** = Publikationen gelistet in SCI/SSCI/Pubmed
** Birnhuber, A; Jandl, K; Biasin, V; Fließer, E; Valzano, F; Marsh, LM; Krolczik, C; Olschewski, A; Wilhelm, J; Toller, W; Heinemann, A; Olschewski, H; Wygrecka, M; Kwapiszewska, G
Pirfenidone exacerbates Th2-driven vasculopathy in a mouse model of systemic sclerosis-associated interstitial lung disease.
Eur Respir J. 2022; 60(4):
Doi: 10.1183/13993003.02347-2021
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** Birnhuber, A; Biasin, V; Jain, P; Boiarina, E; Nagaraj, C; Olschewski, A; Witzenrath, M; Marsh, LM; Tabeling, C; Kwapiszewska, G
Th2-mediated pulmonary vascular hyperresponsiveness and remodelling in a mouse model of systemic sclerosis associated pulmonary arterial hypertension
WIEN KLIN WOCHENSCHR. 2022; 134(19-20):725-725.-Jahrestagung der Österreichischen Gesellschaft für Pneumologie; Salzburg, AUSTRIA.
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** Biasin, V; Crnkovic, S; Sahu-Osen, A; Birnhuber, A; El Agha, E; Sinn, K; Klepetko, W; Olschewski, A; Bellusci, S; Marsh, LM; Kwapiszewska, G
PDGFRα and αSMA mark two distinct mesenchymal cell populations involved in parenchymal and vascular remodeling in pulmonary fibrosis.
Am J Physiol Lung Cell Mol Physiol. 2020; 318(4):L684-L697
Doi: 10.1152/ajplung.00128.2019
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** Bordag, N; Biasin, V; Schnoegl, D; Valzano, F; Jandl, K; Nagy, BM; Sharma, N; Wygrecka, M; Kwapiszewska, G; Marsh, LM
Machine Learning Analysis of the Bleomycin Mouse Model Reveals the Compartmental and Temporal Inflammatory Pulmonary Fingerprint.
iScience. 2020; 23(12):101819-101819
Doi: 10.1016/j.isci.2020.101819
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** Birnhuber, A; Egemnazarov, B; Biasin, V; Bonyadi Rad, E; Wygrecka, M; Olschewski, H; Kwapiszewska, G; Marsh, LM
CDK4/6 inhibition enhances pulmonary inflammatory infiltration in bleomycin-induced lung fibrosis.
Respir Res. 2020; 21(1):167-167
Doi: 10.1186/s12931-020-01433-w
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** Biasin, V; Crnkovic, S; Sahu-Osen, A; Birnhuber, A; El Agha, E; Sinn, K; Klepetko, W; Olschewski, A; Bellusci, S; Marsh, LM; Kwapiszewska, G
PDGFRa and aSMA mark two distinct mesenchymal cell populations involved in parenchymal and vascular remodeling in pulmonary fibrosis.
EUR RESPIR J. 2020; 56:
Doi: 10.1183/13993003.congress-2020.3374
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** Birnhuber, A; Crnkovic, S; Marsh, LM; Biasin, V; Wilhelm, J; Graninger, W; Olschewski, A; Olschewski, H; Kwapiszewska, G
Exacerbated Lung Function and Eosinophilic Inflammation After Blockage of Innate Immune Signalling in a Mouse Model of Systemic Sclerosis-Associated Lung Fibrosis.
AM J RESP CRIT CARE. 2020; 201: -International Conference of the American-Thoracic-Society; 2020; ELECTR NETWORK.
[Onlinepräsentation]
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** Birnhuber, A; Crnkovic, S; Marsh, LM; Biasin, V; Wilhelm, J; Olschewski, H; Kwapiszewska, G
Pirfenidone exacerbates inflammatory influx to the lung in a mouse model of systemic sclerosis.
WIEN KLIN WOCHENSCHR. 2020; 132(19-20):617-618.
[Poster]
Web of Science
** Birnhuber, A; Egemnazarov, B; Biasin, V; Rad, EB; Olschewski, H; Kwapiszewska, G; Marsh, L
The CDK4/6 inhibitor, palbociclib intensifies pulmonary inflammation in bleomycin-induced lung fibrosis.
EUR RESPIR J. 2020; 56:
Doi: 10.1183/13993003.congress-2020.2285
[Poster]
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** Crnkovic, S; Biasin, V; Osen, AS; Birnhuber, A; El Agha, E; Sinn, K; Klepetko, W; Olschewski, A; Bellusci, S; Marsh, LM; Kwapiszewska, G
Compartment-Specific Remodeling in Pulmonary Fibrosis Is Characterized by Involvement of Two Distinct Mesenchymal Cell Lineages.
AM J RESP CRIT CARE. 2020; 201: -International Conference of the American-Thoracic-Society; 2020; ELECTR NETWORK.
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** Marsh, LM; Bordag, N; Biasin, V; Nagy, B; Sharma, N; Jandl, K; Kwapiszewska, G
Modelling of the Inflammatory Cell Kinetics Underlying Bleomycin-Induced Lung Fibrosis Reveals Chronic Persistent Inflammation (B34).
AM J RESP CRIT CARE. 2020; 201: -International Conference of the American-Thoracic-Society; AUG 5-10, 2020; New York, United States of America.
[Onlinepräsentation]
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** Birnhuber, A; Crnkovic, S; Biasin, V; Marsh, LM; Odler, B; Sahu-Osen, A; Stacher-Priehse, E; Brcic, L; Schneider, F; Cikes, N; Ghanim, B; Klepetko, W; Graninger, W; Allanore, Y; Eferl, R; Olschewski, A; Olschewski, H; Kwapiszewska, G
IL-1 receptor blockade skews inflammation towards Th2 in a mouse model of systemic sclerosis.
Eur Respir J. 2019; 54(3):
Doi: 10.1183/13993003.00154-2019
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** Kheirollahi, V; Wasnick, RM; Biasin, V; Vazquez-Armendariz, AI; Chu, X; Moiseenko, A; Weiss, A; Wilhelm, J; Zhang, JS; Kwapiszewska, G; Herold, S; Schermuly, RT; Mari, B; Li, X; Seeger, W; Günther, A; Bellusci, S; El Agha, E
Metformin induces lipogenic differentiation in myofibroblasts to reverse lung fibrosis.
Nat Commun. 2019; 10(1): 2987-2987.
Doi: 10.1038/s41467-019-10839-0
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** Birnhuber, A; Biasin, V; Schnoegl, D; Marsh, LM; Kwapiszewska, G
Transcription factor Fra-2 and its emerging role in matrix deposition, proliferation and inflammation in chronic lung diseases.
Cell Signal. 2019; 64:109408-109408
Doi: 10.1016/j.cellsig.2019.109408
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** Birnhuber, A; Crnkovic, S; Marsh, LM; Biasin, V; Graninger, W; Olschewski, A; Olschewski, H; Kwapiszewska, G
Targeting innate immunity exacerbates inflammation and pulmonary fibrosis in a systemic sclerosis-associated lung disease model
WIEN KLIN WOCHENSCHR. 2019; 131(19-20):512-512.
[Oral Communication]
Web of Science
** Biasin, V; Wygrecka, M; Bärnthaler, T; Jandl, K; Jain, PP; Bálint, Z; Kovacs, G; Leitinger, G; Kolb-Lenz, D; Kornmueller, K; Peters, F; Sinn, K; Klepetko, W; Heinemann, A; Olschewski, A; Becker-Pauly, C; Kwapiszewska, G
Docking of Meprin α to Heparan Sulphate Protects the Endothelium from Inflammatory Cell Extravasation.
Thromb Haemost. 2018; 118(10):1790-1802
Doi: 10.1055/s-0038-1670657
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** Gungl, A; Biasin, V; Wilhelm, J; Olschewski, A; Kwapiszewska, G; Marsh, LM
Fra2 Overexpression in Mice Leads to Non-allergic Asthma Development in an IL-13 Dependent Manner.
Front Immunol. 2018; 9(10):2018-2018
Doi: 10.3389/fimmu.2018.02018
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** Gungl, A; Biasin, V; Slaven, C; Marsh, LM; Kwapiszewska, G; Olschewski, H
Eosinophilic inflammation and worsening of lung function upon pirfenidone treatment in Fra-2 transgenic mice
EUR RESPIR J. 2018; 52: -28th International Congress of the European-Respiratory-Society (ERS); SEP 15-19, 2018; Paris, FRANCE.
Doi: 10.1183/13993003.congress-2018.PA997
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** Gungl, A; Slaven, C; Biasin, V; Marsh, LM; Odler, B; Sahu-Osen, A; Brcic, L; Ghanim, B; Klepetko, W; Graninger, W; Olschewski, A; Olschewski, H; Kwapiszewska, G
Blockade of IL-1 signalling exacerbates Th2 inflammation in the Fra-2 transgenic mouse model of systemic sclerosis
WIEN KLIN WOCHENSCHR. 2018; 130(19-20):605-606.
[Poster]
Web of Science
** Marsh, LM; Gungl, A; Biasin, V; Olschewski, A; Kwapiszewska, G
AP-1 Subunit Overexpression Drives a Non-Allergic Asthma Phenotype in Mice
American Journal of Respiratory and Critical Care Medicine 2018;197:A1299. 2018; 197: -ATS 2018; May 18-23, 2018; San Diego, USA.
[Poster]
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** Bedau, T; Peters, F; Prox, J; Arnold, P; Schmidt, F; Finkernagel, M; Köllmann, S; Wichert, R; Otte, A; Ohler, A; Stirnberg, M; Lucius, R; Koudelka, T; Tholey, A; Biasin, V; Pietrzik, CU; Kwapiszewska, G; Becker-Pauly, C
Ectodomain shedding of CD99 within highly conserved regions is mediated by the metalloprotease meprin β and promotes transendothelial cell migration.
FASEB J. 2017; 31(3):1226-1237
Doi: 10.1096/fj.201601113R
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** Biasin, V; Wygrecka, M; Marsh, LM; Becker-Pauly, C; Brcic, L; Ghanim, B; Klepetko, W; Olschewski, A; Kwapiszewska, G
Meprin β contributes to collagen deposition in lung fibrosis.
Sci Rep. 2017; 7(1):39969-39969
Doi: 10.1038/srep39969
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** Gungl, A; Crnkovic, S; Biasin, V; Marsh, LM; Sahu-Osen, A; Stacher-Priehse, E; Brcic, L; Schneider, F; Cikes, N; Ghanim, B; Klepetko, W; Odler, B; Kovacs, G; Eferl, R; Olschewski, H; Olschewski, A; Kwapiszewska, G
Fos-Related Antigen 2 (fra-2)-Driven Interleukin-1 Expression Leads To Pulmonary Remodelling Via Interleukin-6 And Tenascin C In Systemic Sclerosis
AM J RESP CRIT CARE. 2017; 195: -International Conference of the American-Thoracic-Society (ATS); MAY 19-24, 2017; Washington, USA.
[Oral Communication]
Web of Science
** Biasin, V; Gungl, A; Marsh, LM; Crnkovic, S; Oslchewski, A; Kwapiszewska, G
Female prevalence in systemic sclerosis is mirrored in Fra-2 over-expressing mice
WIEN KLIN WOCHENSCHR. 2016; 128(19-20):763-763.
[Poster]
Web of Science
** Gungl, A; Crnkovic, S; Biasin, V; Marsh, L; Sahu-Osen, A; Stacher-Priehse, E; Brcic, L; Schneider, F; Cikes, N; Ghanim, B; Klepetko, W; Odler, B; Kovacs, G; Eferl, R; Olschewski, H; Olschewski, A; Kwapiszewska, G
Fra-2 induces IL-1/IL-6-driven parenchymal and vascular remodelling in systemic sclerosis
WIEN KLIN WOCHENSCHR. 2016; 128(19-20):762-763.
[Oral Communication]
Web of Science
** Biasin, V; Wygrecka, M; Gungl, A; Ghanim, B; Klepetko, W; Marsh, LM; Olschewski, A; Kwapiszewska, G
Involvement of the proteases meprins in human lung fibrosis
WIEN KLIN WOCHENSCHR. 2015; 127(19-20):817-818.
[Oral Communication]
Web of Science
** Biasin, V; Chwalek, K; Wilhelm, J; Best, J; Marsh, LM; Ghanim, B; Klepetko, W; Fink, L; Schermuly, RT; Weissmann, N; Olschewski, A; Kwapiszewska, G
Endothelin-1 driven proliferation of pulmonary arterial smooth muscle cells is c-fos dependent.
Int J Biochem Cell Biol. 2014; 54(3):137-148
Doi: 10.1016/j.biocel.2014.06.020
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** Biasin, V; Marsh, LM; Egemnazarov, B; Wilhelm, J; Ghanim, B; Klepetko, W; Wygrecka, M; Olschewski, H; Eferl, R; Olschewski, A; Kwapiszewska, G
Meprin β, a novel mediator of vascular remodelling underlying pulmonary hypertension.
J Pathol. 2014; 233(1):7-17
Doi: 10.1002/path.4303
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** Berti, M; Ray Chaudhuri, A; Thangavel, S; Gomathinayagam, S; Kenig, S; Vujanovic, M; Odreman, F; Glatter, T; Graziano, S; Mendoza-Maldonado, R; Marino, F; Lucic, B; Biasin, V; Gstaiger, M; Aebersold, R; Sidorova, JM; Monnat, RJ; Lopes, M; Vindigni, A
Human RECQ1 promotes restart of replication forks reversed by DNA topoisomerase I inhibition.
Nat Struct Mol Biol. 2013; 20(3): 347-354.
Doi: 10.1038/nsmb.2501
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