEL FOR SCLEROSING CHOLANGITIS
J HEPATOL. 2009; 50: 668- Doi: 10.1016/S0168-8278(09)60670-X [Poster]
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** Klein, K; Eloranta, JJ; Wagner, M; Trauner, M; Kullak-Ublick, GA Regulation of human concentrative nucleoside transporter-1 gene expression
NAUNYN-SCHMIED ARCH PHARMACOL. 2009; 379: 490- [Oral Communication]
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** Marschall, HU; Wagner, M; Zollner, G; Fickert, P; Lundasen, T; Gustafsson, U; Sahlin, S; Trauner, M STIMULATION OF HEPATOBILIARY DETOXIFICATION AND TRANSPORT SYSTEMS IN HUMAN LIVER BY COMBINED TREATMENT WITH RIFAMPICIN AND URSODEOXYCHOLIC ACID
J HEPATOL. 2009; 50: 675-Vienna, Austria. Doi: 10.1016/S0168-8278(09)60677-2 [Poster]
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** Stojakovic, T; Putz-Bankuti, C; Fauler, G; Scharnagl, M; Wagner, M; Sourij, H; Stauber, RE; Marz, W; Wascher, TC; Trauner, M Low-dose atorvastatin improves dyslipidemia and vascular function in patients with primary biliary cirrhosis after one year of treatment
WIEN KLIN WOCHENSCHR. 2009; 121(15-16):A26-A26.-40.Jahrestagung der Österreichischen Gesellschaft für Innere Medizin (ÖGIM); SEP 17-19, 2009; Vienna, AUSTRIA. [Poster]
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** Trottier, J; El Husseini, D; Perreault, M; Paquet, S; Caron, P; Trauner, MH; Barbier, O HUMAN UDP-GLUCURONOSYLTRANSFERASE (UGT)1A3 CONJUGATES NORURSODEOXYCHOLIC ACID IN THE LIVER
HEPATOLOGY. 2009; 50(4):1551- [Oral Communication]
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** Wagner, D; Dobnig, H; Kniepeiss, D; Iberer, F; Pieber, TR; Obermayer-Pietsch, BM; Trauner, M; Fahrleitner-Pammer, A Vitamin D deficiency, hyperparathyroidism and bone turnover in patients listed for liver transplantation (LTX): Preliminary results of a cross-sectional study
BONE. 2009; 44(2):S400-S400.-ECTS; June 2009; Vienna; Austria. Doi: 10.1016/j.bone.2009.03.301 [Poster]
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** Wehr, E; Giuliani, A; Trauner, M; Pieber, B; Obermayer-Pietsch, B Abnormal aminotransferase levels are associated with metabolic disturbances in polycystic ovary syndrome
WIEN KLIN WOCHENSCHR. 2009; 121(15-16):A20-A21.-Österreichische Gesellschaft für Innere Medizin; 17.-19.9.2009; Vienna, Austria. [Poster]
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Full paper/article (Proceedings)

** Halilbasic, E; Fickert, P; Fiorotto, R; Marschall, HU; Moustafa, T; Fuchsbichler, A; Gumhold, J; Silbert, D; Langner, C; Maitra, U; Denk, H; Strazzabosco, M; Trauner, M Side-chain modification as critical determinant of the therapeutic properties of 24-norursodeoxycholic acid in Mdr2 (Abcb4) knockout mice
FALK SYMP. 2009; 165: 157-162. [Oral Communication]
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** Trauner, M; Fickert, P; Moustafa, T; Fuchsbichler, A; Claudel, T; Halilbasic, E; Kratky, D; Denk, H Potential role of ursodeoxycholic acid and its side-chain modified derivatives in the treatment of non-alcoholic fatty liver disease and associated atherosclerosis
FALK SYMP. 2009; 165: 151-156. [Oral Communication]
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Comment

** Beuers, U; Trauner, M Ursodeoxycholic acid in primary biliary cirrhosis: Reply.
J Hepatol. 2009; 51(6): 1085-1086. Doi: 10.1016/j.jhep.2009.09.018 [OPEN ACCESS]
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** Fickert, P; Trauner, M When lightning strikes twice: the plot thickens for a dual role of the anion exchanger 2 (AE2/SLC4A2) in the pathogenesis and treatment of primary biliary cirrhosis.
J Hepatol. 2009; 50(3):633-635 Doi: 10.1016/j.jhep.2008.12.006
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2008

Full paper/article (Journal)

** Baghdasaryan, A; Fickert, P; Fuchsbichler, A; Silbert, D; Gumhold, J; Hörl, G; Langner, C; Moustafa, T; Halilbasic, E; Claudel, T; Trauner, M Role of hepatic phospholipids in development of liver injury in Mdr2 (Abcb4) knockout mice.
Liver Int. 2008; 28(7):948-958 Doi: 10.1111/j.1478-3231.2008.01758.x
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** Gurakuqi, GC; Stadlbauer, V; Portugaller, HR; Högenauer, C; Trauner, M; Stauber, RE Fatal hemobilia resulting from an iatrogenic arteriobiliary fistula as a rare complication of transjugular liver biopsy.
Eur J Gastroenterol Hepatol. 2008; 20(1):83-86 Doi: 10.1097/MEG.0b013e3282748f32 (- Case Report)
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** Magnes, C; Suppan, M; Pieber, TR; Moustafa, T; Trauner, M; Haemmerle, G; Sinner, FM Validated comprehensive analytical method for quantification of coenzyme A activated compounds in biological tissues by online solid-phase extraction LC/MS/MS.
Anal Chem. 2008; 80(15):5736-5742 Doi: 10.1021/ac800031u
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Review

** Trauner, M; Fickert, P; Halilbasic, E; Moustafa, T Lessons from the toxic bile concept for the pathogenesis and treatment of cholestatic liver diseases.
Wien Med Wochenschr. 2008; 158(19-20):542-548 Doi: 10.1007/s10354-008-0592-1
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** Zollner, G; Trauner, M Mechanisms of cholestasis.
Clin Liver Dis. 2008; 12(1):1-26 Doi: 10.1016/j.cld.2007.11.010
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Abstract (Journal)

** Baghdasaryan, A; Kosters, A; Claudel, T; Fuchsbichler, A; Gumhold, J; Silbert, D; Leski, K; Fickert, P; Karpen, SJ; Trauner, M Curcumin improves liver injury and biliary fibrosis in MDR2 (ABCB4) knockout mice by inducing anti-oxidative response, but not via modification of bile acid transport/metabolism
J HEPATOL. 2008; 48: S171-S171.-EASL Annual Meeting; April 2008; Milan Italy. Doi: 10.1016/S0168-8278(08)60450-X [Poster]
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** Fickert, P; Moustafa, T; Fuchsbichler, A; Claudel, T; Halilbasic, E; Zatloukal, K; Denk, H; Trauner, M Differential effects of nor UDCA and UDCA in the treatment of fatty liver and arteriosclerosis in western chow-fed ApoE knock out mice
J HEPATOL. 2008; 48: S42-S42.-Annual Meeting, EASL; April 2008; Milann, Italy. Doi: 10.1016/S0168-8278(08)60100-2 [Oral Communication]
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** Graham, D; Chen, M; Zhang, G; Swain, MG; Trauner, MH; Mason, AL THE NOD.C3C4 MOUSE MODEL OF PBC DEVELOPS BOTH MOUSE MAMMARY TUMOR VIRUS AND ABERRANT MITOCHONDRIAL ANTIGEN EXPRESSION IN BILE DUCTS
HEPATOLOGY. 2008; 48(4):653--59th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases; OCT 31-NOV 04, 2008; San Francisco, CA. [Poster]
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** Moustafa, T; Fickert, P; Silbert, D; Gumhold, J; Halilbasic, E; Trauner, MH LOSS OF FXR ATTENUATES SCLEROSING CHOLANGITIS AND BILIARY FIBROSIS IN MDR2(-/-) AND FXR(-/-) DOUBLE KNOCKOUT MICE
HEPATOLOGY. 2008; 48(4):777--59th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases; OCT 31-NOV 04, 2008; San Francisco, CA. [Poster]
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** Moustafa, T; Halilbasic, E; Fickert, P; Fuchsbichler, A; Gumhold, J; Silbert, D; Denk, H; Trauner, M Side chain modified bile acids modulate endoplasmic reticulum stress in Mdr2(-/-) mice in vivo and bile duct epithelial cells in vitro
J HEPATOL. 2008; 48: S54-S55.-EASL Annula Meeting; April 2008; Milan Italy. Doi: 10.1016/S0168-8278(08)60127-0 [Oral Communication]
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** Sombetzki, M; Fickert, P; Loebermann, M; Holtfreter, M; Fuchsbichler, A; Gumhold, J; Silbert, D; Langner, C; Reisinger, EC; Trauner, M 24-nor-ursodeoxycholic acid as novel therapeutic strategy for inflammation-induced liver fibrosis in a murine model of schistosoma mansoni infection
J HEPATOL. 2008; 48: S21-S22.-Annual Meeting, EASL; April 2008; Mailand, Italien. Doi: 10.1016/S0168-8278(08)60052-5 [Oral Communication]
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** Sturm, E; Mulder, J; Stoeger, U; Havinga, R; Baller, JF; Gouw, AS; Kuipers, F; Trauner, MH IMPAIRMENT OF BILE FLOW IN LIVERS AFFECTED BY STEATOSIS OR STEATOHEPATITIS
HEPATOLOGY. 2008; 48(4):806--59th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases; OCT 31-NOV 04, 2008; San Francisco, CA. [Poster]
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Comment

** Wagner, M; Zollner, G; Trauner, M Ischemia and cholestasis: more than (just) the bile ducts!
Transplantation. 2008; 85(8):1083-1085 Doi: 10.1097/TP.0b013e31816b2393
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** Wagner, M; Zollner, G; Trauner, M Nuclear bile acid receptor farnesoid X receptor meets nuclear factor-kappaB: new insights into hepatic inflammation.
Hepatology. 2008; 48(5):1383-1386 Doi: 10.1002/hep.22668 [OPEN ACCESS]
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2007

Full paper/article (Journal)

** Ambros-Rudolph, CM; Glatz, M; Trauner, M; Kerl, H; Müllegger, RR The importance of serum bile acid level analysis and treatment with ursodeoxycholic acid in intrahepatic cholestasis of pregnancy: a case series from central Europe.
Arch Dermatol. 2007; 143(6):757-762 Doi: 10.1001/archderm.143.6.757 (- Case Report) [OPEN ACCESS]
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** Asslaber, M; Abuja, PM; Stark, K; Eder, J; Gottweis, H; Trauner, M; Samonigg, H; Mischinger, HJ; Schippinger, W; Berghold, A; Denk, H; Zatloukal, K The Genome Austria Tissue Bank (GATiB).
Pathobiology. 2007; 74(4):251-258 Doi: 10.1159/000104453 [OPEN ACCESS]
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** Fickert, P; Stöger, U; Fuchsbichler, A; Moustafa, T; Marschall, HU; Weiglein, AH; Tsybrovskyy, O; Jaeschke, H; Zatloukal, K; Denk, H; Trauner, M A new xenobiotic-induced mouse model of sclerosing cholangitis and biliary fibrosis.
Am J Pathol. 2007; 171(2):525-536 Doi: 10.2353/ajpath.2007.061133 [OPEN ACCESS]
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** Geier, A; Dietrich, CG; Trauner, M; Gartung, C Extrahepatic cholestasis downregulates Oatp1 by TNF-alpha signalling without affecting Oatp2 and Oatp4 expression and sodium-independent bile salt uptake in rat liver.
Liver Int. 2007; 27(8):1056-1065 Doi: 10.1111/j.1478-3231.2007.01523.x
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** Panzitt, K; Tschernatsch, MM; Guelly, C; Moustafa, T; Stradner, M; Strohmaier, HM; Buck, CR; Denk, H; Schroeder, R; Trauner, M; Zatloukal, K Characterization of HULC, a novel gene with striking up-regulation in hepatocellular carcinoma, as noncoding RNA.
Gastroenterology. 2007; 132(1):330-342 Doi: 10.1053/j.gastro.2006.08.026
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** Stadlbauer, V; Krisper, P; Beuers, U; Haditsch, B; Schneditz, D; Jung, A; Putz-Bankuti, C; Holzer, H; Trauner, M; Stauber, RE Removal of bile acids by two different extracorporeal liver support systems in acute-on-chronic liver failure.
ASAIO J. 2007; 53(2): 187-193. Doi: 10.1097/01.mat.0000249852.71634.6c [OPEN ACCESS]
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** Stojakovic, T; Putz-Bankuti, C; Fauler, G; Scharnagl, H; Wagner, M; Stadlbauer, V; Gurakuqi, G; Stauber, RE; März, W; Trauner, M Atorvastatin in patients with primary biliary cirrhosis and incomplete biochemical response to ursodeoxycholic acid.
Hepatology. 2007; 46(3):776-784 Doi: 10.1002/hep.21741 [OPEN ACCESS]
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** Wagner, M; Zollner, G; Fickert, P; Gumhold, J; Silbert, D; Fuchsbichler, A; Gujral, JS; Zatloukal, K; Denk, H; Jaeschke, H; Trauner, M Hepatobiliary transporter expression in intercellular adhesion molecule 1 knockout and Fas receptor-deficient mice after common bile duct ligation is independent of the degree of inflammation and oxidative stress.
Drug Metab Dispos. 2007; 35(9):1694-1699 Doi: 10.1124/dmd.107.015610 [OPEN ACCESS]
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** Zollner, G; Fickert, P; Trauner, M Cholestasis
WIEN KLIN WOCHENSCHR. 2007; 119: 125-140. Doi: 10.1007/s11812-007-0029-6
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** Zollner, G; Wagner, M; Fickert, P; Silbert, D; Gumhold, J; Zatloukal, K; Denk, H; Trauner, M Expression of bile acid synthesis and detoxification enzymes and the alternative bile acid efflux pump MRP4 in patients with primary biliary cirrhosis.
Liver Int. 2007; 27(7):920-929 Doi: 10.1111/j.1478-3231.2007.01506.x
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Review

** Fickert, P; Moustafa, T; Trauner, M Primary sclerosing cholangitis--the arteriosclerosis of the bile duct?
Lipids Health Dis. 2007; 6(2):3-3 Doi: 10.1186/1476-511X-6-3 [OPEN ACCESS]
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** Geier, A; Wagner, M; Dietrich, CG; Trauner, M Principles of hepatic organic anion transporter regulation during cholestasis, inflammation and liver regeneration.
Biochim Biophys Acta. 2007; 1773(3): 283-308. Doi: 10.1016/j.bbamcr.2006.04.014 [OPEN ACCESS]
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** Marschall, HU; Wagner, M; Zollner, G; Trauner, M Clinical hepatotoxicity. Regulation and treatment with inducers of transport and cofactors.
MOL PHARM. 2007; 4(6): 895-910. Doi: 10.1021/mp060133c
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** Trauner, M; Fickert, P; Wagner, M MDR3 (ABCB4) defects: a paradigm for the genetics of adult cholestatic syndromes.
Semin Liver Dis. 2007; 27(1):77-98 Doi: 10.1055/s-2006-960172 [OPEN ACCESS]
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Abstract (Journal)

** Geier, A; Dietrich, CG; Trauner, M; Gartung, C Extrahepatic cholestasis down-regulates Oatp1 by TNF-alpha signalling without affecting Oatp2 and Oatp4 expression and sodium-independent bile salt uptake in rat liver
J HEPATOL. 2007; 46: S121-S121.-Annual Meeting, European Asociation for the Study of the Liver; April 11-15, 2007; Barcelona, Spain. Doi: 10.1016/S0168-8278(07)61904-7 [Poster]
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** Genger, M; Mattiassich, G; Trauner, M; Kapitan, M; Lunzer, R; Nadler, K; Rainer, F Long-term tolerance to low-dose methotrexate treatment in elderly patients with chronic polyarthritis. Retrospective analysis of 287 patients.
Z RHEUMATOL. 2007; 66: 89-89. [Oral Communication]
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** Halilbasic, E; Fickert, P; Fuchbichler, A; Langner, C; Gumhold, J; Silbert, D; Maitra, U; Zatloukal, K; Denk, H; Trauner, M Taurine-conjugation critically determines the therapeutic effectiveness of 24-nor-ursodeoxycholic acid (norUDCA) in the treatment of sclerosing cholangitis in Mdr2 (ABCB4) knockout mice
J HEPATOL. 2007; 46: S51-S51.-EASL; April 11-15, 2007; Doi: 10.1016/S0168-8278(07)61714-0 [Oral Communication]
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** Halilbasic, E; Fickert, P; Fuchsbichler, A; Moustafa, T; Stoeger, U; Ueno, Y; Denk, H; Trauner, M TNF alpha and LPS but not bile acids play a key role in the induction of reactive phenotype in bile duct epithelial cells in vitro
J HEPATOL. 2007; 46: S121-S121.-EASL; April 11-15, 2007; Barcelona/Spain. Doi: 10.1016/S0168-8278(07)61905-9 [Poster]
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** Jahnel, J; Wagner, M; Langner, C; Hoegenauer, C; Fickert, P; Silbert, D; Gumhold, J; Fuchsbichler, A; Denk, H; Trauner, M Impact of colitis on bile secretion and hepatobiliary transporter expression in mice possible implications for pathogenesis of sclerosing cholangitis
J HEPATOL. 2007; 46: S122-S122. Doi: 10.1016/S0168-8278(07)61907-2 [Poster]
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** Maitz, S; Wimmer, R; Rust, C; Denk, H; Invernizzi, P; Ferdinandusse, S; Wanders, RJ; Fuchsbichler, A; Fickert, P; Trauner, M; Hofmann, AF; Beuers, U Taurine conjugation is essential for anticholestatic action of norursodeoxycholic acid in taurolithocholic acid-induced cholestasis in rat liver
HEPATOLOGY. 2007; 46(4):338A-339A.-AASLD; NOV 2-6, 2007; Boston, USA. [Poster]
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** Mattiassich, G; Trauner, M; Kapitan, M; Genger, M; Nadler, K; Lunzer, R; Rainer, F The hepatotoxicity of low-dose long-term methotrexate therapy in the treatment of chronic polyarthritis. A retrospective analysis of the liver function parameter in 409 patients.
Z RHEUMATOL. 2007; 66: 85-86. [Oral Communication]
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** Moustafa, T; Fickert, P; Vesely, P; Silbert, D; Gumhold, J; Fuchsbichler, A; Denk, H; Guelly, C; Trauner, M Retention of toxic bile acids activate the mTOR, p70S6k/rps6 signaling pathway in mouse models of cholestatic liver injury
J HEPATOL. 2007; 46: S23-S23. Doi: 10.1016/S0168-8278(07)61646-8 [Oral Communication]
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** Wagner, M; Moustafa, T; Fickert, P; Zollner, G; Gumhold, J; Silbert, D; Fuchsbichler, A; Zatloukal, K; Denk, H; Trauner, M Absence of FXR protects mice from bile-infarcts in biliary obstruction by reduction of bile acid-independent bile flow: Implications for targeting FXR in treatment of cholestasis?
J HEPATOL. 2007; 46: S5-S5.-42th Annual Meeting, European Association for the Study of the Liver; April, 11-15, 2007; Barcelona, Spain. Doi: 10.1016/S0168-8278(07)61603-1 [Oral Communication]
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** Zollner, G; Caligiuri, A; Fickert, P; Wagner, M; Silbert, D; Pinzani, M; Trauner, M Expression of bile acid transport and detoxification systems and their regulatory nuclear receptors in human hepatic stellate cells
J HEPATOL. 2007; 46: S135-S135.-42th Annual Meeting, European Association for the Study of the Liver ; April 11-15, 2007; Barcelona, Spain. Doi: 10.1016/S0168-8278(07)61944-8 [Poster]
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Comment

** Trauner, M A little orphan runs to fat: the orphan receptor small heterodimer partner as a key player in the regulation of hepatic lipid metabolism.
Hepatology. 2007; 46(1):1-5 Doi: 10.1002/hep.21801 [OPEN ACCESS]
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2006

Full paper/article (Journal)

** Boyer, JL; Trauner, M; Mennone, A; Soroka, CJ; Cai, SY; Moustafa, T; Zollner, G; Lee, JY; Ballatori, N Upregulation of a basolateral FXR-dependent bile acid efflux transporter OSTalpha-OSTbeta in cholestasis in humans and rodents.
Am J Physiol Gastrointest Liver Physiol. 2006; 290(6):G1124-G1130 Doi: 10.1152/ajpgi.00539.2005 [OPEN ACCESS]
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** Ellis, E; Wagner, M; Lammert, F; Nemeth, A; Gumhold, J; Strassburg, CP; Kylander, C; Katsika, D; Trauner, M; Einarsson, C; Marschall, HU Successful treatment of severe unconjugated hyperbilirubinemia via induction of UGT1A1 by rifampicin.
J HEPATOL. 2006; 44(1): 243-245. Doi: 10.1016/j.jhep.2005.09.011 (- Case Report)
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** Fickert, P; Fuchsbichler, A; Marschall, HU; Wagner, M; Zollner, G; Krause, R; Zatloukal, K; Jaeschke, H; Denk, H; Trauner, M Lithocholic acid feeding induces segmental bile duct obstruction and destructive cholangitis in mice.
Am J Pathol. 2006; 168(2):410-422 Doi: 10.2353/ajpath.2006.050404 [OPEN ACCESS]
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** Fickert, P; Wagner, M; Marschall, HU; Fuchsbichler, A; Zollner, G; Tsybrovskyy, O; Zatloukal, K; Liu, J; Waalkes, MP; Cover, C; Denk, H; Hofmann, AF; Jaeschke, H; Trauner, M 24-norUrsodeoxycholic acid is superior to ursodeoxycholic acid in the treatment of sclerosing cholangitis in Mdr2 (Abcb4) knockout mice.
Gastroenterology. 2006; 130(2):465-481 Doi: 10.1053/j.gastro.2005.10.018
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** Gurakuqi, GC; Stadlbauer, V; Stepan, V; Warnkross, H; Trauner, M Addison's disease as a rare cause of chronically elevated liver enzymes].
Z Gastroenterol. 2006; 44(2):179-183 Doi: 10.1055/s-2005-858976 (- Case Report)
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** Jung, A; Krisper, P; Haditsch, B; Stauber, RE; Trauner, M; Holzer, H; Schneditz, D Bilirubin kinetic modeling for quantification of extracorporeal liver support.
Blood Purif. 2006; 24(4):413-422 Doi: 10.1159/000094575
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** Marschall, HU; Wagner, M; Bodin, K; Zollner, G; Fickert, P; Gumhold, J; Silbert, D; Fuchsbichler, A; Sjövall, J; Trauner, M Fxr(-/-) mice adapt to biliary obstruction by enhanced phase I detoxification and renal elimination of bile acids.
J Lipid Res. 2006; 47(3):582-592 Doi: 10.1194/jlr.M500427-JLR200 [OPEN ACCESS]
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** Putz-Bankuti, C; Datz, C; März, W; Lackner, C; Stauber, RE; Trauner, M; Toplak, H; Stojakovic, T; Krejs, GJ Clinical-pathological conference series from the Medical University of Graz : case no. 131: elevated transaminases in a 30-year-old male.
Wien Klin Wochenschr. 2006; 118(23-24):769-775 Doi: 10.1007/s00508-006-0718-7 (- Case Report)
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** Zollner, G; Wagner, M; Moustafa, T; Fickert, P; Silbert, D; Gumhold, J; Fuchsbichler, A; Halilbasic, E; Denk, H; Marschall, HU; Trauner, M Coordinated induction of bile acid detoxification and alternative elimination in mice: role of FXR-regulated organic solute transporter-alpha/beta in the adaptive response to bile acids.
Am J Physiol Gastrointest Liver Physiol. 2006; 290(5):G923-G932 Doi: 10.1152/ajpgi.00490.2005 [OPEN ACCESS]
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Short report/Letter

** Marschall, HU; Trauner, M Complementary stimulation of hepatobiliary transport and detoxification by rifampicin and ursodeoxycholic acid in humans - Reply
GASTROENTEROLOGY. 2006; 130: 620-620. Doi: 10.1053/j.gastro.2006.01.019
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Review

** Geier, A; Fickert, P; Trauner, M Mechanisms of disease: mechanisms and clinical implications of cholestasis in sepsis.
Nat Clin Pract Gastroenterol Hepatol. 2006; 3(10): 574-585. Doi: 10.1038/ncpgasthep0602
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** Zollner, G; Marschall, HU; Wagner, M; Trauner, M Role of nuclear receptors in the adaptive response to bile acids and cholestasis: pathogenetic and therapeutic considerations.
Mol Pharm. 2006; 3(3): 231-251. Doi: 10.1021/mp060010s
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** Zollner, G; Trauner, M Molecular mechanisms of cholestasis.
Wien Med Wochenschr. 2006; 156(13-14):380-385 Doi: 10.1007/s10354-006-0312-7
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Abstract (Journal)

** Fauler, G; Stojakovic, T; Putz-Bankuti, C; Gurakuqi, GC; Scharnagl, H; Marz, W; Trauner, M Atorvastatin in patients with primary biliary cirrhosis and an incomplete response to ursodeoxycholic acid
ATHEROSCLER SUPPL. 2006; 7(3):583-583.-XIV. International Symposium on Atherosclerosis; JUNE 18-22, 2006; Rome, Italy. Doi: 10.1016/S1567-5688(06)82367-6 [Poster]
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** Graziadei, IW; Nilica, B; Stadlbauer, V; Stauber, R; Trauner, M; Mueller, C; Vogel, W Imatinib treatment for patients with advanced stage hepatocellular carcinoma: A multicenter phase II trial
HEPATOLOGY. 2006; 44(4):503A-504A. [Poster]
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** Moustafa, T; Fickert, P; Guelly, C; Silbert, D; Gumhold, J; Fuchsbichler, A; Denk, H; Trauner, M Transcriptional profiling of Mdr2 knockout (Mdr2-/-) mice treated with nor-UDCA reveals global anti-inflammatory and anti-fibrotic effects
J HEPATOL. 2006; 44: S42-S42.-41st Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 26-30, 2006; Vienna, AUSTRIA. Doi: 10.1016/S0168-8278(06)80095-4 [Poster]
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** Moustafa, T; Fickert, P; Guelly, C; Silbert, D; Gumhold, J; Fuchsbichler, A; Denk, H; Trauner, M 24-nor-ursodeoxycholic acid abolishes enhanced cellular proliferation in Mdr2 (abcb4) knockout mice by modulation of mTOR, p70s6k and rps6 signaling
HEPATOLOGY. 44(4):602A-603A. [Poster]
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** Moustafa, T; Fickert, P; Prokesch, A; Wagner, M; Fuchsbichler, A; Silbert, D; Gumhold, J; Denk, H; Trajanoski, Z; Trauner, M Common bile-duct-ligation of FXR knockout mice results in severe hepatic steatosis due to enhancement in lipogenic gene expression
J HEPATOL. 44: S28-S28.-41st Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 26-30, 2006; Vienna, AUSTRIA. Doi: 10.1016/S0168-8278(06)80063-2 [Poster]
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** Stoger, U; Fickert, P; Fuchsbichler, A; Moustafa, T; Gumhold, J; Silbert, D; Zatlouka, K; Denk, H; Trauner, M 3.5-diethoxycarbonyl-1.4-dihydrocollidine (DDC) feeding induces cholestasis, chronic inflammatory bile duct damage and biliary fibrosis in mice
J HEPATOL. 44: S123-S124.-41st Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 26-30, 2006; Vienna, AUSTRIA. Doi: 10.1016/S0168-8278(06)80321-1 [Poster]
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** Voigt, S; Martin, IV; Trauner, M; Dietrich, CG; Gartung, C; Trautwein, C; Geier, A Maintained expression of alternative bile salt excretion pathways in inflammatory cholestasis in mice by treatment with class II nuclear hormon receptor ligands
HEPATOLOGY. 44(4):604A-605A. [Poster]
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** Zollner, G; Fuchsbichler, A; Fickert, P; Denk, H; Trauner, M Alterations of hepatic bilirubin and phospholipid export pumps MRP2 and MDR3 in patients with drug-induced liver injury
HEPATOLOGY. 44(4):381A-381A. [Poster]
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** Zollner, G; Wagner, M; Moustafa, T; Fickert, P; Silbert, D; Gumhold, J; Helmut, D; Marschall, HU; Trauner, M Role of nuclear bile acid receptor FXR in regulation of bile acid detoxification and organic solute transporter (OST-alpha/beta) expression in bile acid-fed mice
J HEPATOL. 44: S124-S124.-41st Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 26-30, 2006; Vienna, AUSTRIA. Doi: 10.1016/S0168-8278(06)80322-3 [Poster]
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2005

Full paper/article (Journal)

** Cover, C; Fickert, P; Knight, TR; Fuchsbichler, A; Farhood, A; Trauner, M; Jaeschke, H Pathophysiological role of poly(ADP-ribose) polymerase (PARP) activation during acetaminophen-induced liver cell necrosis in mice.
Toxicol Sci. 2005; 84(1):201-208 Doi: 10.1093/toxsci/kfi065 [OPEN ACCESS]
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** Fickert, P; Trauner, M; Fuchsbichler, A; Zollner, G; Wagner, M; Marschall, HU; Zatloukal, K; Denk, H Oncosis represents the main type of cell death in mouse models of cholestasis.
J Hepatol. 2005; 42(3):378-385 Doi: 10.1016/j.jhep.2004.10.016
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** Geier, A; Dietrich, CG; Voigt, S; Ananthanarayanan, M; Lammert, F; Schmitz, A; Trauner, M; Wasmuth, HE; Boraschi, D; Balasubramaniyan, N; Suchy, FJ; Matern, S; Gartung, C Cytokine-dependent regulation of hepatic organic anion transporter gene transactivators in mouse liver.
Am J Physiol Gastrointest Liver Physiol. 2005; 289(5):G831-G841 Doi: 10.1152/ajpgi.00307.2004 [OPEN ACCESS]
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** Geier, A; Zollner, G; Dietrich, CG; Wagner, M; Fickert, P; Denk, H; van Rooijen, N; Matern, S; Gartung, C; Trauner, M Cytokine-independent repression of rodent Ntcp in obstructive cholestasis.
Hepatology. 2005; 41(3):470-477 Doi: 10.1002/hep.20594 [OPEN ACCESS]
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** Krisper, P; Haditsch, B; Stauber, R; Jung, A; Stadlbauer, V; Trauner, M; Holzer, H; Schneditz, D In vivo quantification of liver dialysis: comparison of albumin dialysis and fractionated plasma separation.
J Hepatol. 2005; 43(3):451-457 Doi: 10.1016/j.jhep.2005.02.038
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** Marschall, HU; Wagner, M; Zollner, G; Fickert, P; Diczfalusy, U; Gumhold, J; Silbert, D; Fuchsbichler, A; Benthin, L; Grundström, R; Gustafsson, U; Sahlin, S; Einarsson, C; Trauner, M Complementary stimulation of hepatobiliary transport and detoxification systems by rifampicin and ursodeoxycholic acid in humans.
Gastroenterology. 2005; 129(2):476-485 Doi: 10.1016/j.gastro.2005.05.009
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** Popov, Y; Patsenker, E; Fickert, P; Trauner, M; Schuppan, D Mdr2 (Abcb4)-/- mice spontaneously develop severe biliary fibrosis via massive dysregulation of pro- and antifibrogenic genes.
J HEPATOL. 2005; 43(6): 1045-1054. Doi: 10.1016/j.jhep.2005.06.025
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** Stadlbauer, V; Fickert, P; Lackner, C; Schmerlaib, J; Krisper, P; Trauner, M; Stauber, RE Hepatotoxicity of NONI juice: report of two cases.
World J Gastroenterol. 2005; 11(30):4758-4760 Doi: 10.3748/wjg.v11.i30.4758 (- Case Report) [OPEN ACCESS]
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** Wagner, M; Halilbasic, E; Marschall, HU; Zollner, G; Fickert, P; Langner, C; Zatloukal, K; Denk, H; Trauner, M CAR and PXR agonists stimulate hepatic bile acid and bilirubin detoxification and elimination pathways in mice.
Hepatology. 2005; 42(2):420-430 Doi: 10.1002/hep.20784 [OPEN ACCESS]
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** Zollner, G; Wagner, M; Fickert, P; Geier, A; Fuchsbichler, A; Silbert, D; Gumhold, J; Zatloukal, K; Kaser, A; Tilg, H; Denk, H; Trauner, M Role of nuclear receptors and hepatocyte-enriched transcription factors for Ntcp repression in biliary obstruction in mouse liver.
Am J Physiol Gastrointest Liver Physiol. 2005; 289(5):G798-G805 Doi: 10.1152/ajpgi.00319.2004 [OPEN ACCESS]
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** Zollner, G; Wagner, M; Fickert, P; Silbert, D; Fuchsbichler, A; Zatloukal, K; Denk, H; Trauner, M Hepatobiliary transporter expression in human hepatocellular carcinoma.
Liver Int. 2005; 25(2):367-379 Doi: 10.1111/j.1478-3231.2005.01033.x
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Review

** Peck-Radosavljevic, M; Trauner, M; Schreiber, F; Austrian Society of Gastroenterology and Hepatology Austrian consensus on the definition and treatment of portal hypertension and its complications.
Endoscopy. 2005; 37(7):667-673 Doi: 10.1055/s-2005-861464
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** Trauner, M; Wagner, M; Fickert, P; Zollner, G Molecular regulation of hepatobiliary transport systems: clinical implications for understanding and treating cholestasis.
J Clin Gastroenterol. 2005; 39(4 Suppl 2):S111-S124 Doi: 10.1097/01.mcg.0000155551.37266.26 [OPEN ACCESS]
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** Wagner, M; Trauner, M Transcriptional regulation of hepatobiliary transport systems in health and disease: implications for a rationale approach to the treatment of intrahepatic cholestasis.
Ann Hepatol. 2005; 4(2): 77-99. Doi: 10.1016/S1665-2681(19)32071-X
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Abstract (Journal)

** Fickert, P; Fuchsbichler, A; Wagner, M; Zollner, G; Krause, R; Zatloukal, K; Marschall, HU; Jaeschke, H; Denk, H; Trauner, M Lithocholic acid feeding induces biliary obstruction and destructive cholangitis in mice
J HEPATOL. 2005; 42: 113-113.-40th Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 13-17, 2005; Paris, FRANCE.
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** Fickert, P; Wagner, M; Marshall, HU; Fuchsbichler, A; Zollner, G; Zatloukal, K; Liu, J; Waalkes, MP; Cover, C; Denk, H; Hofmann, AF; Jaeschke, H; Trauner, M 24-norursodeoxycholic acid as novel therapeutic approach to sclerosing cholangitis in Mdr2 (ABCB4) knockout mice
HEPATOLOGY. 2005; 42: -56th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases; NOV 11-15, 2005; San Francisco, CA.
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** Geier, A; Zollner, G; Dietrich, CG; Wagner, M; Fickert, P; Denk, H; van Rooijen, N; Matern, S; Gartung, C; Trauner, M Cytokine-independent repression of rodent Ntcp in obstructive cholestasis
J HEPATOL. 2005; 42: 114-114.-40th Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 13-17, 2005; Paris, FRANCE.
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** Janig, E; Fuchsbichler, A; Fickert, P; Trauner, M; Denk, H; Zatloukal, K Clusterin: A novel stress marker in biliary disease models
HEPATOLOGY. 2005; 42 (4): 413-414.-56th Annual Meeting of the American Association for the Study of Liver Diseases; NOV 11-15, 2005; San Francisco, CA.
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** Jung, A; Krisper, P; Haditsch, B; Trauner, M; Holzer, H; Schneditz, D Two-compartment model for kinetics of conjugated bilirubin during extracorporeal liver support therapy
NEPHROL DIALYSIS TRANSPLANT. 2005; 20: -42nd Annual Meeting of the European-Renal-Association/European-Dialysis-and-Transplant-Association (ERA-EDTA); JUN 04-07, 2005; Istanbul, TURKEY.
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** Krisper, P; Stadlbauer, V; Haditsch, B; Holzer, H; Trauner, M; Stauber, RE; Schneditz, D The bilirubin/albumin ratio does not influence the clearance of conjugated bilirubin in extracorporeal liver support (ELS)
NEPHROL DIALYSIS TRANSPLANT. 2005; 20: V117-V117.-42nd Annual Meeting of the European-Renal-Association/European-Dialysis-and-Transplant-Association (ERA-EDTA); JUN 04-07, 2005; Istanbul, TURKEY.
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** Marschall, HU; Wagner, M; Zollner, G; Fickert, P; Gumhold, J; Silbert, D; Diczfalusy, U; Benthin, L; Grundstrom, R; Gustafsson, U; Sahlin, S; Einarsson, C; Trauner, M Complementary stimulation of hepatobiliary transport and detoxification systems by rifampicin and ursodeoxycholic acid in human liver
GASTROENTEROLOGY. 2005; 128: A755-A755.
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** Marschall, HU; Wagnr, M; Bodin, K; Zollner, G; Fickert, P; Gumhold, J; Silbert, D; Fuchsbichler, A; Sjovall, J; Trauner, M Fxr -/- mice adapt to obstructive cholestasis by enhanced phase I detoxification and renal elimination of bile acids
J HEPATOL. 2005; 42: 114-115.-40th Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 13-17, 2005; Paris, FRANCE.
Web of Science

 

** Soroka, C; Zollner, G; Mennone, A; Ballatori, N; Trauner, M; Boyer, JL The heteromeric organic solute transporter, Ost alpha-Ost beta, is up-regulated in the liver of patients with primary biliary cirrhosis (PBC) and variably induced in rat and mouse cholangiocytes following bile duct ligation (BDL).
HEPATOLOGY. 2005; 42: -56th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases; NOV 11-15, 2005; San Francisco, CA.
Web of Science

 

** Wagner, M; Zollner, G; Fickert, P; Gumhold, J; Silbert, D; Fuchsbichler, A; Gujral, J; Zatloukal, K; Jaeschke, H; Deck, H; Trauner, M Role of inflammation for hepatobiliary transporter expression in ICAM-/- and lpr mice after common bile duct ligation
GASTROENTEROLOGY. 2005; 128: A89-A89.
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** Wagner, M; Zollner, G; Fickert, P; Gumhold, J; Silbert, D; Fuchsbichler, A; Gujral, JS; Zatloukal, K; Denk, H; Jaeschke, H; Trauner, M Alterations of hepatobiliary transporter expression in response to common bile duct ligation in mice are independent of ICAM-1 and FAS-receptor expression
J HEPATOL. 2005; 42: 115-115.-40th Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 13-17, 2005; Paris, FRANCE.
Web of Science

 

** Zollner, G; Wagner, M; Fickert, P; Gumhold, J; Silbert, D; Marschall, HU; Denk, H; Trauner, M Expression of bile acid synthesis and detoxification enzymes and the alternative bile acid efflux pump MRP4 in patients with primary biliary cirrhosis
GASTROENTEROLOGY. 2005; 128: A691-A691.
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** Zollner, G; Wagner, M; Fickert, P; Gumhold, J; Silbert, D; Marschall, HU; Denk, H; Trauner, M Expression of key bile acid detoxification enzymes and the alternative bile acid export pump MRP4 in primary biliary cirrhosis
J HEPATOL. 2005; 42: 240-240.-40th Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 13-17, 2005; Paris, FRANCE.
Web of Science

 

2004

Full paper/article (Journal)

** Fickert, P; Fuchsbichler, A; Wagner, M; Zollner, G; Kaser, A; Tilg, H; Krause, R; Lammert, F; Langner, C; Zatloukal, K; Marschall, HU; Denk, H; Trauner, M Regurgitation of bile acids from leaky bile ducts causes sclerosing cholangitis in Mdr2 (Abcb4) knockout mice.
Gastroenterology. 2004; 127(1):261-274 Doi: 10.1053/j.gastro.2004.04.009
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** Lammert, F; Wang, DQ; Hillebrandt, S; Geier, A; Fickert, P; Trauner, M; Matern, S; Paigen, B; Carey, MC Spontaneous cholecysto- and hepatolithiasis in Mdr2-/- mice: a model for low phospholipid-associated cholelithiasis.
Hepatology. 2004; 39(1):117-128 Doi: 10.1002/hep.20022 [OPEN ACCESS]
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** Pizarro, M; Balasubramaniyan, N; Solís, N; Solar, A; Duarte, I; Miquel, JF; Suchy, FJ; Trauner, M; Accatino, L; Ananthanarayanan, M; Arrese, M Bile secretory function in the obese Zucker rat: evidence of cholestasis and altered canalicular transport function.
Gut. 2004; 53(12):1837-1843 Doi: 10.1136/gut.2003.037689 [OPEN ACCESS]
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** Trauner, M; Boyer, JL Cholestatic syndromes.
Curr Opin Gastroenterol. 2004; 20(3):220-230 Doi: 10.1097/00001574-200405000-00006
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Short report/Letter

** Stauber, RE; Krisper, P; Zollner, G; Iberer, F; Beuers, U; Trauner, M Extracorporeal albumin dialysis in a patient with primary sclerosing cholangitis: effect on pruritus and bile acid profile.
Int J Artif Organs. 2004; 27(4):342-344 Doi: 10.1177/039139880402700411 (- Case Report)
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** Trauner, M; Fickert, P; Lammert, F; Marschall, HU ABCB4 gene mutations and primary sclerosing cholangitis - Reply
GASTROENTEROLOGY. 2004; 126: 1222-1223. Doi: 10.1053/j.gastro.2004.02.043
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Review

** Zatloukal, K; Stumptner, C; Fuchsbichler, A; Fickert, P; Lackner, C; Trauner, M; Denk, H The keratin cytoskeleton in liver diseases.
J Pathol. 2004; 204(4):367-376 Doi: 10.1002/path.1649 [OPEN ACCESS]
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Abstract (Journal)

** Fickert, P; Fuchsbichler, A; Wagner, M; Zollner, G; Kaser, A; Tilg, H; Krause, R; Langner, C; Zatloukal, K; Marschall, HU; Denk, H; Trauner, M Biliary leakage of fluorescent bile acids in MDR2 knockout mice: Evidence for a critical role of bile duct leakage in the pathogenesis of sclerosing cholangitis
J HEPATOL. 2004; 40: 91-91.-39th Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 14-18, 2004; Berlin, GERMANY. Doi: 10.1016/S0168-8278(04)90295-4
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** Fickert, P; Fuchsbichler, A; Wagner, M; Zollner, G; Kaser, A; Tilg, H; Krause, R; Langner, C; Zatloukal, K; Marschall, HU; Denk, H; Trauner, M Bile acids regurgitation from leaky bile ducts causes sclerosing cholangitis in Mdr2 knockout mice
GASTROENTEROLOGY. 2004; 126: A663-A663.
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** Fickert, P; Trauner, M; Fuchsbichler, A; Zollner, G; Wagner, M; Marschall, HU; Zartloukal, K; Denk, H; Zsengeller, Z; Szabo, C Oncosis represents the main type of cell death in mouse models of cholestasis: evidence for a critical role of poly(ADP-ribose) polymerase (PARP) activation in bile acid-induced hepatocytes death
FASEB J. 2004; 18: A558-A558.-Experimental Biology 2004 Meeting; APR 17-21, 2004; Washington, DC.
Web of Science

 

** Hofer, H; Szalay, F; Lakatos, P; Oesterreicher, C; Willheim-Polli, C; Pirker, A; Trauner, M; Datz, C; Gschwantler, M; Habior, A; Penner, E; Ferenci, P NOD2/CARD15 mutations in patients with primary biliary cirrhosis.
HEPATOLOGY. 2004; 40: 465A-465A.-55th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD); OCT 29-NOV 02, 2004; Boston, MA.
Web of Science

 

** Knight, T; Fickert, P; Fuchsbichler, A; Trauner, M; Jaeschke, H Pathophysiological role of poly(adenosine 5'-diphosphate-ribose) polymerase (PARP) activation during acetaminophen-induced liver cell necrosis in mice.
HEPATOLOGY. 2004; 40: 650A-650A.-55th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD); OCT 29-NOV 02, 2004; Boston, MA.
Web of Science

 

** Krisper, P; Stauber, R; Haditsch, B; Trauner, M; Holzer, H; Schneditz, D MARS versus Prometheus: Comparison of clearances as a measure of efficiency in two different liver detoxification devices
GASTROENTEROLOGY. 2004; 126: A706 -A706 .
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** Krisper, P; Stauber, R; Haditsch, B; Trauner, M; Holzer, H; Schneditz, D Mars versus prometheus: Comparison of reduction ratios (RR) as a measure of treatment dose in two different liver detoxification devices
J HEPATOL. 2004; 40: 69-70.-39th Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 14-18, 2004; Berlin, GERMANY. Doi: 10.1016/S0168-8278(04)90216-4
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** Marschall, HU; Wagner, M; Zollner, G; Fickert, P; Gumhold, J; Silbert, D; Diczfalusy, U; Benthin, L; Grundstrom, R; Sahlin, S; Einarsson, C; Trauner, M Comprehensive study of the effects of rifampicin and ursodeoxycholic acid on genes and proteins involved in regulation, transport and detoxification of biliary compounds in gallstone patients
GASTROENTEROLOGY. 2004; 126: A746-A746.
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** Marschall, HU; Wagner, M; Zollner, G; Fickert, P; Gumholdt, J; Silbert, D; Diczfalusy, U; Benthin, L; Grundstrom, R; Sahlin, S; Einarsson, C; Trauner, M Comprehensive study of the effects of rifampicin and ursodeoxycholic acid on genes and proteins involved in regulation, transport and detoxification of biliary compounds in gallstone patients
J HEPATOL. 2004; 40: 93-93.-39th Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 14-18, 2004; Berlin, GERMANY. Doi: 10.1016/S0168-8278(04)90303-0
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** Popov, Y; Patsenker, E; Trauner, M; Schuppan, D MDR-2 KO mice develop rapid biliary fibrosis via massive up-regultion of procollagen I and TIMP-1 expression.
HEPATOLOGY. 2004; 40: 463A-463A.-55th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD); OCT 29-NOV 02, 2004; Boston, MA.
Web of Science

 

** Rudolph, CM; Trauner, M; Kerl, H; Mullegger, RR Pruritic skin conditions during pregnancy: Serum bile acid levels are a highly reliable parameter to diagnose intrahepatic cholestasis of pregnancy (ICP)
J INVEST DERMATOL. 2004; 123:
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** Wagner, M; Fickert, P; Marschall, HU; Zollner, G; Silbert, D; Fuchsbichler, A; Gumhold, J; Schuetz, JD; Gonzalez, FJ; Zatloukal, K; Denk, H; Trauner, M Alternative exretory routes for accumulating bile acids via adaptive renal ABC transporter expression in common bile duct-ligated (CBDL) mice
GASTROENTEROLOGY. 2004; 126: A129-A130.
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** Wagner, M; Fickert, P; Zollner, G; Fuchsbichler, A; Gumhold, J; Silbert, D; Zatloukal, K; Gu, GL; Marschall, HU; Denk, H; Trauner, M Role of adaptive hepatobiliary transporter expression and regulation of bile acid synthetic enzymes in MDR2-/- mice: A model for chronic cholestatic liver disease due to sclerosing cholangitis
J HEPATOL. 2004; 40: 163-163.-39th Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 14-18, 2004; Berlin, GERMANY. Doi: 10.1016/S0168-8278(04)90557-0
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** Wagner, M; Fickert, P; Zollner, G; Silbert, D; Fuchsbichler, A; Gumhold, J; Schuetz, JD; Gonzalez, FJ; Zatloukal, K; Marschall, HU; Denk, H; Trauner, M Adaptive renal ABC transporter expression in common bile duct-ligated mice
J HEPATOL. 2004; 40: 26-26.-39th Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 14-18, 2004; Berlin, GERMANY. Doi: 10.1016/S0168-8278(04)90073-6
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** Wagner, M; Fickert, P; Zollner, G; Silbert, D; Gumhold, J; Fuchsbichler, A; Zatloukal, K; Marschall, HU; Denk, H; Trauner, M Hepatic and renal ABC transporter expression in mice depends on gender and changes in pregnancy
GASTROENTEROLOGY. 2004; 126: A130-A130.
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** Wagner, M; Fickert, P; Zollner, G; Silbert, D; Gumhold, J; Fuchsbichler, A; Zatloukal, K; Marschall, HU; Denk, H; Trauner, M Gender and pregnancy affect hepatic and renal ABC transporter expression in mice
J HEPATOL. 2004; 40: 94-94.-39th Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 14-18, 2004; Berlin, GERMANY. Doi: 10.1016/S0168-8278(04)90307-8
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** Wagner, M; Halilbasic, E; Fickert, P; Zollner, G; Fuchsbichler, A; Gumhold, J; Silbert, D; Zatloukal, K; Denk, H; Trauner, M Nuclear receptor (PXR, CAR) agonists induce adaptive hepatic transporter and enzyme expression in mouse liver
J HEPATOL. 2004; 40: 25-25.-39th Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 14-18, 2004; Berlin, GERMANY. Doi: 10.1016/S0168-8278(04)90069-4
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** Wagner, M; Halilbasic, E; Zollner, G; Fickert, P; Gumhold, J; Silbert, D; Fuchsbichler, A; Zatloukal, K; Denk, H; Trauner, M Xenobiotic nuclear receptor (PXR, CAR) agonists coordinately stimulate a spectrum of detoxification enzymes and transport systems involved in the adaptive response to cholestasis in vivo.
HEPATOLOGY. 2004; 40: 489A-489A.-55th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD); OCT 29-NOV 02, 2004; Boston, MA.
Web of Science

 

** Zollner, G; Halilbasic, E; Wagner, M; Fickert, P; Silbert, D; Gumhold, J; Fuchsbichler, A; Zatloukal, K; Denk, H; Trauner, M Differential effects of ursodeoxycholic acid (UDCA) and cholic acid (CA) on hepatic and renal expression of MRP4 and MRP6, two novel abc transporters, in mice
J HEPATOL. 2004; 40: 25-25. Doi: 10.1016/S0168-8278(04)90070-0
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** Zollner, G; Halilbasic, E; Wagner, M; Fickert, P; Silbert, D; Gumhold, J; Fuchsbichler, A; Zatloukal, K; Denk, H; Trauner, M Cholic acid (CA) and ursodeoxycholic acid (UDCA) exert different effects on hepatic and renal expression of Mrp4 and Mrp6, two novel ABC transporters
GASTROENTEROLOGY. 2004; 126: A16-A16.
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** Zollner, G; Wagner, M; Fickert, P; Fuchsbichler, A; Gumhold, J; Silbert, D; Zatloukal, K; Guo, GL; Marschall, HU; Denk, H; Trauner, M Mdr2(-/-) mice with sclerosing cholangitis: A model of chronic cholestasis to study the role of the adaptive response of hepatobiliary transport systems and bile acid synthetic enzymes
GASTROENTEROLOGY. 2004; 126: A751-A751.
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Comment

** Trauner, M The nuclear bile acid receptor FXR as a novel therapeutic target in cholestatic liver diseases: hype or hope?
Hepatology. 2004; 40(1):260-263 Doi: 10.1002/hep.20294 [OPEN ACCESS]
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2003

Full paper/article (Journal)

** Arrese, M; Trauner, M Molecular aspects of bile formation and cholestasis.
Trends Mol Med. 2003; 9(12):558-564 Doi: 10.1016/j.molmed.2003.10.002
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** Arrese, M; Trauner, M; Ananthanarayanan, M; Pizarro, M; Solís, N; Accatino, L; Soroka, C; Boyer, JL; Karpen, SJ; Miquel, JF; Suchy, FJ Down-regulation of the Na+/taurocholate cotransporting polypeptide during pregnancy in the rat.
J Hepatol. 2003; 38(2):148-155 Doi: 10.1016/S0168-8278(02)00379-3
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** Fickert, P; Trauner, M; Fuchsbichler, A; Stumptner, C; Zatloukal, K; Denk, H Mallory body formation in primary biliary cirrhosis is associated with increased amounts and abnormal phosphorylation and ubiquitination of cytokeratins.
J Hepatol. 2003; 38(4):387-394 Doi: 10.1016/S0168-8278(02)00439-7
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** Trauner, M; Boyer, JL Cholestatic syndromes.
Curr Opin Gastroenterol. 2003; 19(3):216-231 Doi: 10.1097/00001574-200305000-00005
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** Wagner, M; Fickert, P; Zollner, G; Fuchsbichler, A; Silbert, D; Tsybrovskyy, O; Zatloukal, K; Guo, GL; Schuetz, JD; Gonzalez, FJ; Marschall, HU; Denk, H; Trauner, M Role of farnesoid X receptor in determining hepatic ABC transporter expression and liver injury in bile duct-ligated mice.
Gastroenterology. 2003; 125(3):825-838 Doi: 10.1016/S0016-5085(03)01068-0
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** Wagner, M; Kaufmann, P; Fickert, P; Trauner, M; Lackner, C; Stauber, RE Successful conservative management of acute hepatic failure following exertional heatstroke.
Eur J Gastroenterol Hepatol. 2003; 15(10):1135-1139 Doi: 10.1097/01.meg.0000085465.12407.32 (- Case Report)
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** Zollner, G; Fickert, P; Fuchsbichler, A; Silbert, D; Wagner, M; Arbeiter, S; Gonzalez, FJ; Marschall, HU; Zatloukal, K; Denk, H; Trauner, M Role of nuclear bile acid receptor, FXR, in adaptive ABC transporter regulation by cholic and ursodeoxycholic acid in mouse liver, kidney and intestine.
J Hepatol. 2003; 39(4):480-488 Doi: 10.1016/S0168-8278(03)00228-9
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** Zollner, G; Fickert, P; Silbert, D; Fuchsbichler, A; Marschall, HU; Zatloukal, K; Denk, H; Trauner, M Adaptive changes in hepatobiliary transporter expression in primary biliary cirrhosis.
J Hepatol. 2003; 38(6):717-727 Doi: 10.1016/S0168-8278(03)00096-5
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Review

** Trauner, M; Boyer, JL Bile salt transporters: molecular characterization, function, and regulation.
Physiol Rev. 2003; 83(2):633-671 Doi: 10.1152/physrev.00027.2002 [OPEN ACCESS]
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Abstract (Journal)

** Fickert, P; Trauner, M; Fuchsbichler, A; Zollner, G; Wagner, M; Zenz, R; Zsengeller, Z; Szabo, C; Denk, H Inhibition of poly(ADP-ribose) polymerase (PARP) protects mice from cholestatic liver injury.
HEPATOLOGY 2003 38: 576A-576A.
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** Wagner, M; Fickert, P; Fuchsbichler, A; Silbert, D; Gumhold, J; Zollner, G; Zatloukal, K; Marschall, HU; Schuetz, JD; Gonzalez, FJ; Denk, H; Trauner, M Hepatic and renal ABC transporter expression as critical determinants of ursodeoxycholic acid-induced bile infarcts in bile duct-ligated mice.
HEPATOLOGY 2003 38: 688A-689A.
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** Wagner, M; Fickert, P; Zollner, G; Fuchsbichler, A; Silbert, D; Marschall, HU; Gonzalez, FJ; Zatloukal, K; Denk, H; Trauner, M The role of the bile acid receptor FXR in determining ATP-binding cassette (ABC) transporter expression and liver injury in common bile duct ligated (CBDL) mice
J HEPATOL 2003 38: 190-190. Doi: 10.1016/S0168-8278(03)80031-4
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** Wagner, M; Fickert, P; Zollner, G; Fuchsbichler, A; Silbert, D; Tsybrovskyy, O; Gonzalez, FJ; Zatloukal, K; Marschall, HU; Denk, H; Trauner, M Role of nuclear bile acid receptor, FXR, in determining ATP-binding cassette (ABC) transporter expression and cholestatic liver injury in common bile duct-ligated mice
GASTROENTEROLOGY 2003 124: A697-A698. Doi: 10.1016/S0016-5085(03)83527-8
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** Zatloukal, K; Stumptner, C; Fuchsbichler, A; Fickert, P; Trauner, M; Denk, H The role of keratin in steatohepatitis.
HEPATOLOGY 2003 38: 501A-501A.
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** Zollner, G; Fickert, P; Silbert, D; Fuchsbichler, A; Wagner, M; Guo, G; Gonzalez, FJ; Zatloukal, K; Denk, H; Trauner, M Role of nuclear bile salt receptors Fxr and Pxr in mediating adaptive hepatobiliary transporter response to cholic acid (CA) in mouse liver
GASTROENTEROLOGY 2003 124: A59-A59. Doi: 10.1016/S0016-5085(03)80292-5
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** Zollner, G; Fickert, P; Silbert, D; Fuchsbichler, A; Wagner, M; Zatloukal, K; Denk, H; Trauner, M Regulation of the Na+/taurocholate cotransporter Ntcp via short heterodimer partner (SHP)-dependent or SHP-independent mechanims depends on the type of cholestatic injury
GASTROENTEROLOGY 2003 124: A730-A730. Doi: 10.1016/S0016-5085(03)83688-0
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** Zollner, G; Fickert, P; Silbert, D; Fuchsbichler, A; Wagner, M; Zatloukal, K; Denk, H; Trauner, M Role of short heterodimer partner (SHP) -dependent and -independent pathways for regulation of Na+/taurocholate cotransporter (NTCP) expression in cholestatic mouse models.
J HEPATOL. 2003; 38(2):9-10.-38th Annual Meeting of the European-Association-for-the-Study-of-the-Liver; MAR 29-APR 01, 2003; ISTANBUL, TURKEY. Doi: 10.1016/S0168-8278(03)80442-7
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** Zollner, G; Fickert, P; Wagner, M; Fuchsbichler, A; Silbert, D; Gumhold, J; Zatloukal, K; Denk, H; Trauner, M Induction of intestinal multidrug resistance-associated proteins 2 and 3 (Mrp2, Mrp3) by cholic acid (CA) and ursodeoxycholic acid (UDCA) in mice.
HEPATOLOGY 2003 38: 689A-689A.
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Comment

** Marschall, HU; Trauner, M; Lammert, F Jaundice.
Scand J Gastroenterol. 2003; 38(3):233-234 Doi: 10.1080/00365520310000573
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** Tilg, H; Jalan, R; Kaser, A; Davies, NA; Offner, FA; Hodges, SJ; Ludwiczek, O; Shawcross, D; Zoller, H; Alisa, A; Mookerjee, RP; Graziadei, I; Datz, C; Trauner, M; Schuppan, D; Obrist, P; Vogel, W; Williams, R Anti-tumor necrosis factor-alpha monoclonal antibody therapy in severe alcoholic hepatitis.
J Hepatol. 2003; 38(4):419-425 Doi: 10.1016/S0168-8278(02)00442-7
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** Trauner, M When bile ducts say NO: the good, the bad, and the ugly.
Gastroenterology. 2003; 124(3):847-851 Doi: 10.1053/gast.2003.50122
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2002

Full paper/article (Journal)

** Fickert, P; Trauner, M; Fuchsbichler, A; Stumptner, C; Zatloukal, K; Denk, H Cytokeratins as targets for bile acid-induced toxicity.
Am J Pathol. 2002; 160(2):491-499 Doi: 10.1016/S0002-9440(10)64868-7 [OPEN ACCESS]
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** Fickert, P; Trauner, M; Fuchsbichler, A; Stumptner, C; Zatloukal, K; Denk, H Bile acid-induced Mallory body formation in drug-primed mouse liver.
Am J Pathol. 2002; 161(6):2019-2026 Doi: 10.1016/S0002-9440(10)64480-X [OPEN ACCESS]
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** Fickert, P; Zollner, G; Fuchsbichler, A; Stumptner, C; Weiglein, AH; Lammert, F; Marschall, HU; Tsybrovskyy, O; Zatloukal, K; Denk, H; Trauner, M Ursodeoxycholic acid aggravates bile infarcts in bile duct-ligated and Mdr2 knockout mice via disruption of cholangioles.
Gastroenterology. 2002; 123(4):1238-1251 Doi: 10.1053/gast.2002.35948
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** Trauner, M; Boyer, JL Cholestatic syndromes.
Curr Opin Gastroenterol. 2002; 18(3):314-329 Doi: 10.1097/00001574-200205000-00005
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** Zollner, G; Fickert, P; Silbert, D; Fuchsbichler, A; Stumptner, C; Zatloukal, K; Denk, H; Trauner, M Induction of short heterodimer partner 1 precedes downregulation of Ntcp in bile duct-ligated mice.
Am J Physiol Gastrointest Liver Physiol. 2002; 282(1):G184-G191 Doi: 10.1152/ajpgi.00215.2001 [OPEN ACCESS]
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Short report/Letter

** Hegenbarth, K; Fickert, P; Aschauer, M; Horina, JH; Stauber, RE; Trauner, M Successful management of acute portal vein thrombosis by low molecular weight heparin and oral anticoagulation.
Am J Gastroenterol. 2002; 97(6):1567-1568 Doi: 10.1111/j.1572-0241.2002.05750.x (- Case Report)
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Review

** Ferenci, P; Zollner, G; Trauner, M Hepatic transport systems.
J Gastroenterol Hepatol. 2002; 17 Suppl(6):S105-S112 Doi: 10.1046/j.1440-1746.17.s1.15.x
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Abstract (Journal)

** Fickert, P; Trauner, M; Fuchsbichler, A; Stumptner, C; Neuberger, J; Zatloukal, K; Denk, H Abnormal expression and phosphorylation of cytokeratins in primary biliary cirrhosis (PBC).
J HEPATOL. 2002; 36(S1):141-141. Doi: 10.1016/S0168-8278(02)80506-2
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** Fickert, P; Zollner, G; Silbert, D; Fuchsbichler, A; Arbeiter, S; Gonzalez, F; Denk, H; Trauner, M Adaptive hepatic and renal transporter regulation in cholic acid (CA)-fed mice: Role of nuclear bile acid receptor (FXR).
HEPATOLOGY 2002 36: 454A-454A.
Web of Science

 

** Zollner, G; Fickert, P; Arbeiter, S; Silbert, D; Fuchsbichler, A; Gonzalez, F; Zatloukal, K; Denk, H; Trauner, M Ursodeoxycholic acid (UDCA) feeding induces adaptive hepatic and renal ABC-transporter expression in mice.
HEPATOLOGY 2002 36: 454A-454A.
Web of Science

 

** Zollner, G; Fickert, P; Silbert, D; Fuchsbichler, A; Stumptner, C; Neuberger, J; Zatloukal, K; Denk, H; Trauner, M Alterations of hepatobiliary transporter expression in primary biliary cirrhosis (PBC)
J HEPATOL 2002 36: 28-29. Doi: 10.1016/S0168-8278(02)80086-1
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** Zollner, G; Fickert, P; Silbert, D; Fuchsbichler, A; Zatloukal, K; Denk, H; Trauner, M Messenger RNA expression of nuclear, orphan receptors and hepatocyte nuclear factor 1 alpha (HNF-1 alpha) in inflammation-associated cholestasis (IC) and primary biliary cirrhosis
HEPATOLOGY 2002 36: 454A-454A.
Web of Science

 

2001

Full paper/article (Journal)

** Fickert, P; Zollner, G; Fuchsbichler, A; Stumptner, C; Pojer, C; Zenz, R; Lammert, F; Stieger, B; Meier, PJ; Zatloukal, K; Denk, H; Trauner, M Effects of ursodeoxycholic and cholic acid feeding on hepatocellular transporter expression in mouse liver.
Gastroenterology. 2001; 121(1):170-183 Doi: 10.1053/gast.2001.25542
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** Langner, C; Thonhofer, R; Hegenbarth, K; Trauner, M Diffuse hemangiomatosis of the liver and spleen in an adult.
Pathologe. 2001; 22(6):424-428 Doi: 10.1007/s002920100491 (- Case Report)
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** Trauner, M; Boyer, JL Cholestatic syndromes.
Curr Opin Gastroenterol. 2001; 17(3):242-256 Doi: 10.1097/00001574-200105000-00007
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** Zollner, G; Fickert, P; Zenz, R; Fuchsbichler, A; Stumptner, C; Kenner, L; Ferenci, P; Stauber, RE; Krejs, GJ; Denk, H; Zatloukal, K; Trauner, M Hepatobiliary transporter expression in percutaneous liver biopsies of patients with cholestatic liver diseases.
Hepatology. 2001; 33(3):633-646 Doi: 10.1053/jhep.2001.22646 [OPEN ACCESS]
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Short report/Letter

** Hegenbarth, K; Maurer, U; Kroisel, PM; Fickert, P; Trauner, M; Stauber, RE No evidence for mutagenic effects of ribavirin: report of two normal pregnancies.
Am J Gastroenterol. 2001; 96(7):2286-2287 Doi: 10.1111/j.1572-0241.2001.03997.x (- Case Report)
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Review

** Trauner, M; Fickert, P; Zollner, G Genetic disorders and molecular mechanisms in cholestatic liver disease--a clinical approach.
Semin Gastrointest Dis. 2001; 12(2):66-88 (- Case Report)
PubMed Google Scholar

 

Abstract (Journal)

** Fickert, P; Fuchsbichler, A; Zollner, G; Stumptner, C; Weiglein, A; Zatloukal, K; Denk, H; Trauner, M Mdr2-p-glycoprotein-deficient (Mdr2-/-) mouse - A new model for primary sclerosing cholangitis (PSC)?
HEPATOLOGY 2001 34: 509A-509A.
Web of Science

 

** Fickert, P; Zollner, G; Fuchsbichler, A; Stumptner, C; Lammert, F; Zaltloukal, K; Denk, H; Trauner, M Ursodeoxycholic acid (UDCA) feeding aggravates liver injury in bile duct-ligated and Mdr2 kockout mice
J HEPATOL 2001 34: 182-182.
Web of Science

 

** Fickert, P; Zollner, G; Fuchsbichler, A; Stumptner, C; Lammert, F; Zatloukal, K; Denk, H; Trauner, M Ursodeoxycholic acid feeding aggravates liver injury in bile duct-ligated mice
GASTROENTEROLOGY 2001 120: A1-A1.
Web of Science

 

** Zollner, G; Fickert, P; Fuchsbichler, A; Stumptner, C; Denk, H; Zatloukal, K; Ferenci, P; Trauner, M Expression of multidrug resistance P-glycoproteins (MDRs) and multidrug resistance-associated proteins (MRPs) in Wilson disease (WD)
J HEPATOL 2001 34: 188-188.
Web of Science

 

** Zollner, G; Fickert, P; Fuchsbichler, A; Stumptner, C; Denk, H; Zatloukal, K; Trauner, M Multidrug resistance P-glycoproteins (MDR) and multidrug resistance-associated proteins (MRP) are not overexpressed in human hepatocellular carcinomas (HCC).
J HEPATOL 2001 34: 189-189.
Web of Science

 

** Zollner, G; Fickert, P; Silbert, D; Fuchsbichler, A; Stumptner, C; Ott, P; Zatloukal, K; Denk, H; Trauner, M Expression of multidrug resistance p-glycoproteins (MDR), multidrug resistance-associated proteins (MRP) and bile acid transporters in human hepatocellular carcinomas (HCC).
HEPATOLOGY 2001 34: 665A-665A.
Web of Science

 

** Zollner, G; Fickert, P; Silbert, D; Fuchsbichler, A; Zatloukal, K; Denk, H; Trauner, M; Franzens, K Induction of the transcriptional repressor short heterodimer partner 1 precedes down-regulation of the Na+/taurocholate cotransporter in bile duct-ligated mice.
HEPATOLOGY 2001 34: 469A-469A.
Web of Science

 

Comment

** Trauner, M; Fickert, P; Zollner, G Abnormal hepatic sinusoidal bile acid transport: new insights into the pathogenesis of cholestasis?
Gastroenterology. 2001; 120(1):321-323 Doi: 10.1053/gast.2001.21380
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2000

Full paper/article (Journal)

** Fickert, P; Trauner, M; Hausegger, K; Tauss, J; Lackner, H; Krejs, GJ; Stauber, RE Intra-hepatic haematoma complicating transjugular intra-hepatic portosystemic shunt for Budd-Chiari syndrome associated with anti-phospholipid antibodies, aplastic anaemia and chronic hepatitis C.
Eur J Gastroenterol Hepatol. 2000; 12(7):813-816 Doi: 10.1097/00042737-200012070-00017 (- Case Report)
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** Lee, JM; Trauner, M; Soroka, CJ; Stieger, B; Meier, PJ; Boyer, JL Expression of the bile salt export pump is maintained after chronic cholestasis in the rat.
Gastroenterology. 2000; 118(1):163-172 Doi: 10.1016/S0016-5085(00)70425-2
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** Trauner, M; Boyer, JL Cholestatic syndromes.
Curr Opin Gastroenterol. 2000; 16(3):239-250 Doi: 10.1097/00001574-200005000-00006
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Review

** Trauner, M; Fickert, P; Stauber, RE Hepatocellular bile salt transport: lessons from cholestasis.
Can J Gastroenterol. 2000; 14 Suppl D(3):99D-104 Doi: 10.1155/2000/870929
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Abstract (Journal)

** Fickert, P; Trauner, M; Fuchsbichler, A; Zatloukal, K; Denk, H Toxic bile acids induce cytokeratin 8/18 overexpression and hyperphosphorylation in mouse liver.
GASTROENTEROLOGY 2000 118: 3726-3726. Doi: 10.1016/S0016-5085(00)86223-X
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** Fickert, P; Trauner, M; Fuchsbichler, A; Zatloukal, K; Denk, H Cytokeratin 8/18 overexpression and hyperphosphorylation induced by toxic bile acids in mouse liver
J HEPATOL 2000 32: 76-76. Doi: 10.1016/S0168-8278(00)80623-6
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** Fickert, P; Zenz, R; Zoliner, G; Pojer, C; Fuchsbichler, A; Zatloukal, K; Denk, H; Trauner, M Role of bile acid hydrophobicity in regulation of hepatocellular transporter expression in mice
J HEPATOL. 2000; 32(1 Su):39-39. Doi: 10.1016/S0168-8278(00)80479-1
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** Fickert, P; Zenz, R; Zollner, G; Pojer, C; Fuchsbichler, A; Zatloukal, K; Denk, H; Trauner, M Regulation of hepatocellular transporter expression depends on bile acid hydrophobicity in mice.
GASTROENTEROLOGY 2000 118: 168-168. Doi: 10.1016/S0016-5085(00)85876-X
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** Schreiber, F; Eherer, AJ; Trauner, M; Schnedl, W; Gurakuqi, GC; Krojs, GJ Self expanding metallic stents in malignant enteral obstruction - Early experiences with a new palliative treatment.
GASTROINTEST ENDOSCOP 2000 51: 3496-3496. Doi: 10.1016/S0016-5107(00)14196-3
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** Stauber, RE; Hegenbarth, KS; Maurer, U; Kroisel, PM; Fickert, P; Trauner, M No evidence for teratogenic effects of ribavirin: Report of two cases.
HEPATOLOGY 2000 32: 1639-1639.
Web of Science

 

1999

Full paper/article (Journal)

** Trauner, M; Boyer, JL Cholestatic syndromes.
Curr Opin Gastroenterol. 1999; 15(3):217-228 Doi: 10.1097/00001574-199905000-00006
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Review

** Trauner, M; Boyer, JL Cholestatic syndromes
CURR OPIN GASTROEN. 1999; 15(3): 217-228. Doi: 10.1097/00001574-199905000-00006
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** Trauner, M; Fickert, P; Stauber, RE Inflammation-induced cholestasis.
J Gastroenterol Hepatol. 1999; 14(10):946-959 Doi: 10.1046/j.1440-1746.1999.01982.x [OPEN ACCESS]
Web of Science PubMed FullText FullText_MUG

 

** Trauner, M; Fickert, P; Stauber, RE New molecular aspects of cholestatic liver diseases.
Z Gastroenterol. 1999; 37(7):639-647
Web of Science PubMed

 

** Trauner, M; Graziadei, IW Review article: mechanisms of action and therapeutic applications of ursodeoxycholic acid in chronic liver diseases.
Aliment Pharmacol Ther. 1999; 13(8):979-996 Doi: 10.1046/j.1365-2036.1999.00596.x [OPEN ACCESS]
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** Trauner, M; Meier, PJ; Boyer, JL Molecular regulation of hepatocellular transport systems in cholestasis.
J Hepatol. 1999; 31(1):165-178 Doi: 10.1016/S0168-8278(99)80179-2
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Abstract (Journal)

** Fickert, P; Trauner, M; Fuchsbichler, A; Kenner, L; Zatloukal, K; Denk, H Role of Kupffer cells in hepatocellular cytokeratin 8/18 expression in lipopoly-saccharide or DDC-induced hepatic injury.
HEPATOLOGY 1999 30: 552A-552A.
Web of Science

 

** Fickert, P; Trauner, M; Fuchsbichler, A; Zatloukal, K; Denk, H Cholestasis and bile acid feeding induce cytokeratin 8/18 expression and mallory body formation in mice.
HEPATOLOGY 1999 30: 464A-464A.
Web of Science

 

** Trauner, M; Fickert, F; Zenz, R; Pojer, C; Fuchsbichler, A; Zollner, G; Denk, H; Zatloukal, K Role of Kupffer cells in regulation of multidrug resistance (mdr) P-glycoprotein expression in intrahepatic and obstructive cholestasis.
HEPATOLOGY 1999 30: 463A-463A.
Web of Science

 

** Trauner, M; Zenz, R; Fickert, P; Kenner, L; Stauber, RE; Denk, H; Zatloukal, K Quantification of hepatobiliary transporter expression in liver biopsies from patients with cholestasis.
HEPATOLOGY 1999 30: 467A-467A.
Web of Science

 

1998

Full paper/article (Journal)

** Arrese, M; Trauner, M; Ananthanarayanan, M; Boyer, JL; Suchy, FJ Maternal cholestasis does not affect the ontogenic pattern of expression of the Na+/taurocholate cotransporting polypeptide (ntcp) in the fetal and neonatal rat liver.
Hepatology. 1998; 28(3):789-795 Doi: 10.1002/hep.510280328 [OPEN ACCESS]
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** Arrese, M; Trauner, M; Sacchiero, RJ; Crossman, MW; Shneider, BL Neither intestinal sequestration of bile acids nor common bile duct ligation modulate the expression and function of the rat ileal bile acid transporter.
Hepatology. 1998; 28(4):1081-1087 Doi: 10.1002/hep.510280424 [OPEN ACCESS]
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** Fickert, P; Trauner, M; Sill, H; Hinterleitner, TA; Stauber, RE Successful steroid treatment of idiopathic thrombocytopenic purpura after orthotopic liver transplantation for primary biliary cirrhosis.
Am J Gastroenterol. 1998; 93(10):1985-1986 Doi: 10.1111/j.1572-0241.1998.00561.x (- Case Report)
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** Heinemann, A; Wachter, CH; Fickert, P; Trauner, M; Stauber, RE Vasopressin reverses mesenteric hyperemia and vasoconstrictor hyporesponsiveness in anesthetized portal hypertensive rats.
Hepatology. 1998; 28(3):646-654 Doi: 10.1002/hep.510280307 [OPEN ACCESS]
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** Koeppel, TA; Trauner, M; Mennone, A; Arrese, M; Rios-Velez, L; Boyer, JL Role of glutathione in hepatic bile formation during reperfusion after cold ischemia of the rat liver.
J Hepatol. 1998; 28(5):812-819 Doi: 10.1016/S0168-8278(98)80231-6
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** Trauner, M; Arrese, M; Lee, H; Boyer, JL; Karpen, SJ Endotoxin downregulates rat hepatic ntcp gene expression via decreased activity of critical transcription factors.
J Clin Invest. 1998; 101(10):2092-2100 Doi: 10.1172/JCI1680 [OPEN ACCESS]
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** Trauner, M; Mennone, A; Gigliozzi, A; Fraioli, F; Boyer, JL Nitric oxide and guanosine 3',5'-cyclic monophosphate stimulate bile secretion in isolated rat hepatocyte couplets, but not in isolated bile duct units.
Hepatology. 1998; 28(6):1621-1628 Doi: 10.1002/hep.510280623 [OPEN ACCESS]
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Review

** Trauner, M; Meier, PJ; Boyer, JL Molecular pathogenesis of cholestasis.
N Engl J Med. 1998; 339(17):1217-1227 Doi: 10.1056/NEJM199810223391707 [OPEN ACCESS]
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Abstract (Journal)

** Kenner, L; Stumptner, C; Trauner, M; Fickert, P; Stauber, RE; Eferl, R; Denk, H; Zatloukal, K Tau overexpression in human alcoholic liver disease.
HEPATOLOGY 1998 28: 512A-512A.
Web of Science

 

** Kenner, L; Trauner, M; Fickert, P; Stauber, RE; Eferl, R; Denk, H; Zatloukal, K Overexpression of keratin-8 and -18 RNA associated with mallory body formation in patients with alcoholic hepatitis.
HEPATOLOGY 1998 28: 303A-303A.
Web of Science

 

** Lee, JM; Trauner, M; Soroka, CJ; Steiger, B; Meier, PJ; Boyer, JL The molecular expression of the bile salt excretory pump, sister of P-glycoprotein (spgp), is selectively preserved in cholestatic liver injury.
HEPATOLOGY 1998 28: 429A-429A.
Web of Science

 

** Schreiber, F; Gurakuqi, GCH; Trauner, M; Schnedl, W; Krejs, GJ Self expanding metallic stents in malignant colonic obstruction - Early experiences with a new palliative treatment
GASTROINTEST ENDOSCOP 1998 47: AB104-AB104.
Web of Science

 

** Stauber, RE; Trauner, M; Fickert, P Soreness of mucosal membranes in patients receiving interferon-alpha plus ribavirin for treatment of chronic hepatitis C.
HEPATOLOGY 1998 28: 704A-704A.
Web of Science

 

** Trauner, M; Mennone, A; Gigliozzi, A; Fraioli, F; Boyer, JL Nitric oxide (NO) and guanosine 3 ',5 '-cyclic monophosphate (cGMP) stimulate bile secretion in isolated rat hepatocyte couplets, but not in isolated bile duct units.
HEPATOLOGY 1998 28: 531A-531A.
Web of Science

 

1997

Full paper/article (Journal)

** Koeppel, TA; Thies, JC; Schemmer, P; Trauner, M; Gebhard, MM; Otto, G; Post, S Inhibition of nitric oxide synthesis in ischemia/reperfusion of the rat liver is followed by impairment of hepatic microvascular blood flow.
J Hepatol. 1997; 27(1):163-169 Doi: 10.1016/S0168-8278(97)80297-8
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** Koeppel, TA; Trauner, M; Baas, JC; Thies, JC; Schlosser, SF; Post, S; Gebhard, MM; Herfarth, C; Boyer, JL; Otto, G Extrahepatic biliary obstruction impairs microvascular perfusion and increases leukocyte adhesion in rat liver.
Hepatology. 1997; 26(5):1085-1091 Doi: 10.1002/hep.510260501 [OPEN ACCESS]
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** Trauner, M; Arrese, M; Soroka, CJ; Ananthanarayanan, M; Koeppel, TA; Schlosser, SF; Suchy, FJ; Keppler, D; Boyer, JL The rat canalicular conjugate export pump (Mrp2) is down-regulated in intrahepatic and obstructive cholestasis.
Gastroenterology. 1997; 113(1):255-264 Doi: 10.1016/S0016-5085(97)70103-3
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** Trauner, M; Nathanson, MH; Mennone, A; Rydberg, SA; Boyer, JL Nitric oxide donors stimulate bile flow and glutathione disulfide excretion independent of guanosine 3',5'-cyclic [corrected] monophosphate in the isolated perfused rat liver.
Hepatology. 1997; 25(2):263-269 Doi: 10.1002/hep.510250202 [OPEN ACCESS]
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** Trauner, M; Nathanson, MH; Rydberg, SA; Koeppel, TA; Gartung, C; Sessa, WC; Boyer, JL Endotoxin impairs biliary glutathione and HCO3- excretion and blocks the choleretic effect of nitric oxide in rat liver.
Hepatology. 1997; 25(5):1184-1191 Doi: 10.1002/hep.510250522 [OPEN ACCESS]
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Review

** Trauner, M Molecular alterations of canalicular transport systems in experimental models of cholestasis: possible functional correlations.
Yale J Biol Med. 1997; 70(4):365-378 [OPEN ACCESS]
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Abstract (Journal)

** Arrese, M; Trauner, M; Ananthanarayanan, M; Boyer, JL; Suchy, FJ Maternal cholestasis does not affect the ontogenic pattern of expression of the Na+/taurocholate cotransporting polypeptide
GASTROENTEROLOGY 1997 112: A1215-A1215.
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** Arrese, M; Trauner, M; Ananthanarayanan, M; Koeppel, T; Boyer, JL; Suchy, FJ Adaptive regulation of bile salt transport in experimental diabetes: Role of basolateral and canalicular transporters.
HEPATOLOGY 1997 26: 653-653.
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** Arrese, M; Trauner, M; Goldberg, DI; Crossman, M; Shneider, BL Neither intestinal sequestration of bile acids nor common bile duct ligation modulate the expression or function of the rat ileal bile acid transporter
HEPATOLOGY 1997 26: 654-654.
Web of Science

 

** Koeppel, TA; Trauner, M; Baas, JC; Thies, JC; Schlosser, SF; Post, S; Boyer, JL; Otto, G Impairment of the hepatic microcirculation in the bile duct ligated rat.
GASTROENTEROLOGY 1997 112: A1306-A1306.
Web of Science

 

** Koeppel, TA; Trauner, M; Mennone, A; Arrese, M; Boyer, JL Glutathione is a driving force for hepatic bile formation following cold ischemia of the rat liver
HEPATOLOGY 1997 26: 144-144.
Web of Science

 

** Trauner, M; Arrese, M; Lee, HR; Boyer, JL; Karpen, SJ Endotoxin-induced down-regulation of the rat liver Na+/taurocholate cotransporter (ntcp) gene is mediated by decreased activity of hepatocyte nuclear factor 1 (HNF 1).
HEPATOLOGY 1997 26: 535-535.
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1996

Full paper/article (Journal)

** Schreiber, F; Gurakuqi, GC; Pristautz, H; Trauner, M; Schnedl, W Sonographically-guided extracorporeal shockwave lithotripsy for pancreatic stones in patients with chronic pancreatitis.
J Gastroenterol Hepatol. 1996; 11(3):247-251 Doi: 10.1111/j.1440-1746.1996.tb00070.x
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** Schreiber, F; Steindorfer, P; Pristautz, H; Gurakuqi, GC; Schnedl, W; Trauner, M Complications and surgical interventions during 4 years of biliary extracorporeal shockwave lithotripsy.
Hepatogastroenterology. 1996; 43(11):1124-1128
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** Stauber, RE; Heinemann, A; Trauner, M; Krejs, GJ Divergent effects of propranolol and nadolol in isolated mesenteric arteries from normal and portal hypertensive rats.
Eur J Clin Invest. 1996; 26(8):676-680 Doi: 10.1111/j.1365-2362.1996.tb02152.x
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Short report/Letter

** Stauber, RE; Stepan, V; Trauner, M; Wilderstruschnig, M; Leb, G; Krejs, GJ Superior Diagnostic-Accuracy of Carbohydrate-Deficient Transferrin over Gamma-Glutamyl-Transferase - Reply
ALCOHOL ALCOHOLISM 1996 31: 306-306. Doi: 10.1093/oxfordjournals.alcalc.a008152 [OPEN ACCESS]
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Abstract (Journal)

** Arrese, M; Ananthanarayanan, M; Trauner, M; Boyer, JL; Suchy, FJ Effect of pregnancy on mRNA expression of liver transporters.
HEPATOLOGY 1996 24: 353-353.
Web of Science

 

** Gartung, C; Trauner, M; Schlosser, SF; Hagenbuch, B; Meier, PJ; Boyer, JL Sodium-independent uptake of bile acids is unaffected by down-regulation of an organic anion transporter (oatp) in rat liver during cholestasis produced by common bile duct ligation (CBDL).
HEPATOLOGY 1996 24: 970-970.
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** Gartung, C; Trauner, M; Schuele, S; Boyer, JL Role of TNF-alpha steroids and estrogens in the regulation of the Na+/taurocholate cotransporter (ntcp) in rat liver during the early phase of extrahepatic cholestasis.
HEPATOLOGY 1996 24: 971-971.
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** Trauner, M; Ananthanarayanan, M; Yi, JR; Arrese, M; Kaplowitz, N; Boyer, JL Effects of endotoxin on the expression of the canalicular glutathione (GSH) and multispecific organic anion transporters (cMOAT) in rat liver
HEPATOLOGY 1996 24: 359-359.
Web of Science

 

** Trauner, M; Gartung, C; Schlosser, SF; Boyer, JL Role of nitric oxide in the transcriptional regulation of bile acid transporters in endotoxin - Induced cholestasis.
GASTROENTEROLOGY 1996 110: A1349-A1349.
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** Trauner, M; Mennone, A; Nathanson, MH; Boyer, JL Nitric oxide stimulates bile secretion in isolated rat hepatocyte couplets, but not in isolated bile duct units.
J INVEST MED 1996 44: A301-A301.
Web of Science

 

Comment

** Schreiber, F; Gurakuqi, GC; Schnedl, W; Trauner, M ERCP and balloon dilation is a valuable alternative to surgical biliodigestive anastomosis in the long common channel syndrome in childhood.
Endoscopy. 1996; 28(8):724-725 Doi: 10.1055/s-2007-1005585
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1995

Full paper/article (Journal)

** Groell, R; Kugler, C; Aschauer, M; Rienmueller, R; Stauber, R; Trauner, M; Mischinger, HJ Quantitative perfusion parameters of focal nodular hyperplasia and normal liver parenchyma as determined by electron beam tomography.
Br J Radiol. 1995; 68(815):1185-1189 Doi: 10.1259/0007-1285-68-815-1185
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** Schmidt, F; Penka, B; Trauner, M; Reinsperger, L; Ranner, G; Ebner, F; Waldhauser, F Lack of pineal growth during childhood.
J Clin Endocrinol Metab. 1995; 80(4):1221-1225 Doi: 10.1210/jc.80.4.1221 [OPEN ACCESS]
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** Schreiber, F; Gurakuqi, GC; Trauner, M Endoscopic intracorporeal laser lithotripsy of difficult common bile duct stones with a stone-recognition pulsed dye laser system.
Gastrointest Endosc. 1995; 42(5):416-419 Doi: 10.1016/S0016-5107(95)70042-0
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** Stauber, RE; Stepan, V; Trauner, M; Wilders-Truschnig, M; Leb, G; Krejs, GJ Evaluation of carbohydrate-deficient transferrin for detection of alcohol abuse in patients with liver dysfunction.
Alcohol Alcohol. 1995; 30(2):171-176
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** Trauner, M; Grasmug, E; Stauber, RE; Hammer, HF; Hoefler, G; Reisinger, EC Recurrent Salmonella enteritidis sepsis and hepatic tuberculosis.
Gut. 1995; 37(1):136-139 Doi: 10.1136/gut.37.1.136 (- Case Report) [OPEN ACCESS]
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** Trauner, M; Klimpfinger, M; Stauber, RE; Schreiber, F; Stöger, H; Krejs, GJ Laparoscopic diagnosis of peritoneal serous papillary carcinoma.
Endoscopy. 1995; 27(4):337-341 Doi: 10.1055/s-2007-1005704 (- Case Report)
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Review

** Abrams, GA; Trauner, M; Nathanson, MH Nitric oxide and liver disease.
Gastroenterologist. 1995; 3(3):220-233
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Abstract (Journal)

** SCHREIBER, F; GURAKUQI, GCH; TRAUNER, M ENDOSCOPIC INTRACORPOREAL LASER LITHOTRIPSY WITH A STONE RECOGNITION PULSED DYE-LASER SYSTEM - A NEW APPROACH TO DIFFICULT COMMON BILE-DUCT STONES
GASTROENTEROLOGY 1995 108: A435-A435. Doi: 10.1016/0016-5085(95)26054-4
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** TRAUNER, M; NATHANSON, MH; MENNONE, A; RYDBERG, SA; BRUCK, R; BOYER, JL NITRIC-OXIDE STIMULATES BILE-FLOW AND GLUTATHIONE EXCRETION INDEPENDENT OF CYCLIC-GMP-INDUCED HCO3- EXCRETION
HEPATOLOGY 1995 22: 834-834.
Web of Science

 

** TRAUNER, M; NATHANSON, MH; RYDBERG, SA; GARTUNG, C; SESSA, WC; BOYER, JL NITRIC-OXIDE - INDUCED CHOLERESIS IS IMPAIRED IN ISOLATED-PERFUSED LIVERS OF ENDOTOXEMIC RATS
HEPATOLOGY 1995 22: 836-836.
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1994

Full paper/article (Journal)

** Schreiber, F; Gurakuqi, GC; Trauner, M; Krejs, GJ Ultrasound controlled extracorporeal shockwave lithotripsy of pancreatic calculi in patients with chronic recurrent pancreatitis].
Bildgebung. 1994; 61(3):182-186
PubMed

 

** Stauber, RE; Horina, JH; Trauner, M; Krejs, GJ; Ratschek, M; Klimpfinger, M Glomerulonephritis as late manifestation of severe alpha 1-antitrypsin deficiency.
Clin Investig. 1994; 72(5):404-408 Doi: 10.1007/BF00252839 (- Case Report)
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** Trauner, M; Grygar, S; Stauber, RE; Brodatsch-Häusler, E; Klimpfinger, M Carcinoembryonic antigen, cytokeratin expression and mucin composition in hyperplastic and neoplastic polyps of the colorectum.
Z Gastroenterol. 1994; 32(11):626-631
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Abstract (Journal)

** HEINEMANN, A; TRAUNER, MH; STAUBER, RE NADOLOL INCREASES WHEREAS PROPRANOLOL REDUCES RESISTANCE IN MESENTERIC ARTERIAL BEDS OF RATS
GASTROENTEROLOGY. 1994; 106(4): A905-A905.
Web of Science

 

1993

Full paper/article (Journal)

** Garrick, T; Grijalva, CV; Trauner, M Lateral hypothalamic lesions cause gastric injury by stimulating gastric contractility.
Am J Physiol. 1993; 265(1 Pt 1):G138-G142 Doi: 10.1152/ajpgi.1993.265.1.G138
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Review

** Stauber, RE; Mischinger, HJ; Trauner, M; Pristautz, H Indications for liver transplantation in neoplasms of the liver.
Acta Med Austriaca. 1993; 20(3):57-60
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Abstract (Journal)

** STAUBER, RE; TRAUNER, MH; HAUSEGGER, K; PETRITSCH, W IMPROVEMENT OF LIVER-FUNCTION AFTER TRANSJUGULAR INTRAHEPATIC PORTASYSTEMIC SHUNT (TIPS) IN A PATIENT WITH CHRONIC BUDD-CHIARI SYNDROME
HEPATOLOGY. 1993; 18(4): A344-A344. Doi: 10.1016/0270-9139(93)92899-B
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** TRAUNER, MH; HEINEMANN, A; STAUBER, RE EFFECT OF PROPRANOLOL ON PRESSOR-RESPONSES TO NOREPINEPHRINE IN MESENTERIC ARTERIAL BEDS OF NORMAL AND PORTAL HYPERTENSIVE RATS
HEPATOLOGY. 1993; 18(4): A287-A287. Doi: 10.1016/0270-9139(93)92672-M
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1992

Full paper/article (Journal)

** Garrick, T; Yang, H; Trauner, M; Livingston, E; Taché, Y Thyrotropin-releasing hormone analog injected into the raphe pallidus and obscurus increases gastric contractility in rats.
Eur J Pharmacol. 1992; 223(1):75-81 Doi: 10.1016/0014-2999(92)90820-T
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Review

** Trauner, M; Stepan, KM; Resch, M; Ebner, F; Pristautz, H; Klimpfinger, M Diagnostic problems in nodular regenerative hyperplasia (nodular transformation) of the liver. Review of the literature and report of two cases.
Z Gastroenterol. 1992; 30(3):187-194 (- Case Report)
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1991

Full paper/article (Journal)

** Heymann-Mönnikes, I; Taché, Y; Trauner, M; Weiner, H; Garrick, T CRF microinjected into the dorsal vagal complex inhibits TRH analog- and kainic acid-stimulated gastric contractility in rats.
Brain Res. 1991; 554(1-2):139-144 Doi: 10.1016/0006-8993(91)90181-T
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