Medizinische Universität Graz Austria - Forschungsportal - Medical University of Graz

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Gewählte Publikation:

Ferrara, G; Zalaudek, I; Savarese, I; Scalvenzi, M; Argenziano, G.
Pediatric atypical spitzoid neoplasms: a review with emphasis on 'red' ('spitz') tumors and 'blue' ('blitz') tumors.
Dermatology. 2010; 220(4):306-310 PubMed FullText FullText_MUG

Abstract:

BACKGROUND: The diagnosis of pediatric atypical Spitz nevus/tumors (pASNT) is an emerging challenge in clinical dermatology and dermatopathology. OBJECTIVE AND METHODS: We review the main clinicopathologic issues raised by pASNT and describe 2 examples of different clinicopathologic subsets of lesions. RESULTS: While Spitz/Reed nevi are commonly small- to medium-sized, tan to black plaques, pASNT are large and nodular, either 'red' (dotted and/or polymorphous vascular pattern on dermoscopy; spindle and/or epithelioid tumors on histopathology: Spitz tumors, sensu strictiori) or 'blue' (homogeneous blue color on dermoscopy; intimate admixture of epithelioid cells and heavily pigmented dendritic cells on histopathology: Blitz tumors or pigmented epithelioid melanocytomas). CONCLUSIONS: Different clinicopathologic settings of pASNT probably exist. Dermoscopy can aid in their recognition and classification.

Autor/innen der Med Uni Graz:

Zalaudek Iris

Gendermonitor

Find related publications in this database (Keywords)

Spitz nevus

Atypical Spitz nevus/tumor

Dermoscopy

Histopathology