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Division of Medical Physics and Biophysics

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** = Publications listed in SCI/SSCI/Pubmed

Full paper/article (Journal)

** Andronache, IC; Ahammer, H; Jelinek, HF; Peptenatu, D; Ciobotaru, AM; Draghici, CC; Pintilii, RD; Simion, AG; Teodorescu, C Fractal analysis for studying the evolution of forests
CHAOS SOLITON FRACT. 2016; 91: 310-318. Doi: 10.1016/j.chaos.2016.06.013
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** Augustin, CM; Crozier, A; Neic, A; Prassl, AJ; Karabelas, E; Ferreira da Silva, T; Fernandes, JF; Campos, F; Kuehne, T; Plank, G Patient-specific modeling of left ventricular electromechanics as a driver for haemodynamic analysis.
Europace. 2016; 18(suppl 4):iv121-iv129-iv121-iv129 Doi: 10.1093/europace/euw369 [OPEN ACCESS]
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** Augustin, CM; Neic, A; Liebmann, M; Prassl, AJ; Niederer, SA; Haase, G; Plank, G Anatomically accurate high resolution modeling of human whole heart electromechanics: A strongly scalable algebraic multigrid solver method for nonlinear deformation.
J Comput Phys. 2016; 305(suppl 4):622-646 Doi: 10.1016/j.jcp.2015.10.045 [OPEN ACCESS]
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** Bishop, M; Rajani, R; Plank, G; Gaddum, N; Carr-White, G; Wright, M; O'Neill, M; Niederer, S Three-dimensional atrial wall thickness maps to inform catheter ablation procedures for atrial fibrillation.
Europace. 2016; 18(3):376-383 Doi: 10.1093/europace/euv073 [OPEN ACCESS]
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** Chamakuri, N; Kunisch, K; Plank, G PDE constrained optimization of electrical defibrillation in a 3D ventricular slice geometry.
Int J Numer Method Biomed Eng. 2016; 32(4):e02742-e02742 Doi: 10.1002/cnm.2742
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** Chauvet, S; Jarvis, L; Chevallet, M; Shrestha, N; Groschner, K; Bouron, A Pharmacological Characterization of the Native Store-Operated Calcium Channels of Cortical Neurons from Embryonic Mouse Brain.
Front Pharmacol. 2016; 7(1):486-486 Doi: 10.3389/fphar.2016.00486 [OPEN ACCESS]
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** Costa, CM; Silva, PA; dos Santos, RW Mind the Gap: A Semicontinuum Model for Discrete Electrical Propagation in Cardiac Tissue.
IEEE Trans Biomed Eng. 2016; 63(4):765-774 Doi: 10.1109/TBME.2015.2470256
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** Crozier, A; Augustin, CM; Neic, A; Prassl, AJ; Holler, M; Fastl, TE; Hennemuth, A; Bredies, K; Kuehne, T; Bishop, MJ; Niederer, SA; Plank, G Image-Based Personalization of Cardiac Anatomy for Coupled Electromechanical Modeling.
Ann Biomed Eng. 2016; 44(1):58-70 Doi: 10.1007/s10439-015-1474-5 [OPEN ACCESS]
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** Crozier, A; Blazevic, B; Lamata, P; Plank, G; Ginks, M; Duckett, S; Sohal, M; Shetty, A; Rinaldi, CA; Razavi, R; Niederer, SA; Smith, NP Analysis of lead placement optimization metrics in cardiac resynchronization therapy with computational modelling.
Europace. 2016; 18(suppl 4):iv113-iv120-iv113-iv120 Doi: 10.1093/europace/euw366 [OPEN ACCESS]
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** Derler, I; Jardin, I; Stathopulos, PB; Muik, M; Fahrner, M; Zayats, V; Pandey, SK; Poteser, M; Lackner, B; Absolonova, M; Schindl, R; Groschner, K; Ettrich, R; Ikura, M; Romanin, C Cholesterol modulates Orai1 channel function.
Sci Signal. 2016; 9(412):ra10-ra10 Doi: 10.1126/scisignal.aad7808 [OPEN ACCESS]
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** Eroglu, E; Gottschalk, B; Charoensin, S; Blass, S; Bischof, H; Rost, R; Madreiter-Sokolowski, CT; Pelzmann, B; Bernhart, E; Sattler, W; Hallström, S; Malinski, T; Waldeck-Weiermair, M; Graier, WF; Malli, R Development of novel FP-based probes for live-cell imaging of nitric oxide dynamics.
Nat Commun. 2016; 7(3):10623-10623 Doi: 10.1038/ncomms10623 [OPEN ACCESS]
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** Folci, A; Murru, L; Vezzoli, E; Ponzoni, L; Gerosa, L; Moretto, E; Longo, F; Zapata, J; Braida, D; Pistillo, F; Bähler, M; Francolini, M; Sala, M; Bassani, S Myosin IXa Binds AMPAR and Regulates Synaptic Structure, LTP, and Cognitive Function.
Front Mol Neurosci. 2016; 9(2):1-1 Doi: 10.3389/fnmol.2016.00001 [OPEN ACCESS]
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** Hill, YR; Child, N; Hanson, B; Wallman, M; Coronel, R; Plank, G; Rinaldi, CA; Gill, J; Smith, NP; Taggart, P; Bishop, MJ Investigating a Novel Activation-Repolarisation Time Metric to Predict Localised Vulnerability to Reentry Using Computational Modelling.
PLoS One. 2016; 11(3):e0149342-e0149342 Doi: 10.1371/journal.pone.0149342 [OPEN ACCESS]
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** Hofer, E; Arnold, R; Reishofer, G; Ahammer, H Track Z. Training and Further Education for Engineers and Physicians.
Biomed Tech (Berl). 2016; 61(s1):262-266 Doi: 10.1515/bmt-2016-5024 [Oral Communication]
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** Kammerer, S; Jahn, SW; Winter, E; Eidenhammer, S; Rezania, S; Regitnig, P; Pichler, M; Schreibmayer, W; Bauernhofer, T Critical evaluation of KCNJ3 gene product detection in human breast cancer: mRNA in situ hybridisation is superior to immunohistochemistry.
J Clin Pathol. 2016; 69(12):1116-1121 Doi: 10.1136/jclinpath-2016-203798 [OPEN ACCESS]
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** Kammerer, S; Sokolowski, A; Hackl, H; Platzer, D; Jahn, SW; El-Heliebi, A; Schwarzenbacher, D; Stiegelbauer, V; Pichler, M; Rezania, S; Fiegl, H; Peintinger, F; Regitnig, P; Hoefler, G; Schreibmayer, W; Bauernhofer, T KCNJ3 is a new independent prognostic marker for estrogen receptor positive breast cancer patients.
Oncotarget. 2016; 7(51):84705-84717 Doi: 10.18632/oncotarget.13224 [OPEN ACCESS]
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** Kornmueller, K; Lehofer, B; Meindl, C; Fröhlich, E; Leitinger, G; Amenitsch, H; Prassl, R Peptides at the Interface: Self-Assembly of Amphiphilic Designer Peptides and Their Membrane Interaction Propensity.
Biomacromolecules. 2016; 17(11):3591-3601 Doi: 10.1021/acs.biomac.6b01089 [OPEN ACCESS]
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** Lohberger, B; Steinecker-Frohnwieser, B; Stuendl, N; Kaltenegger, H; Leithner, A; Rinner, B The Proteasome Inhibitor Bortezomib Affects Chondrosarcoma Cells via the Mitochondria-Caspase Dependent Pathway and Enhances Death Receptor Expression and Autophagy.
PLoS One. 2016; 11(12):e0168193-e0168193 Doi: 10.1371/journal.pone.0168193 [OPEN ACCESS]
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** Marée, R; Rollus, L; Stévens, B; Hoyoux, R; Louppe, G; Vandaele, R; Begon, JM; Kainz, P; Geurts, P; Wehenkel, L Collaborative analysis of multi-gigapixel imaging data using Cytomine.
Bioinformatics. 2016; 32(9):1395-1401 Doi: 10.1093/bioinformatics/btw013 [OPEN ACCESS]
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** Matuszak, J; Baumgartner, J; Zaloga, J; Juenet, M; da Silva, AE; Franke, D; Almer, G; Texier, I; Faivre, D; Metselaar, JM; Navarro, FP; Chauvierre, C; Prassl, R; Dézsi, L; Urbanics, R; Alexiou, C; Mangge, H; Szebeni, J; Letourneur, D; Cicha, I Nanoparticles for intravascular applications: physicochemical characterization and cytotoxicity testing.
Nanomedicine (Lond). 2016; 11(6):597-616 Doi: 10.2217/nnm.15.216 [OPEN ACCESS]
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** Mayrhofer-Reinhartshuber, M; Ahammer, H Pyramidal fractal dimension for high resolution images.
Chaos. 2016; 26(7):073109-073109 Doi: 10.1063/1.4958709
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** Müller, W; Lohman, TG; Stewart, AD; Maughan, RJ; Meyer, NL; Sardinha, LB; Kirihennedige, N; Reguant-Closa, A; Risoul-Salas, V; Sundgot-Borgen, J; Ahammer, H; Anderhuber, F; Fürhapter-Rieger, A; Kainz, P; Materna, W; Pilsl, U; Pirstinger, W; Ackland, TR Subcutaneous fat patterning in athletes: selection of appropriate sites and standardisation of a novel ultrasound measurement technique: ad hoc working group on body composition, health and performance, under the auspices of the IOC Medical Commission.
Br J Sports Med. 2016; 50(1):45-54 Doi: 10.1136/bjsports-2015-095641 [OPEN ACCESS]
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** Patriarchi, T; Qian, H; Di Biase, V; Malik, ZA; Chowdhury, D; Price, JL; Hammes, EA; Buonarati, OR; Westenbroek, RE; Catterall, WA; Hofmann, F; Xiang, YK; Murphy, GG; Chen, CY; Navedo, MF; Hell, JW Phosphorylation of Cav1.2 on S1928 uncouples the L-type Ca2+ channel from the β2 adrenergic receptor.
EMBO J. 2016; 35(12):1330-1345 Doi: 10.15252/embj.201593409 [OPEN ACCESS]
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** Pelzmann, B; Di Giuro, CM; Zorn-Pauly, K; Rossmann, C; Hallström, S; Groschner, K; Fameli, N Functional impairment of endothelial cells by the antimycotic amphotericin B.
Biochem Biophys Res Commun. 2016; 472(1):40-45 Doi: 10.1016/j.bbrc.2016.02.054
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** Poteser, M; Leitinger, G; Pritz, E; Platzer, D; Frischauf, I; Romanin, C; Groschner, K Live-cell imaging of ER-PM contact architecture by a novel TIRFM approach reveals extension of junctions in response to store-operated Ca2+-entry.
Sci Rep. 2016; 6(S 01):35656-35656 Doi: 10.1038/srep35656 [OPEN ACCESS]
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** Rasoulzadeh, Z; Ghods, R; Kazemi, T; Mirzadegan, E; Ghaffari-Tabrizi-Wizsy, N; Rezania, S; Kazemnejad, S; Arefi, S; Ghasemi, J; Vafaei, S; Mahmoudi, AR; Zarnani, AH Placental Kisspeptins Differentially Modulate Vital Parameters of Estrogen Receptor-Positive and -Negative Breast Cancer Cells.
PLoS One. 2016; 11(4):e0153684-e0153684 Doi: 10.1371/journal.pone.0153684 [OPEN ACCESS]
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** Reiss, MA; Lemmerer, B; Hanslmeier, A; Ahammer, H Tug-of-war lacunarity-A novel approach for estimating lacunarity.
Chaos. 2016; 26(11):113102-113102 Doi: 10.1063/1.4966539 [OPEN ACCESS]
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** Rezania, S; Kammerer, S; Li, C; Steinecker-Frohnwieser, B; Gorischek, A; DeVaney, TT; Verheyen, S; Passegger, CA; Tabrizi-Wizsy, NG; Hackl, H; Platzer, D; Zarnani, AH; Malle, E; Jahn, SW; Bauernhofer, T; Schreibmayer, W Overexpression of KCNJ3 gene splice variants affects vital parameters of the malignant breast cancer cell line MCF-7 in an opposing manner.
BMC Cancer. 2016; 16(1):628-628 Doi: 10.1186/s12885-016-2664-8 [OPEN ACCESS]
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** Roier, S; Zingl, FG; Cakar, F; Durakovic, S; Kohl, P; Eichmann, TO; Klug, L; Gadermaier, B; Weinzerl, K; Prassl, R; Lass, A; Daum, G; Reidl, J; Feldman, MF; Schild, S A novel mechanism for the biogenesis of outer membrane vesicles in Gram-negative bacteria.
Nat Commun. 2016; 7:10515 Doi: 10.1038/ncomms10515 [OPEN ACCESS]
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** Tiapko, O; Bacsa, B; de la Cruz, GG; Glasnov, T; Groschner, K Optopharmacological control of TRPC channels by coumarin-caged lipids is associated with a phototoxic membrane effect.
Sci China Life Sci. 2016; 59(8):802-810 Doi: 10.1007/s11427-016-5095-5 [OPEN ACCESS]
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** Verbrugge, SE; Al, M; Assaraf, YG; Kammerer, S; Chandrupatla, DM; Honeywell, R; Musters, RP; Giovannetti, E; O'Toole, T; Scheffer, GL; Krige, D; de Gruijl, TD; Niessen, HW; Lems, WF; Kramer, PA; Scheper, RJ; Cloos, J; Ossenkoppele, GJ; Peters, GJ; Jansen, G Multifactorial resistance to aminopeptidase inhibitor prodrug CHR2863 in myeloid leukemia cells: down-regulation of carboxylesterase 1, drug sequestration in lipid droplets and pro-survival activation ERK/Akt/mTOR.
Oncotarget. 2016; 7(5):5240-5257 Doi: 10.18632/oncotarget.6169 [OPEN ACCESS]
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** Zach, B; Hofer, E; Asslaber, M; Ahammer, H Automated Texture Analysis and Determination of Fibre Orientation of Heart Tissue: A Morphometric Study.
PLoS One. 2016; 11(8):e0160735-e0160735 Doi: 10.1371/journal.pone.0160735 [OPEN ACCESS]
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Short report/Letter

** Platzer, D; Zorn-Pauly, K Letter to the editor: Accurate cell capacitance determination from a single voltage step: a reminder to avoid unnecessary pitfalls.
Am J Physiol Heart Circ Physiol. 2016; 311(4): H1072-H1073. Doi: 10.1152/ajpheart.00503.2016 [OPEN ACCESS]
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Review

** Crozier, A; Blazevic, B; Lamata, P; Plank, G; Ginks, M; Duckett, S; Sohal, M; Shetty, A; Rinaldi, CA; Razavi, R; Smith, NP; Niederer, SA The relative role of patient physiology and device optimisation in cardiac resynchronisation therapy: A computational modelling study.
J Mol Cell Cardiol. 2016; 96(7):93-100 Doi: 10.1016/j.yjmcc.2015.10.026 [OPEN ACCESS]
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** Evans, AM; Fameli, N; Ogunbayo, OA; Duan, J; Navarro-Dorado, J From contraction to gene expression: nanojunctions of the sarco/endoplasmic reticulum deliver site- and function-specific calcium signals.
Sci China Life Sci. 2016; 59(8):749-763 Doi: 10.1007/s11427-016-5071-0 [OPEN ACCESS]
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** Svobodova, B; Groschner, K Reprint of "Mechanisms of lipid regulation and lipid gating in TRPC channels".
Cell Calcium. 2016; 60(2):133-141 Doi: 10.1016/j.ceca.2016.06.010
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** Svobodova, B; Groschner, K Mechanisms of lipid regulation and lipid gating in TRPC channels.
Cell Calcium. 2016; 59(6):271-279 Doi: 10.1016/j.ceca.2016.03.012 [OPEN ACCESS]
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Abstract (Journal)

** Cicha, I; Matuszak, J; Juenet, M; Chauvierre, C; Texier, I; Almer, G; Prassl, R; Metselaar, J; Dezsi, L; Urbanics, R; Szebeni, J; Alexiou, C; Mangge, H; Letourneur, D Novel nanosystems to combat atherosclerosis: Functional effects on human endothelial and monocytic cells
EUR HEART J. 2016; 37: 833-833.-Congress of the European-Society-of-Cardiology (ESC); AUG 27-31, 2016; Rome, ITALY. [Oral Communication]
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** Folci, A; Steinberger, A; Stanika, R; Campiglio, M; Ramprecht, C; Obermair, GJ; Heine, M; Di Biase, V Molecular Mimicking of Phosphorylation at S1928 and S1700-T1704 Confers Modified Surface Traffic Properties to CaV1.2 Voltage Gated Calcium Channels in Cultured Hippocampal Neurons
BIOPHYS J. 2016; 110(3):442A-442A.-60th Annual Meeting of the Biophysical-Society; FEB 27-MAR 02, 2016; Los Angeles, CA. Doi: 10.1016/j.bpj.2015.11.2379 [Poster]
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** Kolesnik, E; Koyani, C; Wallner, M; Khafaga, M; Scherubel, S; Djalinac, N; Sourij, H; Machler, H; Malle, E; Pelzmann, B; von Lewinski, D DPP-4 inhibitors impair contraction and relaxation in human atrial trabeculae and electrophysiological function in guinea pig ventricular cardiomyocytes
WIEN KLIN WOCHENSCHR. Wiener Klinische Wochenschrift, supplement 6/16. 2016; 128: S410-S412.-44. Jahrestagung der Österreichischen Diabetes Gesellschaft; NOV 17-19, 2016; Salzburg. [Oral Communication]
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** Lehofer, B; Golub, M; Kornmueller, K; Kriechbaum, M; Martinez, N; Amenitsch, H; Peters, J; Prassl, R Structural Effects of High Hydrostatic Pressure on Human Low Density Lipoprotein Revealed by Small Angle X-ray and Neutron Scattering
BIOPHYS J. 2016; 110(3):255A-256A.-60th Annual Meeting of the Biophysical-Society; FEB 27-MAR 02, 2016; Los Angeles, CA. Doi: 10.1016/j.bpj.2015.11.1403 [Poster]
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** Lohberger, B; Leithner, A; Stuendl, N; Kaltenegger, H; Kullich, W; Steinecker-Frohnwieser, B DIACEREIN RETARDS CELL GROWTH OF CHONDROSARCOMA CELLS AT THE G2/M CELL CYCLE CHECKPOINT VIA CYCLIN B1/CDK1 AND CDK2 DOWNREGULATION
OSTEOPOROSIS INT. 2016; 27: S142-S142. [Poster]
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** Meinitzer, A; Zelzer, S; Mangge, H; Almer, G; Prassl, R; Amouzadeh-Ghadikolai, O; Robier, C; Baranyi, A NITRIC OXIDE-RELATED CARDIOVASCULAR RISK FACTORS IN PATIENTS WITH MAJOR DEPRESSION
ATHEROSCLEROSIS. 2016; 252: E66-E66.-Congress of the European-Atherosclerosis-Society (EAS); MAY 29-JUN 01, 2016; Innsbruck, AUSTRIA. Doi: 10.1016/j.atherosclerosis.2016.07.451 [Poster]
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** Poteser, M; Bacsa, B; Tiapko, O; Lichtenegger, M; Frischauf, I; Romanin, C; Groschner, K TRPC3-Calcineurin Microdomains Govern Orai1 Signaling in Mast Cells
BIOPHYS J. 2016; 110(3):610A-610A.-60th Annual Meeting of the Biophysical-Society; FEB 27-MAR 02, 2016; Los Angeles, CA. Doi: 10.1016/j.bpj.2015.11.3258 [Poster]
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** Poteser, M; Pritz, E; Leitinger, G; Groschner, K Fluorescence Density Mapping: Extending the Possibilities of TIRFM to Study PM-ER Junctions
BIOPHYS J. 2016; 110(3):16A-16A.-60th Annual Meeting of the Biophysical-Society; FEB 27-MAR 02, 2016; Los Angeles, CA. Doi: 10.1016/j.bpj.2015.11.144 [Poster]
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** Schratter, G; Karbiener, M; Almer, G; Mangge, H; Scheideler, M; Prassl, R LIPOSOMES FOR MICRORNA DELIVERY TO HUMAN ADIPOCYTES
ATHEROSCLEROSIS. 2016; 252: E131-E131.-Congress of the European-Atherosclerosis-Society (EAS); MAY 29-JUN 01, 2016; Innsbruck, AUSTRIA. Doi: 10.1016/j.atherosclerosis.2016.07.672 [Poster]
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** Tamussino, K; Bliem, B; Tomasch, G; Greimel, E; Uranu, S; Bjelic-Radisic, V; Trutnovsky, G; Martina, L; Lang, P; Berger, A; Schauer, C; Oswald, S; Rosanelli, G WHAT DO WOMEN SCHEDULED FOR LAPAROSCOPIC CHOLECYSTECTOMY THINK ABOUT POTENTIAL PROPHYLACTIC SALPINGECTOMY?
INT J GYNECOL CANCER. 2016; 26: 32-32. [Oral Communication]
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** Tiapko, O; Glasnov, T; de la Cruz, GG; Poteser, M; Lichtenegger, M; Groschner, K Modulation of Neuronal Activity by Synthetic Activators of Lipid-Gated TRPC Channels
BIOPHYS J. 2016; 110(3):610A-610A.-60th Annual Meeting of the Biophysical-Society; FEB 27-MAR 02, 2016; Los Angeles, CA. Doi: 10.1016/j.bpj.2015.11.3259 [Poster]
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** Zelzer, S; Meinitzer, A; Enko, D; Almer, G; Prassl, R; Mangge, H BRANCHED-CHAIN AMINO ACID PROFILES INDICATE CARDIO METABOLIC RISK INDEPENDENT OF BODY MASS INDEX.
ATHEROSCLEROSIS. 2016; 252: E66-E67.-Congress of the European-Atherosclerosis-Society (EAS); MAY 29-JUN 01, 2016; Innsbruck, AUSTRIA. Doi: 10.1016/j.atherosclerosis.2016.07.452 [Poster]
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