Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz

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Wagner Martin |

** = Publikationen gelistet in SCI/SSCI/Pubmed

** Fickert, P; Wagner, M Preface - Animal models in liver disease
BBA-MOL BASIS DIS. 2019; 1865(5): 867-868.
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** Liu, L; Panzitt, K; Racedo, S; Wagner, M; Platzer, W; Zaufel, A; Theiler-Schwetz, V; Obermayer-Pietsch, B; Müller, H; Höfler, G; Heinemann, A; Zollner, G; Fickert, P Bile acids increase steroidogenesis in cholemic mice and induce cortisol secretion in adrenocortical H295R cells via S1PR2, ERK and SF-1.
Liver Int. 2019; 11(4): [OPEN ACCESS]
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** Al-Dury, S; Wahlstrom, A; Katrin, P; Anders, T; Stahlman, M; Olsson, L; Trauner, M; Fickert, P; Moore, D; Backhed, F; Fandriks, L; Wagner, M; Marschall, HU FXR agonist obeticholic acid increases gallbladder FGF19 in gallstone patients
J HEPATOL. 2018; 68: S449-S449.
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** Al-Dury, S; Wahlstrom, A; Panzitt, K; Thorell, A; Stahlman, M; Trauner, MH; Fickert, P; Backhed, F; Fandriks, L; Wagner, M; Marschall, HU Obeticholic Acid Increases Cholesterol Saturation and FGF19 in Human Gallbladder Bile
HEPATOLOGY. 2018; 68: 159A-159A.-Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD) / Liver Meeting; NOV 09-13, 2018; San Francisco, CA. [Oral Communication]
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** Durchschein, F; Krones, E; Pollheimer, MJ; Zollner, G; Wagner, M; Raufman, JP; Fickert, P Genetic loss of the muscarinic M3 receptor markedly alters bile formation and cholestatic liver injury in mice.
Hepatol Res. 2018; 48(3):E68-E77 [OPEN ACCESS]
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** Fabian, E; Auer, H; Kump, P; Krause, R; Wagner, M; Fuchsjäger, M; Janek, E; Olschewski, H; Krejs, GJ Clinical-Pathological Conference Series from the Medical University of Graz : Case No 168: A 28-year-old Syrian refugee with severe abdominal pain and eosinophilia.
Wien Klin Wochenschr. 2018; 130(19-20):581-588 [OPEN ACCESS]
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Jungwirth, Emilian; Panzitt, Katrin; Wagner Martin; Thallinger, Gerhard G. Bioinformatic Analysis of FXR related ChIP-seq data
Proceedings of GCB 2018. 2018; -German Conference on Bioinformatics (GCB) 2018; SEP 26-28, 2018; Vienna, AUSTRIA. [Poster]
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** Kump, P; Wurm, P; Gröchenig, HP; Wenzl, H; Petritsch, W; Halwachs, B; Wagner, M; Stadlbauer, V; Eherer, A; Hoffmann, KM; Deutschmann, A; Reicht, G; Reiter, L; Slawitsch, P; Gorkiewicz, G; Högenauer, C The taxonomic composition of the donor intestinal microbiota is a major factor influencing the efficacy of faecal microbiota transplantation in therapy refractory ulcerative colitis.
Aliment Pharmacol Ther. 2018; 47(1):67-77 [OPEN ACCESS]
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** Song, P; Zechner, C; Hernandez, G; Cánovas, J; Xie, Y; Sondhi, V; Wagner, M; Stadlbauer, V; Horvath, A; Leber, B; Hu, MC; Moe, OW; Mangelsdorf, DJ; Kliewer, SA The Hormone FGF21 Stimulates Water Drinking in Response to Ketogenic Diet and Alcohol.
Cell Metab. 2018; 27(6):1338-1347 [OPEN ACCESS]
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** Wagner, M; Fickert, P Time for the dawn of multimodal therapies and the dusk for mono-therapeutic trials for cholestatic liver diseases?
Liver Int. 2018; 38(6):991-994 [OPEN ACCESS]
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** Douschan, P; Kovacs, G; Stadlbauer, V; Kniepeiss, D; Krones, E; Durchschein, F; Rainer, F; Spindelboeck, W; Wagner, M; Zollner, G; Avian, A; Fickert, P; Olschewski, A; Olschewski, H; Stauber, RE Exercise capacity and exercise hemodynamics in the screening for pulmonary vascular disease (PVD) in patients with portal hypertension - results from a prospective cross-sectional study
J HEPATOL. 2017; 66(1):S568-S569.-International Liver Congress / 52nd Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 19-23, 2017; Amsterdam, NETHERLANDS. [Poster]
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** Fickert, P; Wagner, M Biliary bile acids in hepatobiliary injury - What is the link?
J Hepatol. 2017; 67(3):619-631
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Horvath, A; Grande, P; Rainer, F; Blesl, A; Meinitzer, A; Leber, B; Schmerböck, B; Komarova, I; Fickert, P; Stiegler, P; Wagner, M; Stadlbauer, V FGF21 in acute and chronic alcohol consumption
Zeitschrift für Gastroenterologie, Ausgabe 05, Volume 55, Mai 2017. 2017; -Jahrestagung der ÖGGH; JUN 9-10 2017; Linz. [Poster]

 

Panzitt, K; Marschall, HU; Trauner, M;Fickert, P; Wagner, M The autophagy inhibitor Rubicon is a direct target of the bile acid receptor FXR in human liver and is induced in human cholestasis
Keystone. 2017; -Keystone bile acid meeting; March 5-9, 2017; Monterey, USA. [Poster]

 

** Grande, P; Horvath, A; Wagner, M; Stadlbauer, V FGF21 and its connection to alcohol consumption
WIEN KLIN WOCHENSCHR. 2016; 128: S384-S384. [Poster]
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** Krones, E; Bork, T; Grahammer, F; Wagner, M; Rosenkranz, AR; Huber, TB; Fickert, P ACCUMULATION OF LC3 II IN CHOLEMIC NEPHROPATHY IS CAUSED BY BLOCKAGE OF AUTOPHAGIC FLUX
NEPHROL DIAL TRANSPL. 2016; 31: 103-104.-53rd ERA-EDTA Congress; MAY 21-24, 2016; Vienna, AUSTRIA. [Poster]
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** Krones, E; Wagner, M Fibroblast growth factor 19 meets mammalian target of rapamycin: A mitogenic Tête-à-Tête under consideration.
Hepatology. 2016; 64(4):1028-1030
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** Panzitt, K; Marschall, HU; Moore, DD; Trauner, MH; Fickert, P; Wagner, M The autophagy inhibitor Rubicon is a direct target of the bile acid receptor FXR in human liver and is induced in human cholestasis
HEPATOLOGY. 2016; 63(1 SUPP):159A-159A.-67th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD); NOV 11-15, 2016; Boston, MA. [Poster]
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Panzitt, K; Marschall, HU; Trauner, M; Fickert, P; Wagner,M; The autophagy inhibitor Rubicon is a direct FXR target in human liver and is induced in human cholestasis
Proceedings of the XXIV International Bile Acid Meeting. 2016; -XXIV International Bile Acid Meeting: Bile Acids in Health and Disease; JUN 17-18, 2016; Düsseldorf, GERMANY. [Poster]

 

Panzitt,K; Marschall, HU; Trauner, M; Fickert, P; Wagner, M; The autophagy inhibitor Rubicon is a direct target of the bile acid receptor FXR in human liver and is induced in human cholestasis
Keystone Symposia Abstract Book "Autophagy: Molecular and physiological mechanisms". 2016; -Autophagy: Molecular and Physiological Mechanisms (V1); JUN 5-9, 2016; Whistler, British Columbia, CANADA. [Poster]

 

PK Kump, P Wurm, HP Gröchenig, HH Wenzl, w Petritsch, B Halwachs, M wagner, V. Stadlbauer-Köllner, AJ Eherer, KM Hoffmann, A Deutschmann, G Reicht, L Reiter, P Slawitsch, G Gorkiewicz, C Högenauer Clinical Response to fecal microbiota Transplantation in chronic active ulcerative colitis depends on the taxonomic composition of the donor microbiota.
United European Gastroenterology Journal; 2016:2 (Supplement 1) . 2016; 2: -UEG week; 15.-19.10.2016; Wien. [Oral Communication]

 

** Schuller, M; Wagner, M; Panzitt, K Endogenous phosphatidylcholine generation via the PEMT pathway modulates LRH-1 signaling - Dietary clues for treating NAFLD?
WIEN KLIN WOCHENSCHR. 2016; 128: S383-S384. [Poster]
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** Wagner, M; Choi, S; Panzitt, K; Mamrosh, JL; Lee, JM; Zaufel, A; Xiao, R; Wooton-Kee, R; Ståhlman, M; Newgard, CB; Borén, J; Moore, DD Liver receptor homolog-1 is a critical determinant of methyl-pool metabolism.
Hepatology. 2016; 63(1):95-106 [OPEN ACCESS]
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** Wagner, M; Fickert, P; Zollner, G Secretin and cholestasis, two sides of a coin.
Hepatology. 2016; 64(3):714-716 [OPEN ACCESS]
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** Wagner, M; Trauner, M Recent advances in understanding and managing cholestasis.
F1000Res. 2016; 5(8): [OPEN ACCESS]
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** Hartig, SM; Bader, DA; Abadie, KV; Motamed, M; Hamilton, MP; Long, W; York, B; Mueller, M; Wagner, M; Trauner, M; Chan, L; Bajaj, M; Moore, DD; Mancini, MA; McGuire, SE Ubc9 Impairs Activation of the Brown Fat Energy Metabolism Program in Human White Adipocytes.
Mol Endocrinol. 2015; 29(9):1320-1333 [OPEN ACCESS]
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** Krones, E; Wagner, M; Eller, K; Rosenkranz, AR; Trauner, M; Fickert, P Bile acid-induced cholemic nephropathy.
Dig Dis. 2015; 33(3):367-375
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Panzitt, K; Marschall, H-U; Trauner, M; Fickert, P; Wagner, M; Effects of Ursodeoxycholic-acid and Rifampicin on autophagy in the liver
Hepatology. 2015; -AASLD 2015; 13.11. - 17.11.2015; San Francisco. [Poster]

 

Panzitt, K; Marschall, H-U; Trauner, M; Fickert, P; Wagner, M; Effects of Ursodeoxycholic-acid and Rifampicin on autophagy in the liver
UEG Journal. 2015; -UEG Week 2015; 24.10. - 28.10.2015; Barcelona. [Poster]

 

** Panzitt, K; Marschall, HU; Trauner, M; Fickert, P; Wagner, M Effects of Ursodeoxycholic-acid and Rifampicin on autophagy in the liver
HEPATOLOGY. . 2015; 62: 538A-538A.-66th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD); NOV 13-17, 2015; San Francisco, CA. [Oral Communication]
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** Wooton-Kee, CR; Jain, AK; Wagner, M; Grusak, MA; Finegold, MJ; Lutsenko, S; Moore, DD Elevated copper impairs hepatic nuclear receptor function in Wilson's disease.
J Clin Invest. 2015; 125(9):3449-3460 [OPEN ACCESS]
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Douschan, P; Kovacs, G; Stadlbauer-Koellner, V; Spindelboeck, W; Krones, E; Durchschein, F; Zollner, G; Rainer, F; Foris, V; Wagner, M; Fickert, P; Olschewski, H; Stauber, RE Cardiopulmonary response to exercise in patients with portal hypertension and early stages of liver cirrhosis.
Z Gastroenterol. 2014; 52 - P66: -47. Jahrestagung der Österreichischen Gesellschaft für Gastroenterologie und Hepatologie (ÖGGH); 12. – 14. Juni, 2014; Villach, AUSTRIA. [Poster]

 

** Lee, JM; Wagner, M; Xiao, R; Kim, KH; Feng, D; Lazar, MA; Moore, DD Nutrient-sensing nuclear receptors coordinate autophagy.
Nature. 2014; 516(7529): 112-115. [OPEN ACCESS]
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** Mamrosh, JL; Lee, JM; Wagner, M; Stambrook, PJ; Whitby, RJ; Sifers, RN; Wu, SP; Tsai, MJ; Demayo, FJ; Moore, DD Nuclear receptor LRH-1/NR5A2 is required and targetable for liver endoplasmic reticulum stress resolution.
Elife. 2014; 3(6):e01694-e01694 [OPEN ACCESS]
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** Zaufel, A; Wagner, M; Krones, E; Fickert, P; Zollner, G Cholestasis and Bile Acids start the Adrenocortical Function, Salzburg, 25th-27th September, 2014
WIEN KLIN WOCHENSCHR. 2014; 126(17-18):570-571. [Poster]
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Zaufel, A; Wagner, M; Krones, E; Fickert, P; Zollner, G. Cholestasis and Bile Acids Alter Adrenocortical Function
Proceedings of the XXIII International Bile Acid Meeting. 2014; -Falk Symposum, XXIII International Bile Acid Meeting; OCT 8-9, 2014; Freiburg, GERMANY. [Poster]

 

Zaufel, A; Wagner, M; Krones, E; Fickert, P; Zollner, G. Cholestasis and Bile Acids Alter Adrenocortical Function
Proceedings of the XXIII International Bile Acid Meeting. 2014; -Falk Symposium: XXIII International Bile Acid Meeting; OCT 8-9, 2014; Freiburg, GERMANY. [Oral Communication]

 

** Mueller, M; Marschall, HU; Claudel, T; Wagner, M; Fickert, P; Lackner, C; Einarsson, C; Thorell, A; Trauner, M URSODEOXYCHOLIC ACID COUNTERACTS LIPOTOXICITY AND INDUCES UNFOLDED PROTEIN RESPONSE IN MORBIDLY OBESE PATIENTS
J HEPATOL. . 2013; 58: S517-S517.-International Liver Congress / 48th Annual Meeting of the European-Association-for-the-Study-of-the-Liver (EASL); APR 24-28, 2013; Amsterdam, NETHERLANDS. [Poster]
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Marschall, HU; Mueller, M; Claudel, T; Wagner, M; Fickert, P; Zollner, G; Silbert, D; Lackner, K; Thorell, A; Trauner, M High Levels of Ursodeoxycholic Acid Act as FXR Antagonist and Deplete Liver Cholesterol due to Increased Bile Acid Synthesis in Morbidly Obese Patients.
classic paper presentation, electronic posters on the EASL member restricted website. 2012; -International Liver Congress(TM) 2012 by EASL; April 18-22, 2012; Barcelona, Spain. [Poster]

 

** Marschall, HU; Mueller, M; Wagner, M; Fickert, P; Zollner, G; Silbert, D; Lackner, C; Thorell, A; Trauner, M HIGH LEVELS OF URSODEOXYCHOLIC ACID ACT AS FXR ANTAGONIST AND DEPLETE LIVER CHOLESTEROL DUE TO INCREASED BILE ACID SYNTHESIS IN MORBIDLY OBESE PATIENTS
J HEPATOL. . 2012; 56: S515-S515.-47th Annual Meeting of the European-Association-for-the-Study-of-the-Liver (EASL); APR 18-22, 2012; Barcelona, SPAIN. [Poster]
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** Marschall, HU; Wagner, M; Zollner, G; Fickert, P; Silbert, D; Gustafsson, U; Sahlin, S; Trauner, M Combined rifampicin and ursodeoxycholic acid treatment does not amplify rifampicin effects on hepatic detoxification and transport systems in humans.
Digestion. 2012; 86(3):244-249
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** Wagner, M; Wooton-Kee, CR; Mamrosh, JL; Lee, JM; Xiao, R; Vareed, SK; Sreekumar, A; Moore, DD LRH-1 is a key regulator of carbon one metabolism and its loss protects from liver injury in the methionine-choline deficient NASH model
HEPATOLOGY. 2012; 56: 866A-867A.-63rd Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD); NOV 09-13, 2012; Boston, MA.
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** Claudel, T; Zollner, G; Wagner, M; Trauner, M Role of nuclear receptors for bile acid metabolism, bile secretion, cholestasis, and gallstone disease.
Biochim Biophys Acta. 2011; 1812(8):867-878 [OPEN ACCESS]
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** Marschall, HU; Wagner, M; Zollner, G; Fickert, P; Lackner, C; Thorell, A; Trauner, M Ursodeoxycholic acid for treatment of fatty liver disease and dyslipidemia in morbidly obese patients.
Dig Dis. 2011; 29(1):117-118
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** Wagner, M; Moore, DD Endoplasmic reticulum stress and glucose homeostasis
CURR OPIN CLIN NUTR METAB CA. 2011; 14(4): 367-373.
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** Wagner, M; Zollner, G; Trauner, M Nuclear receptors in liver disease.
HEPATOLOGY. 2011; 53(3): 1023-1034. [OPEN ACCESS]
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** Mader, JK; Bock, G; Wagner, M; Forrer, F; Lackner, C; Portugaller, RH; Fickert, P; Krejs, GJ; Pieber, TR Recurrent hypoglycemia in adults - a diagnostic challenge (case report).
WIEN KLIN WOCHENSCHR. 2010; 122(17-18):A7-A7.-ÖGIM; Sep 29-Oct. 1; Salzburg, Austria. [Poster]
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Mader, JM; Bock, G; Wagner, M; Forrer,F; Lackner, C; Portugaller, RH; Fickert, P; Krejs, GJ; Pieber, TR; Rezidivierende Hypoglykämie im Erwachsenenalter - eine diagnostische Herausforderung (Fallbericht).
Abstractband. 2010; -ÖGIM; 29.9-2.10.2010; Salzburg, Austria. [Poster]

 

** Stojakovic, T; Claudel, T; Putz-Bankuti, C; Fauler, G; Scharnagl, H; Wagner, M; Sourij, H; Stauber, RE; Winkler, K; Marz, W; Wascher, TC; Trauner, M LOW-DOSE ATORVASTATIN IMPROVES DYSLIPIDEMIA AND VASCULAR FUNCTION IN PATIENTS WITH PRIMARY BILIARY CIRRHOSIS AFTER ONE YEAR OF TREATMENT.
J HEPATOL. 2010; 52: S431-S432.-45th Annual Meeting of the European Association for the Study of the Liver (EASL); APR 14-18, 2010; Vienna, AUSTRIA. [Poster]
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** Stojakovic, T; Claudel, T; Putz-Bankuti, C; Fauler, G; Scharnagl, H; Wagner, M; Sourij, H; Stauber, RE; Winkler, K; März, W; Wascher, TC; Trauner, M Low-dose atorvastatin improves dyslipidemia and vascular function in patients with primary biliary cirrhosis after one year of treatment.
Atherosclerosis. 2010; 209(1): 178-183.
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** Trauner, M; Arrese, M; Wagner, M Fatty liver and lipotoxicity.
Biochim Biophys Acta. 2010; 1801(3): 299-310. [OPEN ACCESS]
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Trauner, M; Claudel, T; Fickert, P; Moustafa, T; Wagner, M Bile acids as regulators of hepatic lipid and glucose metabolism.
In: Manns, MP; Lehnert, H; Lohse, AW; Day, CP; Vergani, D; Negro, F; Diehl, AM; Gershwin, ME; editors(s). Falk liver conference: Immunology and Liver Disease – Liver and Metabolic Syndrome. Falk Workshop and Syposium 171; 2010.

 

** Trauner, M; Claudel, T; Fickert, P; Moustafa, T; Wagner, M Bile acids as regulators of hepatic lipid and glucose metabolism.
Dig Dis. 2010; 28(1):220-224
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Trauner, M; Fickert, P; Baghdasaryan, A; Claudel, T; Halilbasic, E; Moustafa, T; Wagner, M; Zollner, G New Insights into autoimmune cholangitis by animal models.
In: Manns, MP; Lehnert, H; Lohse, AW; Day, CP; Vergani, D; Negro, F; Diehl, AM; Gershwin, ME; editors(s). Falk liver conference: Immunolgoy and Liver Disease – Liver and Metabolic Syndrome. Falk Workshop and Syposium 171; 2010.

 

** Trauner, M; Fickert, P; Baghdasaryan, A; Claudel, T; Halilbasic, E; Moustafa, T; Wagner, M; Zollner, G New insights into autoimmune cholangitis through animal models.
Dig Dis. 2010; 28(1):99-104
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** Wagner, M; Zollner, G; Trauner, M Nuclear receptor regulation of the adaptive response of bile acid transporters in cholestasis.
SEMIN LIVER DIS. 2010; 30(2): 160-177. [OPEN ACCESS]
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** Zollner, G; Wagner, M; Trauner, M Nuclear receptors as drug targets in cholestasis and drug-induced hepatotoxicity.
Pharmacol Ther. 2010; 126(3):228-243
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** Fickert, P; Fuchsbichler, A; Moustafa, T; Wagner, M; Zollner, G; Halilbasic, E; Stöger, U; Arrese, M; Pizarro, M; Solís, N; Carrasco, G; Caligiuri, A; Sombetzki, M; Reisinger, E; Tsybrovskyy, O; Zatloukal, K; Denk, H; Jaeschke, H; Pinzani, M; Trauner, M Farnesoid X receptor critically determines the fibrotic response in mice but is expressed to a low extent in human hepatic stellate cells and periductal myofibroblasts.
Am J Pathol. 2009; 175(6):2392-2405 [OPEN ACCESS]
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** Fickert, P; Fuchsbichler, A; Wagner, M; Silbert, D; Zatloukal, K; Denk, H; Trauner, M The role of the hepatocyte cytokeratin network in bile formation and resistance to bile acid challenge and cholestasis in mice.
Hepatology. 2009; 50(3):893-899 [OPEN ACCESS]
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** Klein, K; Eloranta, JJ; Wagner, M; Trauner, M; Kullak-Ublick, GA Regulation of human concentrative nucleoside transporter-1 gene expression
NAUNYN-SCHMIED ARCH PHARMACOL. 2009; 379: 490- [Oral Communication]
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** Klein, K; Kullak-Ublick, GA; Wagner, M; Trauner, M; Eloranta, JJ Hepatocyte nuclear factor-4alpha and bile acids regulate human concentrative nucleoside transporter-1 gene expression.
Am J Physiol Gastrointest Liver Physiol. 2009; 296(4): G936-G947. [OPEN ACCESS]
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** Marschall, HU; Wagner, M; Zollner, G; Fickert, P; Lundasen, T; Gustafsson, U; Sahlin, S; Trauner, M STIMULATION OF HEPATOBILIARY DETOXIFICATION AND TRANSPORT SYSTEMS IN HUMAN LIVER BY COMBINED TREATMENT WITH RIFAMPICIN AND URSODEOXYCHOLIC ACID
J HEPATOL. 2009; 50: 675-Vienna, Austria. [Poster]
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Marshall, H; Wagner, M; Zoller, G; Fickert, P; Gustafsson, U; Sahlin, S; Trauner, M Combined treatment with rifamppicin and ursodeoxycholic acid in humans stimulates bile acid synthesis, detoxification and bilirubin elimination.
Gut2009; 58(SII):A49-A49.-GASTRO 2009 UEGW/WCOG; NOV 21-25,2009; London, GREAT BRITAIN. [Oral Communication]

 

** Stojakovic, T; Putz-Bankuti, C; Fauler, G; Scharnagl, M; Wagner, M; Sourij, H; Stauber, RE; Marz, W; Wascher, TC; Trauner, M Low-dose atorvastatin improves dyslipidemia and vascular function in patients with primary biliary cirrhosis after one year of treatment
WIEN KLIN WOCHENSCHR. 2009; 121(15-16):A26-A26.-40.Jahrestagung der Österreichischen Gesellschaft für Innere Medizin (ÖGIM); SEP 17-19, 2009; Vienna, AUSTRIA. [Poster]
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** Sturm, E; Wagner, M; Trauner, M Nuclear receptor ligands in therapy of cholestatic liver disease.
Front Biosci. 2009; 14(6):4299-4325
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Trauner, M; Moustafa, T; Fickert, P; Halilbasic, E; Guelly, C; Fuchsbichler, A; Denk, H; Zatloukal, K; Wagner, M; Zollner, G Side chain-shortened bile acids for the treatment of cholestasis: lessons from nor-ursodeoxycholic acid.
In: Beuers, U; Keppler, D; Leuschner, U; Stiehl, A; Trauner, M; editors(s). Bile Acids Biology and Therapeutic Actions. Dordrecht: Kluwer Academic Publishers; 2009.

 

** Wagner, M; Zollner, G; Trauner, M New molecular insights into the mechanisms of cholestasis.
J Hepatol. 2009; 51(3): 565-580. [OPEN ACCESS]
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Stojakovic, T; Putz-Bankuti, C; Fauler, G; Scharnagl, H; Wagner, M; Sourij, H; Stauber, RE; März, W; Wascher, TC; Trauner, M Improvement of dyslipidemia and vascular function in patients with primary biliary cirrhosis after long-term treatment with atorvastatin.
Clin Chem Lab Med. 2008; 46(9):A181-A181.-5. Jahrestagung der Deutschen Vereinten Gesellschaft für Klinische Chemie und Laboratoriumsmedizin (DGKL); SEP 21-24, 2008; Mannheim, GERMANY. [Poster]

 

Stojakovic, T; Putz-Bankuti, C; Scharnagl, H; Wagner, M; Sourij, H; März, W; Wascher, TC; Trauner, M Long-term treatment with atorvastatin improves dyslipidemia and vascular function in patients with primary biliary cirrhosis.
Z Gastroenterol. 2008; 45: 1-1.-41. Jahrestagung und 19. Fortbildungskurs der Österreichischen Gesellschaft für Gastroenterologie und Hepatologie (ÖGGH); MAI 29-31, 2008; Millstatt, AUSTRIA. [Oral Communication]

 

Stojakovic, T; Putz-Bankuti, C; Scharnagl, H; Wagner, M; Wascher, TC; März, W; Trauner, M. Improvement of dyslipidemia and vascular function in patients with cholestatic liver disease after long-term treatment with atorvastatin
Hämostaseologie. 2008; 28(1-2):A62-A62.-52. Jahrestagung der Gesellschaft für Thrombose- und Hämostaseforschung e. V. (GTH); FEB 20-23, 2008; Wiesbaden, Germany. [Poster]

 

Stojakovic, T; Putz-Bankuti, C; Wagner, M; Scharnagl, H; Wascher, TC; Marz, W; Trauner, M Long-term treatment with atorvastatin in patients with cholestatic liver disease.
ATHEROSCLER SUPPL 2008; 9(1):197-197.-77th Congress of the European Atherosclerosis Society; APR 26-29, 2008; Istanbul, TURKEY. [Poster]

 

** Wagner, M; Zollner, G; Trauner, M Ischemia and cholestasis: more than (just) the bile ducts!
Transplantation. 2008; 85(8):1083-1085
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** Wagner, M; Zollner, G; Trauner, M Nuclear bile acid receptor farnesoid X receptor meets nuclear factor-kappaB: new insights into hepatic inflammation.
Hepatology. 2008; 48(5):1383-1386 [OPEN ACCESS]
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Wagner, M; Zollner, G; Trauner, M Beyond PXR and CAR, Regulations of Xenobiotic Metabolism by other nuclear receptors.
In: Xie, W; editors(s). Nuclear receptors in drug metabolism. Wiley & Sons; 2008. p. 275-300. (ISBN: 978-0-470-08679-7)

 

** Geier, A; Wagner, M; Dietrich, CG; Trauner, M Principles of hepatic organic anion transporter regulation during cholestasis, inflammation and liver regeneration.
Biochim Biophys Acta. 2007; 1773(3): 283-308. [OPEN ACCESS]
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** Jahnel, J; Wagner, M; Langner, C; Hoegenauer, C; Fickert, P; Silbert, D; Gumhold, J; Fuchsbichler, A; Denk, H; Trauner, M Impact of colitis on bile secretion and hepatobiliary transporter expression in mice possible implications for pathogenesis of sclerosing cholangitis
J HEPATOL. 2007; 46: S122-S122. [Poster]
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** Marschall, HU; Wagner, M; Zollner, G; Trauner, M Clinical hepatotoxicity. Regulation and treatment with inducers of transport and cofactors.
MOL PHARM. 2007; 4(6): 895-910.
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** Stojakovic, T; Putz-Bankuti, C; Fauler, G; Scharnagl, H; Wagner, M; Stadlbauer, V; Gurakuqi, G; Stauber, RE; März, W; Trauner, M Atorvastatin in patients with primary biliary cirrhosis and incomplete biochemical response to ursodeoxycholic acid.
Hepatology. 2007; 46(3):776-784 [OPEN ACCESS]
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** Trauner, M; Fickert, P; Wagner, M MDR3 (ABCB4) defects: a paradigm for the genetics of adult cholestatic syndromes.
Semin Liver Dis. 2007; 27(1):77-98 [OPEN ACCESS]
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Trauner, M; Moustafa, T; Fickert, P; Halilbasic, E; Guelly, C; Fuchsbichler, A; Denk, H; Zatloukal, K; Wagner, M; Zollner, G Side chain-shortened bile acids for the treatment of cholestasis: lessons from nor-ursodeoxycholic acid.
In: Beuers, U; Keppler, D; Leuschner, U; Stiehl, A; Trauner, M; editors(s). Bile Acids: Biological Actions and Clinical Relevance. Dordrecht: Kluwer Academic Publishers; 2007. p. 75-80.

 

** Wagner, M; Moustafa, T; Fickert, P; Zollner, G; Gumhold, J; Silbert, D; Fuchsbichler, A; Zatloukal, K; Denk, H; Trauner, M Absence of FXR protects mice from bile-infarcts in biliary obstruction by reduction of bile acid-independent bile flow: Implications for targeting FXR in treatment of cholestasis?
J HEPATOL. 2007; 46: S5-S5.-42th Annual Meeting, European Association for the Study of the Liver; April, 11-15, 2007; Barcelona, Spain. [Oral Communication]
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Wagner, M; Trauner, M Physiology of bile formation.
In: Benhamou, JP; Blei, A; Dufour, JF; Friedman, S; Gines, P; Reichen, J; Rodes, J; Rizzetto, M; Valla, DC; Zoulim, F; editors(s). Textbook of Hepatology: From Basic Science to Clinical Practice (3rd edition). 2007. p. 290-304.

 

** Wagner, M; Zollner, G; Fickert, P; Gumhold, J; Silbert, D; Fuchsbichler, A; Gujral, JS; Zatloukal, K; Denk, H; Jaeschke, H; Trauner, M Hepatobiliary transporter expression in intercellular adhesion molecule 1 knockout and Fas receptor-deficient mice after common bile duct ligation is independent of the degree of inflammation and oxidative stress.
Drug Metab Dispos. 2007; 35(9):1694-1699 [OPEN ACCESS]
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** Zollner, G; Caligiuri, A; Fickert, P; Wagner, M; Silbert, D; Pinzani, M; Trauner, M Expression of bile acid transport and detoxification systems and their regulatory nuclear receptors in human hepatic stellate cells
J HEPATOL. 2007; 46: S135-S135.-42th Annual Meeting, European Association for the Study of the Liver ; April 11-15, 2007; Barcelona, Spain. [Poster]
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** Zollner, G; Wagner, M; Fickert, P; Silbert, D; Gumhold, J; Zatloukal, K; Denk, H; Trauner, M Expression of bile acid synthesis and detoxification enzymes and the alternative bile acid efflux pump MRP4 in patients with primary biliary cirrhosis.
Liver Int. 2007; 27(7):920-929
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** Ellis, E; Wagner, M; Lammert, F; Nemeth, A; Gumhold, J; Strassburg, CP; Kylander, C; Katsika, D; Trauner, M; Einarsson, C; Marschall, HU Successful treatment of severe unconjugated hyperbilirubinemia via induction of UGT1A1 by rifampicin.
J HEPATOL. 2006; 44(1): 243-245. (- Case Report)
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** Fickert, P; Fuchsbichler, A; Marschall, HU; Wagner, M; Zollner, G; Krause, R; Zatloukal, K; Jaeschke, H; Denk, H; Trauner, M Lithocholic acid feeding induces segmental bile duct obstruction and destructive cholangitis in mice.
Am J Pathol. 2006; 168(2):410-422 [OPEN ACCESS]
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** Fickert, P; Wagner, M; Marschall, HU; Fuchsbichler, A; Zollner, G; Tsybrovskyy, O; Zatloukal, K; Liu, J; Waalkes, MP; Cover, C; Denk, H; Hofmann, AF; Jaeschke, H; Trauner, M 24-norUrsodeoxycholic acid is superior to ursodeoxycholic acid in the treatment of sclerosing cholangitis in Mdr2 (Abcb4) knockout mice.
Gastroenterology. 2006; 130(2):465-481
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** Marschall, HU; Wagner, M; Bodin, K; Zollner, G; Fickert, P; Gumhold, J; Silbert, D; Fuchsbichler, A; Sjövall, J; Trauner, M Fxr(-/-) mice adapt to biliary obstruction by enhanced phase I detoxification and renal elimination of bile acids.
J Lipid Res. 2006; 47(3):582-592 [OPEN ACCESS]
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** Moustafa, T; Fickert, P; Prokesch, A; Wagner, M; Fuchsbichler, A; Silbert, D; Gumhold, J; Denk, H; Trajanoski, Z; Trauner, M Common bile-duct-ligation of FXR knockout mice results in severe hepatic steatosis due to enhancement in lipogenic gene expression
J HEPATOL. 44: S28-S28.-41st Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 26-30, 2006; Vienna, AUSTRIA. [Poster]
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** Zollner, G; Marschall, HU; Wagner, M; Trauner, M Role of nuclear receptors in the adaptive response to bile acids and cholestasis: pathogenetic and therapeutic considerations.
Mol Pharm. 2006; 3(3): 231-251.
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** Zollner, G; Wagner, M; Moustafa, T; Fickert, P; Silbert, D; Gumhold, J; Fuchsbichler, A; Halilbasic, E; Denk, H; Marschall, HU; Trauner, M Coordinated induction of bile acid detoxification and alternative elimination in mice: role of FXR-regulated organic solute transporter-alpha/beta in the adaptive response to bile acids.
Am J Physiol Gastrointest Liver Physiol. 2006; 290(5):G923-G932 [OPEN ACCESS]
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** Zollner, G; Wagner, M; Moustafa, T; Fickert, P; Silbert, D; Gumhold, J; Helmut, D; Marschall, HU; Trauner, M Role of nuclear bile acid receptor FXR in regulation of bile acid detoxification and organic solute transporter (OST-alpha/beta) expression in bile acid-fed mice
J HEPATOL. 44: S124-S124.-41st Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 26-30, 2006; Vienna, AUSTRIA. [Poster]
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** Fickert, P; Fuchsbichler, A; Wagner, M; Zollner, G; Krause, R; Zatloukal, K; Marschall, HU; Jaeschke, H; Denk, H; Trauner, M Lithocholic acid feeding induces biliary obstruction and destructive cholangitis in mice
J HEPATOL. 2005; 42: 113-113.-40th Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 13-17, 2005; Paris, FRANCE.
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** Fickert, P; Trauner, M; Fuchsbichler, A; Zollner, G; Wagner, M; Marschall, HU; Zatloukal, K; Denk, H Oncosis represents the main type of cell death in mouse models of cholestasis.
J Hepatol. 2005; 42(3):378-385
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** Fickert, P; Wagner, M; Marshall, HU; Fuchsbichler, A; Zollner, G; Zatloukal, K; Liu, J; Waalkes, MP; Cover, C; Denk, H; Hofmann, AF; Jaeschke, H; Trauner, M 24-norursodeoxycholic acid as novel therapeutic approach to sclerosing cholangitis in Mdr2 (ABCB4) knockout mice
HEPATOLOGY. 2005; 42: -56th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases; NOV 11-15, 2005; San Francisco, CA.
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** Geier, A; Zollner, G; Dietrich, CG; Wagner, M; Fickert, P; Denk, H; van Rooijen, N; Matern, S; Gartung, C; Trauner, M Cytokine-independent repression of rodent Ntcp in obstructive cholestasis.
Hepatology. 2005; 41(3):470-477 [OPEN ACCESS]
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** Geier, A; Zollner, G; Dietrich, CG; Wagner, M; Fickert, P; Denk, H; van Rooijen, N; Matern, S; Gartung, C; Trauner, M Cytokine-independent repression of rodent Ntcp in obstructive cholestasis
J HEPATOL. 2005; 42: 114-114.-40th Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 13-17, 2005; Paris, FRANCE.
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** Marschall, HU; Wagner, M; Zollner, G; Fickert, P; Diczfalusy, U; Gumhold, J; Silbert, D; Fuchsbichler, A; Benthin, L; Grundström, R; Gustafsson, U; Sahlin, S; Einarsson, C; Trauner, M Complementary stimulation of hepatobiliary transport and detoxification systems by rifampicin and ursodeoxycholic acid in humans.
Gastroenterology. 2005; 129(2):476-485
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** Marschall, HU; Wagner, M; Zollner, G; Fickert, P; Gumhold, J; Silbert, D; Diczfalusy, U; Benthin, L; Grundstrom, R; Gustafsson, U; Sahlin, S; Einarsson, C; Trauner, M Complementary stimulation of hepatobiliary transport and detoxification systems by rifampicin and ursodeoxycholic acid in human liver
GASTROENTEROLOGY. 2005; 128: A755-A755.
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Marschall, HU; Wagner, M; Zollner, G; Fickert, P; Gumhold, J; Silbert, D; Diczfalusy, U; Benthin, L; Grundström, R; Gustafsson, U; Sahlin, S; Einarsson, C; Trauner, M Comprehensive study of the effects of rifampicin and ursodeoxycholic acid on genes and proteins involved in regulation, transport and detoxification of biliary compounds in gallstone patients.
In: Keppler, D; Leuschner, U; Paumgartner, G; Stiehl, A; editors(s). Bile Acid Biology and its Therapeutic Implications. Dordrecht: Kluwer Academic Publishers; 2005. p. 219-225.

 

Trauner, M; Fickert, P; Halilbasic, E; Wagner, M; Zollner, G Molecular mechanisms of cholestasis.
In: Blumberg, RS; Gangl, A; Manns, MP; Tilg, H; Zeitz, M; editors(s). Gut-Liver Interactions: Basic and Clinical Concepts. Dordrecht: Kluwer Academic Publishers; 2005. p. 195-206.

 

Trauner, M; Fickert, P; Halilbasic, E; Wagner, M; Zollner, G Adaptive hepatobiliary transporter regulation by ursodeoxycholic acid.
In: Keppler, D; Leuschner, U; Paumgartner, G; Stiehl, A; editors(s). Bile Acid Biology and its Therapeutic Implications. Dordrecht: Kluwer Academic Publishers; 2005. p. 132-137.

 

** Trauner, M; Wagner, M; Fickert, P; Zollner, G Molecular regulation of hepatobiliary transport systems: clinical implications for understanding and treating cholestasis.
J Clin Gastroenterol. 2005; 39(4 Suppl 2):S111-S124 [OPEN ACCESS]
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** Wagner, M; Halilbasic, E; Marschall, HU; Zollner, G; Fickert, P; Langner, C; Zatloukal, K; Denk, H; Trauner, M CAR and PXR agonists stimulate hepatic bile acid and bilirubin detoxification and elimination pathways in mice.
Hepatology. 2005; 42(2):420-430 [OPEN ACCESS]
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** Wagner, M; Trauner, M Transcriptional regulation of hepatobiliary transport systems in health and disease: implications for a rationale approach to the treatment of intrahepatic cholestasis.
Ann Hepatol. 2005; 4(2): 77-99.
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** Wagner, M; Zollner, G; Fickert, P; Gumhold, J; Silbert, D; Fuchsbichler, A; Gujral, J; Zatloukal, K; Jaeschke, H; Deck, H; Trauner, M Role of inflammation for hepatobiliary transporter expression in ICAM-/- and lpr mice after common bile duct ligation
GASTROENTEROLOGY. 2005; 128: A89-A89.
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** Wagner, M; Zollner, G; Fickert, P; Gumhold, J; Silbert, D; Fuchsbichler, A; Gujral, JS; Zatloukal, K; Denk, H; Jaeschke, H; Trauner, M Alterations of hepatobiliary transporter expression in response to common bile duct ligation in mice are independent of ICAM-1 and FAS-receptor expression
J HEPATOL. 2005; 42: 115-115.-40th Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 13-17, 2005; Paris, FRANCE.
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** Zollner, G; Wagner, M; Fickert, P; Geier, A; Fuchsbichler, A; Silbert, D; Gumhold, J; Zatloukal, K; Kaser, A; Tilg, H; Denk, H; Trauner, M Role of nuclear receptors and hepatocyte-enriched transcription factors for Ntcp repression in biliary obstruction in mouse liver.
Am J Physiol Gastrointest Liver Physiol. 2005; 289(5):G798-G805 [OPEN ACCESS]
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** Zollner, G; Wagner, M; Fickert, P; Gumhold, J; Silbert, D; Marschall, HU; Denk, H; Trauner, M Expression of key bile acid detoxification enzymes and the alternative bile acid export pump MRP4 in primary biliary cirrhosis
J HEPATOL. 2005; 42: 240-240.-40th Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 13-17, 2005; Paris, FRANCE.
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** Zollner, G; Wagner, M; Fickert, P; Gumhold, J; Silbert, D; Marschall, HU; Denk, H; Trauner, M Expression of bile acid synthesis and detoxification enzymes and the alternative bile acid efflux pump MRP4 in patients with primary biliary cirrhosis
GASTROENTEROLOGY. 2005; 128: A691-A691.
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** Zollner, G; Wagner, M; Fickert, P; Silbert, D; Fuchsbichler, A; Zatloukal, K; Denk, H; Trauner, M Hepatobiliary transporter expression in human hepatocellular carcinoma.
Liver Int. 2005; 25(2):367-379
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** Fickert, P; Fuchsbichler, A; Wagner, M; Zollner, G; Kaser, A; Tilg, H; Krause, R; Lammert, F; Langner, C; Zatloukal, K; Marschall, HU; Denk, H; Trauner, M Regurgitation of bile acids from leaky bile ducts causes sclerosing cholangitis in Mdr2 (Abcb4) knockout mice.
Gastroenterology. 2004; 127(1):261-274
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** Fickert, P; Fuchsbichler, A; Wagner, M; Zollner, G; Kaser, A; Tilg, H; Krause, R; Langner, C; Zatloukal, K; Marschall, HU; Denk, H; Trauner, M Bile acids regurgitation from leaky bile ducts causes sclerosing cholangitis in Mdr2 knockout mice
GASTROENTEROLOGY. 2004; 126: A663-A663.
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** Fickert, P; Fuchsbichler, A; Wagner, M; Zollner, G; Kaser, A; Tilg, H; Krause, R; Langner, C; Zatloukal, K; Marschall, HU; Denk, H; Trauner, M Biliary leakage of fluorescent bile acids in MDR2 knockout mice: Evidence for a critical role of bile duct leakage in the pathogenesis of sclerosing cholangitis
J HEPATOL. 2004; 40: 91-91.-39th Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 14-18, 2004; Berlin, GERMANY.
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** Fickert, P; Trauner, M; Fuchsbichler, A; Zollner, G; Wagner, M; Marschall, HU; Zartloukal, K; Denk, H; Zsengeller, Z; Szabo, C Oncosis represents the main type of cell death in mouse models of cholestasis: evidence for a critical role of poly(ADP-ribose) polymerase (PARP) activation in bile acid-induced hepatocytes death
FASEB J. 2004; 18: A558-A558.-Experimental Biology 2004 Meeting; APR 17-21, 2004; Washington, DC.
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** Marschall, HU; Wagner, M; Zollner, G; Fickert, P; Gumhold, J; Silbert, D; Diczfalusy, U; Benthin, L; Grundstrom, R; Sahlin, S; Einarsson, C; Trauner, M Comprehensive study of the effects of rifampicin and ursodeoxycholic acid on genes and proteins involved in regulation, transport and detoxification of biliary compounds in gallstone patients
GASTROENTEROLOGY. 2004; 126: A746-A746.
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** Marschall, HU; Wagner, M; Zollner, G; Fickert, P; Gumholdt, J; Silbert, D; Diczfalusy, U; Benthin, L; Grundstrom, R; Sahlin, S; Einarsson, C; Trauner, M Comprehensive study of the effects of rifampicin and ursodeoxycholic acid on genes and proteins involved in regulation, transport and detoxification of biliary compounds in gallstone patients
J HEPATOL. 2004; 40: 93-93.-39th Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 14-18, 2004; Berlin, GERMANY.
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** Wagner, M; Fickert, P; Marschall, HU; Zollner, G; Silbert, D; Fuchsbichler, A; Gumhold, J; Schuetz, JD; Gonzalez, FJ; Zatloukal, K; Denk, H; Trauner, M Alternative exretory routes for accumulating bile acids via adaptive renal ABC transporter expression in common bile duct-ligated (CBDL) mice
GASTROENTEROLOGY. 2004; 126: A129-A130.
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** Wagner, M; Fickert, P; Zollner, G; Fuchsbichler, A; Gumhold, J; Silbert, D; Zatloukal, K; Gu, GL; Marschall, HU; Denk, H; Trauner, M Role of adaptive hepatobiliary transporter expression and regulation of bile acid synthetic enzymes in MDR2-/- mice: A model for chronic cholestatic liver disease due to sclerosing cholangitis
J HEPATOL. 2004; 40: 163-163.-39th Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 14-18, 2004; Berlin, GERMANY.
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** Wagner, M; Fickert, P; Zollner, G; Silbert, D; Fuchsbichler, A; Gumhold, J; Schuetz, JD; Gonzalez, FJ; Zatloukal, K; Marschall, HU; Denk, H; Trauner, M Adaptive renal ABC transporter expression in common bile duct-ligated mice
J HEPATOL. 2004; 40: 26-26.-39th Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 14-18, 2004; Berlin, GERMANY.
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** Wagner, M; Fickert, P; Zollner, G; Silbert, D; Gumhold, J; Fuchsbichler, A; Zatloukal, K; Marschall, HU; Denk, H; Trauner, M Gender and pregnancy affect hepatic and renal ABC transporter expression in mice
J HEPATOL. 2004; 40: 94-94.-39th Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 14-18, 2004; Berlin, GERMANY.
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** Wagner, M; Fickert, P; Zollner, G; Silbert, D; Gumhold, J; Fuchsbichler, A; Zatloukal, K; Marschall, HU; Denk, H; Trauner, M Hepatic and renal ABC transporter expression in mice depends on gender and changes in pregnancy
GASTROENTEROLOGY. 2004; 126: A130-A130.
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** Wagner, M; Halilbasic, E; Fickert, P; Zollner, G; Fuchsbichler, A; Gumhold, J; Silbert, D; Zatloukal, K; Denk, H; Trauner, M Nuclear receptor (PXR, CAR) agonists induce adaptive hepatic transporter and enzyme expression in mouse liver
J HEPATOL. 2004; 40: 25-25.-39th Annual Meeting of the European-Association-for-the-Study-of-the-Liver; APR 14-18, 2004; Berlin, GERMANY.
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** Wagner, M; Halilbasic, E; Zollner, G; Fickert, P; Gumhold, J; Silbert, D; Fuchsbichler, A; Zatloukal, K; Denk, H; Trauner, M Xenobiotic nuclear receptor (PXR, CAR) agonists coordinately stimulate a spectrum of detoxification enzymes and transport systems involved in the adaptive response to cholestasis in vivo.
HEPATOLOGY. 2004; 40: 489A-489A.-55th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD); OCT 29-NOV 02, 2004; Boston, MA.
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** Zollner, G; Halilbasic, E; Wagner, M; Fickert, P; Silbert, D; Gumhold, J; Fuchsbichler, A; Zatloukal, K; Denk, H; Trauner, M Differential effects of ursodeoxycholic acid (UDCA) and cholic acid (CA) on hepatic and renal expression of MRP4 and MRP6, two novel abc transporters, in mice
J HEPATOL. 2004; 40: 25-25.
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** Zollner, G; Halilbasic, E; Wagner, M; Fickert, P; Silbert, D; Gumhold, J; Fuchsbichler, A; Zatloukal, K; Denk, H; Trauner, M Cholic acid (CA) and ursodeoxycholic acid (UDCA) exert different effects on hepatic and renal expression of Mrp4 and Mrp6, two novel ABC transporters
GASTROENTEROLOGY. 2004; 126: A16-A16.
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** Zollner, G; Wagner, M; Fickert, P; Fuchsbichler, A; Gumhold, J; Silbert, D; Zatloukal, K; Guo, GL; Marschall, HU; Denk, H; Trauner, M Mdr2(-/-) mice with sclerosing cholangitis: A model of chronic cholestasis to study the role of the adaptive response of hepatobiliary transport systems and bile acid synthetic enzymes
GASTROENTEROLOGY. 2004; 126: A751-A751.
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** Fickert, P; Trauner, M; Fuchsbichler, A; Zollner, G; Wagner, M; Zenz, R; Zsengeller, Z; Szabo, C; Denk, H Inhibition of poly(ADP-ribose) polymerase (PARP) protects mice from cholestatic liver injury.
HEPATOLOGY 2003 38: 576A-576A.
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** Wagner, M; Fickert, P; Fuchsbichler, A; Silbert, D; Gumhold, J; Zollner, G; Zatloukal, K; Marschall, HU; Schuetz, JD; Gonzalez, FJ; Denk, H; Trauner, M Hepatic and renal ABC transporter expression as critical determinants of ursodeoxycholic acid-induced bile infarcts in bile duct-ligated mice.
HEPATOLOGY 2003 38: 688A-689A.
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** Wagner, M; Fickert, P; Zollner, G; Fuchsbichler, A; Silbert, D; Marschall, HU; Gonzalez, FJ; Zatloukal, K; Denk, H; Trauner, M The role of the bile acid receptor FXR in determining ATP-binding cassette (ABC) transporter expression and liver injury in common bile duct ligated (CBDL) mice
J HEPATOL 2003 38: 190-190.
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** Wagner, M; Fickert, P; Zollner, G; Fuchsbichler, A; Silbert, D; Tsybrovskyy, O; Gonzalez, FJ; Zatloukal, K; Marschall, HU; Denk, H; Trauner, M Role of nuclear bile acid receptor, FXR, in determining ATP-binding cassette (ABC) transporter expression and cholestatic liver injury in common bile duct-ligated mice
GASTROENTEROLOGY 2003 124: A697-A698.
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** Wagner, M; Fickert, P; Zollner, G; Fuchsbichler, A; Silbert, D; Tsybrovskyy, O; Zatloukal, K; Guo, GL; Schuetz, JD; Gonzalez, FJ; Marschall, HU; Denk, H; Trauner, M Role of farnesoid X receptor in determining hepatic ABC transporter expression and liver injury in bile duct-ligated mice.
Gastroenterology. 2003; 125(3):825-838
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** Wagner, M; Kaufmann, P; Fickert, P; Trauner, M; Lackner, C; Stauber, RE Successful conservative management of acute hepatic failure following exertional heatstroke.
Eur J Gastroenterol Hepatol. 2003; 15(10):1135-1139 (- Case Report)
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** Zollner, G; Fickert, P; Fuchsbichler, A; Silbert, D; Wagner, M; Arbeiter, S; Gonzalez, FJ; Marschall, HU; Zatloukal, K; Denk, H; Trauner, M Role of nuclear bile acid receptor, FXR, in adaptive ABC transporter regulation by cholic and ursodeoxycholic acid in mouse liver, kidney and intestine.
J Hepatol. 2003; 39(4):480-488
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** Zollner, G; Fickert, P; Silbert, D; Fuchsbichler, A; Wagner, M; Guo, G; Gonzalez, FJ; Zatloukal, K; Denk, H; Trauner, M Role of nuclear bile salt receptors Fxr and Pxr in mediating adaptive hepatobiliary transporter response to cholic acid (CA) in mouse liver
GASTROENTEROLOGY 2003 124: A59-A59.
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** Zollner, G; Fickert, P; Silbert, D; Fuchsbichler, A; Wagner, M; Zatloukal, K; Denk, H; Trauner, M Role of short heterodimer partner (SHP) -dependent and -independent pathways for regulation of Na+/taurocholate cotransporter (NTCP) expression in cholestatic mouse models.
J HEPATOL. 2003; 38(2):9-10.-38th Annual Meeting of the European-Association-for-the-Study-of-the-Liver; MAR 29-APR 01, 2003; ISTANBUL, TURKEY.
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** Zollner, G; Fickert, P; Silbert, D; Fuchsbichler, A; Wagner, M; Zatloukal, K; Denk, H; Trauner, M Regulation of the Na+/taurocholate cotransporter Ntcp via short heterodimer partner (SHP)-dependent or SHP-independent mechanims depends on the type of cholestatic injury
GASTROENTEROLOGY 2003 124: A730-A730.
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** Zollner, G; Fickert, P; Wagner, M; Fuchsbichler, A; Silbert, D; Gumhold, J; Zatloukal, K; Denk, H; Trauner, M Induction of intestinal multidrug resistance-associated proteins 2 and 3 (Mrp2, Mrp3) by cholic acid (CA) and ursodeoxycholic acid (UDCA) in mice.
HEPATOLOGY 2003 38: 689A-689A.
Web of Science

 

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