Medizinische Universit├Ąt Graz - Research portal

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Division of Molecular Biology and Biochemistry

Research fields, Methods and Equipment

Research Fields


Adipocytes and obesity
Ageing and age-related diseases
Blood-brain barrier
Cellular lipid homeostasis
Cellular senescence
Clinical Chemisry
Endothelial function and vessel wall function
Genetic epidemiology and molecular mechanisms of human aging
Inflammation
Insulin/growth factor signalling
Lipid mediators in the signalling network and in gene expression
Lipid-and lipoprotein metabolism
Lipidomics
Lipotoxicity
Metabolomics
Metaboslism
Modified lipoproteins
Molecular modelling
Molecular pharmacology
Mytochondrial dysfunction
Nuclear import
Nuclear Magnetic Resonance Spectoscopy
Pathomechanisms and prevention of atherosclerosis
Rational drug design
Redox signalling
Regulation of cellular Ion equilibrium
RNA-binding proteins
SAXS
Signalling
Statistical Genetics
The role of Ca++ in cell function
type 2 diabetes mellitus
Wnt signaling

Methods


Animal experiments
Biophysical interaction studies
Cell culture
Chromatography
DNA cloning
Electrophoresis
Encyme activities
Gene expression
High throughput DNA/RNA Analysis
In vitro and in vivo gene transfer
Metabolomics
Micro arrays
Microscopy: Confocal laser scanning microscopy, Deconvolution microscopy
Molecular modelling
Next generation sequencing
NMR spektroscopy
Northern Blot analysis
PCR, RT-PCR
Production of antibodies
Programming
Protein expression and purification
Protein labelling
Proteomics
real time PCR
siRNA
Small-angle scattering
Southern Blot
Transfection of mammalian cells
Western Blot
wire myography

Equipment


blood pressure gauge - mouse,rat
confocal array scanning microscope
Gaschromatograph
GC-MS
Gel documentation system
HPLC
In-house SAXS machine (Anton Paar SAXSpace) equipped with a temperature-controlled autosampler (up to 2 x 96 samples), various sample holders, and detectors
Patch Clamp Technic (also applicable for all microscopes)
Pipetting robot (AndrewAlliance 1000P)
Pipetting roboter (Janus, PE)
Protein expression and purification platform, including FPLC (GE Healthcare Acta Pure)
Real Time PCR (ABI 7900)
ultra centrifuges
wire myography system
600 MHz NMR spetrometer (Bruker Biospin) equipped with BBI/TXI probeheads and a temperature-controlled autosampler (up to 500 samples)

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