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Dengler Michael |

Präsentationen bei wissenschaftlichen und nicht-wissenschaftlichen Veranstaltungen

Dengler, MA BOK promotes KRAS-driven lung tumorigenesis in a p53-dependent manner
Death in the Alps 2022; JAN 15-19; Obergurgl, Austria. 2022. [Oral Communication]

 

Dengler, MA; Pal, M; Herold, MJ; Adams, JM; Jost, PJ Identifying novel regulators of BCL-XL as targets for therapy-resistant cancer
Gordon Research Conference - Cell Death: Cell Death-Associated Inflammation in Disease ; MAY 15-20, 2022 ; Les Diablerets, Switzerland. 2022. [Poster]

 

Krajina, K; Kapeller, A; Dengler, M; Jost, P; Pichler, M; Klec, C The long non-coding RNA NORAD and its relevance on PARP inhibitor sensitivity in triple negative breast cancer
Proceedings of the Annual Meeting of the Austrian Society of Haematology and Medical Oncology. 2022; -OeGHO- & AHOP-Frühjahrstagung 2022; APR 8-10, 2022; Graz, AUSTRIA. [Poster]

 

Szmyra, MM; Haingartner, S; Jantscher, S; Pansy, K; Uhl, B; Greinix, HT; Neumeister, P; Bernhart, E; Beham-Schmid, C; Dengler, MA; Klosch, B; Deutsch, AJA The Flavonoid Brusatol Induces Apoptosis in Aggressive Lymphoma Cells and Exhibits Synergistic Effect with Venetoclax
BLOOD. 2022; 140: 4945-4946. Doi: 10.1182/blood-2022-166678 [Poster]
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Dengler, MA Using CRISPR/Cas9 Tools to Identify New Targets for Cancer Treatment
Cell Culture Days 2021; OCT 4-5; Graz, AUSTRIA. 2021. [Onlinepräsentation]

 

Jäger, V; Jost, P; Dengler, M Molecular mechanisms of transformtion in lung cancer
11th Scientific Retreat of the DK-MCD; SEP 27-29, 2021; Seggau; AUSTRIA. 2021. [Oral Communication]

 

Dengler, MA; Herold, MJ; Adams, JM Genetic and pharmacological targeting of the pro-survival protein Mcl-1 in mantle cell lymphoma
New Frontiers in Cancer Research 2018 – 2nd Annual Victorian Comprehensive Cancer Centre (VCCC) Postdoctoral Symposium; JUN 1st, 2018; Melbourne, Australia. 2018. [Oral Communication]

 

Dengler, MA; Herold, MJ; Roberts, AW; Adams, JM The pro-survial protein Mcl-1 as a therapeutic target in mantle cell lymphoma
Lorne Cancer Conference 2018; FEB 8-10, 2018; Lorne, Australia. 2018. [Oral Communication]

 

Dengler, MA; Robin, AY; Gibson, L; Li, MX; Sandow, JS; Webb, AI; Iyer, S; Westphal, D; Dewson, G; Adams, JM BAX activation for apoptosis: mutations near its proposed non-canonical BH3 binding site reveal allosteric changes controlling mitochondrial association
Cell Death Discovery. 2018; -26th Conference of the European Cell Death Organization (ECDO): Cell death in disease — from small molecules to translational medicine; OCT 10-12, 2018; St. Petersburg, RUSSIA. [Poster]
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Dengler, MA; Teh, CE; Herold, MJ; Roberts, AW; Adams, JM Targeting Mcl-1 is a promising strategy to kill mantle cell lymphoma cells.
Cell Death Discovery. 2018; -26th Conference of the European Cell Death Organization (ECDO): Cell death in disease — from small molecules to translational medicine; OCT 10-12, 2018; St. Petersburg, RUSSIA. [Oral Communication]
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Dengler, MA; Gibson, L; Adams, JM Functional insights into the role of a potential alternative BH3 binding site for Bax activation
Gordon Research Conference, Cell Death; July 3-8, 2016; Girona, Spain. 2016. [Poster]

 

Dengler, MA; Gibson, L; Adams, JM Investigating the early steps of Bax activation for apoptosis: How does the proposed Bax ‘rear’ site contribute?
Japan Australia Meeting on Cell Death; OCT 21-23; Melbourne, Australia. 2015. [Poster]

 

Dengler, MA; Weilbacher, A; Gutekunst, M; Staiger, AM; Horn, H; Ott, G; van der Kuip, H; Aulitzky; WE he Phenotype High Noxa mRNA/Low NOXA Protein Levels Constitutes a Critical Achilles Heel Of Mantle Cell Lymphoma (MCL) Cells
Blood 2013; 122 (21): 644. 2013; -American Society of Hematology (ASH) 55th Annual Meeting; DEC 7-10; New Orleans, USA. [Oral Communication]
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Dengler, MA; Weilbacher, A; Gutekunst, M; Staiger, AM; Horn, H; Ott, G; van der Kuip, H; Aulitzky, WE High NOXA (PMAIP1) transcript levels combined with a short-lived NOXA protein primes mantle cell lymphoma (MCL) cells for death by inhibition of the ubiquitin proteasome system.
Cancer Research 15 April 2013; 73 (8_Supplement): 1717. 2013; -104th Annual Meeting of the American Association for Cancer Research (AACR); April 6-10, 2013; Washington, DC, USA. [Poster]

 

Gutekunst, M; Mueller, T; Weilbacher, A; Dengler, MA; Oren, M; Aulitzky, WE; van der Kuip, H Testicular germ cell tumors are hypersensitive to p53 activation based on their Oct-4/Noxa-mediated cellular context rather than on differential p53 activity.
Cancer Research 15 April 2013; 73 (8_Supplement): 1721. . 2013; -104th Annual Meeting of the American Association for Cancer Research (AACR); April 6-10, 2013; Washington, DC, USA. [Poster]

 

Weilbacher, A; Gutekunst, M; Dengler, MA; van der Kuip, H; Aulitzky WE Role of constitutive levels of Bcl-2 family proteins for cisplatin sensitivity
ONKOLOGIE (Vol. 36, pp. 282-283). 2013; -Jahrestagung der DGHO, ÖGHO, SGMO und SGH; OKT 18-22, 2013; Vienna, Austria. [Poster]

 

Dengler, M;, Gutekunst, M; Staiger, AS; Kopacz, S; Ott, G; van der Kuip, H; Aulitzky, WE. Fatty acid metabolism is a possible target for treatment of cyclin D1 over-expressing mantle cell lymphoma
Cancer Research 15 April 2012; 72 (8_Supplement): 4675. 2012; -103rd Annual Meeting of the American Association for Cancer Research (AACR); MAR 31 - APR 4; Chicago, USA. [Poster]

 

Dengler, MA; Gutekunst, M; A Staiger, A; Horn, H; Ott, G; Aulitzky, WE; van der Kuip, H Fatty acid metabolism as a promising target for treatment of mantle cell lymphoma
ONKOLOGIE. 2012; 35: 42-42.-Jahrestagung der DGHO, OeGHO, SGMO und SGH, 2012; OCT 19-23; Stuttgart, Germany. [Poster]

 

Gutekunst, M; Mueller, T; Weilbacher, A; Dengler, MA; Bedke, J; Kruck, S; van der Kuip, H; Aulitzky, WE Oct-4-dependent high constitutive Noxa determines p53-mediated Cisplatin hypersensitivity in testicular germ cell tumors
ONKOLOGIE. 2012; 35: 183-183.-Jahrestagung der DGHO, OeGHO, SGMO und SGH, ; OCT 19-23; Stuttgart, Germany. [Poster]

 

Gutekunst, M; Mueller, T; Weilbacher, A; Dengler, MA; Kruck, S; Bedke, J; Aulitzky, WE; van der Kuip, H OCT-3/4 expression is associated with high levels of the pro-apoptotic BH3 only protein NOXA in testicular germ cell tumors (TGCTs)
Cancer Research 15 April 2012; 72 (8_Supplement): 2002. 2012; -103rd Annual Meeting of the American Association for Cancer Research (AACR); MAR 31 - APR 4, 2012; Chicago, USA. [Poster]

 

Dengler, M;, Gutekunst, M; Kopacz, S; Horn, H; Hofmann, U; Schwab, M; Ott, G; van der Kuip, H; Aulitzky, WE. Cyclin D1 Over-Expressing Mantle Cell Lymphoma Cells Are Hypersensitive to Inhibition of Fatty Acid Synthase (FASN).
Blood 2011; 118 (21): 1656.. 2011; -53rd ASH Annual Meeting in ; DEC 10-13, 2011; San Diego, USA. [Poster]

 

Dengler, MA; Staiger, A; Gutekunst, M; Hofmann, U; Aulitzky, WE; van der Kuip, H. Oncogenic stress induced by Bcr-Abl over-activation leads to cell death mediated by a massively enhanced glycolysis
Cancer Research 15 April 2011; 71 (8_Supplement): 1266.. 2011; -102nd Annual Meeting of the American Association for Cancer Research (AACR); Apr 2-6, 2011; Orlando, USA. [Poster]

 

Gutekunst, M; Oren, M; Weilbacher, A; Dengler, MA; Staiger, AM; Aulitzky, WE; van der Kuip, H. High expression levels of NOXA are important for p53-mediated hypersensitivity in testicular germ cell tumor (TGCT) cells
Cancer Research 15 April 2011; 71 (8_Supplement): 4693. . 2011; -102nd Annual Meeting of the American Association for Cancer Research (AACR); Apr 2-6, 2011; Orlando, USA. [Poster]

 

Dengler, M; Staiger, A; Gutekunst, M; van der Kuip, H; Aulitzky, W Bcr-Abl-mediated oncogenic stress induces ER stress response and a programmed necrosis-like cell death in Bcr-Abl overexpressing Imatinib-resistant ALL cells
Onkologie 33, 211-212. 2010; -Jahrestagung der DGHO, OeGHO, SGMO und SGH; OKT 1-5, 2010; Berlin. [Oral Communication]

 

Dengler, MA; Staiger, AM; Gutekunst, M; Aulitzky, WE; van der Kuip, H Oncogenic stress-induced cell death following Imatinib deprivation in Bcr-Abl overexpressing Imatinib-resistant ALL cells
Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC. 2010; -AACR 101st Annual Meeting; Washington, DC; APR 17 -21, 2010; Washington, DC, USA. [Poster]
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Dengler, MA; Staiger, AM; Hofmann, U; Gutekunst, M; van der Kuip, H; Aulitzky, W Glucocorticoids Inhibit Cell Death Induced by Oncogenic Stress After Imatinib Withdrawal In TKI Resistant p190Bcr/Abl Overexpressing Cells
Blood, The Journal of the American Society of Hematology. 2010; 116(21):3150-3150.-American Society of Hematology (ASH) 52nd Annual Meeting; DEC 4-7, 2010; Orlando, USA. [Poster]
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Gutekunst, M; Markwardt, C; Dengler, M; van der Kuip, H; Aulitzky, W Cisplatin-hypersensitivity of NTERA cells is mediated through a CHK2/p53 dependent activation of NOXA
Onkologie 33. 2010; -Jahrestagung der DGHO, ÖGHO, SGMO und SGH; OKT 1-5, 2010; Berlin, Germany. [Oral Communication]

 

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